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The map label for this gene is yabD [H]

Identifier: 15674440

GI number: 15674440

Start: 224791

End: 225615

Strand: Direct

Name: yabD [H]

Synonym: SPy_0260

Alternate gene names: 15674440

Gene position: 224791-225615 (Clockwise)

Preceding gene: 15674438

Following gene: 15674441

Centisome position: 12.13

GC content: 42.55

Gene sequence:

>825_bases
ATGTGGTTAAGATCTTTATGTTATAATAACATCATGACAAATAAAGTAGAAAAACTAACTATTTTTGATACCCATACGCA
CCTGAATGTAGCAGAATTTCAAGGACACGAAACTGAAGAATTGACTTTGGCTCAAGAAATGGGCGTGGCCTACCATAATG
TGGTTGGCTTTGACCAGGCCACTATTAGTGGGGCACTAACTCTAGCCAATAAATATGCCAATATTTATGCAACTATTGGG
TGGCATCCAACAGAAGCAGGTTCTTATTCAGAGGCTGTTGAGGAGGCTATCGTCTCTCAATTATCACATTCCAAAGTGAT
TGCCTTAGGTGAAATTGGCTTAGACTATTATTGGATGGAGGACCCCAAAGAGGTGCAAATAGAGGTTTTTAAGCGCCAAA
TGCAATTAGCAAAAGACCATGATTTGCCTTTTGTGGTGCACACCCGCGATGCCTTGGAAGATACCTATGAGGTCATCAAA
GCAGCTGGTGTTGGCCCTCGTGGAGGCATCATGCATTCTTACTCAGGGTCATTAGAGATGGCTGAACGTTTCATTGAACT
TGGCATGATGATTTCCTTTTCAGGTGTGGTCACTTTCAAAAAGGCTCTTGATATTCAAGAGGCAGCGCAGCACTTGCCTT
TGGATAAGATTTTGGTGGAAACAGATGCCCCTTATCTTACACCAGTTCCAAAACGTGGCAAACAAAATCATACAGCTTAT
ACCCGCTATGTGGTTGATAAAATCGCAGAGCTACGGGGGATGACTGTGGAAGAAGTTGCAAAAGCAACGACTGCTAATGC
AAAGAGGGTATTCAAGCTTGACTGA

Upstream 100 bases:

>100_bases
TTAAAGGTCATTTGTCAAAAAAGTAGAAAATAGACAAGTGTCAGCTAGCAAAGGGTTTTACGATCAACCTAAACGGCAGA
AGTTCTCACCAAGTTTTCTG

Downstream 100 bases:

>100_bases
AAAAATTAATATTCAAGAGGTTCTTGTTGTAGAAGGCAAGGACGACACGGCTAACCTACGCCGTTTTTACGAGGTGGATA
CCTATGAGACTAGAGGCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVVGFDQATISGALTLANKYANIYATIG
WHPTEAGSYSEAVEEAIVSQLSHSKVIALGEIGLDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIK
AAGVGPRGGIMHSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPVPKRGKQNHTAY
TRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD

Sequences:

>Translated_274_residues
MWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVVGFDQATISGALTLANKYANIYATIG
WHPTEAGSYSEAVEEAIVSQLSHSKVIALGEIGLDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIK
AAGVGPRGGIMHSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPVPKRGKQNHTAY
TRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD
>Mature_274_residues
MWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVVGFDQATISGALTLANKYANIYATIG
WHPTEAGSYSEAVEEAIVSQLSHSKVIALGEIGLDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIK
AAGVGPRGGIMHSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPVPKRGKQNHTAY
TRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=206, Percent_Identity=35.9223300970874, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI14042943, Length=190, Percent_Identity=29.4736842105263, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI225903439, Length=169, Percent_Identity=30.1775147928994, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=26.4150943396226, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=26.4150943396226, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=26.2962962962963, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI226061614, Length=256, Percent_Identity=25.390625, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=25.5506607929515, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=36.046511627907, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=33.203125, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=29.0697674418605, Blast_Score=126, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=28.1138790035587, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=268, Percent_Identity=26.4925373134328, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=215, Percent_Identity=30.6976744186047, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=222, Percent_Identity=29.2792792792793, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586117, Length=188, Percent_Identity=33.5106382978723, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221330018, Length=188, Percent_Identity=33.5106382978723, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24648690, Length=295, Percent_Identity=26.7796610169492, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30697; Mature: 30697

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVVGFDQA
CCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHCCHHHHHCCCCHH
TISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVSQLSHSKVIALGEIGLDYYWME
HHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEECC
DPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIMHSYSGSLEM
CCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPVPKRGKQNHTAY
HHHHHHHHHHEEECHHHHHHHHHCHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHH
TRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD
HHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVVGFDQA
CCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHCCHHHHHCCCCHH
TISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVSQLSHSKVIALGEIGLDYYWME
HHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEECC
DPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIMHSYSGSLEM
CCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPVPKRGKQNHTAY
HHHHHHHHHHEEECHHHHHHHHHCHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHH
TRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD
HHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]