| Definition | Streptococcus pyogenes M1 GAS chromosome, complete genome. |
|---|---|
| Accession | NC_002737 |
| Length | 1,852,441 |
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The map label for this gene is ftsH [H]
Identifier: 15674261
GI number: 15674261
Start: 12806
End: 14785
Strand: Direct
Name: ftsH [H]
Synonym: SPy_0015
Alternate gene names: 15674261
Gene position: 12806-14785 (Clockwise)
Preceding gene: 15674260
Following gene: 15674262
Centisome position: 0.69
GC content: 37.68
Gene sequence:
>1980_bases ATGAAAAATAATAAAAATAATGGTTTTGTTAAAAATTCTTTTATATATATATTGATGATTATTGTTGTCATCACAGGATT TCAATTTTATCTTAAGGGAACCAGCACACAAAGCCAACAGATTAGTTATTCCAAATTAATTAAACATCTTAAGGCTGGAG ATATAAAATCTTTAAGTTATCAGCCTAGCGGTAGTATTATTGAAGTTAAAGGGAAATATGAGAAACCTCAAAAAGTGACA GTTAATTCAGGACTATCATTTTTAGGTGGAAGAGCTTCAACACAGGTAACAGAGTTCTCATCTTTAGTATTACCTAGTGA TACCATCTTGAAAGAAATGACAGCAGCAGCTGATAAAAATGGAACAGAGCTTACAGTTAAGCAGGAAAGTTCAAGTGGTA CTTGGATTACCTTCTTAATGAGCTTTTTACCTATTGTTATTTTTGCTGCTTTCATGATGATGATGATGAATCAAGGTGGT GGAGGAGCTCGTGGTGCTATGAGTTTCGGCAAAAATAAGGCAAAATCTCAATCAAAAGGTAATGTTAAAGTGAGATTTAC AGACGTTGCTGGTGCCGAAGAAGAAAAACAAGAATTAGTAGAAGTTGTTGATTTTTTGAAAAATCCTAAAAAATATAAAT CACTAGGAGCACGGATTCCAGCGGGAGTTCTTCTAGAGGGGCCTCCAGGTACTGGTAAAACATTACTAGCTAAAGCTGTA GCAGGTGAAGCTGGAGTGCCATTTTTCAGTATTTCAGGTTCGGATTTTGTCGAAATGTTTGTCGGTGTAGGTGCTAGTCG TGTTCGTTCTTTATTTGAGGATGCTAAAAAAGCTGAGCGTGCGATCATCTTTATCGATGAAATTGACGCTGTAGGTCGTC GTCGTGGTGCTGGCATGGGAGGCGGTAACGATGAACGAGAACAGACCCTTAACCAATTACTCATTGAAATGGATGGTTTT GAGGGTAATGAGAACATTATCGTTATTGCTGCAACTAACCGTAGTGATGTTTTAGATCCAGCTTTACTAAGACCAGGTCG TTTTGATCGTAAGGTTTTAGTTGGTCGCCCTGATGTTAAAGGACGTGAAGCCATTTTACGTGTTCATGCTAAAAATAAAC CACTTGCAAATGACGTTAATTTGAAAGTAGTAGCCCAACAGACTCCAGGTTTTGTAGGTGCTGATCTTGAAAATGTTTTA AATGAAGCTGCGTTGGTTGCTGCTCGCAGAAATAAAATTAAAATTGATGCTAGTGATATTGATGAAGCTGAAGATCGTGT TATTGCTGGACCATCAAAGAAAGATCGCACTATTTCGCAAAAAGAGCGAGAAATGGTTGCTTATCACGAAGCTGGTCATA CTATTGTTGGTTTAGTTTTATCTAATGCGCGTGTAGTTCACAAGGTAACTATTGTACCTCGTGGACGAGCAGGTGGTTAT ATGATCGCTCTTCCAAAAGAAGATCAAATGCTTCTTTCTAAAGAAGATCTGAAAGAGCAATTAGCAGGATTGATGGGTGG TCGTGTTGCTGAAGAAATTGTTTTTAATGCTCAAACATCAGGTGCGTCAAATGACTTTGAGCAAGCTACTCAGATAGCAA GGGCCATGGTTACGGAATATGGTATGAGTGAAAAGCTTGGACCAGTTCAATATGAAGGTAACCATGCGATGATGCCAGGA CAGATCTCTCCTGAAAAAGCTTACTCTGCCCAAACAGCTCAAATGATTGATGATGAGGTTCGTGAACTCTTAAATCAAGC TCGTAATCAAGCAGCTGATATCATCAATGAGAATCGAGATACTCATAAATTGATTGCTGAAGCTCTTCTCAAATATGAAA CTCTAGACGCTGCACAAATTAAATCAATTTATGAAACTGGTAAAATGCCAGTTGATTTAGAAACTGATGATAATGAAGCT CATGCGTTATCTTATGACGAAATTAAAAATAAAATGACAGAATCTGAATCTGCAGAATGA
Upstream 100 bases:
>100_bases CTTTGGTTTAGATTACGCAGAAAATTATCGCAATCTTCCTTACGTAGGTGTATTAAAAGAAGAAGTCTATTCAAAATAGA AAAAGGTCAATGTTTACTGT
Downstream 100 bases:
>100_bases TATAAAAAAGCTGAACTTATAGATTAAGTTCAGCTTTTTTATCAACACAATATCCTTGTAAACGTTATGAATTGTAATAG GTGCCTAATTGCTAGAAATG
Product: putative cell division protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 659; Mature: 659
Protein sequence:
