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The map label for this gene is nagZ

Identifier: 15601936

GI number: 15601936

Start: 97334

End: 98389

Strand: Reverse

Name: nagZ

Synonym: PM0071

Alternate gene names: 15601936

Gene position: 98389-97334 (Counterclockwise)

Preceding gene: 15601937

Following gene: 161723317

Centisome position: 4.36

GC content: 44.03

Gene sequence:

>1056_bases
ATGTCAACACTATTGATCGATTTACAAGGTCAAGAACTTAGCCAAGAAGAAGTCGAGCTGTTATCACATCCTTTAGTAGC
AGGGCTCATTTTATTTACACGGAATTTCCATGATCGCGCCCAAATGCAAGCGCTGATCCAATCGATTCGTCAACGCGTCA
AGAAGCCGTTGTTGATTACGGTGGATCAAGAAGGTGGGCGAGTTCAGCGTTTTCGTGAAGGTTTCACCCAACTTCCTGCT
ATGCAAGCCTTTGCCTGTTTAATTGATGATCCTGTACAACAAACAAACATGGCACAGCAAGCTGGGTGGCAAATGGCAGC
AGAAATGACCGCACTTGGTATTGATCTCAGCTTTGCGCCTGTTTTAGATTTAGGACATCAATGTCAAGCCATTGGCGACC
GCAGTTTTCATTCACAAGCAGAAATGACACTCAACCTTGCCAGCGCCTTTATTGACGGTATGCATCAAGTGGGAATGGCC
GCCACGGGTAAGCATTTTCCGGGTCATGGTCATGTGATTGCAGATTCACATTTAGAAACGCCTTATGATGAACGTCCAAA
ACAACAGATCTTTGCGCAAGATATTCAGCCATTCCAGCAGTTGATTCAACAAAATATGCTCAATGCCATCATGCCTGCAC
ATGTGATTTATAGCCAATGCGATCCTCAACCTGCGAGTGGTTCTGCATATTGGTTAAAACAGGTACTACGCCAACAACTT
GGCTTTAACGGTGCTATTTTCTCTGATGATCTCGGTATGAAAGGCGCGGGCTTTATGGGGAATTTTGTGCAACGTTGTGA
GCAATCTTTGCAGGCGGGTTGTGATTTACTGTTACTGTGTAATGAAAGAGAAGGCGTTATCCAAGTGTTAGATAATTTAA
AACTTTCTGAAACAGAGCCGCACTTTGCCCTACGTCAACAGCGTTTACAGCAGCTTTTCAAACGTAAAACTATTCGTTGG
TCTGAATTGGAAGCCACTTCACGTTGGTTGGAAAATCGCAAAATATTGACCGCACTTCAACAACGCTGGCTTGATAACAA
AGCCAACAAACATTAA

Upstream 100 bases:

>100_bases
TAGGCTTACAAGGGCATGAAAAATACATTATTCCGTTAAATAAACCCACTGCAGAAAGCCAAAACTACCGTTTATATCTG
CGCTTAAAATAAGGTCTTTT

Downstream 100 bases:

>100_bases
TTAATTATGTCATCTCCTTCTACTTCTTTTGCGTTGCCTTGTCAGCATTATCAACGCGGCGATTGTCGTTCTTGTCAATG
GCTGGCGACGCCTTACTCAA

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSTLLIDLQGQELSQEEVELLSHPLVAGLILFTRNFHDRAQMQALIQSIRQRVKKPLLITVDQEGGRVQRFREGFTQLPA
MQAFACLIDDPVQQTNMAQQAGWQMAAEMTALGIDLSFAPVLDLGHQCQAIGDRSFHSQAEMTLNLASAFIDGMHQVGMA
ATGKHFPGHGHVIADSHLETPYDERPKQQIFAQDIQPFQQLIQQNMLNAIMPAHVIYSQCDPQPASGSAYWLKQVLRQQL
GFNGAIFSDDLGMKGAGFMGNFVQRCEQSLQAGCDLLLLCNEREGVIQVLDNLKLSETEPHFALRQQRLQQLFKRKTIRW
SELEATSRWLENRKILTALQQRWLDNKANKH

