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The map label for this gene is comFA

Identifier: 15673072

GI number: 15673072

Start: 1096987

End: 1098309

Strand: Reverse

Name: comFA

Synonym: L0318

Alternate gene names: 15673072

Gene position: 1098309-1096987 (Counterclockwise)

Preceding gene: 15673081

Following gene: 15673071

Centisome position: 46.43

GC content: 33.56

Gene sequence:

>1323_bases
ATGAGCACTAATCAAGAAAAGTTATTTGGCCGTTTATTATTAAAAAATGATATTTTGCAACTTATAAAAAATACTGACAA
GATTTCTGTCAGTAAAATTTTTAGTAATTTTTTGTTAGAAACGAAGGTGAATCCAATTTTGGGAATGACTTCAATTTCTT
CCAATAAAATAAAATGCAACCGTTGTGGGACTGTTCATATAAAAAATTCTGTCAAACTTCCAATTGGTGTATTTTACTGT
CCAAGTTGTATTCAATTAGGTCGAGTCCGCTCCGATGATTTCTTGTACTTTCTGCCACAAAAGAATTTCCCAAAGAAATC
ATATATAAACTGGTCTGGAAAACTGACAGAGAATCAAAAATCAATTTCAAATGCCCTTTGTCAGGAAATTAATTCTCATC
AGCAAATAATTGTCCAAGCTGTGACTGGAGCTGGAAAAACTGAAATGATTTATCAAGTCATTGAGCAAATTTTAGAAAGC
GGTGGGGTTGTTGGTCTAGCTAGTCCAAGAATTGATGTTTGTCTTGAACTTCATCAGCGATTATCACGTGATTTTTCCTG
TAAGATTCCACTCTTATATCATGATGGCGACAGCTATTTCCGAGCTCCATTAATAATAATGACCAGTCATCAGCTTTTAC
GTTTCAAGGAAGCTTTTGATTTGCTGATTATTGATGAAGTTGATGCCTTTCCCTTTAGAGATAATGAAATGCTTTATGTT
GCGGCAGAAAAAGCAAGAAAAATAGAAGGAAATTTAATATATTTGACCGCAACTTCTACTGACAAACTTGAAAAAGATAT
AAAAAAGCAAAAACTCTATCCTTTGTTTCTCCCGCGTCGTTTTCACAATTTCCCTTTAGTGGTGCCTAAATTTTTTTGGA
AAAATAAATTTGATAAGAAATTAATTGAGCAAAGAAATAGTGGCTTTCCTCTTCTTATTTTTGCTGCTGAAATTGAATTT
GGACAAGAATTTGCAAAACAACTACAATTGAAATTTCCTAAAGAAAAAATTGCTTCCGTTGCTTCAACAACAAAAGATAG
ATTGGAAATTGTTAAAGCTTTTAGAAATAAAGAAATTACTATTTTAATAGCGACATCAATTCTTGAACGGGGAGTCACTT
TTCCAAATGTTGATGTTTTTGTCATCAACAGTGAGCACCCAAACTTCACTAAATCCGCACTGATACAAATGGCTGGACGT
GTGGGTCGTAGTCCTGAACGTCCAACAGGCTTAGTTAGTTTTTTTCATTACGGAAAATCCAAAGCAATGTGTCAGGCAGT
TAGAGAAATCAAAAAAATGAACCAACTGGGATGTTTTTCATGA

Upstream 100 bases:

>100_bases
ATTTCCTCTTCATTGATAAAATCAGTTTTTATAGTGATAGTCATGCTACTGATTTTAACAAATTTTGTTACATTTTAACA
GCATTTTCGTATAGAATAGT

Downstream 100 bases:

>100_bases
TAAAGTGTTTGCTTTGTTCAAGAAATATTGCTCAAAACTTTCTATTTAGTGAACTTTTCCTACTCAAAAGTCCTCAAAAT
CTTTTATGTTCTAAATGTCA

Product: ComFA

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSTNQEKLFGRLLLKNDILQLIKNTDKISVSKIFSNFLLETKVNPILGMTSISSNKIKCNRCGTVHIKNSVKLPIGVFYC
PSCIQLGRVRSDDFLYFLPQKNFPKKSYINWSGKLTENQKSISNALCQEINSHQQIIVQAVTGAGKTEMIYQVIEQILES
GGVVGLASPRIDVCLELHQRLSRDFSCKIPLLYHDGDSYFRAPLIIMTSHQLLRFKEAFDLLIIDEVDAFPFRDNEMLYV
AAEKARKIEGNLIYLTATSTDKLEKDIKKQKLYPLFLPRRFHNFPLVVPKFFWKNKFDKKLIEQRNSGFPLLIFAAEIEF
GQEFAKQLQLKFPKEKIASVASTTKDRLEIVKAFRNKEITILIATSILERGVTFPNVDVFVINSEHPNFTKSALIQMAGR
VGRSPERPTGLVSFFHYGKSKAMCQAVREIKKMNQLGCFS

Sequences:

>Translated_440_residues
MSTNQEKLFGRLLLKNDILQLIKNTDKISVSKIFSNFLLETKVNPILGMTSISSNKIKCNRCGTVHIKNSVKLPIGVFYC
PSCIQLGRVRSDDFLYFLPQKNFPKKSYINWSGKLTENQKSISNALCQEINSHQQIIVQAVTGAGKTEMIYQVIEQILES
GGVVGLASPRIDVCLELHQRLSRDFSCKIPLLYHDGDSYFRAPLIIMTSHQLLRFKEAFDLLIIDEVDAFPFRDNEMLYV
AAEKARKIEGNLIYLTATSTDKLEKDIKKQKLYPLFLPRRFHNFPLVVPKFFWKNKFDKKLIEQRNSGFPLLIFAAEIEF
GQEFAKQLQLKFPKEKIASVASTTKDRLEIVKAFRNKEITILIATSILERGVTFPNVDVFVINSEHPNFTKSALIQMAGR
VGRSPERPTGLVSFFHYGKSKAMCQAVREIKKMNQLGCFS
>Mature_439_residues
STNQEKLFGRLLLKNDILQLIKNTDKISVSKIFSNFLLETKVNPILGMTSISSNKIKCNRCGTVHIKNSVKLPIGVFYCP
SCIQLGRVRSDDFLYFLPQKNFPKKSYINWSGKLTENQKSISNALCQEINSHQQIIVQAVTGAGKTEMIYQVIEQILESG
GVVGLASPRIDVCLELHQRLSRDFSCKIPLLYHDGDSYFRAPLIIMTSHQLLRFKEAFDLLIIDEVDAFPFRDNEMLYVA
AEKARKIEGNLIYLTATSTDKLEKDIKKQKLYPLFLPRRFHNFPLVVPKFFWKNKFDKKLIEQRNSGFPLLIFAAEIEFG
QEFAKQLQLKFPKEKIASVASTTKDRLEIVKAFRNKEITILIATSILERGVTFPNVDVFVINSEHPNFTKSALIQMAGRV
GRSPERPTGLVSFFHYGKSKAMCQAVREIKKMNQLGCFS

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50234; Mature: 50103

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNQEKLFGRLLLKNDILQLIKNTDKISVSKIFSNFLLETKVNPILGMTSISSNKIKCN
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
RCGTVHIKNSVKLPIGVFYCPSCIQLGRVRSDDFLYFLPQKNFPKKSYINWSGKLTENQK
CCCEEEECCCCCCCEEEEECHHHHHHCCCCCCCEEEECCCCCCCCCCEECCCCCCCCHHH
SISNALCQEINSHQQIIVQAVTGAGKTEMIYQVIEQILESGGVVGLASPRIDVCLELHQR
HHHHHHHHHHCCHHHEEHHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHH
LSRDFSCKIPLLYHDGDSYFRAPLIIMTSHQLLRFKEAFDLLIIDEVDAFPFRDNEMLYV
HCCCCCCEEEEEEECCCCCCCCCEEEEECHHHHHHHHHHCEEEEECCCCCCCCCCCEEEE
AAEKARKIEGNLIYLTATSTDKLEKDIKKQKLYPLFLPRRFHNFPLVVPKFFWKNKFDKK
EECCCCCCCCCEEEEEECCHHHHHHHHHHHCCCEEECCHHHCCCCEEECHHHHCCCHHHH
LIEQRNSGFPLLIFAAEIEFGQEFAKQLQLKFPKEKIASVASTTKDRLEIVKAFRNKEIT
HHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
ILIATSILERGVTFPNVDVFVINSEHPNFTKSALIQMAGRVGRSPERPTGLVSFFHYGKS
EEEEHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCH
KAMCQAVREIKKMNQLGCFS
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
STNQEKLFGRLLLKNDILQLIKNTDKISVSKIFSNFLLETKVNPILGMTSISSNKIKCN
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
RCGTVHIKNSVKLPIGVFYCPSCIQLGRVRSDDFLYFLPQKNFPKKSYINWSGKLTENQK
CCCEEEECCCCCCCEEEEECHHHHHHCCCCCCCEEEECCCCCCCCCCEECCCCCCCCHHH
SISNALCQEINSHQQIIVQAVTGAGKTEMIYQVIEQILESGGVVGLASPRIDVCLELHQR
HHHHHHHHHHCCHHHEEHHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHH
LSRDFSCKIPLLYHDGDSYFRAPLIIMTSHQLLRFKEAFDLLIIDEVDAFPFRDNEMLYV
HCCCCCCEEEEEEECCCCCCCCCEEEEECHHHHHHHHHHCEEEEECCCCCCCCCCCEEEE
AAEKARKIEGNLIYLTATSTDKLEKDIKKQKLYPLFLPRRFHNFPLVVPKFFWKNKFDKK
EECCCCCCCCCEEEEEECCHHHHHHHHHHHCCCEEECCHHHCCCCEEECHHHHCCCHHHH
LIEQRNSGFPLLIFAAEIEFGQEFAKQLQLKFPKEKIASVASTTKDRLEIVKAFRNKEIT
HHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
ILIATSILERGVTFPNVDVFVINSEHPNFTKSALIQMAGRVGRSPERPTGLVSFFHYGKS
EEEEHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCH
KAMCQAVREIKKMNQLGCFS
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]