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The map label for this gene is accA

Identifier: 15602157

GI number: 15602157

Start: 332880

End: 333833

Strand: Reverse

Name: accA

Synonym: PM0292

Alternate gene names: 15602157

Gene position: 333833-332880 (Counterclockwise)

Preceding gene: 15602158

Following gene: 15602156

Centisome position: 14.79

GC content: 41.09

Gene sequence:

>954_bases
ATGGCCCAAGAATATTTAGATTTTGAATTACCTATCGCAGAACTGGAAGCGAAAATCGAATCTCTGCGTTCTGTCGCAAG
TCAAGACGATGAAATTAATCTTGATGATGAAATTGCACGTTTGCAAAAGAAAAGTGCCGAGTTAACCAAAAAAACCTTTG
CCAATTTAGACGCATGGCAAGTGTCAAAAATGGCACGTCATCCAAATCGTCCTTATACACTTGATTATATTGAACGTATT
TTTACTGAATTTGAAGAATTAGCCGGTGATCGCGCCTTTGCCGATGATAAAGCCATTGTAGGCGGTTTAGCCCGTTTAGA
CGGCAAACCGGTTATGGTCATCGGTCACCAAAAAGGACGCAGTGTCAAAGACAAAGTCAAACGTAACTTTGGTATGCCTG
CCCCTGAAGGTTACCGTAAAGCTTTACGTTTAATGCAAATGGCGGAGCGTTTTAATTTACCGATTATTACCTTTATTGAT
ACACCGGGAGCATACCCAGGTGTAGGTGCAGAAGAACGTGGTCAGTCCGAGGCCATCGCTCGTAATTTACGTGAAATGTC
TACTTTAAAAGTACCAGTGATTTGTACCGTTATCGGTGAAGGCGGTTCAGGTGGCGCGTTAGCCATTGGTGTAGGTGATA
AAGTCAATATGTTGCAATACAGTACTTATTCTGTGATTTCACCTGAAGGTTGTGCCTCTATTTTATGGAAAAGCGCAGAA
AAAGCATCTACAGCAGCGGAAGTCATGGGATTAACGGCCAATCGTCTGAAAGAATTAAACTTAATTGACAGTATCATTGA
AGAACCGTTAGGTGGTGCACATCGTGATTTTGACGCGATGGCACATAACTTAAAACAACGTTTATTAGACGATCTCAAAG
AACTGGAAATGCTTGATGAAGATAATCTACTTCATCGTCGTTATAATCGTTTAATGGACTACGGTTACTGTTAA

Upstream 100 bases:

>100_bases
TTGCTAAAAAAAAGCATACAATATTGCCTATGTTTGCACCTTAATAAAAATCTTGCTAAAGTGCGCTACAAATTGTGCTA
ATTTAAGAACAGGAAGAAAA

Downstream 100 bases:

>100_bases
AACTCAATTAGTGCGGTACACATACCGCACTTTTTTTTGGGAAAGGTTATTATGCGTCGTATTTCACTTTTCATCACTGC
TATTTTCTCCCTTAGTTATT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MAQEYLDFELPIAELEAKIESLRSVASQDDEINLDDEIARLQKKSAELTKKTFANLDAWQVSKMARHPNRPYTLDYIERI
FTEFEELAGDRAFADDKAIVGGLARLDGKPVMVIGHQKGRSVKDKVKRNFGMPAPEGYRKALRLMQMAERFNLPIITFID
TPGAYPGVGAEERGQSEAIARNLREMSTLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAE
KASTAAEVMGLTANRLKELNLIDSIIEEPLGGAHRDFDAMAHNLKQRLLDDLKELEMLDEDNLLHRRYNRLMDYGYC

Sequences:

>Translated_317_residues
MAQEYLDFELPIAELEAKIESLRSVASQDDEINLDDEIARLQKKSAELTKKTFANLDAWQVSKMARHPNRPYTLDYIERI
FTEFEELAGDRAFADDKAIVGGLARLDGKPVMVIGHQKGRSVKDKVKRNFGMPAPEGYRKALRLMQMAERFNLPIITFID
TPGAYPGVGAEERGQSEAIARNLREMSTLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAE
KASTAAEVMGLTANRLKELNLIDSIIEEPLGGAHRDFDAMAHNLKQRLLDDLKELEMLDEDNLLHRRYNRLMDYGYC
>Mature_316_residues
AQEYLDFELPIAELEAKIESLRSVASQDDEINLDDEIARLQKKSAELTKKTFANLDAWQVSKMARHPNRPYTLDYIERIF
TEFEELAGDRAFADDKAIVGGLARLDGKPVMVIGHQKGRSVKDKVKRNFGMPAPEGYRKALRLMQMAERFNLPIITFIDT
PGAYPGVGAEERGQSEAIARNLREMSTLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAEK
ASTAAEVMGLTANRLKELNLIDSIIEEPLGGAHRDFDAMAHNLKQRLLDDLKELEMLDEDNLLHRRYNRLMDYGYC

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=319, Percent_Identity=74.9216300940439, Blast_Score=501, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_PASMU (Q9CNX9)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245229.1
- ProteinModelPortal:   Q9CNX9
- SMR:   Q9CNX9
- GeneID:   1243639
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0292
- NMPDR:   fig|272843.1.peg.292
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   PMUL272843:PM0292-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35342; Mature: 35211

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQEYLDFELPIAELEAKIESLRSVASQDDEINLDDEIARLQKKSAELTKKTFANLDAWQ
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
VSKMARHPNRPYTLDYIERIFTEFEELAGDRAFADDKAIVGGLARLDGKPVMVIGHQKGR
HHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCC
SVKDKVKRNFGMPAPEGYRKALRLMQMAERFNLPIITFIDTPGAYPGVGAEERGQSEAIA
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHHHH
RNLREMSTLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAE
HHHHHHHHCCCEEEEEEEECCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHH
KASTAAEVMGLTANRLKELNLIDSIIEEPLGGAHRDFDAMAHNLKQRLLDDLKELEMLDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DNLLHRRYNRLMDYGYC
CHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AQEYLDFELPIAELEAKIESLRSVASQDDEINLDDEIARLQKKSAELTKKTFANLDAWQ
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
VSKMARHPNRPYTLDYIERIFTEFEELAGDRAFADDKAIVGGLARLDGKPVMVIGHQKGR
HHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCC
SVKDKVKRNFGMPAPEGYRKALRLMQMAERFNLPIITFIDTPGAYPGVGAEERGQSEAIA
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHHHH
RNLREMSTLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAE
HHHHHHHHCCCEEEEEEEECCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHH
KASTAAEVMGLTANRLKELNLIDSIIEEPLGGAHRDFDAMAHNLKQRLLDDLKELEMLDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DNLLHRRYNRLMDYGYC
CHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100