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The map label for this gene is glpD

Identifier: 15673227

GI number: 15673227

Start: 1270095

End: 1271924

Strand: Reverse

Name: glpD

Synonym: L0013

Alternate gene names: 15673227

Gene position: 1271924-1270095 (Counterclockwise)

Preceding gene: 15673228

Following gene: 15673226

Centisome position: 53.77

GC content: 43.55

Gene sequence:

>1830_bases
ATGGCTTTTTCTAAAAAAACAAGACAAGAAGCAATCACAAAAATTCAAAATGAAGAGATGGATTTACTCGTTATCGGAGG
AGGGATCACTGGTGCTGGTTTGACATTACAAGCGGCGGCTGCTGGCATGAAAGTTGCTGTACTTGAAATGCAGGATTTCT
CAGAAGGGACATCCTCACGCTCAACAAAACTCGTGCATGGTGGCATCCGTTACCTCAAAAACTTCGATGTCGAAGTCGTT
TCCGATACAGTTTCAGAACGCGCTGTTGTTCAAGGCATTGCGCCACATATTCCTAAGCCAGATCCGATGTTACTTCCTAT
CTACGATGATGAAGGCAAGACAACGTTTGATATGTTTTCTGTGAAAATTGCGATGGATTTGTATGACCGTTTGGCCGGTG
TGGATGAAGATTCGCCATATGCCAACTACACTATCTCACCAGAAGAAGTCCTGCGCCGCGAGCCACTCATCAAGAAAAAA
GGTTTGCAAGGGGCTGGAGTCTATCTTGACTACCGTAACAACGATGCCCGCTTGGTGATTGATAACATCAAAAAAGCTGT
GGAAGACGGTGCCCAAGCCATAAGCAAGATGAAAGTGATTGATTTTATCTATACGGATGGACAAATTTCTGGTATTCGTG
CGCGTGATTTGTTGACAGATCAAGTCATTGAAGTCAAAGCTAAACTTGTGATTAACACAAGTGGACCTTGGGTAGATAAG
ATCCGTTACCTGAACTTCACTCGTCCCATCGTGCCCAAAATGCGTCCAACAAAAGGTGTCCATCTTGTAGTAGATGCGGC
CAAATTGCCTGTACCACAACCAACTTATTTTGATACAGGCAAACACGATAAACGCATGGTCTTTGCCATTCCACGTGAAA
ATAAAACTTATTTTGGTACGACAGATACGGATTATCATGGCGACTTTACCGATCCAAAAGTAACTCAAGAAGATGTAGAT
TACCTCTTGGATGTTATTAATTTCCGTTACCCAGAAGCAAATATTACGATTAATGACATCGAAGCTTCATGGGCAGGATT
GCGTCCATTGTTAGGCGGAAATTCTGGATCAGACTATAACGGCGGTGATAATGGTGCGGTCTCTGAAACCAGCTTTAACG
CTGTCGTTGAGGCGGTGCTCCGCTATAAAAATAAAACAGCAACAAAAGCCGAAGTGGAGCATTTGTTGAACAATATGGAA
TCAAGCCTTTCCGAAAAAGGAGATGCACCATCTTCCGTTTCTCGTGGCAGCTCACTTGAACGCGAGAGCGATGGTTTGAT
TACTTTAGCGGGTGGTAAAATCACGGACTACCGTAAAATGGCGGCAGGTGCGATGGAGCTTATTTGCCAATTGCTTGAGG
AGGACTTTGGTTTGAAATACGAACCTATTGACTCTAAAAAATACCAAATCTCTGGTGGCGAATTTGACCCAACTAAAGTT
GAAGAAGTTGTTGCTGAAAACATGAAAGTTGGTGTCGCTGCAGGTCTTACAGAAGAAGAAGCAAAATACATTGCTGACTT
TTATGGTATGAATGCACTCCAAGTCTTTGCCTATGCTTCTGAAATGGAAGCTTATGAAGGCTTATCTCTAGCCGAATCCG
CACGTCTTTGCTATGCGCTTGAGGATGAAATGATCTTAACACCAGTGGACTACTTGCTTCGTCGTACCAACCACATCTTG
TTTATGCGTGAAGGAGTAGATGCTATCAAGGTACATGTTGTCAATGCCATGGCGGACGACCTTGGCTGGTCTGCAGAAGA
AAAGGCAGAACAAGAAAAAGCTTTGGAAGAAGCACTTCGTGAATCGGACTTGTCGGATTTGAAGAAGTAA

Upstream 100 bases:

>100_bases
ACGTAGAGAAGAACTCTATGCCGGTTGGAAAAAAGCCGTGAATGCGACACGTGCTTTCAAATAATAATCAATCAGACAGT
AATCTAAAAGGAGAATAGAA

Downstream 100 bases:

>100_bases
AAAATGCAAAAATGATTGAAACAAATAAAAAATAGAAATAAGGGGTCAATATGCACTCAGAAATGGTACAGCTACTTGGT
GAATTTTTAGGAACATTTAT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: Glycerol-3-phosphate oxidase

