Click here to switch to the map view.

The map label for this gene is yfbQ [C]

Identifier: 15601917

GI number: 15601917

Start: 56904

End: 58118

Strand: Reverse

Name: yfbQ [C]

Synonym: PM0052

Alternate gene names: 15601917

Gene position: 58118-56904 (Counterclockwise)

Preceding gene: 15601925

Following gene: 15601916

Centisome position: 2.57

GC content: 42.39

Gene sequence:

>1215_bases
ATGGCGCATTTTCCTAAATCAGATAAATTAGAACACGTTTGTTACGATATTCGCGGACCTGTTCATAAAGAAGCACTTCG
TTTAGAAGAAGAAGGACATAAAATTCTCAAGCTTAATATTGGTAATCCCGCCCCTTTTGGTTTTGAAGCACCAGATGAAA
TCTTAGTTGATGTCATTCGCAACTTACCCACCGCACAAGGCTATTGTGACTCGAAAGGCTTGTATTCTGCACGTAAAGCT
ATTGTGCAATATTACCAATCAAAAGGCATTCACGGGGCGACGGTGAATGATGTGTACATTGGTAATGGGGTGTCTGAATT
AATCACCATGTCATTACAAGCGTTGCTCAATGACGGCGATGAAGTGCTGATTCCGATGCCAGACTATCCGCTTTGGACTG
CCGCGGCGACTTTAGCCGGTGGTAAACCAGTGCACTATTTATGTGATGAAGAAGCGAATTGGTTTCCTGATGTGAATGAT
ATCAAAAGCAAAATCACAAAGCGTACTAAAGCGATTGTGGTAATTAATCCCAATAACCCAACGGGTGCGGTATACAGTCA
AGATTTGCTGTTAGAGATCATTGAAGTGGCGCGCCAACATAAATTGATTATTTTTGCCGACGAGATCTACGATAAAATTT
TATATGATGATGCAGTGCACCACCATATTGCCGCTCTCGCACCAGATATTTTAACCGTCACTTTTAATGGGTTGTCGAAA
GCCTACCGTGTCGCGGGTTTCCGCCAAGGTTGGATGATCTTAAACGGACCGAAAAAAGCCGCTGCGGGTTATATTGAAGG
GCTCGATATGTTGGCGTCTATGCGACTTTGCGCCAATGTACCAATGCAACATGCGATTCAAACTGCGCTAGGTGGCTATC
AAAGTATTAATGAATTTATCCTTCCCGGTGGGCGTTTGCTTGAGCAGCGCAATAAAGCCTATGAGTTAATTAATCAAATC
CCTGGGGTAAGTTGCATCAAACCGCAAGGTGCGATGTATATGTTCCCGAAAATCGACATCAAAAAATTTAATATCTATGA
TGATGAAAAGATGGTGTTTGATTTGTTGGCACAAGAAAAAGTGTTATTAGTACATGGACGTGGTTTCAACTGGCATTCCC
CTGATCATTTCCGGATTGTCACTTTACCTCATGTTCATCAAATTGAAGAGGCGCTCACGAAACTTGCTCGTTTCTTAGCC
CACTATCATCAATAA

Upstream 100 bases:

>100_bases
GAAATTTTTACAAAATCTTTTCTCCCGCCTTAAATAAGCGTAAAGTGTCGTTATTTTATCCAATATCAATCGTTTCCGTT
TACAAGCATAAGGTCTATCT

Downstream 100 bases:

>100_bases
TTCTTGCTACTTACGGCAAACCGTTTCCTTGATGTTTCGGTTTGCCTTTTTATTTTCTGCCTTCTCGACCATTTCACTTT
CCTCGCATTATTACAAGTAA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MAHFPKSDKLEHVCYDIRGPVHKEALRLEEEGHKILKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IVQYYQSKGIHGATVNDVYIGNGVSELITMSLQALLNDGDEVLIPMPDYPLWTAAATLAGGKPVHYLCDEEANWFPDVND
IKSKITKRTKAIVVINPNNPTGAVYSQDLLLEIIEVARQHKLIIFADEIYDKILYDDAVHHHIAALAPDILTVTFNGLSK
AYRVAGFRQGWMILNGPKKAAAGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYELINQI
PGVSCIKPQGAMYMFPKIDIKKFNIYDDEKMVFDLLAQEKVLLVHGRGFNWHSPDHFRIVTLPHVHQIEEALTKLARFLA
HYHQ

Sequences:

