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The map label for this gene is copB

Identifier: 15672833

GI number: 15672833

Start: 871221

End: 873308

Strand: Reverse

Name: copB

Synonym: L70979

Alternate gene names: 15672833

Gene position: 873308-871221 (Counterclockwise)

Preceding gene: 15672863

Following gene: 15672818

Centisome position: 36.92

GC content: 37.36

Gene sequence:

>2088_bases
ATGTCAAATAAAACTCATTCGTCTAATCACGATGAAATGATGTCTGAGCATCATCATAATCATGAAATAATGGATATGGA
GCACGAAAACCATGAGATGCACAACATGCACAATATGGATAATATGCATGATATGGACAATATGGATATGATGAATCATG
GAGGACACATGATGCATATGGGTGATATGAGTAAAAAGCTCAAAGTGGCTATCATTCTTATGATTCCGCTACTACTCATT
TCACCAATCGCTGGCTTTACTATCCTTAAATTCCCCGGAAGTGAAATTTTGCAACTTATACTTGGTACAATTATCTTCTT
TTACTCTGGGACTCCTTTTTTTAGCGGAGCAAAAGGTGAATTAAAAAGCCGTAAGCCAGCCATGATGATGCTGATTACAA
TGGGAATTACCGTTGCCTATGCTTATTCTGTTTATGCCACAATTATGAGTCTTAACGGACATATGGGCATGAACTTCTGG
TTTGAACTGGCAACTTTAATTGTCATTATGTTGATTGGTCACCTGATTGAGATGAAAGCAATCATGGGTGCTGGCGATGC
ATTGAAAGATTTAGCAAGCCTTGTTCCCAAAAAAGCTCACTTAAAAAGTGGGAAGGATGTGGAGCTTTCAGAACTAAAAG
TTGGCGATTTGCTTTTAGTGAAAGAAAATGAAAAAATTCCTGCAGATGGCCTTATATTAAGTGAAGCGCTCGTTGATGAG
TCAATGATTACTGGTGAAAGCCGAGCAGTCAATAAAAAAACAAATGACCTTGTTTATGGTGGTTCCCTCAATCAAAACCA
ACCATTTGAGATGAAAGTCACAACCCTTGGAAAAGATTCATTTCTCAATCAAGTGGCCGAATTAGTCAAGAAAGCCCAAG
CTCAAAAATCTAATTTGGAAAATATGGCTGACAGAGTGGCTGGTTACCTTTTCTATGCTGCACTTATTGTCGGTATCTTC
TCATTAATTTTTTGGACAATTAGCTCTAACTTTAGTTTTGCTCTACTTCTTGCGGTTTCTGTTTTTGTAATTGCATGTCC
ACACGCTTTAGGTCTTGCGGTTCCACTTGTTGTTTCTCGCCTAACCAGTATTTCTGCTAAAAATGGTTTATTAATTCAAA
ACAGAACTTCTCTAGAAAAAATAAATACAATTAAATATGCCTTAATGGATAAAACGGGAACATTAACTGACGGTAAGTTT
ATTGTTCGTAATGTTATTGATTTTACTGATGAAACAGACATTCTCCAAATCATGGCAGCACTTGAAGGAAGTTCCACTCA
CCCGATTGCTCAATCAATCGTTGCAGCTGCTAAACCTCTTGGAAATCTAAAAGTTGAAGCGGTTGAAAATATTCCAGGAG
TTGGGATTAAAGGGCAAGTTAATCAAAACTTTTATCAAATTGTTAACTATAAATATCTTCGTGAAAATCAACTTTCTTAT
GATGAACAAAAGATTGCTCAATATTTAGATTTAGGTTTAACTGTATCTTTCCTAATCAATGAACAACAAGATGTTTTAGG
ATTTATTGCCTTAGGAGATTCTCCTAAAGCAGACGCGAAAGCCTTTATTAATGGTTTATTAGCCCAAGGAATTACCCCTG
TTATGCTCACGGGTGATAATAAAGAAACTGCTAAAAAAATTGCTAGTGCACTAAATATTCCCGAATTTAGAGCGGAATTA
AAACCTGAAGATAAAGCAGAAATTGTGAAAGAGTACCAAAAGAAAGCCGGCGTGCTTTTCATTGGTGATGGTGTCAATGA
TTCCCCAGCTCTTGCAACTGCTACGATTGGTTTTGCGATTGGAGCAGGAACTTCGGTTGCTATCAGTACCGCTGATGTCG
TCCTAGTTAACTCCAATCCAAGTGACGTCTTGGATATGATTAATATCTCCAAACGCATGCTTAGAAAAATGAAACAAAAC
CTCTGGTTTGGAGCAGGCTATAACATTATTGCTATTCCTGTTGCAGCGGGTATTCTTTATCCATTTACAGGGATTTATAT
TGACCCTCTCATTGCAGCAGTCCTGATGTCAATCTCAACCGTGATTGTCTCAATCAACGCGATGGGATTGAGGTATGATA
AAAAATAG