Sequences:

>Translated_351_residues
MSTLLIDLQGQELSQEEVELLSHPLVAGLILFTRNFHDRAQMQALIQSIRQRVKKPLLITVDQEGGRVQRFREGFTQLPA
MQAFACLIDDPVQQTNMAQQAGWQMAAEMTALGIDLSFAPVLDLGHQCQAIGDRSFHSQAEMTLNLASAFIDGMHQVGMA
ATGKHFPGHGHVIADSHLETPYDERPKQQIFAQDIQPFQQLIQQNMLNAIMPAHVIYSQCDPQPASGSAYWLKQVLRQQL
GFNGAIFSDDLGMKGAGFMGNFVQRCEQSLQAGCDLLLLCNEREGVIQVLDNLKLSETEPHFALRQQRLQQLFKRKTIRW
SELEATSRWLENRKILTALQQRWLDNKANKH
>Mature_350_residues
STLLIDLQGQELSQEEVELLSHPLVAGLILFTRNFHDRAQMQALIQSIRQRVKKPLLITVDQEGGRVQRFREGFTQLPAM
QAFACLIDDPVQQTNMAQQAGWQMAAEMTALGIDLSFAPVLDLGHQCQAIGDRSFHSQAEMTLNLASAFIDGMHQVGMAA
TGKHFPGHGHVIADSHLETPYDERPKQQIFAQDIQPFQQLIQQNMLNAIMPAHVIYSQCDPQPASGSAYWLKQVLRQQLG
FNGAIFSDDLGMKGAGFMGNFVQRCEQSLQAGCDLLLLCNEREGVIQVLDNLKLSETEPHFALRQQRLQQLFKRKTIRWS
ELEATSRWLENRKILTALQQRWLDNKANKH

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=349, Percent_Identity=53.5816618911175, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_PASMU (Q9CPH0)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245008.1
- ProteinModelPortal:   Q9CPH0
- SMR:   Q9CPH0
- GeneID:   1243418
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0071
- NMPDR:   fig|272843.1.peg.71
- HOGENOM:   HBG617255
- OMA:   DLTMEGA
- ProtClustDB:   PRK05337
- BioCyc:   PMUL272843:PM0071-MONOMER
- BRENDA:   3.2.1.52
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 39668; Mature: 39537

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 249-249

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLLIDLQGQELSQEEVELLSHPLVAGLILFTRNFHDRAQMQALIQSIRQRVKKPLLIT
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEE
VDQEGGRVQRFREGFTQLPAMQAFACLIDDPVQQTNMAQQAGWQMAAEMTALGIDLSFAP
EECCCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VLDLGHQCQAIGDRSFHSQAEMTLNLASAFIDGMHQVGMAATGKHFPGHGHVIADSHLET
HHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCEEECCCCCC
PYDERPKQQIFAQDIQPFQQLIQQNMLNAIMPAHVIYSQCDPQPASGSAYWLKQVLRQQL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
GFNGAIFSDDLGMKGAGFMGNFVQRCEQSLQAGCDLLLLCNEREGVIQVLDNLKLSETEP
CCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCH
HFALRQQRLQQLFKRKTIRWSELEATSRWLENRKILTALQQRWLDNKANKH
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STLLIDLQGQELSQEEVELLSHPLVAGLILFTRNFHDRAQMQALIQSIRQRVKKPLLIT
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEE
VDQEGGRVQRFREGFTQLPAMQAFACLIDDPVQQTNMAQQAGWQMAAEMTALGIDLSFAP
EECCCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VLDLGHQCQAIGDRSFHSQAEMTLNLASAFIDGMHQVGMAATGKHFPGHGHVIADSHLET
HHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCEEECCCCCC
PYDERPKQQIFAQDIQPFQQLIQQNMLNAIMPAHVIYSQCDPQPASGSAYWLKQVLRQQL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
GFNGAIFSDDLGMKGAGFMGNFVQRCEQSLQAGCDLLLLCNEREGVIQVLDNLKLSETEP
CCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCH
HFALRQQRLQQLFKRKTIRWSELEATSRWLENRKILTALQQRWLDNKANKH
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100