>659_residues MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYSKLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVT VNSGLSFLGGRASTQVTEFSSLVLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG GGARGAMSFGKNKAKSQSKGNVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGARIPAGVLLEGPPGTGKTLLAKAV AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGF EGNENIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFVGADLENVL NEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY MIALPKEDQMLLSKEDLKEQLAGLMGGRVAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPG QISPEKAYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIYETGKMPVDLETDDNEA HALSYDEIKNKMTESESAE
Sequences:
>Translated_659_residues MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYSKLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVT VNSGLSFLGGRASTQVTEFSSLVLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG GGARGAMSFGKNKAKSQSKGNVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGARIPAGVLLEGPPGTGKTLLAKAV AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGF EGNENIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFVGADLENVL NEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY MIALPKEDQMLLSKEDLKEQLAGLMGGRVAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPG QISPEKAYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIYETGKMPVDLETDDNEA HALSYDEIKNKMTESESAE >Mature_659_residues MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYSKLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVT VNSGLSFLGGRASTQVTEFSSLVLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG GGARGAMSFGKNKAKSQSKGNVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGARIPAGVLLEGPPGTGKTLLAKAV AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGF EGNENIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFVGADLENVL NEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY MIALPKEDQMLLSKEDLKEQLAGLMGGRVAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPG QISPEKAYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIYETGKMPVDLETDDNEA HALSYDEIKNKMTESESAE
Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]
COG id: COG0465
COG function: function code O; ATP-dependent Zn proteases
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]
Homologues:
Organism=Homo sapiens, GI300192933, Length=495, Percent_Identity=48.8888888888889, Blast_Score=462, Evalue=1e-130, Organism=Homo sapiens, GI21327685, Length=450, Percent_Identity=47.3333333333333, Blast_Score=400, Evalue=1e-111, Organism=Homo sapiens, GI7657689, Length=450, Percent_Identity=47.3333333333333, Blast_Score=399, Evalue=1e-111, Organism=Homo sapiens, GI4507173, Length=445, Percent_Identity=44.0449438202247, Blast_Score=374, Evalue=1e-103, Organism=Homo sapiens, GI24497435, Length=253, Percent_Identity=41.897233201581, Blast_Score=206, Evalue=7e-53, Organism=Homo sapiens, GI4506209, Length=252, Percent_Identity=42.8571428571429, Blast_Score=202, Evalue=1e-51, Organism=Homo sapiens, GI45643125, Length=281, Percent_Identity=38.7900355871886, Blast_Score=197, Evalue=3e-50, Organism=Homo sapiens, GI45643123, Length=281, Percent_Identity=38.7900355871886, Blast_Score=197, Evalue=3e-50, Organism=Homo sapiens, GI6005942, Length=238, Percent_Identity=44.9579831932773, Blast_Score=196, Evalue=5e-50, Organism=Homo sapiens, GI21361144, Length=236, Percent_Identity=42.3728813559322, Blast_Score=195, Evalue=1e-49, Organism=Homo sapiens, GI24430151, Length=244, Percent_Identity=39.7540983606557, Blast_Score=193, Evalue=4e-49, Organism=Homo