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The map label for this gene is yibG

Identifier: 15672791

GI number: 15672791

Start: 818598

End: 819938

Strand: Reverse

Name: yibG

Synonym: L18622

Alternate gene names: 15672791

Gene position: 819938-818598 (Counterclockwise)

Preceding gene: 15672804

Following gene: 15672773

Centisome position: 34.66

GC content: 36.17

Gene sequence:

>1341_bases
TTGGAAACTAATCAATCCTTAAAGAAAAAAATGGCCGCACGCCATATTACTATGATTGCTCTTGGTGGAGCAATTGGTGC
TGGTCTTTTCAAAGGAAGCTCATCAGCCATTGCTGCCGCTGGTCCCTCTGTCTTAATCGCTTATTTTATCGGAGGAATCG
TTCTTTATTTTGTAATGAAGAGTTTAGAAAAGCTTGTTCTAAGTTCAAAAGATCCACACGGCTTGTCCGGACTTGTTCAG
CCTTATCTGGGTAATCATACGGCTGATTTTACGGACTGGGTTTATTGGTCAATGTGGATGATTAATATCATTGCTGAGGC
TGTTGCTGCTGCAAGTTTTTTGCAGCTCTGGTTTGCTAATGTTCCCACTTGGGTTTTTGTCTTGATTATTGCCCTTTTAA
CTTCCCTTATTAACTTATTCTCAGTTGCTCTCTTTGCTGAGACAGAATACTGGTTGGCATTTATTAAAATTAGTGTTGTT
ATTTTGTTGATTATTTTTGGTGTTTTTCTTGTGGCAAAACAAATTTTTGATACTAATCTAGTGACTACTTTCTCTGGAAT
GACCGCTCATGGTGGCTTTGCTCCTCATGGCTTTAAAGGGGTCATTAATTCTTTATTAATTGTTATCTATTCGTATGGTG
GTTCTGAATTAATTGCTATTACAGTTAGTGAAACAGAAGATCCTAAAAGAGCCATTCCTAAAGCCATCCGCGGTGTAATC
GGGCGAATTATTTCATTTTATATTATTCCGATGTTCTTACTTCTTGTGATTTATAATTGGCAAACGTTGGCTACTTCTTC
AATGAGCCCTTTTGTGATGGTCTTTAATAAAATGCATATTCCTTTTGCTGGCGATATTGTCAACTTGATTATCATTCTTG
CCCTCTTCTCATCAATTAATTCTGGAATCTATGCTTCATCTCGCCTTTTGTATTTCCGTTTAAAAAATCGTCAAGGTAAA
ATGGCTCAAAGAATGGCTCATTTAAATAAACATCACGTTCCTCAAAGAGCAGTTATTTTCTGTTCAGGTACACTTTATAT
CGGTGTTGTTCTTTCTTATTTTGTCGGTGATCGTTTGTTTAATTACTTGGCTGGTTCCCTTTCTTACACTGTTTTAGCCG
TTTGGATTTTAATTAGTCTCGCTGGTTTTGGTCTCTCTCTTAAAACAAAATCATTATCCGGTAGAACAATGAGTCTCTTA
GCACTGATTGCTCTCTTTCTCATTCTGATTGGTATTTTATTTACTAATCCAATTGGTGTGACTGTCTTCACAGCAATTCT
TTATTTCATCATCTTTATCAGTTATCAAAAAAAGAATGATTCTGTCAGTAATTTAAACTAA

Upstream 100 bases:

>100_bases
ACGTCCTCAGGACGTCTTTTTTTAATGTTTTATTATCAATTTATTAGTCAATAAAAGAGAGACGTCTCTGCTTATTGATT
TAGAAAGCTAGGAATTATCG

Downstream 100 bases:

>100_bases
TAAAAAAGACTTGATAATTAATCAAGTCTTTTTGTTTTTACTGACAGAATTATCTGTCAGTATTTTTTTGCTCAAAAGAT
TTTTGAACAAAATAACCAGA

Product: amino acid permease

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
METNQSLKKKMAARHITMIALGGAIGAGLFKGSSSAIAAAGPSVLIAYFIGGIVLYFVMKSLEKLVLSSKDPHGLSGLVQ
PYLGNHTADFTDWVYWSMWMINIIAEAVAAASFLQLWFANVPTWVFVLIIALLTSLINLFSVALFAETEYWLAFIKISVV
ILLIIFGVFLVAKQIFDTNLVTTFSGMTAHGGFAPHGFKGVINSLLIVIYSYGGSELIAITVSETEDPKRAIPKAIRGVI
GRIISFYIIPMFLLLVIYNWQTLATSSMSPFVMVFNKMHIPFAGDIVNLIIILALFSSINSGIYASSRLLYFRLKNRQGK
MAQRMAHLNKHHVPQRAVIFCSGTLYIGVVLSYFVGDRLFNYLAGSLSYTVLAVWILISLAGFGLSLKTKSLSGRTMSLL
ALIALFLILIGILFTNPIGVTVFTAILYFIIFISYQKKNDSVSNLN

Sequences:

