Click here to switch to the map view.

The map label for this gene is infC

Identifier: 15673826

GI number: 15673826

Start: 1911881

End: 1912375

Strand: Reverse

Name: infC

Synonym: L95240

Alternate gene names: 15673826

Gene position: 1912375-1911881 (Counterclockwise)

Preceding gene: 15673828

Following gene: 15673825

Centisome position: 80.84

GC content: 39.19

Gene sequence:

>495_bases
ATGATGAACGGTGCAATCCGTGCTCGTGAGGTTCGTCTCATTGGCGCTGAGGGTGAACAATTAGGTGTCACACCAACGTC
TGAGGCGCTAATGCAAGCTGAAAATCTTAACATGGACTTGGTTTTAATTTCAAACCAAGAACCACCTGTTGCAAAAATCA
TGGATTATACAAAATTCATGTTTGAGCAAAAGAAAAAACAAAAAGAAGCAAAGAAAAAACAAGCTGTTGTTTCTGTAAAA
GAAGTCCGTTTGTCACCAGTAATTGACCAAAACGACTTTGATACAAAGCTTCGTCAAGCCATCAAGTTTCTTGAAAAAGG
CGATAAAGTTAAGGTTTCAATCCGATTTAAAGGTCGGATGATTACTCACCAAGATGTGGGTCGTCAAGTAATGGACAAGT
TCGCGCAAGCAACAAAAGAAGTTGCTGTTGTTGAACAAAGAGCCAAAATGGATGGTCGTCAAATGTTCTTGCAACTTGCA
CCTATTAAAAAATAG

Upstream 100 bases:

>100_bases
TTTTGTTTTTCTTTAAAAAAGAAGTTGCCTAAATCTTAGTCAACTTTCACATCATATTAGAAGGAGAACGAACATAGCTA
AACAAGACAATAGAAAACCT

Downstream 100 bases:

>100_bases
GTCTTAACAAGACAACCATCTGAAAGGTTAACCTTTCACCTCTCTATTCATTGAAAACGAATGTTTAAAATGAATAGAGG
TGCAGAATAATTTTTTCTGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MMNGAIRAREVRLIGAEGEQLGVTPTSEALMQAENLNMDLVLISNQEPPVAKIMDYTKFMFEQKKKQKEAKKKQAVVSVK
EVRLSPVIDQNDFDTKLRQAIKFLEKGDKVKVSIRFKGRMITHQDVGRQVMDKFAQATKEVAVVEQRAKMDGRQMFLQLA
PIKK

Sequences:

>Translated_164_residues
MMNGAIRAREVRLIGAEGEQLGVTPTSEALMQAENLNMDLVLISNQEPPVAKIMDYTKFMFEQKKKQKEAKKKQAVVSVK
EVRLSPVIDQNDFDTKLRQAIKFLEKGDKVKVSIRFKGRMITHQDVGRQVMDKFAQATKEVAVVEQRAKMDGRQMFLQLA
PIKK
>Mature_164_residues
MMNGAIRAREVRLIGAEGEQLGVTPTSEALMQAENLNMDLVLISNQEPPVAKIMDYTKFMFEQKKKQKEAKKKQAVVSVK
EVRLSPVIDQNDFDTKLRQAIKFLEKGDKVKVSIRFKGRMITHQDVGRQVMDKFAQATKEVAVVEQRAKMDGRQMFLQLA
PIKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=165, Percent_Identity=52.1212121212121, Blast_Score=154, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_LACLA (Q9CEJ7)

Other databases:

- EMBL:   AE005176
- PIR:   D86855
- RefSeq:   NP_268001.1
- ProteinModelPortal:   Q9CEJ7
- GeneID:   1115509
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L95240
- NMPDR:   fig|272623.1.peg.2384
- HOGENOM:   HBG744268
- OMA:   KQMKFRL
- ProtClustDB:   PRK00028
- BioCyc:   LLAC272623:L95240-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 18692; Mature: 18692

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNGAIRAREVRLIGAEGEQLGVTPTSEALMQAENLNMDLVLISNQEPPVAKIMDYTKFM
CCCCCCEEEEEEEECCCCCEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHH
FEQKKKQKEAKKKQAVVSVKEVRLSPVIDQNDFDTKLRQAIKFLEKGDKVKVSIRFKGRM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCEE
ITHQDVGRQVMDKFAQATKEVAVVEQRAKMDGRQMFLQLAPIKK
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure
MMNGAIRAREVRLIGAEGEQLGVTPTSEALMQAENLNMDLVLISNQEPPVAKIMDYTKFM
CCCCCCEEEEEEEECCCCCEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHH
FEQKKKQKEAKKKQAVVSVKEVRLSPVIDQNDFDTKLRQAIKFLEKGDKVKVSIRFKGRM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCEE
ITHQDVGRQVMDKFAQATKEVAVVEQRAKMDGRQMFLQLAPIKK
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471