sapiens, GI89064750, Length=253, Percent_Identity=41.1067193675889, Blast_Score=186, Evalue=5e-47, Organism=Homo sapiens, GI5729991, Length=253, Percent_Identity=41.1067193675889, Blast_Score=186, Evalue=5e-47, Organism=Homo sapiens, GI24430155, Length=253, Percent_Identity=41.1067193675889, Blast_Score=186, Evalue=7e-47, Organism=Homo sapiens, GI195539395, Length=234, Percent_Identity=41.025641025641, Blast_Score=184, Evalue=2e-46, Organism=Homo sapiens, GI157671927, Length=225, Percent_Identity=40.8888888888889, Blast_Score=177, Evalue=2e-44, Organism=Homo sapiens, GI4505725, Length=226, Percent_Identity=41.1504424778761, Blast_Score=172, Evalue=1e-42, Organism=Homo sapiens, GI40806173, Length=137, Percent_Identity=59.1240875912409, Blast_Score=166, Evalue=7e-41, Organism=Homo sapiens, GI229577436, Length=259, Percent_Identity=38.6100386100386, Blast_Score=164, Evalue=2e-40, Organism=Homo sapiens, GI24497618, Length=299, Percent_Identity=36.1204013377926, Blast_Score=163, Evalue=5e-40, Organism=Homo sapiens, GI153792536, Length=242, Percent_Identity=39.2561983471074, Blast_Score=162, Evalue=1e-39, Organism=Homo sapiens, GI5901990, Length=239, Percent_Identity=41.8410041841004, Blast_Score=154, Evalue=4e-37, Organism=Homo sapiens, GI194018488, Length=251, Percent_Identity=41.0358565737052, Blast_Score=151, Evalue=2e-36, Organism=Homo sapiens, GI14149767, Length=248, Percent_Identity=38.3064516129032, Blast_Score=144, Evalue=2e-34, Organism=Homo sapiens, GI62177112, Length=248, Percent_Identity=38.3064516129032, Blast_Score=144, Evalue=2e-34, Organism=Homo sapiens, GI156564401, Length=230, Percent_Identity=37.8260869565217, Blast_Score=142, Evalue=1e-33, Organism=Homo sapiens, GI310125282, Length=230, Percent_Identity=37.3913043478261, Blast_Score=139, Evalue=1e-32, Organism=Homo sapiens, GI310125280, Length=230, Percent_Identity=37.3913043478261, Blast_Score=137, Evalue=2e-32, Organism=Homo sapiens, GI226371754, Length=241, Percent_Identity=35.6846473029046, Blast_Score=137, Evalue=5e-32, Organism=Homo sapiens, GI31377644, Length=251, Percent_Identity=36.2549800796813, Blast_Score=135, Evalue=1e-31, Organism=Homo sapiens, GI7019569, Length=269, Percent_Identity=34.5724907063197, Blast_Score=130, Evalue=3e-30, Organism=Homo sapiens, GI11875211, Length=227, Percent_Identity=39.2070484581498, Blast_Score=130, Evalue=4e-30, Organism=Homo sapiens, GI40806170, Length=227, Percent_Identity=39.2070484581498, Blast_Score=130, Evalue=5e-30, Organism=Homo sapiens, GI31742536, Length=230, Percent_Identity=33.9130434782609, Blast_Score=129, Evalue=1e-29, Organism=Homo sapiens, GI112789543, Length=230, Percent_Identity=33.9130434782609, Blast_Score=129, Evalue=1e-29, Organism=Homo sapiens, GI17865802, Length=251, Percent_Identity=34.6613545816733, Blast_Score=125, Evalue=1e-28, Organism=Homo sapiens, GI64084766, Length=272, Percent_Identity=27.2058823529412, Blast_Score=93, Evalue=6e-19, Organism=Homo sapiens, GI116292174, Length=225, Percent_Identity=29.7777777777778, Blast_Score=72, Evalue=2e-12, Organism=Homo sapiens, GI4757852, Length=160, Percent_Identity=33.125, Blast_Score=71, Evalue=3e-12, Organism=Homo