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The map label for this gene is yseI

Identifier: 15673773

GI number: 15673773

Start: 1848841

End: 1850058

Strand: Reverse

Name: yseI

Synonym: L32195

Alternate gene names: 15673773

Gene position: 1850058-1848841 (Counterclockwise)

Preceding gene: 15673774

Following gene: 15673772

Centisome position: 78.21

GC content: 36.95

Gene sequence:

>1218_bases
ATGCTTGAAGGCATCAAAAAAGATTTTCCAGTATTGAATCAAATTGTTAATGATGAACCTTTGGTCTATTTGGACAATGC
GGCAACTACTCAAAAACCTTTGAAGGTTTTGGCTGCGATAAAAGATTATTATGAAAATGATAATGCTAATGTCCACCGTG
GTGTTCATACTTTGGCAGAGCGAGCAACTGAAAAATACGAAGCGGCGCGTGAAAAAGTCCGTCAGTTTATCAATGCTAAA
TCAACAAAAGAGGTTTTGTTTACTAGAGGAACAACGACTTCAATCAACTGGGTTGCTCAGTTTGCCGGGCAAATCTTAAA
AACAGGGGATGAAATTGTCATTTCGATTATGGAACACCATTCTAATATTGTTCCCTGGCAAGAGGTTGCTAAGAAAACTG
GAGCAATCTTAAAGTTTGTCTATCTTAAAGATGGTCAGCTAGATATGGATGATTTACGTAAAAAAATCACTAATCAAACT
AAATTTGTATCGATTGCTCATGTTTCTAATGTATTAGGGACAATTAATCCAGTAGAAGAAATTACCAAAATTGCTCATGA
ACACGGTGCTTACATGGCGGTTGATGGTGCACAATCTACACCACATATGGCGATTGACCTTCAAAAAATGGATGTCGATT
TCTTTGCTTTCTCAGGTCATAAAATGATGGGACCAACTGGAATTGGCGTTCTTTATGGCAAAGAAGAACTTCTAAATCAA
TTTGAACCTGTCGAATTTGGGGGAGAAATGATTGATTTTGTTTATGAAAGTCATTCAACATGGACAGAACTTCCTTGGAA
ATTTGAAGCTGGCACACCTAATATTGCGGGTGCTATTGCTTTAGGAGCTGCAATTGATTATATTCAAGAGCTTGGGATTG
ACCAAATTCATCAGCACGAAATTGAATTGATTGATTACCTAATGCCAAAACTTCAAGAAATTGAAGGCTTAAAGATTTAT
GGACCGAAAGATAATGTAAAAAGAGGCGGTCTAATTGCTTTTAATATTGAAGGACTTCATCCACATGATGTCGCAACTGC
CCTTGATATGGAGGGGGTAGCTGTAAGAGCTGGTCACCATTGTGCTCAACCTTTATTGAATTATCTCGAAACTCCGGCAA
CTGCTAGAGCAAGCTTTTATCTTTATAATACAAAAGCAGATTGTGATAAATTAGTTGAAGCACTTAAAAAAACAAAGGAG
TTTTTCAACCTTGATTAA

Upstream 100 bases:

>100_bases
TTGTTATTCGAGGATTTCTCGGTTCAGTTGTCAGTGAAATTCCTGTCAAATCAGTCCAAGCAGAATTTATTGAAACTATT
GAAAGAAAGCTGGGCATGTA

Downstream 100 bases:

>100_bases
TATGCTTAATTGGGTCGCCTCCCTCCCACTTTGGTTGGCAACCACATTTTTATTTGTTGTTGTTTTCTTTAGAGCTCAAT
GTACTTTTTGGTTAGGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MLEGIKKDFPVLNQIVNDEPLVYLDNAATTQKPLKVLAAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRQFINAK
STKEVLFTRGTTTSINWVAQFAGQILKTGDEIVISIMEHHSNIVPWQEVAKKTGAILKFVYLKDGQLDMDDLRKKITNQT
KFVSIAHVSNVLGTINPVEEITKIAHEHGAYMAVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
FEPVEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEIELIDYLMPKLQEIEGLKIY
GPKDNVKRGGLIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLETPATARASFYLYNTKADCDKLVEALKKTKE
FFNLD

