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The map label for this gene is tig

Identifier: 15672533

GI number: 15672533

Start: 535867

End: 537150

Strand: Direct

Name: tig

Synonym: L0336

Alternate gene names: 15672533

Gene position: 535867-537150 (Clockwise)

Preceding gene: 15672532

Following gene: 15672534

Centisome position: 22.65

GC content: 36.45

Gene sequence:

>1284_bases
ATGACTGTAAGTTTTGAAAAAACTAGTGATACTAAAGGTACACTCTCATTTTCAATTGACCAAGAAACAATTAAAACTGG
GCTTGACAAAGCCTTTAATAAAGTAAAAGCTAACATTAGCGTTCCTGGTTTCCGTAAAGGTAAAATCAGCCGTCAAATGT
TTAATAAAATGTACGGTGAAGAAGCACTTTTTGAAGAAGCTTTAAACGCTGTTCTTCCAACTGCTTATGATGCAGCTGTA
AAAGAAGCTGGTATCGAACCAGTTGCACAACCAAAAATTGATGTTGCAAAAATGGAAAAAGGTTCTGACTGGGAATTGAC
TGCAGAAGTTGTTGTAAAACCAACCGTTTCACTTGGTGACTACAAAGACCTTACAGTTGAAGTAGAAGCAACAAAAGAAG
TTTCTGACGAAGAAGTTGAAACACGCTTGACTAACTCTCAAAACAATTTAGCTGAACTTGTAGTAAAAGAAACTGCTGCT
GAAAATGGTGATACTGTTGTTATTGACTTCGTTGGTTCAGTTGATGGTGTTGAATTTGAAGGTGGAAAAGGTTCTAACCA
CAGTCTTGAACTTGGTTCAGGTCAATTCATTCCAGGATTTGAAGAACAACTTGTTGGAACTAAAGCTGGTGAAACTGTAG
AAGTTAAAGTTACATTCCCAGAAAACTATCAAGCTGAAGACCTTGCTGGTAAAGAAGCACTCTTTGTTACAACTGTTAAT
GAAGTAAAAGCAAAAGAATTACCAGAACTTGATGATGAACTTGCTAAAGATATTGACGAAGAAGTTGAAACTTTGGATGA
GCTTAAAGCTAAATTCCGTAAAGAACTTGAAGAATCAAAAGCAGAAGCTTATAATGATGCTGTAGAAACTGCTGCAATCG
AAGCTGCTGTTGCCAATGCTGAAATCAAAGAAATTCCAGAAGAAATGATTCACGAAGAAGTTCATCGCGCTATGAACGAA
TTTCTTGGTGGAATGCAACAACAAGGAATCTCTCCAGAAATGTACTTCCAAATTACTGGAACTTCTGAAGATGATCTTCA
TAAACAATATGAAGCAGACGCTGACAAACGCGTGCGTACAAACTTGGTAATCGAAGCAATTGCTGCTGCTGAAAACTTTA
CAACTTCAGATGAAGAAGTTAAAGCAGAAATTGAAGATCTTGCTGGTCAATACAACATGCCTGTTGAACAAGTTGAAAAA
CTTCTTCCAGTTGATATGCTTAAACATGATATTGCAATGAAAAAAGCAGTGGAAGTTATTGCAACAACAGCAAAAGTAAA
ATAA

Upstream 100 bases:

>100_bases
ATAAGTCAAAAAAGCTAGTCTTTCTTGAAATATAGCGGATTTTATGCTATTCTTGAAATGTATGAATTTCTGAGCTCAGG
CTCAAAATAAGGAGAAAAAA

Downstream 100 bases:

>100_bases
TTTCATATAATAATGATAAAAAAATAAGTGTCAGTAACTACTGGTACTTATTTTTTTATTATTAATTCGAATTTTGAGTG
AGATTTAGTTCATGGATTTA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MTVSFEKTSDTKGTLSFSIDQETIKTGLDKAFNKVKANISVPGFRKGKISRQMFNKMYGEEALFEEALNAVLPTAYDAAV
KEAGIEPVAQPKIDVAKMEKGSDWELTAEVVVKPTVSLGDYKDLTVEVEATKEVSDEEVETRLTNSQNNLAELVVKETAA
ENGDTVVIDFVGSVDGVEFEGGKGSNHSLELGSGQFIPGFEEQLVGTKAGETVEVKVTFPENYQAEDLAGKEALFVTTVN
EVKAKELPELDDELAKDIDEEVETLDELKAKFRKELEESKAEAYNDAVETAAIEAAVANAEIKEIPEEMIHEEVHRAMNE
FLGGMQQQGISPEMYFQITGTSEDDLHKQYEADADKRVRTNLVIEAIAAAENFTTSDEEVKAEIEDLAGQYNMPVEQVEK
LLPVDMLKHDIAMKKAVEVIATTAKVK

Sequences:

