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The map label for this gene is fecC [H]

Identifier: 15601995

GI number: 15601995

Start: 153911

End: 154894

Strand: Reverse

Name: fecC [H]

Synonym: PM0130

Alternate gene names: 15601995

Gene position: 154894-153911 (Counterclockwise)

Preceding gene: 15601996

Following gene: 15601994

Centisome position: 6.86

GC content: 45.53

Gene sequence:

>984_bases
ATGAAAACCTTTCTACGTTGGAGCTTCCCCACCGGCATCTTATTTGGGCTTTTGTGGGGAAGCTTATTTTTATACTACCC
AACCCCGATTTCAGCGTGGGAAACCCTTCAGGCATTCATCGGACTCGACGATGAATTAGTCCAAATCACTATCCTCGATT
TACGCTTACCTCGCTCTTTAGTTGCCATAGCGATGGGCGCTAATTTGGCCGTCGCAGGCGCATTGTTACAAACTATCACG
CGTAATCCCTTAGCCTCGCCTTCGTTATTAAGTGTCAATGCAGGTGCAAGCTTAGCGATGGTAACAGCAACGGCGGTCAT
GCCTAGTTTTTTCTCAGGTTATAGCATTGCCTTCATTTCCAGTATTGGTGGAGGATTAAGCTGGTTATTAGTGATGCTGA
TTAGTGGTGGATGGCATGCACGTGCAGAACGCAACCGCGTAATTCTGGCAGGGATTGCCGTGTCTTTATTTTGTGCTGCA
TTAACAAAATTAGTGATTATTATTGCTGAAGATCATGCTGCGAATATCATGAATTGGCTTGCTGGTGGAATAGCCCATGC
GCGTTGGGGAGAATGGTGGATCATTTTACCGTTTTTCGTGTTAAGCCTGCTTTTTTGTACGTTCTTTGCTAGCCAACTGA
ATTTGCTCAATCTGAGTGATGAATCTGCACAATCACTTGGGGTTAATCTGTTTAAGCTACGTTGGATGACAAATATTGTG
GCACTCCTGATCATTGGCTCCAGTGTCAGTGTCGCCGGTCCGGTGGCCTTTATTGGTCTATTAATTCCTCATTTAGCACG
TTATTGGATCAGTTATGATTTACGCAAGATGCTCCCAATGTCAATGTTATTGGGAGGTTGTCTGATGCTTATCGCAGACA
TGTTAGCCCGTGCAGTCACGTTTCCAAATGAAATCCCTGCGGGCGCGATCCTCGCTTTAGTCGGCGCACCTGTTTTTGTC
TTATTTGCGCGAGGAAAACGATAA

Upstream 100 bases:

>100_bases
TCTTAGCTAATGATAATTTATGGGCAAGAGCACGTGGTATTGATGCCGCTGAAGTAATGGCTAAAGAAGTCCAAGACTTT
GTAACGAAATCCGCCAAATA

Downstream 100 bases:

>100_bases
TGGCAGCCAATAGCAAACCACTTACACGCTTTAAAATACCTTTTTATCCAACCGCACTTTTGCTGTTGTTGATACTCTTT
TGTTTAAGTTTACAGCTAGG

Product: iron-dicitrate transporter permease subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron(III) dicitrate transport system permease protein fecC [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKTFLRWSFPTGILFGLLWGSLFLYYPTPISAWETLQAFIGLDDELVQITILDLRLPRSLVAIAMGANLAVAGALLQTIT
RNPLASPSLLSVNAGASLAMVTATAVMPSFFSGYSIAFISSIGGGLSWLLVMLISGGWHARAERNRVILAGIAVSLFCAA
LTKLVIIIAEDHAANIMNWLAGGIAHARWGEWWIILPFFVLSLLFCTFFASQLNLLNLSDESAQSLGVNLFKLRWMTNIV
ALLIIGSSVSVAGPVAFIGLLIPHLARYWISYDLRKMLPMSMLLGGCLMLIADMLARAVTFPNEIPAGAILALVGAPVFV
LFARGKR

Sequences:

