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The map label for this gene is 15668715

Identifier: 15668715

GI number: 15668715

Start: 470326

End: 471357

Strand: Reverse

Name: 15668715

Synonym: MJ0535

Alternate gene names: NA

Gene position: 471357-470326 (Counterclockwise)

Preceding gene: 15668716

Following gene: 15668713

Centisome position: 28.31

GC content: 31.69

Gene sequence:

>1032_bases
TTGGTGTCCATTATGCCAAAAATTTTATACAATCCAGAGGTTTTAGGGCATAAACCAAAATCCTACCATGTTGAAAATCC
AGAGAGAGTTTTAACCATTTTAAACAGCTTAAAATCTAATGGCTTTGATGATATAGTTTTAATTGAAGGAAAATCTACAA
TTAATGAGATTTTAGAGATTCATAGTAGAGATTATGTATATTCAATTATAAATCTAAGCAAATCATTTAACTATTATGAT
GGTGATACATATCTCTGTGATAGAACCTTAGACGCAGCATTAACTGCCTTTAAATTGGCAAAAGAAGCTGTAAAATTAGC
ATTAAAAGATAGGGATTTATACTTTGCATTAACAAGACCTCCAGGACATCATGCTGGAATTTCTGGAAGGGCTTTAGGAG
CAATGTCAAACGGTTTTTGCATATTTAATAATATAGCAGGAGCTGCAAGATTAGCTAAAAATTATATGAAAAAAGTCATA
ATAATTGATTTTGATGTGCATCATGGAAACGGCACTCAAGAAATCTTCTGGAATGATAATAGAGTTATTCATATAGATTT
CCACCAAAGAGGCATCTATCCAGGAACTGGAGATATATTAGATATTGGAGGAGAAGAGGCAAAAGGGACTAAAATAAATC
TTCCTTTCCCAGCACATTCAACTGATGCTGATTATATATTTGCATGGAATGAGATTGTTGAGCCAATTTTAAATTACTTT
AGTCCAGATACTGTTTTAGTTTCTGCAGGTTTTGATGCATTTATAAATGATGGCCTTGCAAGTATGGACTTAACTGAAAC
ATTTTATAGATTTGTAGGAGCTAAGCTAAGCGGATATAGTGTTACAGCAGTTTTAGAAGGAGGATACAGTATAGGTTTAA
AGTATGCTCCACCAGCATTTTTAGATGGATATGTTGATGCTAAAGATGTGTTGGATAATTTAGAGGATTATACAGTTATT
AATTCTAATGAAGTTAAATCAATGGTTAAAAATGTTAAAAAGATAATTGGGGAGTATTTGGATATTTTTTAA

Upstream 100 bases:

>100_bases
AGAACAATATTGTATCAAAAACTCTTTTTTATCCACTCTAAAATATCCTAAATAATTTTTTATATCCCAAAAGAGAAATA
TTAAACTAAAAACCTATTTT

Downstream 100 bases:

>100_bases
TAGGACTCCGCAGTTTATATATTATAATAAGTAGTTAGACGTTAATTTTTGCTAACTTTCTACCAAACTCTTTAATTTTT
TTAATATCATTTTCTTTTGG

Product: acetylpolyamine aminohydrolase AphA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MVSIMPKILYNPEVLGHKPKSYHVENPERVLTILNSLKSNGFDDIVLIEGKSTINEILEIHSRDYVYSIINLSKSFNYYD
GDTYLCDRTLDAALTAFKLAKEAVKLALKDRDLYFALTRPPGHHAGISGRALGAMSNGFCIFNNIAGAARLAKNYMKKVI
IIDFDVHHGNGTQEIFWNDNRVIHIDFHQRGIYPGTGDILDIGGEEAKGTKINLPFPAHSTDADYIFAWNEIVEPILNYF
SPDTVLVSAGFDAFINDGLASMDLTETFYRFVGAKLSGYSVTAVLEGGYSIGLKYAPPAFLDGYVDAKDVLDNLEDYTVI
NSNEVKSMVKNVKKIIGEYLDIF

Sequences:

>Translated_343_residues
MVSIMPKILYNPEVLGHKPKSYHVENPERVLTILNSLKSNGFDDIVLIEGKSTINEILEIHSRDYVYSIINLSKSFNYYD
GDTYLCDRTLDAALTAFKLAKEAVKLALKDRDLYFALTRPPGHHAGISGRALGAMSNGFCIFNNIAGAARLAKNYMKKVI
IIDFDVHHGNGTQEIFWNDNRVIHIDFHQRGIYPGTGDILDIGGEEAKGTKINLPFPAHSTDADYIFAWNEIVEPILNYF
SPDTVLVSAGFDAFINDGLASMDLTETFYRFVGAKLSGYSVTAVLEGGYSIGLKYAPPAFLDGYVDAKDVLDNLEDYTVI
NSNEVKSMVKNVKKIIGEYLDIF
>Mature_343_residues
MVSIMPKILYNPEVLGHKPKSYHVENPERVLTILNSLKSNGFDDIVLIEGKSTINEILEIHSRDYVYSIINLSKSFNYYD
GDTYLCDRTLDAALTAFKLAKEAVKLALKDRDLYFALTRPPGHHAGISGRALGAMSNGFCIFNNIAGAARLAKNYMKKVI
IIDFDVHHGNGTQEIFWNDNRVIHIDFHQRGIYPGTGDILDIGGEEAKGTKINLPFPAHSTDADYIFAWNEIVEPILNYF
SPDTVLVSAGFDAFINDGLASMDLTETFYRFVGAKLSGYSVTAVLEGGYSIGLKYAPPAFLDGYVDAKDVLDNLEDYTVI
NSNEVKSMVKNVKKIIGEYLDIF