sapiens, GI119964730, Length=160, Percent_Identity=33.125, Blast_Score=71, Evalue=3e-12, Organism=Escherichia coli, GI1789568, Length=492, Percent_Identity=53.6585365853659, Blast_Score=544, Evalue=1e-156, Organism=Caenorhabditis elegans, GI71994521, Length=466, Percent_Identity=50.2145922746781, Blast_Score=429, Evalue=1e-120, Organism=Caenorhabditis elegans, GI17554264, Length=471, Percent_Identity=46.072186836518, Blast_Score=384, Evalue=1e-107, Organism=Caenorhabditis elegans, GI115534323, Length=462, Percent_Identity=44.5887445887446, Blast_Score=366, Evalue=1e-101, Organism=Caenorhabditis elegans, GI17554786, Length=253, Percent_Identity=43.8735177865613, Blast_Score=216, Evalue=3e-56, Organism=Caenorhabditis elegans, GI25144281, Length=253, Percent_Identity=43.0830039525692, Blast_Score=209, Evalue=3e-54, Organism=Caenorhabditis elegans, GI25144278, Length=253, Percent_Identity=43.0830039525692, Blast_Score=209, Evalue=3e-54, Organism=Caenorhabditis elegans, GI17563248, Length=251, Percent_Identity=43.4262948207171, Blast_Score=204, Evalue=1e-52, Organism=Caenorhabditis elegans, GI17508701, Length=240, Percent_Identity=42.5, Blast_Score=196, Evalue=2e-50, Organism=Caenorhabditis elegans, GI17531535, Length=235, Percent_Identity=45.1063829787234, Blast_Score=193, Evalue=3e-49, Organism=Caenorhabditis elegans, GI17563250, Length=244, Percent_Identity=39.7540983606557, Blast_Score=187, Evalue=1e-47, Organism=Caenorhabditis elegans, GI71987364, Length=238, Percent_Identity=41.5966386554622, Blast_Score=187, Evalue=1e-47, Organism=Caenorhabditis elegans, GI71987372, Length=238, Percent_Identity=41.5966386554622, Blast_Score=187, Evalue=2e-47, Organism=Caenorhabditis elegans, GI17532375, Length=225, Percent_Identity=39.1111111111111, Blast_Score=186, Evalue=5e-47, Organism=Caenorhabditis elegans, GI17505546, Length=239, Percent_Identity=41.8410041841004, Blast_Score=184, Evalue=1e-46, Organism=Caenorhabditis elegans, GI17554784, Length=253, Percent_Identity=39.1304347826087, Blast_Score=171, Evalue=9e-43, Organism=Caenorhabditis elegans, GI17508053, Length=237, Percent_Identity=40.9282700421941, Blast_Score=171, Evalue=2e-42, Organism=Caenorhabditis elegans, GI17537217, Length=261, Percent_Identity=38.6973180076628, Blast_Score=166, Evalue=2e-41, Organism=Caenorhabditis elegans, GI25153574, Length=276, Percent_Identity=34.7826086956522, Blast_Score=160, Evalue=2e-39, Organism=Caenorhabditis elegans, GI193209502, Length=268, Percent_Identity=35.0746268656716, Blast_Score=155, Evalue=7e-38, Organism=Caenorhabditis elegans, GI133931034, Length=283, Percent_Identity=35.6890459363958, Blast_Score=154, Evalue=2e-37, Organism=Caenorhabditis elegans, GI193206114, Length=283, Percent_Identity=35.6890459363958, Blast_Score=154, Evalue=2e-37, Organism=Caenorhabditis elegans, GI193206116, Length=283, Percent_Identity=35.6890459363958, Blast_Score=154, Evalue=2e-37, Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=45.4545454545455, Blast_Score=138, Evalue=8e-33, Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=45.4545454545455, Blast_Score=138, Evalue=8e-33, Organism=Caenorhabditis elegans, GI25146157, Length=262, Percent_Identity=38.1679389312977, Blast_Score=137, Evalue=2e-32, Organism=Caenorhabditis