Upstream 100 bases:

>100_bases
TAATATTTATAGAATACAGCTTTTTTCCTTGACTTTGATAGTTTACAATTGTAAACTATATATAGATAGAAATTTCAAAG
CATTCATTTAGGAGGAAAAT

Downstream 100 bases:

>100_bases
AAGAGCCTATGCTCTTCTATTTTTTTATATTATTATTTAGTTAAAAAAATTATTTTATATTCTTTCTTCTATTGCCAACA
ACATCAGGATAGAGCTTTCG

Product: copper-potassium transporting ATPase B

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MSNKTHSSNHDEMMSEHHHNHEIMDMEHENHEMHNMHNMDNMHDMDNMDMMNHGGHMMHMGDMSKKLKVAIILMIPLLLI
SPIAGFTILKFPGSEILQLILGTIIFFYSGTPFFSGAKGELKSRKPAMMMLITMGITVAYAYSVYATIMSLNGHMGMNFW
FELATLIVIMLIGHLIEMKAIMGAGDALKDLASLVPKKAHLKSGKDVELSELKVGDLLLVKENEKIPADGLILSEALVDE
SMITGESRAVNKKTNDLVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQAQKSNLENMADRVAGYLFYAALIVGIF
SLIFWTISSNFSFALLLAVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGKF
IVRNVIDFTDETDILQIMAALEGSSTHPIAQSIVAAAKPLGNLKVEAVENIPGVGIKGQVNQNFYQIVNYKYLRENQLSY
DEQKIAQYLDLGLTVSFLINEQQDVLGFIALGDSPKADAKAFINGLLAQGITPVMLTGDNKETAKKIASALNIPEFRAEL
KPEDKAEIVKEYQKKAGVLFIGDGVNDSPALATATIGFAIGAGTSVAISTADVVLVNSNPSDVLDMINISKRMLRKMKQN
LWFGAGYNIIAIPVAAGILYPFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDKK

Sequences:

