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The map label for this gene is hypE [C]

Identifier: 15668857

GI number: 15668857

Start: 602081

End: 603088

Strand: Reverse

Name: hypE [C]

Synonym: MJ0676

Alternate gene names: 15668857

Gene position: 603088-602081 (Counterclockwise)

Preceding gene: 15668858

Following gene: 15668856

Centisome position: 36.22

GC content: 35.42

Gene sequence:

>1008_bases
ATGAAAATCACACGAATGCATGGAGCTGGAGGAAAGGTAATGCAGGAGCTTATAAAAGATGTAATATTGAAAAATTTGGA
GATAACATCAGTTAATGGAGGAATTGGCTTAGAAAGCTTGGATGATTCAGCAACTATCCCAATAGGTGATAAGGAGATTG
TTTTTACTGTTGATGGACACACAGTTAAACCAATATTCTTCCCAGGTGGAGATATTGGAAGATTGGCTGTTAGTGGAACT
GTAAATGATTTAGCAGTTATGGGAGCTAAGCCATTAGCTCTATCTCTATCTTTAATAATTCCAGAAGGTTTTAACTTAGA
AGATTTGGAGAAAATAGTTAAATCAATAAACGAAACTTCTAAAGAGGCTGAAGTAGCAATAATAACAGGAGATACAAAGG
TATCTGATGGAGTTGATGATATCATAATCTCAACTGCTGGAATAGGGATTGTTGATAGGGGAAAGGCAATAAGGGATTGT
AATGTTCAAGAGGGAGATGCAATAATTGTTTCTGGAAATATAGGAGAGCATGGATTAGCTATTTTATTATCAAGGGAGGG
ATTTGATTTTGAAACAAACATAAAATCAGATGTAGCTCCAATAAATAAATTAATTGAGAGGGTTTTAGAAGAGGGCATTC
AAATAAATGCCATGAAAGACCCTACAAGAGGAGGTTTGGCAGATGCGTTAAATGAGATGGCTGAAAAGAGTAATATTGGC
ATAACTATATTTGAGGATAAAATCCCAATAAGTGATGAAGTTCAATCAATTTGTGATATTCTTGGCTTAGACCCTTTAAC
TATAGCAAATGAAGGAAAGGTAGTTATGGCAGTTAAAAAGGAAGATGCTGAAAGATGCTTAGAGATTTTAAGGGAGCATC
CATTAGGAAAGAATGCTGAAATCATTGGCTATGCTACAAAAGAACATAAGGGAGTTATAATAGAGACGATTGTTGGTAGA
AGGATAGTGGATATGCCTATTGGCGATCCGATACCAAGAGTTTGTTAA

Upstream 100 bases:

>100_bases
TTTACTTCATTTTTTTAATTTTGTTTTAAAATTTTATTGAAAGATTGTAAAAAATATATCAAAATATTTAAGTATTCAAT
AAAAGTTAAAGAGTGAGATT

Downstream 100 bases:

>100_bases
TATTCATAATGCAATTTTTAAAAGTTTTGATGAAACTTTTCTAAAAGTTTCATGCGAGACATATTGTTGGTAGGAGAATT
GTCGATATGCCGATTGGAGA

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGHTVKPIFFPGGDIGRLAVSGT
VNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETSKEAEVAIITGDTKVSDGVDDIIISTAGIGIVDRGKAIRDC
NVQEGDAIIVSGNIGEHGLAILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNIG
ITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNAEIIGYATKEHKGVIIETIVGR
RIVDMPIGDPIPRVC

Sequences:

>Translated_335_residues
MKITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGHTVKPIFFPGGDIGRLAVSGT
VNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETSKEAEVAIITGDTKVSDGVDDIIISTAGIGIVDRGKAIRDC
NVQEGDAIIVSGNIGEHGLAILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNIG
ITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNAEIIGYATKEHKGVIIETIVGR
RIVDMPIGDPIPRVC
>Mature_335_residues
MKITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGHTVKPIFFPGGDIGRLAVSGT
VNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETSKEAEVAIITGDTKVSDGVDDIIISTAGIGIVDRGKAIRDC
NVQEGDAIIVSGNIGEHGLAILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNIG
ITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNAEIIGYATKEHKGVIIETIVGR
RIVDMPIGDPIPRVC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=38.5756676557863, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y676_METJA (Q58089)

Other databases:

- EMBL:   L77117
- PIR:   D64384
- RefSeq:   NP_247660.1
- ProteinModelPortal:   Q58089
- SMR:   Q58089
- GeneID:   1451542
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0676
- NMPDR:   fig|243232.1.peg.697
- TIGR:   MJ0676
- HOGENOM:   HBG287946
- OMA:   AMRDPTR
- ProtClustDB:   CLSK876288
- BioCyc:   MJAN243232:MJ_0676-MONOMER
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188
- PIRSF:   PIRSF005644
- TIGRFAMs:   TIGR02124

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: NA

Molecular weight: Translated: 35814; Mature: 35814

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGH
CEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCC
TVKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETS
EEEEEEECCCCCCEEEEECCCHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCC
KEAEVAIITGDTKVSDGVDDIIISTAGIGIVDRGKAIRDCNVQEGDAIIVSGNIGEHGLA
CCCEEEEEECCCCCCCCCHHEEEEECCCCEEECCCEEECCCCCCCCEEEEECCCCCCCEE
ILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNIG
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCC
ITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNAE
EEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCE
IIGYATKEHKGVIIETIVGRRIVDMPIGDPIPRVC
EEEEECCCCCCEEEEEHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGH
CEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCC
TVKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETS
EEEEEEECCCCCCEEEEECCCHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCC
KEAEVAIITGDTKVSDGVDDIIISTAGIGIVDRGKAIRDCNVQEGDAIIVSGNIGEHGLA
CCCEEEEEECCCCCCCCCHHEEEEECCCCEEECCCEEECCCCCCCCEEEEECCCCCCCEE
ILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNIG
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCC
ITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNAE
EEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCE
IIGYATKEHKGVIIETIVGRRIVDMPIGDPIPRVC
EEEEECCCCCCEEEEEHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087