elegans, GI86561515, Length=261, Percent_Identity=34.4827586206897, Blast_Score=134, Evalue=2e-31, Organism=Caenorhabditis elegans, GI133901658, Length=220, Percent_Identity=38.6363636363636, Blast_Score=133, Evalue=3e-31, Organism=Caenorhabditis elegans, GI133901662, Length=219, Percent_Identity=38.3561643835616, Blast_Score=133, Evalue=4e-31, Organism=Caenorhabditis elegans, GI17562804, Length=232, Percent_Identity=36.6379310344828, Blast_Score=133, Evalue=4e-31, Organism=Caenorhabditis elegans, GI17541226, Length=236, Percent_Identity=35.5932203389831, Blast_Score=116, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17541224, Length=236, Percent_Identity=35.5932203389831, Blast_Score=116, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17508421, Length=232, Percent_Identity=35.3448275862069, Blast_Score=115, Evalue=1e-25, Organism=Caenorhabditis elegans, GI32563584, Length=228, Percent_Identity=35.5263157894737, Blast_Score=114, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17560432, Length=253, Percent_Identity=32.4110671936759, Blast_Score=111, Evalue=1e-24, Organism=Caenorhabditis elegans, GI71990294, Length=145, Percent_Identity=32.4137931034483, Blast_Score=69, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6320854, Length=501, Percent_Identity=48.9021956087824, Blast_Score=447, Evalue=1e-126, Organism=Saccharomyces cerevisiae, GI6323736, Length=493, Percent_Identity=46.4503042596349, Blast_Score=437, Evalue=1e-123, Organism=Saccharomyces cerevisiae, GI6325281, Length=460, Percent_Identity=44.3478260869565, Blast_Score=392, Evalue=1e-109, Organism=Saccharomyces cerevisiae, GI6321390, Length=241, Percent_Identity=43.9834024896266, Blast_Score=209, Evalue=1e-54, Organism=Saccharomyces cerevisiae, GI6322704, Length=251, Percent_Identity=42.6294820717131, Blast_Score=204, Evalue=4e-53, Organism=Saccharomyces cerevisiae, GI6320077, Length=243, Percent_Identity=44.8559670781893, Blast_Score=201, Evalue=2e-52, Organism=Saccharomyces cerevisiae, GI6320197, Length=244, Percent_Identity=40.1639344262295, Blast_Score=197, Evalue=5e-51, Organism=Saccharomyces cerevisiae, GI6324691, Length=249, Percent_Identity=40.5622489959839, Blast_Score=189, Evalue=1e-48, Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=41.0569105691057, Blast_Score=186, Evalue=1e-47, Organism=Saccharomyces cerevisiae, GI6320602, Length=259, Percent_Identity=39.7683397683398, Blast_Score=175, Evalue=2e-44, Organism=Saccharomyces cerevisiae, GI6322651, Length=257, Percent_Identity=35.408560311284, Blast_Score=163, Evalue=9e-41, Organism=Saccharomyces cerevisiae, GI6324000, Length=232, Percent_Identity=40.0862068965517, Blast_Score=162, Evalue=1e-40, Organism=Saccharomyces cerevisiae, GI6321709, Length=265, Percent_Identity=38.1132075471698, Blast_Score=161, Evalue=3e-40, Organism=Saccharomyces cerevisiae, GI6323429, Length=227, Percent_Identity=39.647577092511, Blast_Score=156, Evalue=8e-39, Organism=Saccharomyces cerevisiae, GI6322994, Length=232, Percent_Identity=36.2068965517241, Blast_Score=156, Evalue=1e-38, Organism=Saccharomyces cerevisiae, GI6319554, Length=219, Percent_Identity=37.8995433789954, Blast_Score=133, Evalue=1e-31, Organism=Saccharomyces