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The map label for this gene is ycdH

Identifier: 15672220

GI number: 15672220

Start: 235128

End: 236588

Strand: Reverse

Name: ycdH

Synonym: L35134

Alternate gene names: 15672220

Gene position: 236588-235128 (Counterclockwise)

Preceding gene: 30023983

Following gene: 15672218

Centisome position: 10.0

GC content: 39.01

Gene sequence:

>1461_bases
TTGAATAAAATACAAGAAAAACGTTCCATAAGAGCCTTTATGCTCTCCAATGTGATGGCAGGTTTAGAAGGGTCAATCGT
AGCGACCGCTCTACCTGCAATGATGGCGGAATTACATGGAATTAAATTAATGAGTTGGGTTGTAACCATTTATATGCTCC
TCATGGCGGTTTCTTCTCCCATTTGGACGAAATTAGCCGAACGCTTTGAATATAAACAAATGTTTGTGCTTGGCACACTC
TTATTTACAATAGGTTCTCTCGGCGAAGGATTAGCCATTAATATGCTAATGGTTATTGTCGCACGCGCGCTCATGGGACT
TGGTGCTGGTGTGATGATTCAACTTCCTTTTGTCATCTATGGAATGATGTATCAAGCCGATGAGCGAAGACGAGTGATTG
GAAATACTGTCGCTGCTTATTCATTTTCAACTATTGCAGGACCAATTGTCGGGGGGCTGATTGTCACTTTACTTGACTGG
CGTTGGGTCTTTTTCATCAATATTCCAATTGGGATTTATATGGCTTTTATTGTTTGGAAAAATTTCGACTTGAAAACAGA
CCATACTAAAAAATCAATTGATTTTGCTGGCTCTGCTTCTTTATCCATCGCTGTCATTGCAATAATGTTGCATTTCCAAA
TGATGGGAAATGCAGTCATTAATCTTCCTCTCCTCCTTATCTTATTAGTTGTAAGTTTTCTCTTTTTCATCGGATTTTAT
TTTGCTGAAAAACGGGCAGTTGACCCAATCGTTCCACTTGAACTTTTCAAAAACCCTTCATTTATCGCTAAAAATATCAT
GTTTTTCATGCAATATGGCTTCTTTGGTTTTTACACAAATTATCTGCCTACTTGGGGACAAGGAGTCATGGGCGCAACGG
CTTTAGTCGGCGGAATGGTTTTGATTCCATCAGCAATCATGCTGGTTATAGGCACTAGAAATGTCAATCATCTCATTCAA
AAAGTGGGAGAAAAGAAAACAATCTATATTGGATTTTCCATTATGGTTTTAGGGGCAATTTTCTTATTTAGCTTGCCTGA
ACATGCCTCAATTATGATGCTCTTTGTGGCAACAGCAATTCTTGGAACTGCCTTTGGAATTGTCAATATCACCTTGCAAG
TTGCGGTTCAAGAAAGTGTTGCTAAGCATTTGATTGGTGCAGCGACCGCGGTTAATGCACTACTAAGAACAATGGGAACA
ACGCTTGTTTTATCTGGGCTATCCATTGCCCTTAATCGTACATTTACTGAGGCAACAGCACATAATCCAAAACTTACAAC
AACACTTCTTAATCAAATTTCTGATGCAAAAGCTTTAAAAAATATTCCAGTAAATCTTATTGCCCCTTTGCGTCACACCT
TATTTAACGGCATGCACTTGCTTGCTCTTATCTCAGGATTACTTCTTTTCATCGCTCTTTTTGTCAATTGGCTCGACCCT
TGGAAAAAAGGCTTAGAATAG

Upstream 100 bases:

>100_bases
TGACTTAGAGTAACTCTAACTTGCTATAATATAGCATGTTGATTTCAAAGTGTCAACCACCGCATTTTGAATCTTATTTT
AAAATAGAAAAGAGTAAAAA

Downstream 100 bases:

>100_bases
GAAAAAAACTGCTGACAGGCTCGTCAGTAGTTTTTATTTTGCTGACAAAACTTCTGTCATAGGATAGCCGTTTGCGCTTT
AGCGCATTTACGGATATGCT

Product: transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNKIQEKRSIRAFMLSNVMAGLEGSIVATALPAMMAELHGIKLMSWVVTIYMLLMAVSSPIWTKLAERFEYKQMFVLGTL
LFTIGSLGEGLAINMLMVIVARALMGLGAGVMIQLPFVIYGMMYQADERRRVIGNTVAAYSFSTIAGPIVGGLIVTLLDW
RWVFFINIPIGIYMAFIVWKNFDLKTDHTKKSIDFAGSASLSIAVIAIMLHFQMMGNAVINLPLLLILLVVSFLFFIGFY
FAEKRAVDPIVPLELFKNPSFIAKNIMFFMQYGFFGFYTNYLPTWGQGVMGATALVGGMVLIPSAIMLVIGTRNVNHLIQ
KVGEKKTIYIGFSIMVLGAIFLFSLPEHASIMMLFVATAILGTAFGIVNITLQVAVQESVAKHLIGAATAVNALLRTMGT
TLVLSGLSIALNRTFTEATAHNPKLTTTLLNQISDAKALKNIPVNLIAPLRHTLFNGMHLLALISGLLLFIALFVNWLDP
WKKGLE

Sequences:

>Translated_486_residues
MNKIQEKRSIRAFMLSNVMAGLEGSIVATALPAMMAELHGIKLMSWVVTIYMLLMAVSSPIWTKLAERFEYKQMFVLGTL
LFTIGSLGEGLAINMLMVIVARALMGLGAGVMIQLPFVIYGMMYQADERRRVIGNTVAAYSFSTIAGPIVGGLIVTLLDW
RWVFFINIPIGIYMAFIVWKNFDLKTDHTKKSIDFAGSASLSIAVIAIMLHFQMMGNAVINLPLLLILLVVSFLFFIGFY
FAEKRAVDPIVPLELFKNPSFIAKNIMFFMQYGFFGFYTNYLPTWGQGVMGATALVGGMVLIPSAIMLVIGTRNVNHLIQ
KVGEKKTIYIGFSIMVLGAIFLFSLPEHASIMMLFVATAILGTAFGIVNITLQVAVQESVAKHLIGAATAVNALLRTMGT
TLVLSGLSIALNRTFTEATAHNPKLTTTLLNQISDAKALKNIPVNLIAPLRHTLFNGMHLLALISGLLLFIALFVNWLDP
WKKGLE
>Mature_486_residues
MNKIQEKRSIRAFMLSNVMAGLEGSIVATALPAMMAELHGIKLMSWVVTIYMLLMAVSSPIWTKLAERFEYKQMFVLGTL
LFTIGSLGEGLAINMLMVIVARALMGLGAGVMIQLPFVIYGMMYQADERRRVIGNTVAAYSFSTIAGPIVGGLIVTLLDW
RWVFFINIPIGIYMAFIVWKNFDLKTDHTKKSIDFAGSASLSIAVIAIMLHFQMMGNAVINLPLLLILLVVSFLFFIGFY
FAEKRAVDPIVPLELFKNPSFIAKNIMFFMQYGFFGFYTNYLPTWGQGVMGATALVGGMVLIPSAIMLVIGTRNVNHLIQ
KVGEKKTIYIGFSIMVLGAIFLFSLPEHASIMMLFVATAILGTAFGIVNITLQVAVQESVAKHLIGAATAVNALLRTMGT
TLVLSGLSIALNRTFTEATAHNPKLTTTLLNQISDAKALKNIPVNLIAPLRHTLFNGMHLLALISGLLLFIALFVNWLDP
WKKGLE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=351, Percent_Identity=27.6353276353276, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87081983, Length=414, Percent_Identity=22.7053140096618, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789042, Length=438, Percent_Identity=24.6575342465753, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788710, Length=320, Percent_Identity=26.875, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788392, Length=357, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=459, Percent_Identity=26.1437908496732, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321663, Length=146, Percent_Identity=29.4520547945205, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6325455, Length=153, Percent_Identity=32.6797385620915, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323735, Length=312, Percent_Identity=23.3974358974359, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319783, Length=389, Percent_Identity=25.706940874036, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319770, Length=383, Percent_Identity=25.5874673629243, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53434; Mature: 53434

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCC
>Mature Secondary Structure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HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]