>Translated_404_residues
MAHFPKSDKLEHVCYDIRGPVHKEALRLEEEGHKILKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IVQYYQSKGIHGATVNDVYIGNGVSELITMSLQALLNDGDEVLIPMPDYPLWTAAATLAGGKPVHYLCDEEANWFPDVND
IKSKITKRTKAIVVINPNNPTGAVYSQDLLLEIIEVARQHKLIIFADEIYDKILYDDAVHHHIAALAPDILTVTFNGLSK
AYRVAGFRQGWMILNGPKKAAAGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYELINQI
PGVSCIKPQGAMYMFPKIDIKKFNIYDDEKMVFDLLAQEKVLLVHGRGFNWHSPDHFRIVTLPHVHQIEEALTKLARFLA
HYHQ
>Mature_403_residues
AHFPKSDKLEHVCYDIRGPVHKEALRLEEEGHKILKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKAI
VQYYQSKGIHGATVNDVYIGNGVSELITMSLQALLNDGDEVLIPMPDYPLWTAAATLAGGKPVHYLCDEEANWFPDVNDI
KSKITKRTKAIVVINPNNPTGAVYSQDLLLEIIEVARQHKLIIFADEIYDKILYDDAVHHHIAALAPDILTVTFNGLSKA
YRVAGFRQGWMILNGPKKAAAGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYELINQIP
GVSCIKPQGAMYMFPKIDIKKFNIYDDEKMVFDLLAQEKVLLVHGRGFNWHSPDHFRIVTLPHVHQIEEALTKLARFLAH
YHQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=28.1167108753316, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI19263340, Length=463, Percent_Identity=26.5658747300216, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=28.5326086956522, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4885351, Length=469, Percent_Identity=26.226012793177, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI95147551, Length=164, Percent_Identity=32.3170731707317, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI169881279, Length=164, Percent_Identity=32.3170731707317, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI56713254, Length=193, Percent_Identity=29.0155440414508, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI56713256, Length=193, Percent_Identity=29.0155440414508, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI169881281, Length=148, Percent_Identity=31.0810810810811, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI187936925, Length=380, Percent_Identity=23.6842105263158, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI14211921, Length=380, Percent_Identity=23.6842105263158, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI149944424, Length=365, Percent_Identity=21.6438356164384, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=77.2277227722772, Blast_Score=674, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=398, Percent_Identity=24.6231155778894, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786816, Length=243, Percent_Identity=23.4567901234568, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=29.4594594594595, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71981209, Length=467, Percent_Identity=25.4817987152034, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=205, Percent_Identity=31.7073170731707, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=205, Percent_Identity=31.7073170731707, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=202, Percent_Identity=31.6831683168317, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=303, Percent_Identity=26.4026402640264, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=358, Percent_Identity=27.6536312849162, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=346, Percent_Identity=27.4566473988439, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=340, Percent_Identity=23.8235294117647, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=395, Percent_Identity=28.3544303797468, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24641770, Length=466, Percent_Identity=26.3948497854077, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641760, Length=466, Percent_Identity=26.3948497854077, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641768, Length=466, Percent_Identity=26.3948497854077, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641766, Length=466, Percent_Identity=26.3948497854077, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641764, Length=466, Percent_Identity=26.3948497854077, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI45551451, Length=466, Percent_Identity=26.3948497854077, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573069, Length=323, Percent_Identity=25.077399380805, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646114, Length=323, Percent_Identity=25.077399380805, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573067, Length=323, Percent_Identity=25.077399380805, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573065, Length=323, Percent_Identity=25.077399380805, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45286; Mature: 45155

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHFPKSDKLEHVCYDIRGPVHKEALRLEEEGHKILKLNIGNPAPFGFEAPDEILVDVIR
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLYSARKAIVQYYQSKGIHGATVNDVYIGNGVSELITMSLQALLNDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCEEECCCHHHHHHHHHHHHHCCCC
EVLIPMPDYPLWTAAATLAGGKPVHYLCDEEANWFPDVNDIKSKITKRTKAIVVINPNNP
EEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHEEEEEEECCCC
TGAVYSQDLLLEIIEVARQHKLIIFADEIYDKILYDDAVHHHIAALAPDILTVTFNGLSK
CCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHH
AYRVAGFRQGWMILNGPKKAAAGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFI
HHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRNKAYELINQIPGVSCIKPQGAMYMFPKIDIKKFNIYDDEKMVFDLLAQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCEEEEEECCCCHHHHHHHHCCCC
VLLVHGRGFNWHSPDHFRIVTLPHVHQIEEALTKLARFLAHYHQ
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AHFPKSDKLEHVCYDIRGPVHKEALRLEEEGHKILKLNIGNPAPFGFEAPDEILVDVIR
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLYSARKAIVQYYQSKGIHGATVNDVYIGNGVSELITMSLQALLNDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCEEECCCHHHHHHHHHHHHHCCCC
EVLIPMPDYPLWTAAATLAGGKPVHYLCDEEANWFPDVNDIKSKITKRTKAIVVINPNNP
EEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHEEEEEEECCCC
TGAVYSQDLLLEIIEVARQHKLIIFADEIYDKILYDDAVHHHIAALAPDILTVTFNGLSK
CCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHH
AYRVAGFRQGWMILNGPKKAAAGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFI
HHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRNKAYELINQIPGVSCIKPQGAMYMFPKIDIKKFNIYDDEKMVFDLLAQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCEEEEEECCCCHHHHHHHHCCCC
VLLVHGRGFNWHSPDHFRIVTLPHVHQIEEALTKLARFLAHYHQ
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]