cerevisiae, GI6325431, Length=269, Percent_Identity=35.3159851301115, Blast_Score=132, Evalue=2e-31, Organism=Saccharomyces cerevisiae, GI6321465, Length=248, Percent_Identity=37.0967741935484, Blast_Score=130, Evalue=6e-31, Organism=Saccharomyces cerevisiae, GI6325183, Length=256, Percent_Identity=35.9375, Blast_Score=125, Evalue=2e-29, Organism=Saccharomyces cerevisiae, GI6320887, Length=256, Percent_Identity=32.421875, Blast_Score=108, Evalue=2e-24, Organism=Saccharomyces cerevisiae, GI6320583, Length=159, Percent_Identity=34.5911949685535, Blast_Score=85, Evalue=3e-17, Organism=Drosophila melanogaster, GI28574878, Length=526, Percent_Identity=45.2471482889734, Blast_Score=438, Evalue=1e-123, Organism=Drosophila melanogaster, GI24665814, Length=526, Percent_Identity=45.2471482889734, Blast_Score=437, Evalue=1e-123, Organism=Drosophila melanogaster, GI24639391, Length=463, Percent_Identity=45.5723542116631, Blast_Score=392, Evalue=1e-109, Organism=Drosophila melanogaster, GI24658770, Length=494, Percent_Identity=43.5222672064777, Blast_Score=387, Evalue=1e-107, Organism=Drosophila melanogaster, GI19920408, Length=253, Percent_Identity=41.897233201581, Blast_Score=206, Evalue=4e-53, Organism=Drosophila melanogaster, GI24651451, Length=253, Percent_Identity=42.2924901185771, Blast_Score=204, Evalue=2e-52, Organism=Drosophila melanogaster, GI17137738, Length=251, Percent_Identity=43.0278884462151, Blast_Score=202, Evalue=6e-52, Organism=Drosophila melanogaster, GI17738151, Length=240, Percent_Identity=42.5, Blast_Score=199, Evalue=4e-51, Organism=Drosophila melanogaster, GI161076486, Length=226, Percent_Identity=41.1504424778761, Blast_Score=197, Evalue=2e-50, Organism=Drosophila melanogaster, GI17137560, Length=226, Percent_Identity=41.1504424778761, Blast_Score=197, Evalue=2e-50, Organism=Drosophila melanogaster, GI161076488, Length=226, Percent_Identity=41.1504424778761, Blast_Score=197, Evalue=2e-50, Organism=Drosophila melanogaster, GI45554047, Length=169, Percent_Identity=57.396449704142, Blast_Score=194, Evalue=1e-49, Organism=Drosophila melanogaster, GI24649446, Length=244, Percent_Identity=40.5737704918033, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI281365776, Length=230, Percent_Identity=42.6086956521739, Blast_Score=188, Evalue=1e-47, Organism=Drosophila melanogaster, GI24660075, Length=230, Percent_Identity=42.6086956521739, Blast_Score=188, Evalue=1e-47, Organism=Drosophila melanogaster, GI45552965, Length=230, Percent_Identity=42.6086956521739, Blast_Score=187, Evalue=2e-47, Organism=Drosophila melanogaster, GI281361487, Length=240, Percent_Identity=40.4166666666667, Blast_Score=184, Evalue=1e-46, Organism=Drosophila melanogaster, GI19921202, Length=227, Percent_Identity=40.5286343612335, Blast_Score=183, Evalue=3e-46, Organism=Drosophila melanogaster, GI18860063, Length=240, Percent_Identity=40.8333333333333, Blast_Score=183, Evalue=4e-46, Organism=Drosophila melanogaster, GI24652279, Length=189, Percent_Identity=42.8571428571429, Blast_Score=177, Evalue=3e-44, Organism=Drosophila melanogaster, GI24640100, Length=227, Percent_Identity=40.9691629955947, Blast_Score=176, Evalue=4e-44, Organism=Drosophila