>Translated_446_residues
METNQSLKKKMAARHITMIALGGAIGAGLFKGSSSAIAAAGPSVLIAYFIGGIVLYFVMKSLEKLVLSSKDPHGLSGLVQ
PYLGNHTADFTDWVYWSMWMINIIAEAVAAASFLQLWFANVPTWVFVLIIALLTSLINLFSVALFAETEYWLAFIKISVV
ILLIIFGVFLVAKQIFDTNLVTTFSGMTAHGGFAPHGFKGVINSLLIVIYSYGGSELIAITVSETEDPKRAIPKAIRGVI
GRIISFYIIPMFLLLVIYNWQTLATSSMSPFVMVFNKMHIPFAGDIVNLIIILALFSSINSGIYASSRLLYFRLKNRQGK
MAQRMAHLNKHHVPQRAVIFCSGTLYIGVVLSYFVGDRLFNYLAGSLSYTVLAVWILISLAGFGLSLKTKSLSGRTMSLL
ALIALFLILIGILFTNPIGVTVFTAILYFIIFISYQKKNDSVSNLN
>Mature_446_residues
METNQSLKKKMAARHITMIALGGAIGAGLFKGSSSAIAAAGPSVLIAYFIGGIVLYFVMKSLEKLVLSSKDPHGLSGLVQ
PYLGNHTADFTDWVYWSMWMINIIAEAVAAASFLQLWFANVPTWVFVLIIALLTSLINLFSVALFAETEYWLAFIKISVV
ILLIIFGVFLVAKQIFDTNLVTTFSGMTAHGGFAPHGFKGVINSLLIVIYSYGGSELIAITVSETEDPKRAIPKAIRGVI
GRIISFYIIPMFLLLVIYNWQTLATSSMSPFVMVFNKMHIPFAGDIVNLIIILALFSSINSGIYASSRLLYFRLKNRQGK
MAQRMAHLNKHHVPQRAVIFCSGTLYIGVVLSYFVGDRLFNYLAGSLSYTVLAVWILISLAGFGLSLKTKSLSGRTMSLL
ALIALFLILIGILFTNPIGVTVFTAILYFIIFISYQKKNDSVSNLN

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786302, Length=382, Percent_Identity=34.2931937172775, Blast_Score=237, Evalue=9e-64,
Organism=Escherichia coli, GI48994972, Length=440, Percent_Identity=33.6363636363636, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1786789, Length=406, Percent_Identity=33.2512315270936, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1790653, Length=351, Percent_Identity=34.4729344729345, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1786602, Length=454, Percent_Identity=33.2599118942731, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87081915, Length=378, Percent_Identity=33.0687830687831, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1789017, Length=377, Percent_Identity=31.2997347480106, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI87081708, Length=424, Percent_Identity=33.2547169811321, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1788480, Length=343, Percent_Identity=35.2769679300292, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324061, Length=420, Percent_Identity=28.8095238095238, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320772, Length=417, Percent_Identity=28.7769784172662, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6319824, Length=463, Percent_Identity=28.9416846652268, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6324059, Length=459, Percent_Identity=28.7581699346405, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324990, Length=405, Percent_Identity=29.8765432098765, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324924, Length=375, Percent_Identity=30.1333333333333, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322892, Length=324, Percent_Identity=30.8641975308642, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321053, Length=411, Percent_Identity=26.0340632603406, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324553, Length=408, Percent_Identity=28.6764705882353, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320717, Length=460, Percent_Identity=27.3913043478261, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320251, Length=437, Percent_Identity=24.2562929061785, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321629, Length=462, Percent_Identity=25.1082251082251, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322967, Length=410, Percent_Identity=27.5609756097561, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6319542, Length=432, Percent_Identity=24.0740740740741, Blast_Score=119, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6319543, Length=414, Percent_Identity=28.0193236714976, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324981, Length=430, Percent_Identity=27.6744186046512, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319608, Length=349, Percent_Identity=23.2091690544413, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49025; Mature: 49025

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNQSLKKKMAARHITMIALGGAIGAGLFKGSSSAIAAAGPSVLIAYFIGGIVLYFVMK
CCCCHHHHHHHHHHHHHHHEECHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
SLEKLVLSSKDPHGLSGLVQPYLGNHTADFTDWVYWSMWMINIIAEAVAAASFLQLWFAN
HHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPTWVFVLIIALLTSLINLFSVALFAETEYWLAFIKISVVILLIIFGVFLVAKQIFDTNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VTTFSGMTAHGGFAPHGFKGVINSLLIVIYSYGGSELIAITVSETEDPKRAIPKAIRGVI
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
GRIISFYIIPMFLLLVIYNWQTLATSSMSPFVMVFNKMHIPFAGDIVNLIIILALFSSIN
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
SGIYASSRLLYFRLKNRQGKMAQRMAHLNKHHVPQRAVIFCSGTLYIGVVLSYFVGDRLF
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHH
NYLAGSLSYTVLAVWILISLAGFGLSLKTKSLSGRTMSLLALIALFLILIGILFTNPIGV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
TVFTAILYFIIFISYQKKNDSVSNLN
HHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
METNQSLKKKMAARHITMIALGGAIGAGLFKGSSSAIAAAGPSVLIAYFIGGIVLYFVMK
CCCCHHHHHHHHHHHHHHHEECHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
SLEKLVLSSKDPHGLSGLVQPYLGNHTADFTDWVYWSMWMINIIAEAVAAASFLQLWFAN
HHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPTWVFVLIIALLTSLINLFSVALFAETEYWLAFIKISVVILLIIFGVFLVAKQIFDTNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VTTFSGMTAHGGFAPHGFKGVINSLLIVIYSYGGSELIAITVSETEDPKRAIPKAIRGVI
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
GRIISFYIIPMFLLLVIYNWQTLATSSMSPFVMVFNKMHIPFAGDIVNLIIILALFSSIN
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
SGIYASSRLLYFRLKNRQGKMAQRMAHLNKHHVPQRAVIFCSGTLYIGVVLSYFVGDRLF
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHH
NYLAGSLSYTVLAVWILISLAGFGLSLKTKSLSGRTMSLLALIALFLILIGILFTNPIGV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
TVFTAILYFIIFISYQKKNDSVSNLN
HHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]