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The map label for this gene is tyrA

Identifier: 15673727

GI number: 15673727

Start: 1802927

End: 1803991

Strand: Reverse

Name: tyrA

Synonym: L0058

Alternate gene names: 15673727

Gene position: 1803991-1802927 (Counterclockwise)

Preceding gene: 15673728

Following gene: 15673726

Centisome position: 76.26

GC content: 33.52

Gene sequence:

>1065_bases
ATGAAAAAAATATTAATCATTGGACTTGGTCTCATTGGAAGTTCAATTGCCTTAGGGATAAAAAGAGCTCATCCTGATTT
TGAAATTCTTGGCTCTGATCGTGAGAACATTCAAGAAATTGCTCAAAAGCGTGGAATTATTGATTCTAAAGTTAGCTTAG
TTGAAGGAGCTCAAAAAGCAGATATTATTATTTTGGCTGTTCCAATTATAACCACTTTGGAGCTTTTGAAAAAGCTAGCA
ACTTTGAATTTGAAAAAAGGTCTTTTAATTACAGATACAGGTTCAACCAAGAGTGAAATTGTTGAACTGGCAAATCAACT
TTTTGATGAAGACAAAGTACGATTTATCGGTGGACATCCGATGGCTGGCTCTCATAAATCAGGAGTAATGGCGGCAGATA
TTAATTTATTTGAAAATGCTTATTATGTTTTGACCCAAGAAAACCAAGAATTACGTGATTTACTTAAAGGACTTCATGCC
AAATTTATTATTTTAGATGCAAAAGAGCACGACCGAGTCACTGGGCAGGTTTCTCATTTCCCGCATATTTTGGCTTCGGC
CCTTGTTTGGCAGTCAGATGATTTTTCAAAAGAACATCCTTTAGTGAAACATTTAGCGGCTGGTGGTTTTAGAGATTTAA
CTAGAATTGCAGAGGCTGACAGTTTGATGTGGACAAGTGTCTTATTATCAAATCCAGAAATTACGATTGATAGAATAGAA
AATTTCAAAAAACAATTAGATGAAATTGCTTTAAAAATTGCTAATAAAGATTCTGCAGCTATAGAACACTTTTTTGAACA
AGGTAAAAAAATCCGTCAAGCTATGGAAATTCATAAAGGGGCTCTGCCAAACTTTTATGATTTATTTATTTCGGTTCCCG
ATGAAAAAGGAGTTGTTTTAAAGGTTTTAGGCTTACTAGAAGATTTCTCAATAACAAATGTAAAAATTAATGAAGAAAAT
CGCGAAGATATTCATGGTCAACTTCAAATTTCGTTTAAGAGAGCGGAAGATTTAAAAGAAGCACGAGAAATTATTGAAAA
AGCAACTGATTTTACAGTTGTTTGA

Upstream 100 bases:

>100_bases
TTTATTTATCTAAATTAATTTTAGATAAATTAGAATTTGAAATTTCAATTAACTCTGAAATTGGAAATGGGACGTCTGTG
ACAATAACGAAAGAATAAAA

Downstream 100 bases:

>100_bases
TATAGATTAAAGATAGGACTTTCTTAGTCTTAAAATCTTAGGAAAAATTGTTGAAAATAAAAGGGCTCTGAGCGCCCTTT
TATGCTATAATAAATACTAA

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKKILIIGLGLIGSSIALGIKRAHPDFEILGSDRENIQEIAQKRGIIDSKVSLVEGAQKADIIILAVPIITTLELLKKLA
TLNLKKGLLITDTGSTKSEIVELANQLFDEDKVRFIGGHPMAGSHKSGVMAADINLFENAYYVLTQENQELRDLLKGLHA
KFIILDAKEHDRVTGQVSHFPHILASALVWQSDDFSKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITIDRIE
NFKKQLDEIALKIANKDSAAIEHFFEQGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVLKVLGLLEDFSITNVKINEEN
REDIHGQLQISFKRAEDLKEAREIIEKATDFTVV

Sequences:

>Translated_354_residues
MKKILIIGLGLIGSSIALGIKRAHPDFEILGSDRENIQEIAQKRGIIDSKVSLVEGAQKADIIILAVPIITTLELLKKLA
TLNLKKGLLITDTGSTKSEIVELANQLFDEDKVRFIGGHPMAGSHKSGVMAADINLFENAYYVLTQENQELRDLLKGLHA
KFIILDAKEHDRVTGQVSHFPHILASALVWQSDDFSKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITIDRIE
NFKKQLDEIALKIANKDSAAIEHFFEQGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVLKVLGLLEDFSITNVKINEEN
REDIHGQLQISFKRAEDLKEAREIIEKATDFTVV
>Mature_354_residues
MKKILIIGLGLIGSSIALGIKRAHPDFEILGSDRENIQEIAQKRGIIDSKVSLVEGAQKADIIILAVPIITTLELLKKLA
TLNLKKGLLITDTGSTKSEIVELANQLFDEDKVRFIGGHPMAGSHKSGVMAADINLFENAYYVLTQENQELRDLLKGLHA
KFIILDAKEHDRVTGQVSHFPHILASALVWQSDDFSKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITIDRIE
NFKKQLDEIALKIANKDSAAIEHFFEQGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVLKVLGLLEDFSITNVKINEEN
REDIHGQLQISFKRAEDLKEAREIIEKATDFTVV

Specific function: Unknown

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TYRA_LACLA (Q9CET9)

Other databases:

- EMBL:   AE005176
- PIR:   A86843
- RefSeq:   NP_267901.1
- ProteinModelPortal:   Q9CET9
- SMR:   Q9CET9
- GeneID:   1115408
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0058
- NMPDR:   fig|272623.1.peg.1789
- HOGENOM:   HBG544990
- OMA:   QRAIRWG
- ProtClustDB:   PRK06545
- BioCyc:   LLAC272623:L0058-MONOMER
- BRENDA:   1.3.1.12
- GO:   GO:0005488
- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21363

Pfam domain/function: PF02153 PDH; SSF48179 6DGDH_C_like

EC number: =1.3.1.12

Molecular weight: Translated: 39496; Mature: 39496

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS51176 PDH_ADH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIIGLGLIGSSIALGIKRAHPDFEILGSDRENIQEIAQKRGIIDSKVSLVEGAQKA
CCEEEEEEECHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHCCCCCC
DIIILAVPIITTLELLKKLATLNLKKGLLITDTGSTKSEIVELANQLFDEDKVRFIGGHP
CEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCC
MAGSHKSGVMAADINLFENAYYVLTQENQELRDLLKGLHAKFIILDAKEHDRVTGQVSHF
CCCCCCCCEEEEEHHHHCCEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHH
PHILASALVWQSDDFSKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITIDRIE
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHH
NFKKQLDEIALKIANKDSAAIEHFFEQGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCCCCHHH
KVLGLLEDFSITNVKINEENREDIHGQLQISFKRAEDLKEAREIIEKATDFTVV
HHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKILIIGLGLIGSSIALGIKRAHPDFEILGSDRENIQEIAQKRGIIDSKVSLVEGAQKA
CCEEEEEEECHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHCCCCCC
DIIILAVPIITTLELLKKLATLNLKKGLLITDTGSTKSEIVELANQLFDEDKVRFIGGHP
CEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCC
MAGSHKSGVMAADINLFENAYYVLTQENQELRDLLKGLHAKFIILDAKEHDRVTGQVSHF
CCCCCCCCEEEEEHHHHCCEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHH
PHILASALVWQSDDFSKEHPLVKHLAAGGFRDLTRIAEADSLMWTSVLLSNPEITIDRIE
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHH
NFKKQLDEIALKIANKDSAAIEHFFEQGKKIRQAMEIHKGALPNFYDLFISVPDEKGVVL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCCCCHHH
KVLGLLEDFSITNVKINEENREDIHGQLQISFKRAEDLKEAREIIEKATDFTVV
HHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471