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MAFSKKTRQEAITKIQNEEMDLLVIGGGITGAGLTLQAAAAGMKVAVLEMQDFSEGTSSRSTKLVHGGIRYLKNFDVEVV
SDTVSERAVVQGIAPHIPKPDPMLLPIYDDEGKTTFDMFSVKIAMDLYDRLAGVDEDSPYANYTISPEEVLRREPLIKKK
GLQGAGVYLDYRNNDARLVIDNIKKAVEDGAQAISKMKVIDFIYTDGQISGIRARDLLTDQVIEVKAKLVINTSGPWVDK
IRYLNFTRPIVPKMRPTKGVHLVVDAAKLPVPQPTYFDTGKHDKRMVFAIPRENKTYFGTTDTDYHGDFTDPKVTQEDVD
YLLDVINFRYPEANITINDIEASWAGLRPLLGGNSGSDYNGGDNGAVSETSFNAVVEAVLRYKNKTATKAEVEHLLNNME
SSLSEKGDAPSSVSRGSSLERESDGLITLAGGKITDYRKMAAGAMELICQLLEEDFGLKYEPIDSKKYQISGGEFDPTKV
EEVVAENMKVGVAAGLTEEEAKYIADFYGMNALQVFAYASEMEAYEGLSLAESARLCYALEDEMILTPVDYLLRRTNHIL
FMREGVDAIKVHVVNAMADDLGWSAEEKAEQEKALEEALRESDLSDLKK

Sequences:

>Translated_609_residues
MAFSKKTRQEAITKIQNEEMDLLVIGGGITGAGLTLQAAAAGMKVAVLEMQDFSEGTSSRSTKLVHGGIRYLKNFDVEVV
SDTVSERAVVQGIAPHIPKPDPMLLPIYDDEGKTTFDMFSVKIAMDLYDRLAGVDEDSPYANYTISPEEVLRREPLIKKK
GLQGAGVYLDYRNNDARLVIDNIKKAVEDGAQAISKMKVIDFIYTDGQISGIRARDLLTDQVIEVKAKLVINTSGPWVDK
IRYLNFTRPIVPKMRPTKGVHLVVDAAKLPVPQPTYFDTGKHDKRMVFAIPRENKTYFGTTDTDYHGDFTDPKVTQEDVD
YLLDVINFRYPEANITINDIEASWAGLRPLLGGNSGSDYNGGDNGAVSETSFNAVVEAVLRYKNKTATKAEVEHLLNNME
SSLSEKGDAPSSVSRGSSLERESDGLITLAGGKITDYRKMAAGAMELICQLLEEDFGLKYEPIDSKKYQISGGEFDPTKV
EEVVAENMKVGVAAGLTEEEAKYIADFYGMNALQVFAYASEMEAYEGLSLAESARLCYALEDEMILTPVDYLLRRTNHIL
FMREGVDAIKVHVVNAMADDLGWSAEEKAEQEKALEEALRESDLSDLKK
>Mature_608_residues
AFSKKTRQEAITKIQNEEMDLLVIGGGITGAGLTLQAAAAGMKVAVLEMQDFSEGTSSRSTKLVHGGIRYLKNFDVEVVS
DTVSERAVVQGIAPHIPKPDPMLLPIYDDEGKTTFDMFSVKIAMDLYDRLAGVDEDSPYANYTISPEEVLRREPLIKKKG
LQGAGVYLDYRNNDARLVIDNIKKAVEDGAQAISKMKVIDFIYTDGQISGIRARDLLTDQVIEVKAKLVINTSGPWVDKI
RYLNFTRPIVPKMRPTKGVHLVVDAAKLPVPQPTYFDTGKHDKRMVFAIPRENKTYFGTTDTDYHGDFTDPKVTQEDVDY
LLDVINFRYPEANITINDIEASWAGLRPLLGGNSGSDYNGGDNGAVSETSFNAVVEAVLRYKNKTATKAEVEHLLNNMES
SLSEKGDAPSSVSRGSSLERESDGLITLAGGKITDYRKMAAGAMELICQLLEEDFGLKYEPIDSKKYQISGGEFDPTKVE
EVVAENMKVGVAAGLTEEEAKYIADFYGMNALQVFAYASEMEAYEGLSLAESARLCYALEDEMILTPVDYLLRRTNHILF
MREGVDAIKVHVVNAMADDLGWSAEEKAEQEKALEEALRESDLSDLKK

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI285002233, Length=610, Percent_Identity=30.1639344262295, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI285002231, Length=610, Percent_Identity=30.1639344262295, Blast_Score=230, Evalue=3e-60,
Organism=Escherichia coli, GI2367226, Length=524, Percent_Identity=26.1450381679389, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788574, Length=424, Percent_Identity=25.4716981132075, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17509253, Length=611, Percent_Identity=29.4599018003273, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI115534726, Length=611, Percent_Identity=28.6415711947627, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6322036, Length=646, Percent_Identity=27.3993808049536, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI161077125, Length=616, Percent_Identity=29.2207792207792, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24653942, Length=616, Percent_Identity=29.2207792207792, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24653944, Length=616, Percent_Identity=29.2207792207792, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI20130025, Length=616, Percent_Identity=29.2207792207792, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI19921278, Length=616, Percent_Identity=26.2987012987013, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24586295, Length=359, Percent_Identity=29.5264623955432, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI45550977, Length=461, Percent_Identity=24.5119305856833, Blast_Score=103, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPO_LACLA (Q9CG65)

