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The map label for this gene is dcuC [H]

Identifier: 15602095

GI number: 15602095

Start: 257316

End: 258665

Strand: Reverse

Name: dcuC [H]

Synonym: PM0230

Alternate gene names: 15602095

Gene position: 258665-257316 (Counterclockwise)

Preceding gene: 15602096

Following gene: 15602094

Centisome position: 11.46

GC content: 43.41

Gene sequence:

>1350_bases
ATGGATTTAATTATTGGCTTAATTGCCGTTATTCTCGTTGGTTATTACATTGTCAAAGGCTATTCTGCCACTGGCGTGCT
AATGACCGTCGGCTTATTGTTATTGCTTTGTAGTGTGTTATTAGACAAAGCCATTCTGCCGAACAGTGTCAAATCAACGG
GTAGTCTCTACCTCGATGTGTTTGAATATGTCAAATACCTTTTAATGAATCGTGGGGGCAACCTTGGTATGCTGATTATG
GTGTTGTGTGGTTTTGCGGCTTACATGACTCATATAGGGGCAAACGACATGGTAGTAAAACTCGCCTCCCAACCGCTCAA
ATACATCAAATCCCCTTATCTCTTAATGATTGTTGCTTATTTTCTTGCCTGTTTAATGTCATTAGCCGTTCCTTCTGCAA
CGGGATTAGGGGTCTTATTAATGGCAACACTGTTTCCTATCATGGTCAATGTGGGTATTTCACGCGGTGCCGCCGCCTCT
ATTTGTGCCTCCCCTGCTGCCATTATTCTGTCGCCCACTTCTGGTGATGTCGTACTTGCAGCAGAAGTATCAAAAATGCC
GTTATTAGATTTTGCTTTTCATCTCACCTTACCAATTTCCATTCTGACAATTATCTCTATCGCGATTGCCCATTTCTTTT
GGCAGCGTTACCTCGATCGTAAAGAGGGACATCGTGCAGAAATGTTAGCAGTGAGTGAAATCCAAACTTCAGCACCGCGT
TTTTATGCGATTTTACCCTTCACCCCCATTGTTGGCGTACTGGTCTTTGATGGCAAAATAGCACCAGAACTTCATATCAT
TACGATTATTGTCATTTGTTTACTCTTGGTCGCCCTGATCGATTTTTTAAGAACCTTTAGTGCGAAAAAAGTCTATGAAA
ACTTAAATGTTGCTTATCAAGGTATGGCGGATGCTTTCTCTGGCGTGGTGATTTTGCTTGTAGCCGCGGGTGTTTTTGCA
CAAGGATTGAGTACTATAGGCTTTATCCATGCCTTAATTGATTCCGTCCAATCAGTCAGCAGTGGTGGTTTCCTCATGAT
GCTCGCGCTAGCACTTATCACTGCACTAGCCGCAATTACCACTGGTTCAGGCAATGCCCCTTTCTATGCGTTTGTTGAAT
TAATTCCCAAATTAGCCGCCCATATGGGAATTAACCCGGCTTACCTAACCATTCCAATGTTACAAGCCTCCAATATTGGT
CGCAGCCTCTCACCAGTATCTGGTGTGGTTGTGGCAGTATCGGGCATGGCAAAAATCTCCCCATTTGAAGTGGTAAAACG
GATTTCAGTACCGATGTTAGTCGGACTCATTGTCGTGATTGTTGCGACAGAAATTATGGTGGTTGCCTAA

Upstream 100 bases:

>100_bases
ACACACATCTTTTTGCTAACCCCGCTGACATTGCGCAAAAAATTAAACAATTAATCGGATAGCGCAATATTCGACTTATC
TTATTAAATGGAGATTAATT

Downstream 100 bases:

>100_bases
TACTGTCGTTTGACTTATGTCAGTTGTACACATACAATAAAACGTATTTGGTACGCTTTAAACAGCCAATCGGCACAACT
GAACAGATTGTTAGCCGTAC

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MDLIIGLIAVILVGYYIVKGYSATGVLMTVGLLLLLCSVLLDKAILPNSVKSTGSLYLDVFEYVKYLLMNRGGNLGMLIM
VLCGFAAYMTHIGANDMVVKLASQPLKYIKSPYLLMIVAYFLACLMSLAVPSATGLGVLLMATLFPIMVNVGISRGAAAS
ICASPAAIILSPTSGDVVLAAEVSKMPLLDFAFHLTLPISILTIISIAIAHFFWQRYLDRKEGHRAEMLAVSEIQTSAPR
FYAILPFTPIVGVLVFDGKIAPELHIITIIVICLLLVALIDFLRTFSAKKVYENLNVAYQGMADAFSGVVILLVAAGVFA
QGLSTIGFIHALIDSVQSVSSGGFLMMLALALITALAAITTGSGNAPFYAFVELIPKLAAHMGINPAYLTIPMLQASNIG
RSLSPVSGVVVAVSGMAKISPFEVVKRISVPMLVGLIVVIVATEIMVVA

