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The map label for this gene is adcA

Identifier: 15674772

GI number: 15674772

Start: 572039

End: 573586

Strand: Direct

Name: adcA

Synonym: SPy_0714

Alternate gene names: 15674772

Gene position: 572039-573586 (Clockwise)

Preceding gene: 15674771

Following gene: 15674773

Centisome position: 30.88

GC content: 38.95

Gene sequence:

>1548_bases
ATGAAAAAGAAAATTCTTTTAATGATGAGTTTAATCAGTGTCTTTTTTGCTTGGCAACTTACTCAGGCAAAACAAGTCTT
AGCAGAGGGTAAAGTGAAGGTGGTGACAACTTTCTATCCTGTTTATGAATTTACAAAAGGGGTTATTGGTAATGATGGCG
ATGTTTTCATGCTTATGAAAGCAGGAACGGAACCTCATGATTTTGAGCCTTCTACAAAAGACATTAAAAAAATCCAAGAT
GCAGATGCATTTGTTTATATGGATGACAATATGGAAACTTGGGTTTCTGATGTGAAAAAATCATTGACATCTAAAAAAGT
GACCATCGTCAAGGGAACTGGTAACATGCTCTTGGTAGCAGGAGCTGGACATGACCATCCCCATGAGGATGCTGACAAAA
AGCATGAGCATAATAAACATAGCGAAGAAGGACACAACCATGCTTTTGACCCACACGTGTGGTTGTCACCATACCGTAGC
ATTACAGTCGTTGAAAATATTCGCGACAGTCTTTCAAAAGCTTACCCAGAAAAAGCAGAGAACTTCAAAGCCAATGCCGC
TACTTATATTGAAAAATTAAAAGAGCTTGACAAAGACTATACGGCAGCACTTTCAGATGCTAAGCAAAAGAGCTTTGTGA
CACAACACGCAGCTTTTGGTTATATGGCACTTGACTATGGCTTGAACCAAATTTCTATTAATGGTGTCACACCAGATGCA
GAACCATCAGCAAAACGTATTGCTACTTTGTCAAAATACGTTAAAAAATATGGCATCAAATACATTTATTTTGAGGAAAA
TGCGTCAAGTAAAGTCGCAAAAACCCTAGCTAAAGAAGCAGGAGTTAAAGCGGCTGTGCTTAGTCCGCTTGAAGGTTTGA
CTGAAAAAGAGATGAAAGCTGGCCAAGATTACTTTACGGTCATGCGTAAAAACCTTGAAACCTTACGCTTAACCACTGAT
GTGGCTGGTAAAGAAATTCTTCCAGAAAAAGACACGACTAAGACAGTTTACAATGGTTATTTCAAAGACAAAGAAGTCAA
AGATCGTCAATTATCTGACTGGTCAGGTAGCTGGCAATCTGTTTACCCCTATCTACAAGATGGTACTTTAGACCAAGTTT
GGGACTACAAGGCTAAAAAATCTAAAGGTAAAATGACAGCAGCCGAGTACAAAGATTACTACACTACTGGTTATAAAACT
GACGTGGAACAAATCAAAATCAATGGTAAGAAAAAGACCATGACCTTTGTTCGTAATGGTGAAAAGAAAACCTTCACTTA
CACATACGCCGGCAAAGAAATCTTGACCTATCCAAAAGGAAATCGCGGGGTTCGTTTCATGTTTGAAGCTAAAGAAGCAG
ATGCTGGCGAATTCAAATACGTTCAATTCAGTGACCATGCCATTGCTCCTGAAAAAGCAAAGCATTTCCACCTGTACTGG
GGTGGTGACAGCCAAGAAAAATTACATAAAGAGTTAGAACATTGGCCAACTTACTACGGTTCAGACTTATCTGGTCGTGA
AATCGCCCAAGAAATCAATGCTCATTAA

Upstream 100 bases:

>100_bases
AGGAAAAGTAATCGCAAAAAGACAAAAACTTGGAAAAAAAATCAAAGTATGCTATACTTAACTGGTCAATTTTTAACCAG
TTAATAACAAAGGAGGAATC

Downstream 100 bases:

>100_bases
TCTTAACTCACTAAGCAAATCTTCTTTTAAGGAGGTTTGCTTTTTCTTTGTGGAGTAAAAAAATTTAATAATTCTCAACA
TTAATTTGACGGACACTTAT

Product: putative adhesion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMKAGTEPHDFEPSTKDIKKIQD
ADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGAGHDHPHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTD
VAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKT
DVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH

Sequences:

>Translated_515_residues
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMKAGTEPHDFEPSTKDIKKIQD
ADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGAGHDHPHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTD
VAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKT
DVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
>Mature_515_residues
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMKAGTEPHDFEPSTKDIKKIQD
ADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGAGHDHPHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTD
VAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKT
DVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH

Specific function: Part of the ATP-driven transport system AdcABC for zinc

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family

Homologues:

Organism=Escherichia coli, GI1788284, Length=188, Percent_Identity=48.4042553191489, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI87081990, Length=261, Percent_Identity=24.904214559387, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADCA_STRP1 (Q9A0L9)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268946.1
- RefSeq:   YP_281906.1
- ProteinModelPortal:   Q9A0L9
- EnsemblBacteria:   EBSTRT00000000324
- EnsemblBacteria:   EBSTRT00000028613
- GeneID:   3572365
- GeneID:   900899
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0714
- KEGG:   spz:M5005_Spy_0543
- GeneTree:   EBGT00050000027213
- HOGENOM:   HBG731008
- OMA:   QALDKAY
- ProtClustDB:   CLSK877084
- BioCyc:   SPYO160490:SPY0714-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0543-MONOMER
- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304
- Gene3D:   G3DSA:2.40.128.20
- PRINTS:   PR00691
- PRINTS:   PR00690

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA; SSF50814 Calycin

EC number: NA

Molecular weight: Translated: 58521; Mature: 58521

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCCCCCCCEEEEEE
AGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVA
CCCCCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
GAGHDHPHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRSITVVENIRDSLSKAYPEKAE
ECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCHHHH
NFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEECCCCCCC
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKA
CCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHC
GQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQS
CHHHHHHHHHCHHHEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
VYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKTDVEQIKINGKKKTMTFVRNG
HCCCCCCCCHHHHHCCHHHHCCCCEEHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECC
EKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
CCEEEEEEECCCEEEECCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEE
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCCCCCCCEEEEEE
AGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVA
CCCCCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
GAGHDHPHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRSITVVENIRDSLSKAYPEKAE
ECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCHHHH
NFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEECCCCCCC
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKA
CCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHC
GQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQS
CHHHHHHHHHCHHHEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
VYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKTDVEQIKINGKKKTMTFVRNG
HCCCCCCCCHHHHHCCHHHHCCCCEEHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECC
EKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
CCEEEEEEECCCEEEECCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEE
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296