>Translated_695_residues
MSNKTHSSNHDEMMSEHHHNHEIMDMEHENHEMHNMHNMDNMHDMDNMDMMNHGGHMMHMGDMSKKLKVAIILMIPLLLI
SPIAGFTILKFPGSEILQLILGTIIFFYSGTPFFSGAKGELKSRKPAMMMLITMGITVAYAYSVYATIMSLNGHMGMNFW
FELATLIVIMLIGHLIEMKAIMGAGDALKDLASLVPKKAHLKSGKDVELSELKVGDLLLVKENEKIPADGLILSEALVDE
SMITGESRAVNKKTNDLVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQAQKSNLENMADRVAGYLFYAALIVGIF
SLIFWTISSNFSFALLLAVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGKF
IVRNVIDFTDETDILQIMAALEGSSTHPIAQSIVAAAKPLGNLKVEAVENIPGVGIKGQVNQNFYQIVNYKYLRENQLSY
DEQKIAQYLDLGLTVSFLINEQQDVLGFIALGDSPKADAKAFINGLLAQGITPVMLTGDNKETAKKIASALNIPEFRAEL
KPEDKAEIVKEYQKKAGVLFIGDGVNDSPALATATIGFAIGAGTSVAISTADVVLVNSNPSDVLDMINISKRMLRKMKQN
LWFGAGYNIIAIPVAAGILYPFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDKK
>Mature_694_residues
SNKTHSSNHDEMMSEHHHNHEIMDMEHENHEMHNMHNMDNMHDMDNMDMMNHGGHMMHMGDMSKKLKVAIILMIPLLLIS
PIAGFTILKFPGSEILQLILGTIIFFYSGTPFFSGAKGELKSRKPAMMMLITMGITVAYAYSVYATIMSLNGHMGMNFWF
ELATLIVIMLIGHLIEMKAIMGAGDALKDLASLVPKKAHLKSGKDVELSELKVGDLLLVKENEKIPADGLILSEALVDES
MITGESRAVNKKTNDLVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQAQKSNLENMADRVAGYLFYAALIVGIFS
LIFWTISSNFSFALLLAVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGKFI
VRNVIDFTDETDILQIMAALEGSSTHPIAQSIVAAAKPLGNLKVEAVENIPGVGIKGQVNQNFYQIVNYKYLRENQLSYD
EQKIAQYLDLGLTVSFLINEQQDVLGFIALGDSPKADAKAFINGLLAQGITPVMLTGDNKETAKKIASALNIPEFRAELK
PEDKAEIVKEYQKKAGVLFIGDGVNDSPALATATIGFAIGAGTSVAISTADVVLVNSNPSDVLDMINISKRMLRKMKQNL
WFGAGYNIIAIPVAAGILYPFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDKK

Specific function: Involved in copper export. Can also export silver [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=667, Percent_Identity=31.1844077961019, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI115529486, Length=676, Percent_Identity=29.7337278106509, Blast_Score=272, Evalue=1e-72,
Organism=Homo sapiens, GI55743073, Length=515, Percent_Identity=32.2330097087379, Blast_Score=227, Evalue=3e-59,
Organism=Homo sapiens, GI48762687, Length=246, Percent_Identity=25.2032520325203, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI48762691, Length=246, Percent_Identity=25.2032520325203, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI48762689, Length=246, Percent_Identity=25.2032520325203, Blast_Score=70, Evalue=9e-12,
Organism=Homo sapiens, GI48762685, Length=246, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI118498343, Length=238, Percent_Identity=26.0504201680672, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1786691, Length=645, Percent_Identity=32.2480620155039, Blast_Score=292, Evalue=5e-80,
Organism=Escherichia coli, GI1789879, Length=566, Percent_Identity=31.4487632508834, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1786914, Length=460, Percent_Identity=29.3478260869565, Blast_Score=136, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17556548, Length=667, Percent_Identity=29.9850074962519, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71997275, Length=603, Percent_Identity=23.5489220563847, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71997262, Length=603, Percent_Identity=23.5489220563847, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71997269, Length=559, Percent_Identity=23.9713774597496, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17554158, Length=176, Percent_Identity=27.8409090909091, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193210130, Length=176, Percent_Identity=27.8409090909091, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71988506, Length=176, Percent_Identity=27.8409090909091, Blast_Score=73, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320475, Length=723, Percent_Identity=31.2586445366528, Blast_Score=285, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6319772, Length=677, Percent_Identity=29.0989660265879, Blast_Score=236, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6325221, Length=564, Percent_Identity=21.8085106382979, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321430, Length=557, Percent_Identity=23.1597845601436, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321432, Length=236, Percent_Identity=26.6949152542373, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221329854, Length=441, Percent_Identity=31.0657596371882, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24668696, Length=232, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281366617, Length=232, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668704, Length=232, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668708, Length=232, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI161085803, Length=232, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24762455, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762453, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762447, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762457, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762449, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762445, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762451, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136664, Length=194, Percent_Identity=29.8969072164948, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 75983; Mature: 75852