Specific function: Putative deacetylase

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family

Homologues:

Organism=Homo sapiens, GI13128864, Length=309, Percent_Identity=32.3624595469256, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI20070354, Length=294, Percent_Identity=32.312925170068, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI148539870, Length=314, Percent_Identity=30.5732484076433, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI169234807, Length=314, Percent_Identity=30.5732484076433, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI153085395, Length=193, Percent_Identity=35.7512953367876, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI62750349, Length=208, Percent_Identity=36.5384615384615, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI62750347, Length=208, Percent_Identity=36.5384615384615, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI30795202, Length=288, Percent_Identity=30.9027777777778, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI30795204, Length=288, Percent_Identity=30.9027777777778, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI17158039, Length=288, Percent_Identity=31.25, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI226529806, Length=291, Percent_Identity=28.1786941580756, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI13128860, Length=264, Percent_Identity=28.4090909090909, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI293336691, Length=264, Percent_Identity=28.4090909090909, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI13128862, Length=280, Percent_Identity=25.3571428571429, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI262073088, Length=133, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI8923769, Length=133, Percent_Identity=27.0676691729323, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17540334, Length=305, Percent_Identity=33.7704918032787, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI193206283, Length=305, Percent_Identity=33.7704918032787, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17540332, Length=305, Percent_Identity=33.7704918032787, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI193209491, Length=309, Percent_Identity=31.7152103559871, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17537347, Length=342, Percent_Identity=31.2865497076023, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25154020, Length=312, Percent_Identity=30.4487179487179, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25154022, Length=312, Percent_Identity=30.1282051282051, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17508561, Length=263, Percent_Identity=28.1368821292776, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561978, Length=222, Percent_Identity=31.0810810810811, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534739, Length=149, Percent_Identity=36.241610738255, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324307, Length=361, Percent_Identity=29.3628808864266, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6321244, Length=287, Percent_Identity=28.2229965156794, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=144, Percent_Identity=31.9444444444444, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=148, Percent_Identity=28.3783783783784, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281360899, Length=290, Percent_Identity=33.448275862069, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24642146, Length=296, Percent_Identity=33.445945945946, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24642144, Length=296, Percent_Identity=33.445945945946, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24642142, Length=296, Percent_Identity=33.445945945946, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24641720, Length=205, Percent_Identity=35.1219512195122, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281360801, Length=205, Percent_Identity=35.1219512195122, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281360799, Length=205, Percent_Identity=35.1219512195122, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24657891, Length=265, Percent_Identity=27.9245283018868, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24644244, Length=133, Percent_Identity=35.3383458646617, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y535_METJA (Q57955)

Other databases:

- EMBL:   L77117
- PIR:   G64366
- RefSeq:   NP_247514.1
- ProteinModelPortal:   Q57955
- SMR:   Q57955
- GeneID:   1451400
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0535
- NMPDR:   fig|243232.1.peg.551
- TIGR:   MJ0535
- HOGENOM:   HBG713516
- OMA:   HIRSLSK
- ProtClustDB:   CLSK2749890
- BioCyc:   MJAN243232:MJ_0535-MONOMER
- InterPro:   IPR000286
- Gene3D:   G3DSA:3.40.800.20
- PANTHER:   PTHR10625
- PRINTS:   PR01270

Pfam domain/function: PF00850 Hist_deacetyl

EC number: NA

Molecular weight: Translated: 38175; Mature: 38175

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIMPKILYNPEVLGHKPKSYHVENPERVLTILNSLKSNGFDDIVLIEGKSTINEILEI
CCCCCCHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHH
HSRDYVYSIINLSKSFNYYDGDTYLCDRTLDAALTAFKLAKEAVKLALKDRDLYFALTRP
HCCCCEEEEEHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHEECCCEEEEEECC
PGHHAGISGRALGAMSNGFCIFNNIAGAARLAKNYMKKVIIIDFDVHHGNGTQEIFWNDN
CCCCCCCCCCEECCCCCCEEEEECCHHHHHHHHHHHCEEEEEEEEEECCCCCCEEEECCC
RVIHIDFHQRGIYPGTGDILDIGGEEAKGTKINLPFPAHSTDADYIFAWNEIVEPILNYF
EEEEEEECCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHC
SPDTVLVSAGFDAFINDGLASMDLTETFYRFVGAKLSGYSVTAVLEGGYSIGLKYAPPAF
CCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEECCHHH
LDGYVDAKDVLDNLEDYTVINSNEVKSMVKNVKKIIGEYLDIF
HCCCCCHHHHHCCCHHEEEECCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSIMPKILYNPEVLGHKPKSYHVENPERVLTILNSLKSNGFDDIVLIEGKSTINEILEI
CCCCCCHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHH
HSRDYVYSIINLSKSFNYYDGDTYLCDRTLDAALTAFKLAKEAVKLALKDRDLYFALTRP
HCCCCEEEEEHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHEECCCEEEEEECC
PGHHAGISGRALGAMSNGFCIFNNIAGAARLAKNYMKKVIIIDFDVHHGNGTQEIFWNDN
CCCCCCCCCCEECCCCCCEEEEECCHHHHHHHHHHHCEEEEEEEEEECCCCCCEEEECCC
RVIHIDFHQRGIYPGTGDILDIGGEEAKGTKINLPFPAHSTDADYIFAWNEIVEPILNYF
EEEEEEECCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHC
SPDTVLVSAGFDAFINDGLASMDLTETFYRFVGAKLSGYSVTAVLEGGYSIGLKYAPPAF
CCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEECCHHH
LDGYVDAKDVLDNLEDYTVINSNEVKSMVKNVKKIIGEYLDIF
HCCCCCHHHHHCCCHHEEEECCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087