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The map label for this gene is groES

Identifier: 15672375

GI number: 15672375

Start: 398525

End: 398809

Strand: Direct

Name: groES

Synonym: L198515

Alternate gene names: 15672375

Gene position: 398525-398809 (Clockwise)

Preceding gene: 15672374

Following gene: 15672376

Centisome position: 16.85

GC content: 38.25

Gene sequence:

>285_bases
ATGTTGAAACCTTTAGAGAATCGCGTAGTTTTACGTGTAAAAGAAGAAGAGGAAAAATCAATGGGTGGAATTGTGTTAAC
AAGCGCTTCCCAAGAAAAACCTCAAACAGCTGAAGTTGTTGCCGTCGGTGAAGGGAAAACAAATCATCATGGAACACTGA
TTTCTCCACTCGTAAAAGTAGGGGACACAGTAATTTTTGAAAAATTTGCTGGAACGACCGTAAAAATGGATGGTGAAGAA
TTCTTGATTCTCAAAGATTCAGACCTTCTTGCAATTGTAGAGTAA

Upstream 100 bases:

>100_bases
ATGTTTTCTCTTGACTAAATCTGACCATTGAGATAAAATAAGAATATGTTAGCACTCGTTTAATAAGAGTGCTAAAAAAT
AAAAAATGGAGGAAAATATA

Downstream 100 bases:

>100_bases
AATTATAAAAGCAATCATTTTTTTGGTTGTCTTTTGTCTATCTTAAAATCTATAAAATTAAAAATATATTCTTAAAAAGG
AGCTAAAATGTCAAAAGATA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVVAVGEGKTNHHGTLISPLVKVGDTVIFEKFAGTTVKMDGEE
FLILKDSDLLAIVE

Sequences:

>Translated_94_residues
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVVAVGEGKTNHHGTLISPLVKVGDTVIFEKFAGTTVKMDGEE
FLILKDSDLLAIVE
>Mature_94_residues
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVVAVGEGKTNHHGTLISPLVKVGDTVIFEKFAGTTVKMDGEE
FLILKDSDLLAIVE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=49.4736842105263, Blast_Score=79, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=39.5604395604396, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=38.2022471910112, Blast_Score=66, Evalue=8e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_LACLA (P37283)

Other databases:

- EMBL:   X71132
- EMBL:   AE005176
- PIR:   JN0660
- PIR:   S32105
- RefSeq:   NP_266549.1
- ProteinModelPortal:   P37283
- SMR:   P37283
- GeneID:   1114004
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L198515
- NMPDR:   fig|272623.1.peg.401
- HOGENOM:   HBG703377
- OMA:   KPMQGEV
- ProtClustDB:   PRK00364
- BioCyc:   LLAC272623:L198515-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10221; Mature: 10221

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVVAVGEGKTNHHGTLISPLVKV
CCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHC
GDTVIFEKFAGTTVKMDGEEFLILKDSDLLAIVE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVVAVGEGKTNHHGTLISPLVKV
CCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHC
GDTVIFEKFAGTTVKMDGEEFLILKDSDLLAIVE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486277; 11337471