Definition Streptococcus pyogenes M1 GAS chromosome, complete genome.
Accession NC_002737
Length 1,852,441

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The map label for this gene is yhbA [H]

Identifier: 15674712

GI number: 15674712

Start: 514849

End: 516024

Strand: Direct

Name: yhbA [H]

Synonym: SPy_0642

Alternate gene names: 15674712

Gene position: 514849-516024 (Clockwise)

Preceding gene: 15674711

Following gene: 15674713

Centisome position: 27.79

GC content: 36.31

Gene sequence:

>1176_bases
TTGTCCTTCTTTTTCCTTGAAGTCTTAACTTATTTTGATTATGATAGTAGTATGACTATTAAGGCAGAAATTAAGGCGCT
CGCCAAAGAAATTGGTATCTCTAAAATTGGTTTTACGACGGCAGATAACTTTGATTATTTGGAAAAGTCATTGCGTGCTT
CTGTGGAAGAGGGGCGCAATTCAGGATTTGAACATAAAGTCATAGAGGATCGTATCTACACTGAAAGGCTTTTAGAATCG
GCTAAAACGATTATTTCAATTGGCGTTGCTTATCCTCACAAACTTCCTCAGCAACCTCAAAAAACACCTTATAAACGTGG
AAAAATTACACCTAGTTCGTGGGGGCTTGATTATCATTATGTGGTCGGCGAAAAGTTAGACAGACTATCAAAAGGCATTG
AAGAGCTGTGTCGAGATTTTCCTTTGCAACAAAAAGCAATGGTCGATACTGGAGCTTTAGTTGATACTGCAGTTGCCCAA
AGAGCGGGTATTGGTTTTATAGGAAAAAATGGTCTAGTTATTTCTAAAGAATATGGCTCTTATATGTTTTTGGGAGAATT
AATTACCAATTTAGAGATCGAGCCAGACAAGCCTGTCGATTATGATTGTGGTGACTGTCGTCGTTGTCTAGATGCCTGTC
CAACTTCTTGTTTAATTGGTGATGGCTCAATGAATGCCAAGCGTTGTCTATCATTTCAAACCCAAGATAAGGGAATGATG
GACATAGAGTTTCGAAAAAAGATTAAAACAGTTATCTATGGTTGTGATATTTGCCAAATTTGCTGTCCTTATAACAAGGG
TATAAACAATTCACCAGCTACAGAGATTGATCCTGAGTTGGCTCAACCAGAATTAATACCATTTTTGAGTTTATCAAATG
GAAAATTTAAAGAAAAATTTGGTATGATTGCTGGAAGTTGGCGAGGTAAAAATATTTTACAGCGTAATGCCATTATTGCG
CTAGCAAATGCTCATGATAAAACTGCAGTGGTCAAATTAATAGAGATTATTGATAAAAATAATAACCCTATTCATACTGC
AACAGCTATATGGGCATTGGGAGAAATTGTCAAAAAACCAAACGATGAGATACTGGCGTTTATGAGTCATTTAACCTTAA
AAGATGAAGATAGCCGAAAAGAGTTGGAATTAATCCGTCATAAATGGCAATTTTAA

Upstream 100 bases:

>100_bases
ACTTTTACGATGGAATTGAATTTACTTGTTGCATTCTTGTGCATGTTAAGAGAGAAAACCCAGATAAATCAGGAAGTAAA
ATGGTTATGTTTGATTAGAA

Downstream 100 bases:

>100_bases
GCCTTTTATGGTATTTTTAAGAACCTTATGATAAAATAAAACAGATTAACAAAGATTGGAGAAATCTCATGGAAGTGGCT
GAAATTCGCCAAAAAATAGT

Product: iron-sulfur cluster-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSFFFLEVLTYFDYDSSMTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNSGFEHKVIEDRIYTERLLES
AKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYHYVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQ
RAGIGFIGKNGLVISKEYGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQDKGMM
DIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSNGKFKEKFGMIAGSWRGKNILQRNAIIA
LANAHDKTAVVKLIEIIDKNNNPIHTATAIWALGEIVKKPNDEILAFMSHLTLKDEDSRKELELIRHKWQF

Sequences:

>Translated_391_residues
MSFFFLEVLTYFDYDSSMTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNSGFEHKVIEDRIYTERLLES
AKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYHYVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQ
RAGIGFIGKNGLVISKEYGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQDKGMM
DIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSNGKFKEKFGMIAGSWRGKNILQRNAIIA
LANAHDKTAVVKLIEIIDKNNNPIHTATAIWALGEIVKKPNDEILAFMSHLTLKDEDSRKELELIRHKWQF
>Mature_390_residues
SFFFLEVLTYFDYDSSMTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNSGFEHKVIEDRIYTERLLESA
KTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYHYVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQR
AGIGFIGKNGLVISKEYGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQDKGMMD
IEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSNGKFKEKFGMIAGSWRGKNILQRNAIIAL
ANAHDKTAVVKLIEIIDKNNNPIHTATAIWALGEIVKKPNDEILAFMSHLTLKDEDSRKELELIRHKWQF

Specific function: Unknown

COG id: COG1600

COG function: function code C; Uncharacterized Fe-S protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HEAT-like PBS-type repeats [H]

Homologues:

Organism=Escherichia coli, GI1790608, Length=354, Percent_Identity=28.2485875706215, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004453
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR011989
- InterPro:   IPR016024
- InterPro:   IPR013542
- InterPro:   IPR009051
- InterPro:   IPR004155 [H]

Pfam domain/function: PF08331 DUF1730; PF03130 HEAT_PBS [H]

EC number: NA

Molecular weight: Translated: 44003; Mature: 43872

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFFLEVLTYFDYDSSMTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRN
CCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHCC
SGFEHKVIEDRIYTERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYHY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
VVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKEYGS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHCCCCEECCCCEEEEECCCC
YMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQDKGMM
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCCCCCE
DIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSNGKFKEKF
EHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHH
GMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIWALGEIVKKP
CCCCCCCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
NDEILAFMSHLTLKDEDSRKELELIRHKWQF
CHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFFFLEVLTYFDYDSSMTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRN
CHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHCC
SGFEHKVIEDRIYTERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYHY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
VVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKEYGS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHCCCCEECCCCEEEEECCCC
YMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQDKGMM
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCCCCCE
DIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSNGKFKEKF
EHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHH
GMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIWALGEIVKKP
CCCCCCCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
NDEILAFMSHLTLKDEDSRKELELIRHKWQF
CHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]