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The map label for this gene is fecD [H]

Identifier: 15601994

GI number: 15601994

Start: 152919

End: 153911

Strand: Reverse

Name: fecD [H]

Synonym: PM0129

Alternate gene names: 15601994

Gene position: 153911-152919 (Counterclockwise)

Preceding gene: 15601995

Following gene: 15601993

Centisome position: 6.82

GC content: 45.42

Gene sequence:

>993_bases
ATGGCAGCCAATAGCAAACCACTTACACGCTTTAAAATACCTTTTTATCCAACCGCACTTTTGCTGTTGTTGATACTCTT
TTGTTTAAGTTTACAGCTAGGCACCTATCATCTCTCTATCAGTGAAATTTGGCAGATTTTACATCACCCTGAAGACGCCA
ATCACTTTACGTTAATGGAATATCGTTTGCCACGTGCCTTGCTCGCGATCTTAATGGGCAGTGCCTTAGCAGTTTCTGGC
GTATTAGTGCAAAGTGTGGTGAGAAATCCCCTCGCCTCGCCAGATATTCTCGGTATCAACAACGCGGCAGGGCTAGTCGC
AGTGATTAGCTTGATTTATTTCCCGGGACTTGCTTTTTACTGGTTACCTATTTTTGCCTTTATTGGTGGCATTTTGTCTT
TTCTGCTACTTTGGCTTATTTGTGGTTTACATTTTCGTCCACTTAAAATGGCAATTATTGGGGTCGCGCTGTCTGCCTTA
TGGGCTGCAGCAAGCCACTATCTAATGCTATCCAATCCAGTTGATATTAACTCCGCGATGTTATGGTTAACCGGCAGCCT
ATGGGGACGGAGTTGGTCTTACTTATTGGTGGTGTTACCTTGGTTGCTTGTGCTACTGCCTTTGGCTTTTCTGTTCTGTC
GTGATCTGGATACCTTAGCATTAGGCGAAAACAAAGCCGCCACTTTAGGGGTATCCCTTCACAAAATGCAGATCATCGTG
TTGCTACTTTCTGTGGCGCTTGCCACCACCGCGGTTGCGATTTGTGGTCCAATCGCATTTCTCGGCTTAGTCGCACCGCA
CTTTGCTCGCCATTTAGTCGGCGGTCGTCATCGAACCTTATTGCCAGCGGCATTACTGTTAGGGGCAATTTTACTGCTGA
TTTCAGATATTTTAGCCCGCATTATTGCTCCCCCTGTGGAGATTCCCGCTGGGGTCCTCACCGCAATTTTAGGGGCACCA
TATTTTTTCTATTTATTAATGAGAACGAAATAA

Upstream 100 bases:

>100_bases
TAGCCCGTGCAGTCACGTTTCCAAATGAAATCCCTGCGGGCGCGATCCTCGCTTTAGTCGGCGCACCTGTTTTTGTCTTA
TTTGCGCGAGGAAAACGATA

Downstream 100 bases:

>100_bases
TGAGCTTAACCGTAGAACATTTACAACTGGCGTATCAAGATAAAACCATTGTCTCTAATCTCAATTTGCGCTTGCCGAGT
AACAAAGTCATTGCGTTAAT

Product: iron-dicitrate transporter subunit FecD

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron(III) dicitrate transport system permease protein fecD [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MAANSKPLTRFKIPFYPTALLLLLILFCLSLQLGTYHLSISEIWQILHHPEDANHFTLMEYRLPRALLAILMGSALAVSG
VLVQSVVRNPLASPDILGINNAAGLVAVISLIYFPGLAFYWLPIFAFIGGILSFLLLWLICGLHFRPLKMAIIGVALSAL
WAAASHYLMLSNPVDINSAMLWLTGSLWGRSWSYLLVVLPWLLVLLPLAFLFCRDLDTLALGENKAATLGVSLHKMQIIV
LLLSVALATTAVAICGPIAFLGLVAPHFARHLVGGRHRTLLPAALLLGAILLLISDILARIIAPPVEIPAGVLTAILGAP
YFFYLLMRTK

