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The map label for this gene is xerD

Identifier: 15601958

GI number: 15601958

Start: 118281

End: 119174

Strand: Reverse

Name: xerD

Synonym: PM0093

Alternate gene names: 15601958

Gene position: 119174-118281 (Counterclockwise)

Preceding gene: 15601959

Following gene: 15601948

Centisome position: 5.28

GC content: 40.27

Gene sequence:

>894_bases
ATGAAAGATTCCGCGTTAATTGAGCTTTTTCTAAATGAAATTTGGATCGAAAAGCAACTCTCGCAAAATACGATTGCCTC
TTATCGCTTAGATTTGACTGCACTCATTCAATGGCTAGAAAAACAACAATTAACGCTTATCAATCTGGATGCCATCGACT
TACAAACATTTCTAGGTGAACGCTTAAACCAAGGCTACAAAGCCACCAGCACAGCTCGCCTACTCAGTGCGATGCGAAAA
TTATTTCAATACTTATACCGCGAAAAATACCGCACAGATGATCCCAGTGCGGTATTAAGTTCTCCCAAATTACCTAGCCG
CTTGCCTAAATACCTAACGGAACAACAAGTTACTGATTTACTGAACTCTCCTGATGTCGATATCCCCTTAGAATTACGCG
ATAAAGCCATGATGGAATTGCTTTATGCAACAGGATTACGGGTCACTGAATTAGTGTCGTTGACTATTGAAAACATAAAT
ATTAATCAGGGGATTGTACGGGTTGTTGGTAAAGGAAACAAAGAACGGATTGTTCCCATTGGGGAAGAAGCAACTTATTG
GATTCGTCAATTTATGCTATATGGGCGTCCTTTTTTATTGCATGGACAAAGCTCAGATGTCGTCTTCCCAAGTAAAAGAG
CGCTACAAATGACACGCCAAACCTTTTGGCACCGTATTAAACATTATGCGCTTTTGAGTGACATTGATATCAATAGCTTA
TCGCCCCATGTACTGCGTCACGCTTTTGCTACACATTTAGTAAATCATGGTGCGGATTTGCGTGTAGTACAAATGTTACT
CGGACACAGCGATTTATCCACAACACAAATTTATACTCACGTTGCTAAAGAGCGTTTAAAACATTTACATGAACGCTACC
ATCCAAGGGGCTAA

Upstream 100 bases:

>100_bases
CTCCCACAATTACGTTCCTTGCGATGACAGGTGTTGCAGCTTTGGCATTCGTCGTGATTCCACGTAAAGTCGATGCCTTT
TTACTTAAACGGTGCTAAAC

Downstream 100 bases:

>100_bases
CATCAAGCATAAAAAAACTGCATCACAAGGATGCAGTTTTAACGTTGGATAACAGGATTAGAAAGAATCTTTTAAGCGTT
CATCGGCACGACGCGCTTCG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKDSALIELFLNEIWIEKQLSQNTIASYRLDLTALIQWLEKQQLTLINLDAIDLQTFLGERLNQGYKATSTARLLSAMRK
LFQYLYREKYRTDDPSAVLSSPKLPSRLPKYLTEQQVTDLLNSPDVDIPLELRDKAMMELLYATGLRVTELVSLTIENIN
INQGIVRVVGKGNKERIVPIGEEATYWIRQFMLYGRPFLLHGQSSDVVFPSKRALQMTRQTFWHRIKHYALLSDIDINSL
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKERLKHLHERYHPRG

Sequences:

>Translated_297_residues
MKDSALIELFLNEIWIEKQLSQNTIASYRLDLTALIQWLEKQQLTLINLDAIDLQTFLGERLNQGYKATSTARLLSAMRK
LFQYLYREKYRTDDPSAVLSSPKLPSRLPKYLTEQQVTDLLNSPDVDIPLELRDKAMMELLYATGLRVTELVSLTIENIN
INQGIVRVVGKGNKERIVPIGEEATYWIRQFMLYGRPFLLHGQSSDVVFPSKRALQMTRQTFWHRIKHYALLSDIDINSL
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKERLKHLHERYHPRG
>Mature_297_residues
MKDSALIELFLNEIWIEKQLSQNTIASYRLDLTALIQWLEKQQLTLINLDAIDLQTFLGERLNQGYKATSTARLLSAMRK
LFQYLYREKYRTDDPSAVLSSPKLPSRLPKYLTEQQVTDLLNSPDVDIPLELRDKAMMELLYATGLRVTELVSLTIENIN
INQGIVRVVGKGNKERIVPIGEEATYWIRQFMLYGRPFLLHGQSSDVVFPSKRALQMTRQTFWHRIKHYALLSDIDINSL
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKERLKHLHERYHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=67.5675675675676, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=35.958904109589, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1790768, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERD_PASMU (Q9CPF0)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245030.1
- ProteinModelPortal:   Q9CPF0
- SMR:   Q9CPF0
- GeneID:   1243440
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0093
- NMPDR:   fig|272843.1.peg.93
- HOGENOM:   HBG727654
- OMA:   LMERELY
- ProtClustDB:   PRK00283
- BioCyc:   PMUL272843:PM0093-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01807
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02225

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34369; Mature: 34369

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: ACT_SITE 147-147 ACT_SITE 171-171 ACT_SITE 243-243 ACT_SITE 246-246 ACT_SITE 269-269 ACT_SITE 278-278

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSALIELFLNEIWIEKQLSQNTIASYRLDLTALIQWLEKQQLTLINLDAIDLQTFLGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHH
RLNQGYKATSTARLLSAMRKLFQYLYREKYRTDDPSAVLSSPKLPSRLPKYLTEQQVTDL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
LNSPDVDIPLELRDKAMMELLYATGLRVTELVSLTIENININQGIVRVVGKGNKERIVPI
HCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHEECCCCCCCEEEC
GEEATYWIRQFMLYGRPFLLHGQSSDVVFPSKRALQMTRQTFWHRIKHYALLSDIDINSL
CCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKERLKHLHERYHPRG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKDSALIELFLNEIWIEKQLSQNTIASYRLDLTALIQWLEKQQLTLINLDAIDLQTFLGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHH
RLNQGYKATSTARLLSAMRKLFQYLYREKYRTDDPSAVLSSPKLPSRLPKYLTEQQVTDL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
LNSPDVDIPLELRDKAMMELLYATGLRVTELVSLTIENININQGIVRVVGKGNKERIVPI
HCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHEECCCCCCCEEEC
GEEATYWIRQFMLYGRPFLLHGQSSDVVFPSKRALQMTRQTFWHRIKHYALLSDIDINSL
CCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKERLKHLHERYHPRG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100