Other databases:

- EMBL:   AE005176
- EMBL:   AF001829
- PIR:   E86780
- RefSeq:   NP_267401.1
- ProteinModelPortal:   Q9CG65
- SMR:   Q9CG65
- GeneID:   1114894
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0013
- NMPDR:   fig|272623.1.peg.1280
- HOGENOM:   HBG720894
- OMA:   HAKLVIN
- ProtClustDB:   CLSK2750091
- BioCyc:   LLAC272623:L0013-MONOMER
- BRENDA:   1.1.3.21
- InterPro:   IPR006076
- InterPro:   IPR000447
- PRINTS:   PR01001

Pfam domain/function: PF01266 DAO

EC number: =1.1.3.21

Molecular weight: Translated: 67311; Mature: 67180

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00977 FAD_G3PDH_1; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSKKTRQEAITKIQNEEMDLLVIGGGITGAGLTLQAAAAGMKVAVLEMQDFSEGTSSR
CCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHCCCEEEEEEEHHCCCCCCCC
STKLVHGGIRYLKNFDVEVVSDTVSERAVVQGIAPHIPKPDPMLLPIYDDEGKTTFDMFS
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEHHHH
VKIAMDLYDRLAGVDEDSPYANYTISPEEVLRREPLIKKKGLQGAGVYLDYRNNDARLVI
HHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHCCCCHHHCCCCCCCEEEEEECCCCEEEH
DNIKKAVEDGAQAISKMKVIDFIYTDGQISGIRARDLLTDQVIEVKAKLVINTSGPWVDK
HHHHHHHHHHHHHHHHHEEEEEEEECCEECCEEHHHHHHHHHHEEEEEEEEECCCCHHHH
IRYLNFTRPIVPKMRPTKGVHLVVDAAKLPVPQPTYFDTGKHDKRMVFAIPRENKTYFGT
HEEECCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEECC
TDTDYHGDFTDPKVTQEDVDYLLDVINFRYPEANITINDIEASWAGLRPLLGGNSGSDYN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHCCCCCCCCCCCCCCC
GGDNGAVSETSFNAVVEAVLRYKNKTATKAEVEHLLNNMESSLSEKGDAPSSVSRGSSLE
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
RESDGLITLAGGKITDYRKMAAGAMELICQLLEEDFGLKYEPIDSKKYQISGGEFDPTKV
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCHHHH
EEVVAENMKVGVAAGLTEEEAKYIADFYGMNALQVFAYASEMEAYEGLSLAESARLCYAL
HHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEEE
EDEMILTPVDYLLRRTNHILFMREGVDAIKVHVVNAMADDLGWSAEEKAEQEKALEEALR
CCCEEECCHHHHHHHCCCEEEEECCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ESDLSDLKK
HCCHHHHCC
>Mature Secondary Structure 
AFSKKTRQEAITKIQNEEMDLLVIGGGITGAGLTLQAAAAGMKVAVLEMQDFSEGTSSR
CCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHCCCEEEEEEEHHCCCCCCCC
STKLVHGGIRYLKNFDVEVVSDTVSERAVVQGIAPHIPKPDPMLLPIYDDEGKTTFDMFS
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEHHHH
VKIAMDLYDRLAGVDEDSPYANYTISPEEVLRREPLIKKKGLQGAGVYLDYRNNDARLVI
HHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHCCCCHHHCCCCCCCEEEEEECCCCEEEH
DNIKKAVEDGAQAISKMKVIDFIYTDGQISGIRARDLLTDQVIEVKAKLVINTSGPWVDK
HHHHHHHHHHHHHHHHHEEEEEEEECCEECCEEHHHHHHHHHHEEEEEEEEECCCCHHHH
IRYLNFTRPIVPKMRPTKGVHLVVDAAKLPVPQPTYFDTGKHDKRMVFAIPRENKTYFGT
HEEECCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEECC
TDTDYHGDFTDPKVTQEDVDYLLDVINFRYPEANITINDIEASWAGLRPLLGGNSGSDYN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHCCCCCCCCCCCCCCC
GGDNGAVSETSFNAVVEAVLRYKNKTATKAEVEHLLNNMESSLSEKGDAPSSVSRGSSLE
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
RESDGLITLAGGKITDYRKMAAGAMELICQLLEEDFGLKYEPIDSKKYQISGGEFDPTKV
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCHHHH
EEVVAENMKVGVAAGLTEEEAKYIADFYGMNALQVFAYASEMEAYEGLSLAESARLCYAL
HHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEEE
EDEMILTPVDYLLRRTNHILFMREGVDAIKVHVVNAMADDLGWSAEEKAEQEKALEEALR
CCCEEECCHHHHHHHCCCEEEEECCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ESDLSDLKK
HCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471; 9212417