Sequences:

>Translated_330_residues
MAANSKPLTRFKIPFYPTALLLLLILFCLSLQLGTYHLSISEIWQILHHPEDANHFTLMEYRLPRALLAILMGSALAVSG
VLVQSVVRNPLASPDILGINNAAGLVAVISLIYFPGLAFYWLPIFAFIGGILSFLLLWLICGLHFRPLKMAIIGVALSAL
WAAASHYLMLSNPVDINSAMLWLTGSLWGRSWSYLLVVLPWLLVLLPLAFLFCRDLDTLALGENKAATLGVSLHKMQIIV
LLLSVALATTAVAICGPIAFLGLVAPHFARHLVGGRHRTLLPAALLLGAILLLISDILARIIAPPVEIPAGVLTAILGAP
YFFYLLMRTK
>Mature_329_residues
AANSKPLTRFKIPFYPTALLLLLILFCLSLQLGTYHLSISEIWQILHHPEDANHFTLMEYRLPRALLAILMGSALAVSGV
LVQSVVRNPLASPDILGINNAAGLVAVISLIYFPGLAFYWLPIFAFIGGILSFLLLWLICGLHFRPLKMAIIGVALSALW
AAASHYLMLSNPVDINSAMLWLTGSLWGRSWSYLLVVLPWLLVLLPLAFLFCRDLDTLALGENKAATLGVSLHKMQIIVL
LLSVALATTAVAICGPIAFLGLVAPHFARHLVGGRHRTLLPAALLLGAILLLISDILARIIAPPVEIPAGVLTAILGAPY
FFYLLMRTK

Specific function: Part of the binding-protein-dependent transport system for citrate-dependent Fe(3+). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=55.4006968641115, Blast_Score=299, Evalue=1e-82,
Organism=Escherichia coli, GI1790741, Length=335, Percent_Identity=33.134328358209, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786804, Length=317, Percent_Identity=34.384858044164, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786805, Length=303, Percent_Identity=35.6435643564356, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786347, Length=296, Percent_Identity=33.445945945946, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788004, Length=275, Percent_Identity=35.6363636363636, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35920; Mature: 35789

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANSKPLTRFKIPFYPTALLLLLILFCLSLQLGTYHLSISEIWQILHHPEDANHFTLME
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCCCCEEHHH
YRLPRALLAILMGSALAVSGVLVQSVVRNPLASPDILGINNAAGLVAVISLIYFPGLAFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
WLPIFAFIGGILSFLLLWLICGLHFRPLKMAIIGVALSALWAAASHYLMLSNPVDINSAM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHH
LWLTGSLWGRSWSYLLVVLPWLLVLLPLAFLFCRDLDTLALGENKAATLGVSLHKMQIIV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHH
LLLSVALATTAVAICGPIAFLGLVAPHFARHLVGGRHRTLLPAALLLGAILLLISDILAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IIAPPVEIPAGVLTAILGAPYFFYLLMRTK
HCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AANSKPLTRFKIPFYPTALLLLLILFCLSLQLGTYHLSISEIWQILHHPEDANHFTLME
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCCCCEEHHH
YRLPRALLAILMGSALAVSGVLVQSVVRNPLASPDILGINNAAGLVAVISLIYFPGLAFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
WLPIFAFIGGILSFLLLWLICGLHFRPLKMAIIGVALSALWAAASHYLMLSNPVDINSAM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHH
LWLTGSLWGRSWSYLLVVLPWLLVLLPLAFLFCRDLDTLALGENKAATLGVSLHKMQIIV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHH
LLLSVALATTAVAICGPIAFLGLVAPHFARHLVGGRHRTLLPAALLLGAILLLISDILAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IIAPPVEIPAGVLTAILGAPYFFYLLMRTK
HCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2651410; 7610040; 9278503 [H]