Click here to switch to the map view.

The map label for this gene is endA [H]

Identifier: 15674813

GI number: 15674813

Start: 623186

End: 623668

Strand: Direct

Name: endA [H]

Synonym: SPy_0766

Alternate gene names: 15674813

Gene position: 623186-623668 (Clockwise)

Preceding gene: 15674812

Following gene: 161378151

Centisome position: 33.64

GC content: 43.27

Gene sequence:

>483_bases
ATGCCTTACTTACTAAGTCGACACGACAGTATCGAAATCGCTATCAAACGGATAATGCTTATCGTAACTTTAAGCCCAGC
AGGTTGGCACCGATTGCACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAG
TTGGTGGACTGAAAGGTTTTGATGCTTCTACTGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCA
AATAAACCCTACTTGACAGGTCAGAATTACTATGAAGGTTTAGTACGTCGTGCTTTAGATAAGGGGCATCGCGTCCGCTA
CCGTGTCACCCTACTTTATGATGGTGATAATCTACTAGCCAGCGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCT
TGACTTTTAACGTGTTTGTTCCAAATGTCCAAGCAGGATTGACCGCTGACTATCGGACGGGACAAATAGCTATCAATCTC
TAA

Upstream 100 bases:

>100_bases
AAAGTAGGCCTTGCCTACTTTTTATAGCATCTGAGAGGAAGTATGTTAACAAGGAAAAAACGAAAAAGGGTGCAAGAGCA
AAAGGTTCCTAAAAGAGCTA

Downstream 100 bases:

>100_bases
GCGAAAAGTCACTGATTTAAGATTGTCACTAAGCACTTTTTTTGATAGAATAGAACTAATTGAATAAGTGTCTATGAGAC
TAGTACTAATAGAGAAATTA

Product: putative competence associated membrane nuclease

Products: NA

Alternate protein names: Competence-specific nuclease [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MPYLLSRHDSIEIAIKRIMLIVTLSPAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQA
NKPYLTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQAGLTADYRTGQIAINL

Sequences:

>Translated_160_residues
MPYLLSRHDSIEIAIKRIMLIVTLSPAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQA
NKPYLTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQAGLTADYRTGQIAINL
>Mature_159_residues
PYLLSRHDSIEIAIKRIMLIVTLSPAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQAN
KPYLTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQAGLTADYRTGQIAINL

Specific function: By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: NA

Molecular weight: Translated: 17702; Mature: 17571

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYLLSRHDSIEIAIKRIMLIVTLSPAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGF
CCCCCCCCCCHHHHEEEEEEEEEECCCCHHHHHHCCCCCCHHCCCCHHHEEHHHCCCCCC
DASTGNPDNIATQLSWANQANKPYLTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLA
CCCCCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEE
SGSHLEAKSSDDSLTFNVFVPNVQAGLTADYRTGQIAINL
CCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCEEEEEC
>Mature Secondary Structure 
PYLLSRHDSIEIAIKRIMLIVTLSPAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGF
CCCCCCCCCHHHHEEEEEEEEEECCCCHHHHHHCCCCCCHHCCCCHHHEEHHHCCCCCC
DASTGNPDNIATQLSWANQANKPYLTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLA
CCCCCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEE
SGSHLEAKSSDDSLTFNVFVPNVQAGLTADYRTGQIAINL
CCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2359120; 11463916 [H]