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The map label for this gene is aroF

Identifier: 15674852

GI number: 15674852

Start: 667276

End: 668442

Strand: Direct

Name: aroF

Synonym: SPy_0810

Alternate gene names: 15674852

Gene position: 667276-668442 (Clockwise)

Preceding gene: 15674851

Following gene: 15674853

Centisome position: 36.02

GC content: 42.16

Gene sequence:

>1167_bases
TTGCGTTATTTAACAGCAGGAGAATCTCATGGGCCATCCTTAACAGCTATTATTGAAGGTATACCAGCAGGATTAACTCT
TCATCCAGCGGATATTGATCACGAATTACAGCGACGTCAAGGAGGTTATGGCCGTGGTGCCAGAATGTCTATTGAGACTG
ATCGGGTTCAAATATCCTCAGGAGTTCGTCATGGTAAAACAACAGGGGCCCCCATTACCTTAACGGTAATTAATAAGGAC
CACCAAAAATGGCTAGATGTCATGGCTGTAGGAGACATTGAAGAGACTCTCAAGTTAAAGCGTCGTGTTAAGCATCCTAG
ACCAGGACATGCGGATTTGGTAGGAGGTATTAAATATCATTTTAACGATTTAAGAGATGCTTTAGAGCGTTCCTCGGCTA
GAGAAACAACGATGAGAGTGGCTGTAGGCGCTGTTGCTAAACGTATCTTAGCTGAACTTGGAATTGATATGTTACATCAT
ATCTTAATATTTGGTGGTATAACGATCACAATACCTTCTAAGCTCTCTTTTAGAGAGCTGCAAGAAAGGGCTCTCCATTC
AGAATTATCTATTGTTAATCCAAAGCAAGAAGAAGAAATTAAAACGTATATTGATAAGATAAAAAAAGAAGGGGATACCA
TTGGTGGTATTATCGAAACGATAGTTCAAGGGGTGCCAGCAGGTCTTGGATCTTATGTCCAATGGGATAAAAAATTAGAT
GCCAAGCTGGCTCAAGCAGTTCTTTCCATTAATGCTTTTAAAGGGGTGGAATTTGGAGCTGGGTTTGATATGGGATTCCA
AAAGGGCTCTCAGGTAATGGATGAAATCACCTGGACACCTACCCAGGGCTATGGTCGTCAAACAAACCACTTAGGTGGCT
TTGAAGGTGGCATGACCACAGGACAACCTCTTGTTGTTAAAGGGGTTATGAAGCCCATTCCTACTTTGTATAAACCACTC
ATGTCGGTAGATATTGATAGTCATGAACCTTATAAAGCAACGGTGGAACGCTCTGATCCGACGGCCTTACCAGCTGCAGG
GGTTATCATGGAAAATGTGGTGGCGACGGTGCTTGCCAAAGAGATTTTAGAGACTTTTTCTTCTACTACCATGTCTGAAT
TGCAAAAAGCTTTTTCGGACTATCGTGCCTACGTCAAGCAATTTTAG

Upstream 100 bases:

>100_bases
TAACTAGTGAATGGTCTAAAAATATTATTTCTACAATAGTTAAGAAATGATGTTTTTAGATTAATGTTTTTAAAATAAGT
GGAACCAAAAAGGAGAAAAA

Downstream 100 bases:

>100_bases
ATAGCGAGATACTGGCTTTTATGGTATCATACAGGTATTAATGAACAAAAGGAGACTGTCATGTCACAAGAAATTTATGA
CTATGCTAATCAACTTGAAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKD
HQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
AKLAQAVLSINAFKGVEFGAGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPL
MSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF

Sequences:

>Translated_388_residues
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKD
HQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
AKLAQAVLSINAFKGVEFGAGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPL
MSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF
>Mature_388_residues
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKD
HQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
AKLAQAVLSINAFKGVEFGAGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPL
MSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=38.1868131868132, Blast_Score=183, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6321290, Length=372, Percent_Identity=32.7956989247312, Blast_Score=157, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_STRP1 (Q9A0E4)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269026.1
- RefSeq:   YP_281988.1
- ProteinModelPortal:   Q9A0E4
- SMR:   Q9A0E4
- EnsemblBacteria:   EBSTRT00000000640
- EnsemblBacteria:   EBSTRT00000027920
- GeneID:   3572293
- GeneID:   900983
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0810
- KEGG:   spz:M5005_Spy_0625
- GeneTree:   EBGT00050000027669
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   SPYO160490:SPY0810-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0625-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42539; Mature: 42539

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISS
CCCCCCCCCCCCHHHHHHHCCCCCCEECCCCCCHHHHHHCCCCCCCCEEEEEHHHEEHHC
GVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYH
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHH
QERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AKLAQAVLSINAFKGVEFGAGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTT
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
EILETFSSTTMSELQKAFSDYRAYVKQF
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISS
CCCCCCCCCCCCHHHHHHHCCCCCCEECCCCCCHHHHHHCCCCCCCCEEEEEHHHEEHHC
GVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYH
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHH
QERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AKLAQAVLSINAFKGVEFGAGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTT
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
EILETFSSTTMSELQKAFSDYRAYVKQF
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296