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The map label for this gene is rppH

Identifier: 15601947

GI number: 15601947

Start: 109062

End: 109658

Strand: Reverse

Name: rppH

Synonym: PM0082

Alternate gene names: 15601947

Gene position: 109658-109062 (Counterclockwise)

Preceding gene: 15601948

Following gene: 15601946

Centisome position: 4.86

GC content: 37.86

Gene sequence:

>597_bases
GTGATCGATTTCGATGGCTACCGTCCGAATGTAGGTATTGTCATTTGCAATAGTAAAGGACAAGTACTTTGGGCTAAAAG
ATACGGACAAAATTCTTGGCAATTTCCTCAAGGCGGCATTAATGACAATGAAAGCGCCGAGCAAGCCATGTATCGGGAAT
TGTTTGAAGAAGTTGGCTTATCGCCTAAAGATGTCAAAATATTATATATTTCAAAACATTGGTTACGTTATAAATTACCA
AAACGTTTGTTACGTTACGACAGCAAACCCGTGTGTATCGGTCAAAAACAACGTTGGTTTCTATTGCAGCTGGTTTCCGA
TGAAAAAAATATCAACATGCAATCCAGTAAATCACCTGAATTTGATGGTTGGCGCTGGGTCAGCTTCTGGTATCCTGTCC
GCCAAGTCGTGTCTTTTAAAAAAGAAGTGTATCGTAAAGCAATGAAAGAATTTGCTTCAGTCCTCTTTGATGGGGCGAAA
GAAAATCTTTTATCGAGCAAAAGCAATGAAAGTGATTTAAAGACACATCACACAACAAAAAAATCCACATTTTTAACCAA
GCACTCAAAAAAACATTTTCATAAATCAAGGGGTTGA

Upstream 100 bases:

>100_bases
TTGTGCTTAATTGGATTATCAGTTGAGAAAATCATGATTATATGAAACAATCGACAGATTATTTTATGATGAATTAAATA
GATAGATTAAAGGAGCGCTA

Downstream 100 bases:

>100_bases
GTATGTTCACCTTTTTTCTTATATGCCTGGCGGTTGGTGCATTTGCAGGCTTTTTAGCCGGTCTTTTTGGCATCGGTGGC
GGTCTTGTCATTGTACCTGT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIDFDGYRPNVGIVICNSKGQVLWAKRYGQNSWQFPQGGINDNESAEQAMYRELFEEVGLSPKDVKILYISKHWLRYKLP
KRLLRYDSKPVCIGQKQRWFLLQLVSDEKNINMQSSKSPEFDGWRWVSFWYPVRQVVSFKKEVYRKAMKEFASVLFDGAK
ENLLSSKSNESDLKTHHTTKKSTFLTKHSKKHFHKSRG

Sequences:

>Translated_198_residues
MIDFDGYRPNVGIVICNSKGQVLWAKRYGQNSWQFPQGGINDNESAEQAMYRELFEEVGLSPKDVKILYISKHWLRYKLP
KRLLRYDSKPVCIGQKQRWFLLQLVSDEKNINMQSSKSPEFDGWRWVSFWYPVRQVVSFKKEVYRKAMKEFASVLFDGAK
ENLLSSKSNESDLKTHHTTKKSTFLTKHSKKHFHKSRG
>Mature_198_residues
MIDFDGYRPNVGIVICNSKGQVLWAKRYGQNSWQFPQGGINDNESAEQAMYRELFEEVGLSPKDVKILYISKHWLRYKLP
KRLLRYDSKPVCIGQKQRWFLLQLVSDEKNINMQSSKSPEFDGWRWVSFWYPVRQVVSFKKEVYRKAMKEFASVLFDGAK
ENLLSSKSNESDLKTHHTTKKSTFLTKHSKKHFHKSRG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=156, Percent_Identity=78.2051282051282, Blast_Score=271, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_PASMU (P57809)

Other databases:

- EMBL:   AY442169
- EMBL:   AE004439
- RefSeq:   NP_245019.1
- ProteinModelPortal:   P57809
- SMR:   P57809
- GeneID:   1243429
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0082
- NMPDR:   fig|272843.1.peg.82
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- ProtClustDB:   PRK00714
- BioCyc:   PMUL272843:PM0082-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 23344; Mature: 23344

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFDGYRPNVGIVICNSKGQVLWAKRYGQNSWQFPQGGINDNESAEQAMYRELFEEVGL
CCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
SPKDVKILYISKHWLRYKLPKRLLRYDSKPVCIGQKQRWFLLQLVSDEKNINMQSSKSPE
CCCCEEEEEECHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCC
FDGWRWVSFWYPVRQVVSFKKEVYRKAMKEFASVLFDGAKENLLSSKSNESDLKTHHTTK
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHCCCH
KSTFLTKHSKKHFHKSRG
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDFDGYRPNVGIVICNSKGQVLWAKRYGQNSWQFPQGGINDNESAEQAMYRELFEEVGL
CCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
SPKDVKILYISKHWLRYKLPKRLLRYDSKPVCIGQKQRWFLLQLVSDEKNINMQSSKSPE
CCCCEEEEEECHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCC
FDGWRWVSFWYPVRQVVSFKKEVYRKAMKEFASVLFDGAKENLLSSKSNESDLKTHHTTK
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHCCCH
KSTFLTKHSKKHFHKSRG
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100