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The map label for this gene is llrC

Identifier: 15672379

GI number: 15672379

Start: 402989

End: 403690

Strand: Reverse

Name: llrC

Synonym: L0125

Alternate gene names: 15672379

Gene position: 403690-402989 (Counterclockwise)

Preceding gene: 15672385

Following gene: 15672378

Centisome position: 17.07

GC content: 38.6

Gene sequence:

>702_bases
ATGAAAAAAATTCTTGTTGTTGATGATGAAAAACCAATCTCAGATATCGTAAAATTTAATTTAACCAAAGAAGGTTTTGA
AGTCTTTACAGCTTTTGATGGTGAAGAAGCTCTTGAAGCATTTAAAGAAGTACAACCTGACCTTATTCTGCTTGATTTGA
TGTTACCTAAACTTGATGGTCTTGATGTTGCACGTGAAATCCGTAAAACTTCTGACACTCCAATTATTATGGTGTCAGCT
AAAGATAGTGAATTTGACAAAGTAATTGGTCTTGAACTTGGTGCTGATGATTATGTCACAAAACCATTCTCAAACCGTGA
ACTATTAGCTCGTATTAAAGCAAACTTGCGTCGTATCAATGTCGCACCTGCTGAATCTACTGACAATGTCAAGAAAGAAT
TGATTATCGGAAACCTCCGTATCAATCCAGCACACTATGCGGCTTATAAAAATGATAAACAACTCGACCTTACACACCGT
GAGTTTGAATTGCTTTACTACCTTGCTCAACACCTTGGCGAAGTGATCACTCGTGAAAACCTTTTGGAAACCGTTTGGGG
TTATGACTACTTTGGAGATGTTCGTACAGTTGACGTTACTGTTCGTCGTTTACGTGAAAAAGTTGAAGATACTCCAAGCC
GTCCACAATACGTTTCAACACGCCGCGGGGTTGGCTACTACATGAGCAACCCACATGATTAA

Upstream 100 bases:

>100_bases
TAAAAATTGTATAATATAACTGAAACAGCTTACTTGATTTGTTAATTCAAATAAATACGAGTAACATTCAATAAAAAATT
TTCCACTTGAAAGGACAACT

Downstream 100 bases:

>100_bases
ATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAGTTTTGATT
ACAATTTTGCTCATTTAAGT

Product: two-component system regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDGLDVAREIRKTSDTPIIMVSA
KDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRINVAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHR
EFELLYYLAQHLGEVITRENLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD

Sequences:

>Translated_233_residues
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDGLDVAREIRKTSDTPIIMVSA
KDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRINVAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHR
EFELLYYLAQHLGEVITRENLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD
>Mature_233_residues
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDGLDVAREIRKTSDTPIIMVSA
KDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRINVAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHR
EFELLYYLAQHLGEVITRENLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=44.1048034934498, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=40.0862068965517, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=39.9122807017544, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=36.6071428571429, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=39.5555555555556, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=35.6521739130435, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=34.9557522123894, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=35.3982300884956, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI145693140, Length=244, Percent_Identity=30.327868852459, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=34.051724137931, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=33.4782608695652, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=33.7719298245614, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.6521739130435, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=32.4786324786325, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=35.7798165137615, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26766; Mature: 26766

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG
CCEEEEECCCCCHHHHHHHCCCHHCEEEEEECCCHHHHHHHHHCCCCEEEEEHHHCCCCC
LDVAREIRKTSDTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRIN
HHHHHHHHHCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEE
VAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITREN
CCCCCCCCHHHHHHEEECEEECCHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
LLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG
CCEEEEECCCCCHHHHHHHCCCHHCEEEEEECCCHHHHHHHHHCCCCEEEEEHHHCCCCC
LDVAREIRKTSDTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRIN
HHHHHHHHHCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEE
VAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITREN
CCCCCCCCHHHHHHEEECEEECCHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
LLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]