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The map label for this gene is yfnA [H]

Identifier: 15674262

GI number: 15674262

Start: 15110

End: 16501

Strand: Direct

Name: yfnA [H]

Synonym: SPy_0016

Alternate gene names: 15674262

Gene position: 15110-16501 (Clockwise)

Preceding gene: 15674261

Following gene: 15674263

Centisome position: 0.82

GC content: 33.12

Gene sequence:

>1392_bases
ATGACTATTTTTCGTAAAAAAAAGAAATATTCCAATAAAACAGAAATGCAAAGGCACTTCAAAGTTATTGATTTAGTTTT
TTTAGGCCTAGGTTCAATGGTTGGAACAGGTATCTTTACAGTTACTGGCATAGGCGCTGCTAAGTATGCAGGTCCTGCTT
TAACAATATCGATTATCATTTCCGCGATTGCTATTGGAATTTTAGCCTTATTTTATGCAGAATTTGCGTCTCGTATGCCT
TCTAACGGTGGTGCTTATAGTTATGTTTATGCAACCTTGGGAGAGTTTCCAGCATGGCTTGTTGGCTGGTATATTATTAT
GGAATTTTTAACAGCTATATCTAGTGTTGCTGTTGGCTGGGGAAGTTATTTAAAAGGATTACTTGCCAATTATAATATAG
TATTACCAAACGCTTTAAATGGCACGTTCAATCTTAAGAATGGAACTTACATAGATATTCTTCCTGTTTTAGTGATGTTT
TTCGTGACAGGGATTGTCCTAATGAATTCGAAATTAGCCCTGAGATTCAATAGTTTTTTAGTTATTTTAAAATTTTCAGC
ACTGGCTTTATTTATCTTTGTAGGCATTTTTTTTATTGATCACAATAATTGGTCTCATTTTGCTCCATATGGTGTAGGAC
AAATTACTGGAGGTAAAACAGGTATCTTTGCTGGTGCTTCTGTTATGTTCTTTGCATTTTTAGGATTTGAATCTATTTCA
ATGGCAGTTGATGAAGTGAAAGAACCACAAAAAACAATCCCTAAAGGCATCATTTTATCTTTGATTATTGTAACAGCACT
CTATATAGTTGTCACCACTATTTTAACGGGAATTGTACACTACACTAAATTAAATGTTCCAGACGCGGTGGCTTTTGCTT
TAAGAAATATTAGACTTTATTGGGCAGCTGACTATGTGTCGATAGTTGCTATTTTGACTCTTATTACGGTATGTATTTCT
ATGACCTATGCATTAGCTAGAACAATTTACAGTATTAGTAGAGATGGTTTATTACCTAAATCACTTTATACTCTCACTAA
AAAAAATAAAGTGCCTCAAAATGCTACTCTTGTCACTGGACTACTTGCTATGATTTGTGCGGGAATATTTCCTTTATCGA
GTCTAGCAGAGTTTGTTAATATTTGTACTTTAGCATATTTAATTATTCTGTCGGGTGCAATTATTAAACTCAGAAGAATA
GAAGGAGAACCAAAAGCAAATGAATTTAAAACTCCTCTAGTACCATTCCTACCAATGTTGGCAATTATCATTTGTCTATC
ATTTATGAGCCAATATAAAGCTTTTACTTGGATTGCTTTTGCTATTGCCACAATTATTGGAACATTAATCTACTTAGCTT
ATGGTTATACTCATTCAATAGAAAATAAATAA

Upstream 100 bases:

>100_bases
AAGATAGCAAAAGTTTCAGTCAACCAATAAGATGAAATTTACAATCATTACTAACTATGATACACTTAGTAGAAAATCAT
TTACTATAGAAGGTGATAAC

Downstream 100 bases:

>100_bases
TGTTTTGATAATAAGATTTGACATTACATTATAGACTATAACGTTTAGAAGTAAATGAGTAGTAAAATCAATACCTACTT
ACTTATCAAAGTTGTAATAT

Product: putative amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGIGAAKYAGPALTISIIISAIAIGILALFYAEFASRMP
SNGGAYSYVYATLGEFPAWLVGWYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGGKTGIFAGASVMFFAFLGFESIS
MAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILTGIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCIS
MTYALARTIYSISRDGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSGAIIKLRRI
EGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLIYLAYGYTHSIENK

Sequences:

>Translated_463_residues
MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGIGAAKYAGPALTISIIISAIAIGILALFYAEFASRMP
SNGGAYSYVYATLGEFPAWLVGWYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGGKTGIFAGASVMFFAFLGFESIS
MAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILTGIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCIS
MTYALARTIYSISRDGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSGAIIKLRRI
EGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLIYLAYGYTHSIENK
>Mature_462_residues
TIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGIGAAKYAGPALTISIIISAIAIGILALFYAEFASRMPS
NGGAYSYVYATLGEFPAWLVGWYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMFF
VTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGGKTGIFAGASVMFFAFLGFESISM
AVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILTGIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISM
TYALARTIYSISRDGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSGAIIKLRRIE
GEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLIYLAYGYTHSIENK

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=392, Percent_Identity=33.1632653061224, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI110347453, Length=399, Percent_Identity=29.5739348370927, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI4507047, Length=430, Percent_Identity=28.6046511627907, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI258614005, Length=430, Percent_Identity=29.3023255813954, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI258614003, Length=430, Percent_Identity=29.3023255813954, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI114326544, Length=432, Percent_Identity=28.7037037037037, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI114326550, Length=432, Percent_Identity=28.7037037037037, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI258645169, Length=430, Percent_Identity=28.6046511627907, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7657683, Length=381, Percent_Identity=26.246719160105, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI187423910, Length=427, Percent_Identity=21.5456674473068, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI7657591, Length=427, Percent_Identity=21.5456674473068, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI115648063, Length=374, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI115648022, Length=374, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082250, Length=423, Percent_Identity=25.531914893617, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081708, Length=447, Percent_Identity=22.5950782997763, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082023, Length=373, Percent_Identity=24.3967828418231, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788480, Length=472, Percent_Identity=21.3983050847458, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786302, Length=450, Percent_Identity=23.1111111111111, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786602, Length=425, Percent_Identity=22.5882352941176, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081869, Length=393, Percent_Identity=21.882951653944, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=482, Percent_Identity=32.7800829875519, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17531343, Length=474, Percent_Identity=32.2784810126582, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17533459, Length=414, Percent_Identity=32.1256038647343, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71982612, Length=445, Percent_Identity=24.0449438202247, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71982608, Length=445, Percent_Identity=24.0449438202247, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540018, Length=430, Percent_Identity=25.1162790697674, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=312, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193208714, Length=258, Percent_Identity=22.8682170542636, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32566695, Length=258, Percent_Identity=22.8682170542636, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17537453, Length=379, Percent_Identity=21.6358839050132, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17568033, Length=429, Percent_Identity=24.7086247086247, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24667468, Length=417, Percent_Identity=33.0935251798561, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24666159, Length=439, Percent_Identity=32.5740318906606, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI221512776, Length=439, Percent_Identity=32.5740318906606, Blast_Score=207, Evalue=9e-54,
Organism=Drosophila melanogaster, GI24668806, Length=412, Percent_Identity=32.7669902912621, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21356285, Length=412, Percent_Identity=32.7669902912621, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24668802, Length=412, Percent_Identity=32.7669902912621, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI161077963, Length=415, Percent_Identity=31.8072289156626, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281366235, Length=429, Percent_Identity=30.7692307692308, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI116007820, Length=429, Percent_Identity=30.7692307692308, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI116007818, Length=417, Percent_Identity=31.1750599520384, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI85725152, Length=417, Percent_Identity=31.1750599520384, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21357367, Length=428, Percent_Identity=20.0934579439252, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221331183, Length=335, Percent_Identity=22.089552238806, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647653, Length=335, Percent_Identity=22.089552238806, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24664379, Length=335, Percent_Identity=22.089552238806, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550968, Length=361, Percent_Identity=21.606648199446, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921172, Length=361, Percent_Identity=21.606648199446, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50747; Mature: 50616

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGIGAAKYAGPALTISIII
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCHHHHHHHH
SAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVGWYIIMEFLTAISSVAVGW
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMFFVTGIVLMNSKLALRFNSFL
HHHHHHHHHCCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGGKTGIFAGASVMFFAFLGFESIS
HHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
MAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILTGIVHYTKLNVPDAVAFALRNIRLY
HHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHE
WAADYVSIVAILTLITVCISMTYALARTIYSISRDGLLPKSLYTLTKKNKVPQNATLVTG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHH
LLAMICAGIFPLSSLAEFVNICTLAYLIILSGAIIKLRRIEGEPKANEFKTPLVPFLPML
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
AIIICLSFMSQYKAFTWIAFAIATIIGTLIYLAYGYTHSIENK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
>Mature Secondary Structure 
TIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGIGAAKYAGPALTISIII
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCHHHHHHHH
SAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVGWYIIMEFLTAISSVAVGW
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMFFVTGIVLMNSKLALRFNSFL
HHHHHHHHHCCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGGKTGIFAGASVMFFAFLGFESIS
HHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
MAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILTGIVHYTKLNVPDAVAFALRNIRLY
HHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHE
WAADYVSIVAILTLITVCISMTYALARTIYSISRDGLLPKSLYTLTKKNKVPQNATLVTG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHH
LLAMICAGIFPLSSLAEFVNICTLAYLIILSGAIIKLRRIEGEPKANEFKTPLVPFLPML
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
AIIICLSFMSQYKAFTWIAFAIATIIGTLIYLAYGYTHSIENK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]