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The map label for this gene is nrdB [H]

Identifier: 15602584

GI number: 15602584

Start: 847690

End: 848820

Strand: Direct

Name: nrdB [H]

Synonym: PM0719

Alternate gene names: 15602584

Gene position: 847690-848820 (Clockwise)

Preceding gene: 15602583

Following gene: 15602585

Centisome position: 37.55

GC content: 38.82

Gene sequence:

>1131_bases
ATGGCCTATACTACCTTTTCGCAAAACAAAAACGATCAATTAAAAGAGCCAATGTTCTTTGGTCAAAATGTTAACGTTGC
TCGTTATGACCAACAAAAATATGAAACTTTTGAGAAATTGATTGAAAAACAACTTTCGTTCTTCTGGCGTCCTGAAGAAG
TCGATGTGTCACAAGACCGTATCGATTACCAAGCGTTACCAGAACACGAAAAACATATTTTTATCAGTAACTTAAAATAC
CAAACCTTATTAGATTCCATTCAAGGTCGCAGTCCAAACGTGGCGCTCTTACCACTTGTGTCTATCCCTGAATTAGAAAC
TTGGATCGAAACTTGGACTTTCTCTGAAACCATTCACTCGCGTTCTTATACCCATATTATCCGTAACATTGTGAACGATC
CTTCCGTGATTTTTGATGATATCGTGACCAATGAAGAAATTATCAAACGCGCCAAAGATATTTCTGCTTATTATGATGAT
TTAATTCGTGACTCACAGCTTTATACTTTATATGGTGAAGGCACTTACAATGTTGATGGTCAAGATTGTGTGGTCACATT
ACGTAATTTGAAAAGACAACTTTACTTATGCTTAATGAGTGTCAATGCGCTAGAAGCGATCCGTTTCTACGTGTCTTTTG
CTTGTTCTTTCGCCTTTGCTGAACGCAAATTGATGGAAGGGAATGCAAAAATCATTAAATTTATCGCACGTGATGAAGCT
TTACACTTAACCGGTACACAACATATCCTCAACATTATGGCATCCGGTCAAGATGATCCAGAAATGGCAGAGATCGTGGA
AGAATGTAAACAAGAAGCTTACGATTTGTTTGTTGCTGCGGCAGAGCAAGAAAAAGAATGGGCTGATTATTTGTTCAAAG
ATGGCTCAATGATTGGCTTGAACCGCGATATTTTAGTGCAATATGTGGAATATATTACCAATATCCGGATGCAAGCAGTC
GGTCTCCCACTGCCTTTCCAGGCACGCTCTAATCCAATCCCTTGGATTAATGCTTGGTTAGTGTCGGATAATGTACAAGT
CGCCCCACAAGAAGTCGAAGTCAGCTCTTATTTAGTTGGTCAAATTGACTCAAAAGTCGATACCAAAGACTTTGGCGATT
TTGATCTCTAA

Upstream 100 bases:

>100_bases
TAAAATCGATGACTTAGGTAAAATGACAATGTTTTATTCATTTATTAAGCGTATCAAAAGTGCGGTGTTTTTCCCGTACT
TTTCCTATGGAGAGCACAAC

Downstream 100 bases:

>100_bases
ACGTTGTTAAAAAGGACCGCACTTTTCGCTTTTCTGAAAAGTGCGGTTATTTTTTCGCTAATATTTGCTAATGAAAATTC
ATTTAATCCATAGCCAAATG

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MAYTTFSQNKNDQLKEPMFFGQNVNVARYDQQKYETFEKLIEKQLSFFWRPEEVDVSQDRIDYQALPEHEKHIFISNLKY
QTLLDSIQGRSPNVALLPLVSIPELETWIETWTFSETIHSRSYTHIIRNIVNDPSVIFDDIVTNEEIIKRAKDISAYYDD
LIRDSQLYTLYGEGTYNVDGQDCVVTLRNLKRQLYLCLMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIKFIARDEA
LHLTGTQHILNIMASGQDDPEMAEIVEECKQEAYDLFVAAAEQEKEWADYLFKDGSMIGLNRDILVQYVEYITNIRMQAV
GLPLPFQARSNPIPWINAWLVSDNVQVAPQEVEVSSYLVGQIDSKVDTKDFGDFDL