>Translated_327_residues
MKTFLRWSFPTGILFGLLWGSLFLYYPTPISAWETLQAFIGLDDELVQITILDLRLPRSLVAIAMGANLAVAGALLQTIT
RNPLASPSLLSVNAGASLAMVTATAVMPSFFSGYSIAFISSIGGGLSWLLVMLISGGWHARAERNRVILAGIAVSLFCAA
LTKLVIIIAEDHAANIMNWLAGGIAHARWGEWWIILPFFVLSLLFCTFFASQLNLLNLSDESAQSLGVNLFKLRWMTNIV
ALLIIGSSVSVAGPVAFIGLLIPHLARYWISYDLRKMLPMSMLLGGCLMLIADMLARAVTFPNEIPAGAILALVGAPVFV
LFARGKR
>Mature_327_residues
MKTFLRWSFPTGILFGLLWGSLFLYYPTPISAWETLQAFIGLDDELVQITILDLRLPRSLVAIAMGANLAVAGALLQTIT
RNPLASPSLLSVNAGASLAMVTATAVMPSFFSGYSIAFISSIGGGLSWLLVMLISGGWHARAERNRVILAGIAVSLFCAA
LTKLVIIIAEDHAANIMNWLAGGIAHARWGEWWIILPFFVLSLLFCTFFASQLNLLNLSDESAQSLGVNLFKLRWMTNIV
ALLIIGSSVSVAGPVAFIGLLIPHLARYWISYDLRKMLPMSMLLGGCLMLIADMLARAVTFPNEIPAGAILALVGAPVFV
LFARGKR

Specific function: Part of the binding-protein-dependent transport system for citrate-dependent Fe(3+). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=323, Percent_Identity=52.9411764705882, Blast_Score=313, Evalue=8e-87,
Organism=Escherichia coli, GI1790740, Length=274, Percent_Identity=36.8613138686131, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786805, Length=295, Percent_Identity=32.8813559322034, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788004, Length=274, Percent_Identity=32.4817518248175, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=29.4545454545455, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786804, Length=299, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35368; Mature: 35368

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFLRWSFPTGILFGLLWGSLFLYYPTPISAWETLQAFIGLDDELVQITILDLRLPRSL
CCCEEEECCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCHHEEEEEEEHHCCHHH
VAIAMGANLAVAGALLQTITRNPLASPSLLSVNAGASLAMVTATAVMPSFFSGYSIAFIS
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHH
SIGGGLSWLLVMLISGGWHARAERNRVILAGIAVSLFCAALTKLVIIIAEDHAANIMNWL
HCCCHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHEEEEECCHHHHHHHHH
AGGIAHARWGEWWIILPFFVLSLLFCTFFASQLNLLNLSDESAQSLGVNLFKLRWMTNIV
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHCCHHHHHHHHHHHH
ALLIIGSSVSVAGPVAFIGLLIPHLARYWISYDLRKMLPMSMLLGGCLMLIADMLARAVT
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPNEIPAGAILALVGAPVFVLFARGKR
CCCCCCHHHHHHHHHHHHEEHEECCCC
>Mature Secondary Structure
MKTFLRWSFPTGILFGLLWGSLFLYYPTPISAWETLQAFIGLDDELVQITILDLRLPRSL
CCCEEEECCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCHHEEEEEEEHHCCHHH
VAIAMGANLAVAGALLQTITRNPLASPSLLSVNAGASLAMVTATAVMPSFFSGYSIAFIS
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHH
SIGGGLSWLLVMLISGGWHARAERNRVILAGIAVSLFCAALTKLVIIIAEDHAANIMNWL
HCCCHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHEEEEECCHHHHHHHHH
AGGIAHARWGEWWIILPFFVLSLLFCTFFASQLNLLNLSDESAQSLGVNLFKLRWMTNIV
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHCCHHHHHHHHHHHH
ALLIIGSSVSVAGPVAFIGLLIPHLARYWISYDLRKMLPMSMLLGGCLMLIADMLARAVT
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPNEIPAGAILALVGAPVFVLFARGKR
CCCCCCHHHHHHHHHHHHEEHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2651410; 7610040; 9278503 [H]