Sequences:

>Translated_405_residues
MLEGIKKDFPVLNQIVNDEPLVYLDNAATTQKPLKVLAAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRQFINAK
STKEVLFTRGTTTSINWVAQFAGQILKTGDEIVISIMEHHSNIVPWQEVAKKTGAILKFVYLKDGQLDMDDLRKKITNQT
KFVSIAHVSNVLGTINPVEEITKIAHEHGAYMAVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
FEPVEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEIELIDYLMPKLQEIEGLKIY
GPKDNVKRGGLIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLETPATARASFYLYNTKADCDKLVEALKKTKE
FFNLD
>Mature_405_residues
MLEGIKKDFPVLNQIVNDEPLVYLDNAATTQKPLKVLAAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRQFINAK
STKEVLFTRGTTTSINWVAQFAGQILKTGDEIVISIMEHHSNIVPWQEVAKKTGAILKFVYLKDGQLDMDDLRKKITNQT
KFVSIAHVSNVLGTINPVEEITKIAHEHGAYMAVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
FEPVEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEIELIDYLMPKLQEIEGLKIY
GPKDNVKRGGLIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLETPATARASFYLYNTKADCDKLVEALKKTKE
FFNLD

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=230, Percent_Identity=28.2608695652174, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI156713448, Length=334, Percent_Identity=26.6467065868263, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1787970, Length=401, Percent_Identity=47.8802992518703, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1789175, Length=400, Percent_Identity=43, Blast_Score=314, Evalue=7e-87,
Organism=Escherichia coli, GI48994898, Length=230, Percent_Identity=28.695652173913, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25143064, Length=234, Percent_Identity=32.9059829059829, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193211090, Length=369, Percent_Identity=27.3712737127371, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319831, Length=228, Percent_Identity=31.140350877193, Blast_Score=116, Evalue=7e-27,
Organism=Drosophila melanogaster, GI20129463, Length=241, Percent_Identity=31.5352697095436, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45270; Mature: 45270

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGIKKDFPVLNQIVNDEPLVYLDNAATTQKPLKVLAAIKDYYENDNANVHRGVHTLAE
CCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RATEKYEAAREKVRQFINAKSTKEVLFTRGTTTSINWVAQFAGQILKTGDEIVISIMEHH
HHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHC
SNIVPWQEVAKKTGAILKFVYLKDGQLDMDDLRKKITNQTKFVSIAHVSNVLGTINPVEE
CCCCCHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHCCCHHEEEHHHHHHHHHCCCHHHH
ITKIAHEHGAYMAVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
HHHHHHHCCCEEEECCCCCCCCEEEEEEECCEEEEEECCCCEECCCCCEEEECHHHHHHC
FEPVEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHE
CCCHHHCHHHHHHHHHCCCCHHCCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
IELIDYLMPKLQEIEGLKIYGPKDNVKRGGLIAFNIEGLHPHDVATALDMEGVAVRAGHH
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEECCHH
CAQPLLNYLETPATARASFYLYNTKADCDKLVEALKKTKEFFNLD
HHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEGIKKDFPVLNQIVNDEPLVYLDNAATTQKPLKVLAAIKDYYENDNANVHRGVHTLAE
CCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RATEKYEAAREKVRQFINAKSTKEVLFTRGTTTSINWVAQFAGQILKTGDEIVISIMEHH
HHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHC
SNIVPWQEVAKKTGAILKFVYLKDGQLDMDDLRKKITNQTKFVSIAHVSNVLGTINPVEE
CCCCCHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHCCCHHEEEHHHHHHHHHCCCHHHH
ITKIAHEHGAYMAVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
HHHHHHHCCCEEEECCCCCCCCEEEEEEECCEEEEEECCCCEECCCCCEEEECHHHHHHC
FEPVEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHE
CCCHHHCHHHHHHHHHCCCCHHCCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
IELIDYLMPKLQEIEGLKIYGPKDNVKRGGLIAFNIEGLHPHDVATALDMEGVAVRAGHH
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEECCHH
CAQPLLNYLETPATARASFYLYNTKADCDKLVEALKKTKEFFNLD
HHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]