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The map label for this gene is srtA

Identifier: 15675071

GI number: 15675071

Start: 888699

End: 888839

Strand: Direct

Name: srtA

Synonym: SPy_1083

Alternate gene names: 15675071

Gene position: 888699-888839 (Clockwise)

Preceding gene: 15675070

Following gene: 15675072

Centisome position: 47.97

GC content: 32.62

Gene sequence:

>141_bases
ATGAATAACACAATTAAAGACTTTGATCTCGATTTGAAAACAAATAAAAAAGACACTGCTACACCTTATGTTGGTAGCCG
TTACCTATGTACCCCTGGTTCTTGTTGGAAATTAGTTTGCTTTACAACAACTGTTAAATAA

Upstream 100 bases:

>100_bases
TTGGCTAAAATACTTTTTTTCTGAACAAATTCTGAACTTGGGGTGTCATAATAATCATGTAAATATATCGGATGCAAAAA
CGTAAGAGAGGAACTAGAAA

Downstream 100 bases:

>100_bases
TAAAGTTATCATTATCATAAACATTATAATTTCAAATAATTTTATATATTTATAAATTTAGGGGAGTAGACTGATTTTAG
TTTGCTCCTTTATTAGTAGA

Product: lantibiotic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 46; Mature: 46

Protein sequence:

>46_residues
MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK

Sequences:

>Translated_46_residues
MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
>Mature_46_residues
MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK

Specific function: Lanthionine-containing peptide antibiotic (lantibiotic) active on certain Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous tran

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type A lantibiotic family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SRTA_STRP1 (P0C0H9)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269245.1
- RefSeq:   YP_282169.1
- EnsemblBacteria:   EBSTRT00000000328
- EnsemblBacteria:   EBSTRT00000027500
- GeneID:   3572093
- GeneID:   901208
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1083
- KEGG:   spz:M5005_Spy_0806
- GeneTree:   EBGT00050000030252
- HOGENOM:   HBG219516
- ProtClustDB:   CLSK442868
- BioCyc:   SPYO160490:SPY1083-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0806-MONOMER
- GO:   GO:0019835
- InterPro:   IPR006079
- TIGRFAMs:   TIGR03731

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 5219; Mature: 5219

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
6.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
CCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEEEEECC
>Mature Secondary Structure
MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
CCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296