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The map label for this gene is nadD

Identifier: 15673081

GI number: 15673081

Start: 1106612

End: 1107199

Strand: Reverse

Name: nadD

Synonym: L106374

Alternate gene names: 15673081

Gene position: 1107199-1106612 (Counterclockwise)

Preceding gene: 15673087

Following gene: 15673072

Centisome position: 46.8

GC content: 34.35

Gene sequence:

>588_bases
ATGGATAAAGGGAACAGAAAAAAAGTAGGTCTATTAGGAGGAAATTTTAATCCAATTCATCATGCTCATTTAATGATGGC
TGACCAAGTTGCCCAACAAATGAATTTGGATAAGGTATTACTAATGCCTGAAAATATTCCACCTCATGTCGATGAAAAAG
AAACCATTTCTGCAAAACATCGAGTTAAAATGCTTGAGTTAGCAATCAAAGAAAATCCTAGACTCGGTCTTGAGTTGATT
GAAATTGAACGTGGTGGAAAATCTTACAGTTATGACACGCTCAAACTCCTGACTGAAGCTAATCCTGATACCGATTATTA
TTTCATTATTGGTAGCGACATGGTGGAATATCTTCCCAAATGGTACAAAATTGATGAACTCCTAAAACTTGTGACATTCA
TTGCCTTAAGAAGAAAGGATACAATCTCCAAAAGTCCTTATCCTGTTACTTGGCTTGATGCTCCCTTGTTACCAATTTCT
AGTACAATGCTAAGGGAAATGTTTGCCAAAAATATTGAACCCACTTACTTCTTACCTCAAAACGTTATTGATTACATTAA
AACTGAAAAATTATATAAAAAAAGATGA

Upstream 100 bases:

>100_bases
TAGTCTTATAGATTGCGATGAGCTATGGTACAATATAAATTGACTGATTCAAAATATTGGTAGATTAAATAATTTCAAAA
ATTAAGGAGAAAGCCCCCTT

Downstream 100 bases:

>100_bases
CCCAGAGAGGTCATCTTTTTGTTTAAACTTCCAAATTTAGAACTTCTTGCGCATAAATGGATGAATTTCCATTCAAAACG
TAGGCAATTGTCATAATTGG

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MDKGNRKKVGLLGGNFNPIHHAHLMMADQVAQQMNLDKVLLMPENIPPHVDEKETISAKHRVKMLELAIKENPRLGLELI
EIERGGKSYSYDTLKLLTEANPDTDYYFIIGSDMVEYLPKWYKIDELLKLVTFIALRRKDTISKSPYPVTWLDAPLLPIS
STMLREMFAKNIEPTYFLPQNVIDYIKTEKLYKKR

Sequences:

>Translated_195_residues
MDKGNRKKVGLLGGNFNPIHHAHLMMADQVAQQMNLDKVLLMPENIPPHVDEKETISAKHRVKMLELAIKENPRLGLELI
EIERGGKSYSYDTLKLLTEANPDTDYYFIIGSDMVEYLPKWYKIDELLKLVTFIALRRKDTISKSPYPVTWLDAPLLPIS
STMLREMFAKNIEPTYFLPQNVIDYIKTEKLYKKR
>Mature_195_residues
MDKGNRKKVGLLGGNFNPIHHAHLMMADQVAQQMNLDKVLLMPENIPPHVDEKETISAKHRVKMLELAIKENPRLGLELI
EIERGGKSYSYDTLKLLTEANPDTDYYFIIGSDMVEYLPKWYKIDELLKLVTFIALRRKDTISKSPYPVTWLDAPLLPIS
STMLREMFAKNIEPTYFLPQNVIDYIKTEKLYKKR

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=209, Percent_Identity=30.622009569378, Blast_Score=100, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_LACLA (Q9CGJ7)

Other databases:

- EMBL:   AE005176
- PIR:   C86762
- RefSeq:   NP_267255.1
- ProteinModelPortal:   Q9CGJ7
- SMR:   Q9CGJ7
- GeneID:   1114739
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L106374
- NMPDR:   fig|272623.1.peg.1131
- HOGENOM:   HBG739448
- OMA:   TISAKHR
- ProtClustDB:   PRK00071
- BioCyc:   LLAC272623:L106374-MONOMER
- BRENDA:   2.7.7.18
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 22651; Mature: 22651

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKGNRKKVGLLGGNFNPIHHAHLMMADQVAQQMNLDKVLLMPENIPPHVDEKETISAKH
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHH
RVKMLELAIKENPRLGLELIEIERGGKSYSYDTLKLLTEANPDTDYYFIIGSDMVEYLPK
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHEECCCCCCCEEEEECCHHHHHCHH
WYKIDELLKLVTFIALRRKDTISKSPYPVTWLDAPLLPISSTMLREMFAKNIEPTYFLPQ
HCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCEECHH
NVIDYIKTEKLYKKR
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKGNRKKVGLLGGNFNPIHHAHLMMADQVAQQMNLDKVLLMPENIPPHVDEKETISAKH
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHH
RVKMLELAIKENPRLGLELIEIERGGKSYSYDTLKLLTEANPDTDYYFIIGSDMVEYLPK
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHEECCCCCCCEEEEECCHHHHHCHH
WYKIDELLKLVTFIALRRKDTISKSPYPVTWLDAPLLPISSTMLREMFAKNIEPTYFLPQ
HCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCEECHH
NVIDYIKTEKLYKKR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471