Sequences:

>Translated_376_residues
MAYTTFSQNKNDQLKEPMFFGQNVNVARYDQQKYETFEKLIEKQLSFFWRPEEVDVSQDRIDYQALPEHEKHIFISNLKY
QTLLDSIQGRSPNVALLPLVSIPELETWIETWTFSETIHSRSYTHIIRNIVNDPSVIFDDIVTNEEIIKRAKDISAYYDD
LIRDSQLYTLYGEGTYNVDGQDCVVTLRNLKRQLYLCLMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIKFIARDEA
LHLTGTQHILNIMASGQDDPEMAEIVEECKQEAYDLFVAAAEQEKEWADYLFKDGSMIGLNRDILVQYVEYITNIRMQAV
GLPLPFQARSNPIPWINAWLVSDNVQVAPQEVEVSSYLVGQIDSKVDTKDFGDFDL
>Mature_375_residues
AYTTFSQNKNDQLKEPMFFGQNVNVARYDQQKYETFEKLIEKQLSFFWRPEEVDVSQDRIDYQALPEHEKHIFISNLKYQ
TLLDSIQGRSPNVALLPLVSIPELETWIETWTFSETIHSRSYTHIIRNIVNDPSVIFDDIVTNEEIIKRAKDISAYYDDL
IRDSQLYTLYGEGTYNVDGQDCVVTLRNLKRQLYLCLMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIKFIARDEAL
HLTGTQHILNIMASGQDDPEMAEIVEECKQEAYDLFVAAAEQEKEWADYLFKDGSMIGLNRDILVQYVEYITNIRMQAVG
LPLPFQARSNPIPWINAWLVSDNVQVAPQEVEVSSYLVGQIDSKVDTKDFGDFDL

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1788567, Length=376, Percent_Identity=84.3085106382979, Blast_Score=671, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 43494; Mature: 43362

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYTTFSQNKNDQLKEPMFFGQNVNVARYDQQKYETFEKLIEKQLSFFWRPEEVDVSQDR
CCEECCCCCCCCCHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLVSIPELETWIETWTFSETIHS
CCHHCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
RSYTHIIRNIVNDPSVIFDDIVTNEEIIKRAKDISAYYDDLIRDSQLYTLYGEGTYNVDG
HHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCC
QDCVVTLRNLKRQLYLCLMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIKFIARDEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCE
LHLTGTQHILNIMASGQDDPEMAEIVEECKQEAYDLFVAAAEQEKEWADYLFKDGSMIGL
EEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NRDILVQYVEYITNIRMQAVGLPLPFQARSNPIPWINAWLVSDNVQVAPQEVEVSSYLVG
CHHHHHHHHHHHHCCHHHEECCCCCCCCCCCCCCEEEEEEEECCCEECCHHHHHHHHHHH
QIDSKVDTKDFGDFDL
HHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AYTTFSQNKNDQLKEPMFFGQNVNVARYDQQKYETFEKLIEKQLSFFWRPEEVDVSQDR
CEECCCCCCCCCHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLVSIPELETWIETWTFSETIHS
CCHHCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
RSYTHIIRNIVNDPSVIFDDIVTNEEIIKRAKDISAYYDDLIRDSQLYTLYGEGTYNVDG
HHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCC
QDCVVTLRNLKRQLYLCLMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIKFIARDEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCE
LHLTGTQHILNIMASGQDDPEMAEIVEECKQEAYDLFVAAAEQEKEWADYLFKDGSMIGL
EEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NRDILVQYVEYITNIRMQAVGLPLPFQARSNPIPWINAWLVSDNVQVAPQEVEVSSYLVG
CHHHHHHHHHHHHCCHHHEECCCCCCCCCCCCCCEEEEEEEECCCEECCHHHHHHHHHHH
QIDSKVDTKDFGDFDL
HHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]