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKTHSSNHDEMMSEHHHNHEIMDMEHENHEMHNMHNMDNMHDMDNMDMMNHGGHMMHM
CCCCCCCCCHHHHHHHHCCCCCEECCCCCCCHHHHHCCCCCCCCCCCCHHHHCCCCEEEE
GDMSKKLKVAIILMIPLLLISPIAGFTILKFPGSEILQLILGTIIFFYSGTPFFSGAKGE
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
LKSRKPAMMMLITMGITVAYAYSVYATIMSLNGHMGMNFWFELATLIVIMLIGHLIEMKA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IMGAGDALKDLASLVPKKAHLKSGKDVELSELKVGDLLLVKENEKIPADGLILSEALVDE
HHCCCHHHHHHHHHCCCHHHCCCCCCCCHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHH
SMITGESRAVNKKTNDLVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQAQKSNLE
HHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
NMADRVAGYLFYAALIVGIFSLIFWTISSNFSFALLLAVSVFVIACPHALGLAVPLVVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGKFIVRNVIDFTDETDILQIMAA
HHHHCCCCCEEEECCCHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
LEGSSTHPIAQSIVAAAKPLGNLKVEAVENIPGVGIKGQVNQNFYQIVNYKYLRENQLSY
HCCCCCCHHHHHHHHHHCCCCCEEEEEHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
DEQKIAQYLDLGLTVSFLINEQQDVLGFIALGDSPKADAKAFINGLLAQGITPVMLTGDN
CHHHHHHHHHCCCEEEEEECCCCHHEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCC
KETAKKIASALNIPEFRAELKPEDKAEIVKEYQKKAGVLFIGDGVNDSPALATATIGFAI
HHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHC
GAGTSVAISTADVVLVNSNPSDVLDMINISKRMLRKMKQNLWFGAGYNIIAIPVAAGILY
CCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCEEEHHHHHHHHH
PFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCC
>Mature Secondary Structure 
SNKTHSSNHDEMMSEHHHNHEIMDMEHENHEMHNMHNMDNMHDMDNMDMMNHGGHMMHM
CCCCCCCCHHHHHHHHCCCCCEECCCCCCCHHHHHCCCCCCCCCCCCHHHHCCCCEEEE
GDMSKKLKVAIILMIPLLLISPIAGFTILKFPGSEILQLILGTIIFFYSGTPFFSGAKGE
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
LKSRKPAMMMLITMGITVAYAYSVYATIMSLNGHMGMNFWFELATLIVIMLIGHLIEMKA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IMGAGDALKDLASLVPKKAHLKSGKDVELSELKVGDLLLVKENEKIPADGLILSEALVDE
HHCCCHHHHHHHHHCCCHHHCCCCCCCCHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHH
SMITGESRAVNKKTNDLVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQAQKSNLE
HHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
NMADRVAGYLFYAALIVGIFSLIFWTISSNFSFALLLAVSVFVIACPHALGLAVPLVVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGKFIVRNVIDFTDETDILQIMAA
HHHHCCCCCEEEECCCHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
LEGSSTHPIAQSIVAAAKPLGNLKVEAVENIPGVGIKGQVNQNFYQIVNYKYLRENQLSY
HCCCCCCHHHHHHHHHHCCCCCEEEEEHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
DEQKIAQYLDLGLTVSFLINEQQDVLGFIALGDSPKADAKAFINGLLAQGITPVMLTGDN
CHHHHHHHHHCCCEEEEEECCCCHHEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCC
KETAKKIASALNIPEFRAELKPEDKAEIVKEYQKKAGVLFIGDGVNDSPALATATIGFAI
HHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHC
GAGTSVAISTADVVLVNSNPSDVLDMINISKRMLRKMKQNLWFGAGYNIIAIPVAAGILY
CCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCEEEHHHHHHHHH
PFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8048974; 2953719 [H]