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The map label for this gene is murI

Identifier: 15673264

GI number: 15673264

Start: 1312345

End: 1313160

Strand: Reverse

Name: murI

Synonym: L0120

Alternate gene names: 15673264

Gene position: 1313160-1312345 (Counterclockwise)

Preceding gene: 15673265

Following gene: 15673263

Centisome position: 55.51

GC content: 37.38

Gene sequence:

>816_bases
ATGGACAATCGACCAATCGGCCTCTTAGATTCTGGTGTTGGTGGACTGACTGTTGCTCGCGAACTCCTTAGACAACTCCC
AAATGAAGAAATTGTCTACATAGGAGATACAAGAAGAGCTCCTTATGGTCCGCGTAGTCGTGAACAAATCATTGCGTTCA
CTTGGGACATGGTTAATTTTTTACTATCAAAAGATGTGAAAATGATTGTAATGGCCTGTAATACAGCAACAGCGATGGCC
TTAGAAATTGTAAAAGAAAAACTAGATATACCGGTGATTGGTGTCATCCTACCCGGAGCAAGCTCAGCGATTCAAAAAAC
AAAAACAAACAAAATTGGTGTAATTGCCACTCAAGCTTCTATTCGTTCAGATGAATATCATAAAACAATTGCTCGTAAAT
CATCAGCAGTAGAAGTATATAGCCTAGCATGTCCAAAATTTGTTTCAATCGTTGAATCAAATGAAATGGAATCTGAAATT
GCTAGAAAAGTTGTATCAGAAAGTCTTGTTCCACTAATTGGAAAAGTAGACACCTTAATTCTCGGATGTACTCACTATCC
TCTCTTACGTTCCTTAATCCAAGAAACAATGGGAAAAGAGGTACGTTTGATTGATTCTGGAGCAGAAGCTGTACGAGATA
TCTCTGTTCTGCTCAACTATTTTTCAATAAATGGACAAGAACGTCAACCATTAGAGCATCGTTTCTATACTACTGCGGGC
GTTAATTCATTTCGAGAAATTGCAGAAAAATGGTTAAACATCGGACAACTTCAGATTGAACATACTGAAATAGAGAATTT
CAATAAGGAAAAATAA

Upstream 100 bases:

>100_bases
GTTTGCTTTTATCATCATAAATAAAGTATCCATTATATTAAAAAATACAGATTTTGGATAAGAGAGAATTTGAATTAGAT
ATTTTAAAAGGAGAAGAAAA

Downstream 100 bases:

>100_bases
ATGGAAAAAACACTTATAATCGCAACAAGAAATTCAGGAAAAACAAAAGAATTTAAGAAATTATTTGCTGATTTCGGTTA
TGAAATCAAAGATTTAACAG

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MDNRPIGLLDSGVGGLTVARELLRQLPNEEIVYIGDTRRAPYGPRSREQIIAFTWDMVNFLLSKDVKMIVMACNTATAMA
LEIVKEKLDIPVIGVILPGASSAIQKTKTNKIGVIATQASIRSDEYHKTIARKSSAVEVYSLACPKFVSIVESNEMESEI
ARKVVSESLVPLIGKVDTLILGCTHYPLLRSLIQETMGKEVRLIDSGAEAVRDISVLLNYFSINGQERQPLEHRFYTTAG
VNSFREIAEKWLNIGQLQIEHTEIENFNKEK

Sequences:

>Translated_271_residues
MDNRPIGLLDSGVGGLTVARELLRQLPNEEIVYIGDTRRAPYGPRSREQIIAFTWDMVNFLLSKDVKMIVMACNTATAMA
LEIVKEKLDIPVIGVILPGASSAIQKTKTNKIGVIATQASIRSDEYHKTIARKSSAVEVYSLACPKFVSIVESNEMESEI
ARKVVSESLVPLIGKVDTLILGCTHYPLLRSLIQETMGKEVRLIDSGAEAVRDISVLLNYFSINGQERQPLEHRFYTTAG
VNSFREIAEKWLNIGQLQIEHTEIENFNKEK
>Mature_271_residues
MDNRPIGLLDSGVGGLTVARELLRQLPNEEIVYIGDTRRAPYGPRSREQIIAFTWDMVNFLLSKDVKMIVMACNTATAMA
LEIVKEKLDIPVIGVILPGASSAIQKTKTNKIGVIATQASIRSDEYHKTIARKSSAVEVYSLACPKFVSIVESNEMESEI
ARKVVSESLVPLIGKVDTLILGCTHYPLLRSLIQETMGKEVRLIDSGAEAVRDISVLLNYFSINGQERQPLEHRFYTTAG
VNSFREIAEKWLNIGQLQIEHTEIENFNKEK

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=224, Percent_Identity=31.25, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_LACLA (Q9CG28)

Other databases:

- EMBL:   AE005176
- PIR:   B86785
- RefSeq:   NP_267438.1
- ProteinModelPortal:   Q9CG28
- SMR:   Q9CG28
- GeneID:   1114931
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0120
- NMPDR:   fig|272623.1.peg.1317
- HOGENOM:   HBG645102
- OMA:   AILGCTH
- ProtClustDB:   PRK00865
- BioCyc:   LLAC272623:L0120-MONOMER
- BRENDA:   5.1.1.3
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 30219; Mature: 30219

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRPIGLLDSGVGGLTVARELLRQLPNEEIVYIGDTRRAPYGPRSREQIIAFTWDMVNF
CCCCCCCEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHEEEHHHHHHHH
LLSKDVKMIVMACNTATAMALEIVKEKLDIPVIGVILPGASSAIQKTKTNKIGVIATQAS
HHHCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCEEEEEECHH
IRSDEYHKTIARKSSAVEVYSLACPKFVSIVESNEMESEIARKVVSESLVPLIGKVDTLI
HCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGCTHYPLLRSLIQETMGKEVRLIDSGAEAVRDISVLLNYFSINGQERQPLEHRFYTTAG
CCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
VNSFREIAEKWLNIGQLQIEHTEIENFNKEK
HHHHHHHHHHHHCCCCEEEEHHHHCCCCCCC
>Mature Secondary Structure
MDNRPIGLLDSGVGGLTVARELLRQLPNEEIVYIGDTRRAPYGPRSREQIIAFTWDMVNF
CCCCCCCEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHEEEHHHHHHHH
LLSKDVKMIVMACNTATAMALEIVKEKLDIPVIGVILPGASSAIQKTKTNKIGVIATQAS
HHHCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCEEEEEECHH
IRSDEYHKTIARKSSAVEVYSLACPKFVSIVESNEMESEIARKVVSESLVPLIGKVDTLI
HCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGCTHYPLLRSLIQETMGKEVRLIDSGAEAVRDISVLLNYFSINGQERQPLEHRFYTTAG
CCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
VNSFREIAEKWLNIGQLQIEHTEIENFNKEK
HHHHHHHHHHHHCCCCEEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471