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The map label for this gene is pdxS

Identifier: 15668858

GI number: 15668858

Start: 603197

End: 604189

Strand: Reverse

Name: pdxS

Synonym: MJ0677

Alternate gene names: 15668858

Gene position: 604189-603197 (Counterclockwise)

Preceding gene: 15668859

Following gene: 15668857

Centisome position: 36.29

GC content: 39.48

Gene sequence:

>993_bases
ATGAAAAAAGGAACTGACTTATTAAAGAAAGGATTTGCCAAGATGGTTAAGCATGGGGTTGTAATGGATGTTACCAACGT
AGAACAAGCACAAATAGCCGAAGAGGCTGGAGCTGTTGCAGTTATGGCTTTGGAGAGAGTTCCTGCGGATATTAGGGCAG
CTGGTGGAGTTGCAAGAATGTCAGACCCAGCTTTAATTGAAGAGATAATGGATGCTGTCTCAATTCCAGTTATGGCTAAG
TGTAGAATTGGACATACAACAGAGGCTTTAGTTTTAGAGGCTATTGGAGTAGATATGATTGATGAAAGTGAAGTTTTAAC
CCAAGCAGACCCATTCTTCCACATATACAAGAAGAAGTTTAACGTCCCATTTGTCTGTGGAGCAAGAAACTTAGGAGAGG
CAGTTAGAAGAATCTGGGAAGGAGCGGCAATGATAAGAACTAAGGGAGAGGCAGGGACTGGAAATATAGTTGAGGCAGTT
AGACACATGAGATTGATGAATGAAGCTATAGCTCAATTGCAGAGAATGACAGATGAAGAAGTTTATGGAGTTGCTAAATT
CTATGCTAACAGATATGCAGAATTAGCTAAGACAGTTAGAGAGGGAATGGGGTTGCCAGCAACTGTTTTAGAAAATGAGC
CAATCTATGAGGGCTTTACACTGGCTGAGATTATTGATGGGTTGTATGAGGTTTTATTAGAAGTTAAAAAATTAGGAAGA
TTGCCAGTAGTTAATTTTGCAGCTGGTGGGGTTGCAACACCGGCAGATGCTGCTTTAATGATGCAGCTTGGTTCTGATGG
AGTATTTGTTGGTTCAGGAATATTTAAATCAGAAAATCCATTGGAGAGAGCAAGGGCAATTGTTGAAGCTACTTATAACT
ATGATAAGCCTGATATTGTTGCTGAAGTTAGTAAGAATTTAGGAGAAGCTATGAAAGGAATAGATATAACTCAAATAAGC
GAAGCTGAGAAAATGCAATATAGAGGAGATTAA

Upstream 100 bases:

>100_bases
AGCAATATTTGTGCTAATAATTTATCACTAAATTAAACATATATAGTTGGAGACTATAATTTCATAACAAACTTTTATCA
ATGATTATGGAGGGAGAGTT

Downstream 100 bases:

>100_bases
ATTTGAATTTTACTTCATTTTTTTAATTTTGTTTTAAAATTTTATTGAAAGATTGTAAAAAATATATCAAAATATTTAAG
TATTCAATAAAAGTTAAAGA

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKKGTDLLKKGFAKMVKHGVVMDVTNVEQAQIAEEAGAVAVMALERVPADIRAAGGVARMSDPALIEEIMDAVSIPVMAK
CRIGHTTEALVLEAIGVDMIDESEVLTQADPFFHIYKKKFNVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGTGNIVEAV
RHMRLMNEAIAQLQRMTDEEVYGVAKFYANRYAELAKTVREGMGLPATVLENEPIYEGFTLAEIIDGLYEVLLEVKKLGR
LPVVNFAAGGVATPADAALMMQLGSDGVFVGSGIFKSENPLERARAIVEATYNYDKPDIVAEVSKNLGEAMKGIDITQIS
EAEKMQYRGD

Sequences:

>Translated_330_residues
MKKGTDLLKKGFAKMVKHGVVMDVTNVEQAQIAEEAGAVAVMALERVPADIRAAGGVARMSDPALIEEIMDAVSIPVMAK
CRIGHTTEALVLEAIGVDMIDESEVLTQADPFFHIYKKKFNVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGTGNIVEAV
RHMRLMNEAIAQLQRMTDEEVYGVAKFYANRYAELAKTVREGMGLPATVLENEPIYEGFTLAEIIDGLYEVLLEVKKLGR
LPVVNFAAGGVATPADAALMMQLGSDGVFVGSGIFKSENPLERARAIVEATYNYDKPDIVAEVSKNLGEAMKGIDITQIS
EAEKMQYRGD
>Mature_330_residues
MKKGTDLLKKGFAKMVKHGVVMDVTNVEQAQIAEEAGAVAVMALERVPADIRAAGGVARMSDPALIEEIMDAVSIPVMAK
CRIGHTTEALVLEAIGVDMIDESEVLTQADPFFHIYKKKFNVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGTGNIVEAV
RHMRLMNEAIAQLQRMTDEEVYGVAKFYANRYAELAKTVREGMGLPATVLENEPIYEGFTLAEIIDGLYEVLLEVKKLGR
LPVVNFAAGGVATPADAALMMQLGSDGVFVGSGIFKSENPLERARAIVEATYNYDKPDIVAEVSKNLGEAMKGIDITQIS
EAEKMQYRGD

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=315, Percent_Identity=55.5555555555556, Blast_Score=327, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6321049, Length=315, Percent_Identity=55.5555555555556, Blast_Score=311, Evalue=7e-86,
Organism=Saccharomyces cerevisiae, GI6323996, Length=315, Percent_Identity=55.2380952380952, Blast_Score=311, Evalue=9e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_METJA (Q58090)

Other databases:

- EMBL:   L77117
- PIR:   E64384
- RefSeq:   NP_247661.1
- PDB:   2YZR
- PDBsum:   2YZR
- ProteinModelPortal:   Q58090
- SMR:   Q58090
- GeneID:   1451543
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0677
- NMPDR:   fig|243232.1.peg.698
- TIGR:   MJ0677
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- ProtClustDB:   PRK04180
- BioCyc:   MJAN243232:MJ_0677-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- InterPro:   IPR008867
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; PF05690 ThiG; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 35857; Mature: 35857

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGTDLLKKGFAKMVKHGVVMDVTNVEQAQIAEEAGAVAVMALERVPADIRAAGGVARM
CCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCHHHHHHHHCCHHHHHCCCCCCC
SDPALIEEIMDAVSIPVMAKCRIGHTTEALVLEAIGVDMIDESEVLTQADPFFHIYKKKF
CCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHC
NVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGTGNIVEAVRHMRLMNEAIAQLQRMTDEE
CCCEEECCHHHHHHHHHHHCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
VYGVAKFYANRYAELAKTVREGMGLPATVLENEPIYEGFTLAEIIDGLYEVLLEVKKLGR
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LPVVNFAAGGVATPADAALMMQLGSDGVFVGSGIFKSENPLERARAIVEATYNYDKPDIV
CCEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHH
AEVSKNLGEAMKGIDITQISEAEKMQYRGD
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKGTDLLKKGFAKMVKHGVVMDVTNVEQAQIAEEAGAVAVMALERVPADIRAAGGVARM
CCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCHHHHHHHHCCHHHHHCCCCCCC
SDPALIEEIMDAVSIPVMAKCRIGHTTEALVLEAIGVDMIDESEVLTQADPFFHIYKKKF
CCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHC
NVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGTGNIVEAVRHMRLMNEAIAQLQRMTDEE
CCCEEECCHHHHHHHHHHHCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
VYGVAKFYANRYAELAKTVREGMGLPATVLENEPIYEGFTLAEIIDGLYEVLLEVKKLGR
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LPVVNFAAGGVATPADAALMMQLGSDGVFVGSGIFKSENPLERARAIVEATYNYDKPDIV
CCEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHH
AEVSKNLGEAMKGIDITQISEAEKMQYRGD
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087