Sequences:

>Translated_449_residues
MDLIIGLIAVILVGYYIVKGYSATGVLMTVGLLLLLCSVLLDKAILPNSVKSTGSLYLDVFEYVKYLLMNRGGNLGMLIM
VLCGFAAYMTHIGANDMVVKLASQPLKYIKSPYLLMIVAYFLACLMSLAVPSATGLGVLLMATLFPIMVNVGISRGAAAS
ICASPAAIILSPTSGDVVLAAEVSKMPLLDFAFHLTLPISILTIISIAIAHFFWQRYLDRKEGHRAEMLAVSEIQTSAPR
FYAILPFTPIVGVLVFDGKIAPELHIITIIVICLLLVALIDFLRTFSAKKVYENLNVAYQGMADAFSGVVILLVAAGVFA
QGLSTIGFIHALIDSVQSVSSGGFLMMLALALITALAAITTGSGNAPFYAFVELIPKLAAHMGINPAYLTIPMLQASNIG
RSLSPVSGVVVAVSGMAKISPFEVVKRISVPMLVGLIVVIVATEIMVVA
>Mature_449_residues
MDLIIGLIAVILVGYYIVKGYSATGVLMTVGLLLLLCSVLLDKAILPNSVKSTGSLYLDVFEYVKYLLMNRGGNLGMLIM
VLCGFAAYMTHIGANDMVVKLASQPLKYIKSPYLLMIVAYFLACLMSLAVPSATGLGVLLMATLFPIMVNVGISRGAAAS
ICASPAAIILSPTSGDVVLAAEVSKMPLLDFAFHLTLPISILTIISIAIAHFFWQRYLDRKEGHRAEMLAVSEIQTSAPR
FYAILPFTPIVGVLVFDGKIAPELHIITIIVICLLLVALIDFLRTFSAKKVYENLNVAYQGMADAFSGVVILLVAAGVFA
QGLSTIGFIHALIDSVQSVSSGGFLMMLALALITALAAITTGSGNAPFYAFVELIPKLAAHMGINPAYLTIPMLQASNIG
RSLSPVSGVVVAVSGMAKISPFEVVKRISVPMLVGLIVVIVATEIMVVA

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=432, Percent_Identity=74.0740740740741, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI1789622, Length=450, Percent_Identity=37.3333333333333, Blast_Score=304, Evalue=6e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 47621; Mature: 47621

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIIGLIAVILVGYYIVKGYSATGVLMTVGLLLLLCSVLLDKAILPNSVKSTGSLYLDV
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FEYVKYLLMNRGGNLGMLIMVLCGFAAYMTHIGANDMVVKLASQPLKYIKSPYLLMIVAY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
FLACLMSLAVPSATGLGVLLMATLFPIMVNVGISRGAAASICASPAAIILSPTSGDVVLA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEEE
AEVSKMPLLDFAFHLTLPISILTIISIAIAHFFWQRYLDRKEGHRAEMLAVSEIQTSAPR
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
FYAILPFTPIVGVLVFDGKIAPELHIITIIVICLLLVALIDFLRTFSAKKVYENLNVAYQ
EEEEECHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMADAFSGVVILLVAAGVFAQGLSTIGFIHALIDSVQSVSSGGFLMMLALALITALAAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TGSGNAPFYAFVELIPKLAAHMGINPAYLTIPMLQASNIGRSLSPVSGVVVAVSGMAKIS
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCCHHHHHHHCCCCCCCC
PFEVVKRISVPMLVGLIVVIVATEIMVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLIIGLIAVILVGYYIVKGYSATGVLMTVGLLLLLCSVLLDKAILPNSVKSTGSLYLDV
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FEYVKYLLMNRGGNLGMLIMVLCGFAAYMTHIGANDMVVKLASQPLKYIKSPYLLMIVAY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
FLACLMSLAVPSATGLGVLLMATLFPIMVNVGISRGAAASICASPAAIILSPTSGDVVLA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEEE
AEVSKMPLLDFAFHLTLPISILTIISIAIAHFFWQRYLDRKEGHRAEMLAVSEIQTSAPR
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
FYAILPFTPIVGVLVFDGKIAPELHIITIIVICLLLVALIDFLRTFSAKKVYENLNVAYQ
EEEEECHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMADAFSGVVILLVAAGVFAQGLSTIGFIHALIDSVQSVSSGGFLMMLALALITALAAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TGSGNAPFYAFVELIPKLAAHMGINPAYLTIPMLQASNIGRSLSPVSGVVVAVSGMAKIS
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCCHHHHHHHCCCCCCCC
PFEVVKRISVPMLVGLIVVIVATEIMVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]