>Translated_427_residues
MTVSFEKTSDTKGTLSFSIDQETIKTGLDKAFNKVKANISVPGFRKGKISRQMFNKMYGEEALFEEALNAVLPTAYDAAV
KEAGIEPVAQPKIDVAKMEKGSDWELTAEVVVKPTVSLGDYKDLTVEVEATKEVSDEEVETRLTNSQNNLAELVVKETAA
ENGDTVVIDFVGSVDGVEFEGGKGSNHSLELGSGQFIPGFEEQLVGTKAGETVEVKVTFPENYQAEDLAGKEALFVTTVN
EVKAKELPELDDELAKDIDEEVETLDELKAKFRKELEESKAEAYNDAVETAAIEAAVANAEIKEIPEEMIHEEVHRAMNE
FLGGMQQQGISPEMYFQITGTSEDDLHKQYEADADKRVRTNLVIEAIAAAENFTTSDEEVKAEIEDLAGQYNMPVEQVEK
LLPVDMLKHDIAMKKAVEVIATTAKVK
>Mature_426_residues
TVSFEKTSDTKGTLSFSIDQETIKTGLDKAFNKVKANISVPGFRKGKISRQMFNKMYGEEALFEEALNAVLPTAYDAAVK
EAGIEPVAQPKIDVAKMEKGSDWELTAEVVVKPTVSLGDYKDLTVEVEATKEVSDEEVETRLTNSQNNLAELVVKETAAE
NGDTVVIDFVGSVDGVEFEGGKGSNHSLELGSGQFIPGFEEQLVGTKAGETVEVKVTFPENYQAEDLAGKEALFVTTVNE
VKAKELPELDDELAKDIDEEVETLDELKAKFRKELEESKAEAYNDAVETAAIEAAVANAEIKEIPEEMIHEEVHRAMNEF
LGGMQQQGISPEMYFQITGTSEDDLHKQYEADADKRVRTNLVIEAIAAAENFTTSDEEVKAEIEDLAGQYNMPVEQVEKL
LPVDMLKHDIAMKKAVEVIATTAKVK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=436, Percent_Identity=31.8807339449541, Blast_Score=178, Evalue=7e-46,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_LACLA (Q9CI15)

Other databases:

- EMBL:   AE005176
- PIR:   G86693
- RefSeq:   NP_266707.1
- ProteinModelPortal:   Q9CI15
- GeneID:   1114170
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0336
- NMPDR:   fig|272623.1.peg.566
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   PRK01490
- BioCyc:   LLAC272623:L0336-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 46931; Mature: 46800

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSFEKTSDTKGTLSFSIDQETIKTGLDKAFNKVKANISVPGFRKGKISRQMFNKMYGE
CEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCH
EALFEEALNAVLPTAYDAAVKEAGIEPVAQPKIDVAKMEKGSDWELTAEVVVKPTVSLGD
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCEEEEEEEEECCCCCCC
YKDLTVEVEATKEVSDEEVETRLTNSQNNLAELVVKETAAENGDTVVIDFVGSVDGVEFE
CCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEC
GGKGSNHSLELGSGQFIPGFEEQLVGTKAGETVEVKVTFPENYQAEDLAGKEALFVTTVN
CCCCCCCEEECCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCCCEEEEEEHH
EVKAKELPELDDELAKDIDEEVETLDELKAKFRKELEESKAEAYNDAVETAAIEAAVANA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EIKEIPEEMIHEEVHRAMNEFLGGMQQQGISPEMYFQITGTSEDDLHKQYEADADKRVRT
HHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHH
NLVIEAIAAAENFTTSDEEVKAEIEDLAGQYNMPVEQVEKLLPVDMLKHDIAMKKAVEVI
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
ATTAKVK
HHHHCCC
>Mature Secondary Structure 
TVSFEKTSDTKGTLSFSIDQETIKTGLDKAFNKVKANISVPGFRKGKISRQMFNKMYGE
EECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCH
EALFEEALNAVLPTAYDAAVKEAGIEPVAQPKIDVAKMEKGSDWELTAEVVVKPTVSLGD
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCEEEEEEEEECCCCCCC
YKDLTVEVEATKEVSDEEVETRLTNSQNNLAELVVKETAAENGDTVVIDFVGSVDGVEFE
CCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEC
GGKGSNHSLELGSGQFIPGFEEQLVGTKAGETVEVKVTFPENYQAEDLAGKEALFVTTVN
CCCCCCCEEECCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCCCEEEEEEHH
EVKAKELPELDDELAKDIDEEVETLDELKAKFRKELEESKAEAYNDAVETAAIEAAVANA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EIKEIPEEMIHEEVHRAMNEFLGGMQQQGISPEMYFQITGTSEDDLHKQYEADADKRVRT
HHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHH
NLVIEAIAAAENFTTSDEEVKAEIEDLAGQYNMPVEQVEKLLPVDMLKHDIAMKKAVEVI
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
ATTAKVK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471