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The map label for this gene is rgrB

Identifier: 15673419

GI number: 15673419

Start: 1460974

End: 1461681

Strand: Reverse

Name: rgrB

Synonym: L0151

Alternate gene names: 15673419

Gene position: 1461681-1460974 (Counterclockwise)

Preceding gene: 15673420

Following gene: 15673416

Centisome position: 61.79

GC content: 37.15

Gene sequence:

>708_bases
ATGGCAAGAAAATCAGTACCGAATTATGTAAAAATACATGATGCCTTAAAAGATGAAGTTGAAAAAGGCATCTGGAAAAT
TGGACAACGTCTTCCAAGCGAACGTGATTTGGCCGAGCGTTTTACTGTCAGTCGAATGACAGCAAGACAAGCGGTAACAG
CTTTGGTTGATGAAGGAATTCTTGACCGTCGTGTGGGTTCTGGAACTTATGTTGCTAGCCGACGTGTTCGCGAAAAAATG
CGTGGAACAACTTCCTTTACAGAAATTATCAGCTCACAAGGTAAAGTTCCTTCAACAGAAGTTTTGAGTTATATTAGAAC
GGCGCCAAATGAGGTTGAATGTGAAAAACTAAATATCACCAAAAAGGATTCCATCATCCGAATGGAGCGGATTCGTTATG
CGGATAATGTTCCAATTTGTTATGAAGTGGCAAGCATTCCTTTCAAATTGGTCAAATCTTTTGATAAAAAAGAAATTACT
AGTAACTTCTTTAAAACTTTAGAAAGTCACGGACATGTGATTGGTCGTAGTGAACAGATTGTTTCAGCTAAAAGAGTCAG
TACAGAGGTTTCAGAGTATTTAAAAACAAGAGTTGGAGCTGCTATTCTTGGTTTAACTCAGGTTTCTTATTTAACAGATG
GTACAGCTTTTGAATATGTCTTATCTCAATATGTTGGTGACCGTTTTGAATTTTATTTGGAAAGATAA

Upstream 100 bases:

>100_bases
TATTTTAAATGTTCTTTATTTGTAAGTCATATGAACTGTGATATAATGGTAGACAGATATTAAAGTGGTATATATTGTTA
TTATTTAGTTAGGGGGAACT

Downstream 100 bases:

>100_bases
AAAGGACTTAGTGAAGTCCTTTTTTTGCTTGCCGACGATATTTGTACTGACGAAGTTGAAAATGAATCCAACATCCTATA
CAAAAACCACTTAAAGCAAT

Product: GntR family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MARKSVPNYVKIHDALKDEVEKGIWKIGQRLPSERDLAERFTVSRMTARQAVTALVDEGILDRRVGSGTYVASRRVREKM
RGTTSFTEIISSQGKVPSTEVLSYIRTAPNEVECEKLNITKKDSIIRMERIRYADNVPICYEVASIPFKLVKSFDKKEIT
SNFFKTLESHGHVIGRSEQIVSAKRVSTEVSEYLKTRVGAAILGLTQVSYLTDGTAFEYVLSQYVGDRFEFYLER

Sequences:

>Translated_235_residues
MARKSVPNYVKIHDALKDEVEKGIWKIGQRLPSERDLAERFTVSRMTARQAVTALVDEGILDRRVGSGTYVASRRVREKM
RGTTSFTEIISSQGKVPSTEVLSYIRTAPNEVECEKLNITKKDSIIRMERIRYADNVPICYEVASIPFKLVKSFDKKEIT
SNFFKTLESHGHVIGRSEQIVSAKRVSTEVSEYLKTRVGAAILGLTQVSYLTDGTAFEYVLSQYVGDRFEFYLER
>Mature_234_residues
ARKSVPNYVKIHDALKDEVEKGIWKIGQRLPSERDLAERFTVSRMTARQAVTALVDEGILDRRVGSGTYVASRRVREKMR
GTTSFTEIISSQGKVPSTEVLSYIRTAPNEVECEKLNITKKDSIIRMERIRYADNVPICYEVASIPFKLVKSFDKKEITS
NFFKTLESHGHVIGRSEQIVSAKRVSTEVSEYLKTRVGAAILGLTQVSYLTDGTAFEYVLSQYVGDRFEFYLER

Specific function: Acts as a weak repressor of yflG expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=228, Percent_Identity=31.5789473684211, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI87082252, Length=204, Percent_Identity=26.4705882352941, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790118, Length=213, Percent_Identity=28.169014084507, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788418, Length=235, Percent_Identity=26.8085106382979, Blast_Score=84, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26732; Mature: 26601

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKSVPNYVKIHDALKDEVEKGIWKIGQRLPSERDLAERFTVSRMTARQAVTALVDEGI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRRVGSGTYVASRRVREKMRGTTSFTEIISSQGKVPSTEVLSYIRTAPNEVECEKLNIT
HHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCCC
KKDSIIRMERIRYADNVPICYEVASIPFKLVKSFDKKEITSNFFKTLESHGHVIGRSEQI
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VSAKRVSTEVSEYLKTRVGAAILGLTQVSYLTDGTAFEYVLSQYVGDRFEFYLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHCC
>Mature Secondary Structure 
ARKSVPNYVKIHDALKDEVEKGIWKIGQRLPSERDLAERFTVSRMTARQAVTALVDEGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRRVGSGTYVASRRVREKMRGTTSFTEIISSQGKVPSTEVLSYIRTAPNEVECEKLNIT
HHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCCC
KKDSIIRMERIRYADNVPICYEVASIPFKLVKSFDKKEITSNFFKTLESHGHVIGRSEQI
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VSAKRVSTEVSEYLKTRVGAAILGLTQVSYLTDGTAFEYVLSQYVGDRFEFYLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]