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The map label for this gene is xerS

Identifier: 15673214

GI number: 15673214

Start: 1258157

End: 1259227

Strand: Reverse

Name: xerS

Synonym: L57903

Alternate gene names: 15673214

Gene position: 1259227-1258157 (Counterclockwise)

Preceding gene: 30024030

Following gene: 15673201

Centisome position: 53.23

GC content: 33.52

Gene sequence:

>1071_bases
ATGAAACGTGAACAATTAATACAAAATATTGAAAAACTAAAACACATCATGCCTTCTTATGTTTTAGAATATTATCAATC
TAAACTTACTATTCCTTATAGTTTGAATACACTTTATGAATATCTTAAAGAATATGAACGTTTCTTTAGTTGGTTGGTCG
ATTCTGGAGTTGCTGATGTTGATAAGATAACTGATGTTTCCCTCTCTGTTTTAGAAAACTTAACTAAACGAGATTTGGAG
TCATTTATCCTCTATCTTAGGGAGAGACCCCGTTTAAATACGCGCTCTACTCGTTATGGGGTAAGTCAAACAACAATTAA
TCGTACTCTATCTGCTCTTTCTAGTCTTTATAAATACCTTACTGAAGAGGTTGAAAATGAAGATGGTGAGCCTTACTTCT
ATCGTAATGTTATGAAGAAGGTACAGACTAAGAAAAAATCCGAAACTTTAGCTTCTCGTGCTGAGAATATTAAAGGGAAG
CTTTTTTTGGGAGATGAAACTCAAGGTTTTCTTGACTATATTGATAATGAATATGAAAAAACATTATCAAATAGAGCTCG
TTCTAGTTTTTTCAAAAATAAAGAACGTGATTTAGCAATTATTGCACTTATTTTAGCCTCTGGTATTCGTCTTTCTGAGG
CAGTTAATGTAGATTTAAGAGATTTAAATCTTATTACTATGGTTGTTGAGGTAACTCGTAAAGGAGGAAAAAGGGATGCT
GTTCCTTATGCTCCTTTTGCCAAAACTTATTTTGAAAGATACTTGGAAGTACGAAGTCAACGTTATAAGACTACAGCGAA
AGATACGGCATTTTTTGTGACACTTTATAGAGACGTTCCTAGCCGAATAGATCCTTCTAGTGTTGAAAAATTAGTTGCTA
AATATTCTCAAGCTTTTAAAGTGCGAGTGACCCCTCACAAGCTTAGACATACACTTGCGACTCGACTTTATGCTCAAACA
AATTCTCAGGTATTGGTGAGCAATCAGTTAGGGCATGCTTCAACTCAAGTTACAGACCTTTATACTCATATTATCAATGA
AGAACAAAAAAATGCTCTAGATAATCTATAA

Upstream 100 bases:

>100_bases
AAATGTGTGACACAGAACTCCTATATGTTTTAAGTAACATCTTTCCGAAAAACTGTAATTTTCTTGACAATTGGATATCT
CTTCTGGTATACTTAAATTT

Downstream 100 bases:

>100_bases
CAAATAAAAAACACTTGATTCAAATTCCAAGTGTTTTTTATTTGTTATAGATTATCTTTTGAAATAATATCTGTTAAGCT
ATTTAAAGCACGCTCTGCTA

Product: site-specific tyrosine recombinase XerS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKREQLIQNIEKLKHIMPSYVLEYYQSKLTIPYSLNTLYEYLKEYERFFSWLVDSGVADVDKITDVSLSVLENLTKRDLE
SFILYLRERPRLNTRSTRYGVSQTTINRTLSALSSLYKYLTEEVENEDGEPYFYRNVMKKVQTKKKSETLASRAENIKGK
LFLGDETQGFLDYIDNEYEKTLSNRARSSFFKNKERDLAIIALILASGIRLSEAVNVDLRDLNLITMVVEVTRKGGKRDA
VPYAPFAKTYFERYLEVRSQRYKTTAKDTAFFVTLYRDVPSRIDPSSVEKLVAKYSQAFKVRVTPHKLRHTLATRLYAQT
NSQVLVSNQLGHASTQVTDLYTHIINEEQKNALDNL

Sequences:

>Translated_356_residues
MKREQLIQNIEKLKHIMPSYVLEYYQSKLTIPYSLNTLYEYLKEYERFFSWLVDSGVADVDKITDVSLSVLENLTKRDLE
SFILYLRERPRLNTRSTRYGVSQTTINRTLSALSSLYKYLTEEVENEDGEPYFYRNVMKKVQTKKKSETLASRAENIKGK
LFLGDETQGFLDYIDNEYEKTLSNRARSSFFKNKERDLAIIALILASGIRLSEAVNVDLRDLNLITMVVEVTRKGGKRDA
VPYAPFAKTYFERYLEVRSQRYKTTAKDTAFFVTLYRDVPSRIDPSSVEKLVAKYSQAFKVRVTPHKLRHTLATRLYAQT
NSQVLVSNQLGHASTQVTDLYTHIINEEQKNALDNL
>Mature_356_residues
MKREQLIQNIEKLKHIMPSYVLEYYQSKLTIPYSLNTLYEYLKEYERFFSWLVDSGVADVDKITDVSLSVLENLTKRDLE
SFILYLRERPRLNTRSTRYGVSQTTINRTLSALSSLYKYLTEEVENEDGEPYFYRNVMKKVQTKKKSETLASRAENIKGK
LFLGDETQGFLDYIDNEYEKTLSNRARSSFFKNKERDLAIIALILASGIRLSEAVNVDLRDLNLITMVVEVTRKGGKRDA
VPYAPFAKTYFERYLEVRSQRYKTTAKDTAFFVTLYRDVPSRIDPSSVEKLVAKYSQAFKVRVTPHKLRHTLATRLYAQT
NSQVLVSNQLGHASTQVTDLYTHIINEEQKNALDNL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerS subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=253, Percent_Identity=28.0632411067194, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789261, Length=167, Percent_Identity=30.5389221556886, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERS_LACLA (Q9CG78)

Other databases:

- EMBL:   AE005176
- PIR:   H86778
- RefSeq:   NP_267388.1
- ProteinModelPortal:   Q9CG78
- GeneID:   1114882
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L57903
- NMPDR:   fig|272623.1.peg.1268
- HOGENOM:   HBG515070
- OMA:   YDDMRRE
- ProtClustDB:   PRK05084
- BioCyc:   LLAC272623:L57903-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01816
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 41398; Mature: 41398

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: ACT_SITE 210-210 ACT_SITE 234-234 ACT_SITE 306-306 ACT_SITE 309-309 ACT_SITE 332-332 ACT_SITE 341-341

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKREQLIQNIEKLKHIMPSYVLEYYQSKLTIPYSLNTLYEYLKEYERFFSWLVDSGVADV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHH
DKITDVSLSVLENLTKRDLESFILYLRERPRLNTRSTRYGVSQTTINRTLSALSSLYKYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHH
TEEVENEDGEPYFYRNVMKKVQTKKKSETLASRAENIKGKLFLGDETQGFLDYIDNEYEK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHH
TLSNRARSSFFKNKERDLAIIALILASGIRLSEAVNVDLRDLNLITMVVEVTRKGGKRDA
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
VPYAPFAKTYFERYLEVRSQRYKTTAKDTAFFVTLYRDVPSRIDPSSVEKLVAKYSQAFK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHE
VRVTPHKLRHTLATRLYAQTNSQVLVSNQLGHASTQVTDLYTHIINEEQKNALDNL
EEECHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCHHHHHHCCCC
>Mature Secondary Structure
MKREQLIQNIEKLKHIMPSYVLEYYQSKLTIPYSLNTLYEYLKEYERFFSWLVDSGVADV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHH
DKITDVSLSVLENLTKRDLESFILYLRERPRLNTRSTRYGVSQTTINRTLSALSSLYKYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHH
TEEVENEDGEPYFYRNVMKKVQTKKKSETLASRAENIKGKLFLGDETQGFLDYIDNEYEK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHH
TLSNRARSSFFKNKERDLAIIALILASGIRLSEAVNVDLRDLNLITMVVEVTRKGGKRDA
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
VPYAPFAKTYFERYLEVRSQRYKTTAKDTAFFVTLYRDVPSRIDPSSVEKLVAKYSQAFK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHE
VRVTPHKLRHTLATRLYAQTNSQVLVSNQLGHASTQVTDLYTHIINEEQKNALDNL
EEECHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471