melanogaster, GI24663015, Length=237, Percent_Identity=39.662447257384, Blast_Score=172, Evalue=8e-43, Organism=Drosophila melanogaster, GI24656820, Length=254, Percent_Identity=37.7952755905512, Blast_Score=162, Evalue=5e-40, Organism=Drosophila melanogaster, GI24656825, Length=254, Percent_Identity=37.7952755905512, Blast_Score=162, Evalue=5e-40, Organism=Drosophila melanogaster, GI281363136, Length=289, Percent_Identity=35.6401384083045, Blast_Score=153, Evalue=5e-37, Organism=Drosophila melanogaster, GI78707192, Length=289, Percent_Identity=35.6401384083045, Blast_Score=153, Evalue=5e-37, Organism=Drosophila melanogaster, GI24644145, Length=234, Percent_Identity=38.8888888888889, Blast_Score=147, Evalue=3e-35, Organism=Drosophila melanogaster, GI21355121, Length=210, Percent_Identity=36.6666666666667, Blast_Score=142, Evalue=9e-34, Organism=Drosophila melanogaster, GI281360144, Length=236, Percent_Identity=38.5593220338983, Blast_Score=140, Evalue=3e-33, Organism=Drosophila melanogaster, GI281360140, Length=236, Percent_Identity=38.5593220338983, Blast_Score=140, Evalue=3e-33, Organism=Drosophila melanogaster, GI281360136, Length=233, Percent_Identity=38.6266094420601, Blast_Score=140, Evalue=3e-33, Organism=Drosophila melanogaster, GI24644411, Length=233, Percent_Identity=38.6266094420601, Blast_Score=140, Evalue=3e-33, Organism=Drosophila melanogaster, GI281360146, Length=236, Percent_Identity=38.5593220338983, Blast_Score=140, Evalue=4e-33, Organism=Drosophila melanogaster, GI281360138, Length=236, Percent_Identity=38.5593220338983, Blast_Score=140, Evalue=4e-33, Organism=Drosophila melanogaster, GI281360142, Length=236, Percent_Identity=38.5593220338983, Blast_Score=139, Evalue=5e-33, Organism=Drosophila melanogaster, GI21357333, Length=236, Percent_Identity=38.5593220338983, Blast_Score=139, Evalue=5e-33, Organism=Drosophila melanogaster, GI28571849, Length=237, Percent_Identity=38.8185654008439, Blast_Score=138, Evalue=1e-32, Organism=Drosophila melanogaster, GI28571847, Length=237, Percent_Identity=38.8185654008439, Blast_Score=138, Evalue=1e-32, Organism=Drosophila melanogaster, GI18859657, Length=235, Percent_Identity=38.2978723404255, Blast_Score=135, Evalue=1e-31, Organism=Drosophila melanogaster, GI20129529, Length=241, Percent_Identity=35.2697095435685, Blast_Score=132, Evalue=8e-31, Organism=Drosophila melanogaster, GI24581396, Length=236, Percent_Identity=38.5593220338983, Blast_Score=130, Evalue=4e-30, Organism=Drosophila melanogaster, GI17864540, Length=227, Percent_Identity=37.4449339207048, Blast_Score=130, Evalue=4e-30, Organism=Drosophila melanogaster, GI28573010, Length=231, Percent_Identity=35.9307359307359, Blast_Score=128, Evalue=1e-29, Organism=Drosophila melanogaster, GI20129423, Length=268, Percent_Identity=32.4626865671642, Blast_Score=126, Evalue=4e-29, Organism=Drosophila melanogaster, GI24639486, Length=208, Percent_Identity=33.1730769230769, Blast_Score=99, Evalue=8e-21, Organism=Drosophila melanogaster, GI20129417, Length=160, Percent_Identity=35, Blast_Score=72, Evalue=1e-12, Organism=Drosophila melanogaster, GI24583262, Length=160, Percent_Identity=35, Blast_Score=72, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR005936 - InterPro: IPR011546 - InterPro: IPR000642 [H]
Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]
EC number: 3.4.24.-
Molecular weight: Translated: 71795; Mature: 71795
Theoretical pI: Translated: 6.55; Mature: 6.55
Prosite motif: PS00674 AAA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYSKLIKHLKAGDIKSLSY CCCCCCCCEEHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCC QPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSLVLPSDTILKEMTAAADKN CCCCCEEEEECCCCCCCEEECCCCCHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCC GTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGGGGARGAMSFGKNKAKSQSKG CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHCCCCCC NVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGARIPAGVLLEGPPGTGKTLLAKAV CEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCCCCCHHHHHHHH AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAERAIIFIDEIDAVGRRRGAGMG CCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEEECHHHHHHHCCCCCC GGNDEREQTLNQLLIEMDGFEGNENIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVK CCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCC GREAILRVHAKNKPLANDVNLKVVAQQTPGFVGADLENVLNEAALVAARRNKIKIDASDI CCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCC DEAEDRVIAGPSKKDRTISQKEREMVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY CCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEEEECCCCCCE MIALPKEDQMLLSKEDLKEQLAGLMGGRVAEEIVFNAQTSGASNDFEQATQIARAMVTEY EEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC GMSEKLGPVQYEGNHAMMPGQISPEKAYSAQTAQMIDDEVRELLNQARNQAADIINENRD CCCCCCCCEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH THKLIAEALLKYETLDAAQIKSIYETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCC >Mature Secondary Structure MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYSKLIKHLKAGDIKSLSY CCCCCCCCEEHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCC QPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSLVLPSDTILKEMTAAADKN CCCCCEEEEECCCCCCCEEECCCCCHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCC GTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGGGGARGAMSFGKNKAKSQSKG CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHCCCCCC NVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGARIPAGVLLEGPPGTGKTLLAKAV CEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCCCCCHHHHHHHH AGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAERAIIFIDEIDAVGRRRGAGMG CCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEEECHHHHHHHCCCCCC GGNDEREQTLNQLLIEMDGFEGNENIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVK CCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCC GREAILRVHAKNKPLANDVNLKVVAQQTPGFVGADLENVLNEAALVAARRNKIKIDASDI CCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCC DEAEDRVIAGPSKKDRTISQKEREMVAYHEAGHTIVGLVLSNARVVHKVTIVPRGRAGGY CCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEEEECCCCCCE MIALPKEDQMLLSKEDLKEQLAGLMGGRVAEEIVFNAQTSGASNDFEQATQIARAMVTEY EEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC GMSEKLGPVQYEGNHAMMPGQISPEKAYSAQTAQMIDDEVRELLNQARNQAADIINENRD CCCCCCCCEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH THKLIAEALLKYETLDAAQIKSIYETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11463916 [H]