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The map label for this gene is ytgG

Identifier: 15673883

GI number: 15673883

Start: 1968989

End: 1969702

Strand: Reverse

Name: ytgG

Synonym: L152419

Alternate gene names: 15673883

Gene position: 1969702-1968989 (Counterclockwise)

Preceding gene: 30024061

Following gene: 15673882

Centisome position: 83.26

GC content: 35.29

Gene sequence:

>714_bases
ATGAAAAAAATAATCACTAAAGATTACGCCACAATGAGTGAACTTGCTGCAGCGATTGTTCTTGATAAGATGATGCTTTC
AAAAAGGGTAAATCTTTCGCTTACAGCGGGAAATACCCCTCTTGGAATGTATGAAATTCTTATTGATAAACTCCAAAAAA
TGAATTTTGATCGCTCAAATATCCATTATTACAATTTTGATGAAGTACCACTTGCTGGTGAACGCTATGGATTAACAATG
AGTGCTTTAAAGACAGCTTTTTATGATCGAGTACATATTGATGATGGTAATCTTCATGAATTAAATGCTCAAAATAATCA
AGTTTTTGATCAAAAAATCTTACAGGACGGTGGGATTGATTTGATTGTTATGGGGATAGGAGAAGATGGTCATTTTTGTG
CAAATATGCCTGGACATACAAGCTTTGAGCGAGAAATTTTTGCTGTTCCATTTGAAGAAGGGGATGAGATTTATCAGTCA
ATCAAAAATTTGACAGATAAAGAACCGGCTTCTCCTTATGTCACTTTTGGTCCACGAACAGTTCTAGCTAGCAAGCAACT
TTTAGTTTTTGCTGACGGAAAAAAGAAAGCAGAGATTATGAAAAAAGTTCTTGAGGGGCCAATCACAGAAGAAATTCCAG
CTTCTATTTTACGGACGCATCCAAATGTTACTTTTATTTTGGATGAAGAAGCCGCTGCTTTACTTGAAAATTAG

Upstream 100 bases:

>100_bases
AAAAGCGGATTTCCGCTTTTTTTATTTTCAACGAGTAGAATTGCTTTAAATAGAATACTTAATCCTGTAAAATAGAAGTA
ACAAGAAAAAAGGAGCTTCT

Downstream 100 bases:

>100_bases
TTGATGAAGACAGTTAGTAAAATAACTGTTTTTATTTATTCGTAAAGGAGGTCAATTTATGATGACATAATTGACTCTAA
ATTATTCTGAAAGCGTTACA

Product: putative 6-phosphogluconolactonase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKKIITKDYATMSELAAAIVLDKMMLSKRVNLSLTAGNTPLGMYEILIDKLQKMNFDRSNIHYYNFDEVPLAGERYGLTM
SALKTAFYDRVHIDDGNLHELNAQNNQVFDQKILQDGGIDLIVMGIGEDGHFCANMPGHTSFEREIFAVPFEEGDEIYQS
IKNLTDKEPASPYVTFGPRTVLASKQLLVFADGKKKAEIMKKVLEGPITEEIPASILRTHPNVTFILDEEAAALLEN

Sequences:

>Translated_237_residues
MKKIITKDYATMSELAAAIVLDKMMLSKRVNLSLTAGNTPLGMYEILIDKLQKMNFDRSNIHYYNFDEVPLAGERYGLTM
SALKTAFYDRVHIDDGNLHELNAQNNQVFDQKILQDGGIDLIVMGIGEDGHFCANMPGHTSFEREIFAVPFEEGDEIYQS
IKNLTDKEPASPYVTFGPRTVLASKQLLVFADGKKKAEIMKKVLEGPITEEIPASILRTHPNVTFILDEEAAALLEN
>Mature_237_residues
MKKIITKDYATMSELAAAIVLDKMMLSKRVNLSLTAGNTPLGMYEILIDKLQKMNFDRSNIHYYNFDEVPLAGERYGLTM
SALKTAFYDRVHIDDGNLHELNAQNNQVFDQKILQDGGIDLIVMGIGEDGHFCANMPGHTSFEREIFAVPFEEGDEIYQS
IKNLTDKEPASPYVTFGPRTVLASKQLLVFADGKKKAEIMKKVLEGPITEEIPASILRTHPNVTFILDEEAAALLEN

Specific function: Unknown

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19923881, Length=246, Percent_Identity=28.8617886178862, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI48994958, Length=232, Percent_Identity=40.948275862069, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1789530, Length=228, Percent_Identity=24.1228070175439, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786893, Length=214, Percent_Identity=25.2336448598131, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17554876, Length=242, Percent_Identity=28.099173553719, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24581960, Length=251, Percent_Identity=28.6852589641434, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19920764, Length=251, Percent_Identity=28.6852589641434, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: NA

Molecular weight: Translated: 26546; Mature: 26546

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIITKDYATMSELAAAIVLDKMMLSKRVNLSLTAGNTPLGMYEILIDKLQKMNFDRSN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCC
IHYYNFDEVPLAGERYGLTMSALKTAFYDRVHIDDGNLHELNAQNNQVFDQKILQDGGID
CEEECCCCCCCCCCCCCHHHHHHHHHHHCEEECCCCCEEEECCCCCHHHHHHHHHCCCCE
LIVMGIGEDGHFCANMPGHTSFEREIFAVPFEEGDEIYQSIKNLTDKEPASPYVTFGPRT
EEEEEECCCCCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCEE
VLASKQLLVFADGKKKAEIMKKVLEGPITEEIPASILRTHPNVTFILDEEAAALLEN
EECCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHCC
>Mature Secondary Structure
MKKIITKDYATMSELAAAIVLDKMMLSKRVNLSLTAGNTPLGMYEILIDKLQKMNFDRSN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCC
IHYYNFDEVPLAGERYGLTMSALKTAFYDRVHIDDGNLHELNAQNNQVFDQKILQDGGID
CEEECCCCCCCCCCCCCHHHHHHHHHHHCEEECCCCCEEEECCCCCHHHHHHHHHCCCCE
LIVMGIGEDGHFCANMPGHTSFEREIFAVPFEEGDEIYQSIKNLTDKEPASPYVTFGPRT
EEEEEECCCCCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCEE
VLASKQLLVFADGKKKAEIMKKVLEGPITEEIPASILRTHPNVTFILDEEAAALLEN
EECCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]