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The map label for this gene is rbsK [H]

Identifier: 15602017

GI number: 15602017

Start: 179679

End: 180599

Strand: Reverse

Name: rbsK [H]

Synonym: PM0152

Alternate gene names: 15602017

Gene position: 180599-179679 (Counterclockwise)

Preceding gene: 15602018

Following gene: 15602016

Centisome position: 8.0

GC content: 45.28

Gene sequence:

>921_bases
ATGAAAAAATTAACGGTACTTGGCAGTGTAAATGCCGATCATGTCATTTCTGTCCCACACTTTGCTAAACCCGGTGAAAC
CCTCACAGGCAATCATTACCATATTGCGTATGGAGGAAAAGGTGCAAACCAAGCTGTTGCGGCTGCTCGCTTAGGTGCCA
ATATTGATTTTATTGCTTGTATTGGTGATGATGCGATTGGACAAGCAATGAAAAAGGCTTTCCAACAAGATGGCATTAAT
ACACAAGCCGTTGTAGAAATTGCCGATCAAATGACAGGAATCGCCATGATTCAAGTCAACGCACACGGGGAAAACAGTAT
TGTCATTGCCGCCGGAGCAAATGCTTATTTAACGGAAACTGTCGTTGAACAATTTGCGGATAAAATTACGCAAGCGGATA
CTTTATTAATGCAACTTGAAACCCCTTTAAGAGCGGTCATTTTCGCGGCAAAATTGGCTAAATCAGCCAATACTAAAGTG
GTGTTAAATCCGGCACCGGCCCAGCCACTTCCCGATGAGTTACTCACGCAATTGGACATGATTACCCCTAATGAAACAGA
GACTGAAATCTTGACTGGGGTGAAGGTCGTTGACGAACATTCTGCTGCGCAAGCGGCGGCTCTCTTTCATCAAAAAGGCA
TTGAAACGGTGCTCATCACTTTAGGCTCAAAAGGGGTTTATGCAAGTCAGAAAGGTACGCCGGGCAAAATGGTCGCAGGC
TTTCGTGTCGATGCGAAAGACACAACTGCCGCAGGTGATACGTTTAATGGCGCTTTAATGACTGCATTGTTAGAAGATAA
ACCGCTTGCTGATGCCATCCGTTTTGCTCATGCTGCCGCAGCAATTAGCGTCACCAGAGCGGGCGCACAACCCTCAATTC
CGACTAGACAAGAAACCCTCAACTTTTTACAATCACATTAA

Upstream 100 bases:

>100_bases
AAGTGATCCATAAATAAGATCATCATCAAGCTTCGATGGGGGCAAGCTTAGGGCTTGCCCTATATCACCTCAACATGAAA
CACAAAATAGCGAAGAACAT

Downstream 100 bases:

>100_bases
AATCATGTAGGGGAAACTTACCCCTACTTTTTCACGTTTTCAATGACCTAGCAACATTCGCTACACGATAAGAGAAACTA
CAATGGCAACTATGAAAGAC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKKLTVLGSVNADHVISVPHFAKPGETLTGNHYHIAYGGKGANQAVAAARLGANIDFIACIGDDAIGQAMKKAFQQDGIN
TQAVVEIADQMTGIAMIQVNAHGENSIVIAAGANAYLTETVVEQFADKITQADTLLMQLETPLRAVIFAAKLAKSANTKV
VLNPAPAQPLPDELLTQLDMITPNETETEILTGVKVVDEHSAAQAAALFHQKGIETVLITLGSKGVYASQKGTPGKMVAG
FRVDAKDTTAAGDTFNGALMTALLEDKPLADAIRFAHAAAAISVTRAGAQPSIPTRQETLNFLQSH

Sequences:

>Translated_306_residues
MKKLTVLGSVNADHVISVPHFAKPGETLTGNHYHIAYGGKGANQAVAAARLGANIDFIACIGDDAIGQAMKKAFQQDGIN
TQAVVEIADQMTGIAMIQVNAHGENSIVIAAGANAYLTETVVEQFADKITQADTLLMQLETPLRAVIFAAKLAKSANTKV
VLNPAPAQPLPDELLTQLDMITPNETETEILTGVKVVDEHSAAQAAALFHQKGIETVLITLGSKGVYASQKGTPGKMVAG
FRVDAKDTTAAGDTFNGALMTALLEDKPLADAIRFAHAAAAISVTRAGAQPSIPTRQETLNFLQSH
>Mature_306_residues
MKKLTVLGSVNADHVISVPHFAKPGETLTGNHYHIAYGGKGANQAVAAARLGANIDFIACIGDDAIGQAMKKAFQQDGIN
TQAVVEIADQMTGIAMIQVNAHGENSIVIAAGANAYLTETVVEQFADKITQADTLLMQLETPLRAVIFAAKLAKSANTKV
VLNPAPAQPLPDELLTQLDMITPNETETEILTGVKVVDEHSAAQAAALFHQKGIETVLITLGSKGVYASQKGTPGKMVAG
FRVDAKDTTAAGDTFNGALMTALLEDKPLADAIRFAHAAAAISVTRAGAQPSIPTRQETLNFLQSH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=295, Percent_Identity=37.6271186440678, Blast_Score=170, Evalue=2e-42,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=60.6666666666667, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=30.6930693069307, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87081971, Length=279, Percent_Identity=29.7491039426523, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788491, Length=252, Percent_Identity=25, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788484, Length=294, Percent_Identity=24.4897959183673, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17532905, Length=308, Percent_Identity=37.3376623376623, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319884, Length=326, Percent_Identity=28.8343558282209, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=35.0993377483444, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24583886, Length=309, Percent_Identity=32.0388349514563, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32073; Mature: 32073

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTVLGSVNADHVISVPHFAKPGETLTGNHYHIAYGGKGANQAVAAARLGANIDFIAC
CCEEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEE
IGDDAIGQAMKKAFQQDGINTQAVVEIADQMTGIAMIQVNAHGENSIVIAAGANAYLTET
ECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCHHHHHH
VVEQFADKITQADTLLMQLETPLRAVIFAAKLAKSANTKVVLNPAPAQPLPDELLTQLDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHC
ITPNETETEILTGVKVVDEHSAAQAAALFHQKGIETVLITLGSKGVYASQKGTPGKMVAG
CCCCCCHHHHHHCCCEECCHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCCEEEE
FRVDAKDTTAAGDTFNGALMTALLEDKPLADAIRFAHAAAAISVTRAGAQPSIPTRQETL
EEECCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHH
NFLQSH
HHHHCC
>Mature Secondary Structure
MKKLTVLGSVNADHVISVPHFAKPGETLTGNHYHIAYGGKGANQAVAAARLGANIDFIAC
CCEEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEE
IGDDAIGQAMKKAFQQDGINTQAVVEIADQMTGIAMIQVNAHGENSIVIAAGANAYLTET
ECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCHHHHHH
VVEQFADKITQADTLLMQLETPLRAVIFAAKLAKSANTKVVLNPAPAQPLPDELLTQLDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHC
ITPNETETEILTGVKVVDEHSAAQAAALFHQKGIETVLITLGSKGVYASQKGTPGKMVAG
CCCCCCHHHHHHCCCEECCHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCCEEEE
FRVDAKDTTAAGDTFNGALMTALLEDKPLADAIRFAHAAAAISVTRAGAQPSIPTRQETL
EEECCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHH
NFLQSH
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]