BacMap

Definition	Borrelia burgdorferi B31 chromosome, complete genome.
Accession	NC_001318
Length	910,724

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The map label for this gene is ftsH

Identifier: 15595134

GI number: 15595134

Start: 825701

End: 827620

Strand: Direct

Name: ftsH

Synonym: BB0789

Alternate gene names: 15595134

Gene position: 825701-827620 (Clockwise)

Preceding gene: 15595133

Following gene: 15595135

Centisome position: 90.66

GC content: 35.94

Gene sequence:

>1920_bases
ATGAATGGCAATAATAATATGAATAACAATGGAAAATCTAACAACAAAAAAAAGAATAAAAATTGGATTTTAGGACTTGT
TGTTGTTTTTCTAATTTCAGCAATATTTATGTCATATTTTATAAGGGGGGGGGAAAGCTATAAAAATGTTCCTTATAGCA
CTTTTCAGAGTTATTTAGACAATGGTCTAGTTGAGTCTGTAGTAATAATTGATAAAAATTTGATTCAATTTGTCGTCAAG
GGTTCTAACTTTGCAAAGTCTTATTTTTCTACCAGCATTCCCTATCTTGATATAAATTTACTTTCAGAACTAAAAAATAA
AAAAGTTGAGCTTAGCTCAGGGAAAAGTCAAGCTTCTCTGATTGGGGTTTTATTACAAACTTTGCCATGGATTTTGTTTT
TTATTTTCTTTTTCTTTATATTTCGTCAAACTCAAGGTGGCGGTGGGAAGGTTTTTACATTTGGGAAAAGTAATGCTCAA
AAGTATGAAGCTGGAAAGAATAAAATCACCTTTAAAGATGTGGCTGGTCAAGAAGAGGTTAAGCAAGAGCTTCGAGAAGT
TGTCGAATTTCTTAAAAATCCAAAAAAATTTGAAAAAATAGGTGCAAAAATCCCCAAAGGAGTGCTTTTAGTGGGCTCTC
CGGGTACTGGCAAGACTTTGCTTGCCAAAGCCGTTGCCGGTGAGGCTGGGGTTAGTTTCTTTCACATGTCAGGCTCAGAT
TTTGTTGAAATGTTTGTTGGGGTTGGAGCAAGTCGTGTTAGAGATTTATTTGATAATGCTAGAAAAAATTCTCCATGTAT
TATTTTTATTGATGAGCTTGATGCTGTTGGTCGAAGTCGTGGTGCGGGGCTTGGCGGTGGTCATGATGAAAGAGAGCAAA
CTCTTAATCAGCTGTTAGTTGAAATGGATGGATTTGGAACGCATACCAATGTAATTGTTATGGCCGCTACAAATCGTCCC
GATGTTCTTGACTCTGCTTTGCTTAGGCCTGGACGATTTGACAGGCAAGTAACAGTTTCTTTGCCTGATATTAAGGAAAG
AGAGGCAATATTAAATATTCATTCTTTAAAAACGAAGCTTTCAAAAGATATTAATTTACAAGTAATAGCAAGAGCTACTC
CTGGAGCTAGTGGTGCTGATCTTGCAAATTTAATTAATGAAGGAGCCTTAATAGCTGCAAGGAATAATCAAGATGAAATT
TTAATGAAGGATATGGAAGAAGCCAGAGATAAAATATTGATGGGAGTTGCAAAAAAATCCATGACTATTACTGATAGGCA
AAAGCTTGAGACGGCTTATCATGAGGCAGGCCATGCTTTGCTTCACTATTATCTTGAACATGCTGATCCACTTCACAAAG
TTACCATTATTCCAAGGGGCAGGGCACTTGGTGTTGCATTTTCTCTTCCAAGGGAAGATAGACTTTCAATAAACAAACAC
CAAATTCTTGACAAAATAAAGATATGCTATGGTGGTTATGCTAGCGAGCAAATAAATTTGGGTGTTACAACAGCGGGTGT
TCAAAATGATTTAATGCAAGCTACTAGTTTGGCTAAAAAAATGGTTACGGAGTGGGGAATGGGTGAAGAAGTTGGTCCAA
TATTTTTAGTAGACGATGAAGCACCTATTTTCCTTCCGAAAGAGTTTTCAAAGGCTAAAGCTTATTCTGAGAACACTGCC
GATAAAGTTGACAGAGAGGTAAAAAGAATACTTGAAGAATGTTTAAAAGAGGCATCGGATATTCTTTTAAAGCATAAGGA
TCAACTTGTTAAGCTTGCAAAAGAACTTGTTTTAAAAGAAACTTTGACAGACAAAGAAGTGAGAGAGCTTTTGGGTTTTG
AAGCTAATAAGGATGAATACGATTTATTTTCATCAGACTCTACTACAAAAGAAGTAAAGGGGGAGGATGTAAAAGGTTAG

Upstream 100 bases:

>100_bases
TAATTGGGATTATTGATTTAAATACTTTAAACTTAGTATGGAGTGAAAAAAGCATTCTTAAAAAAATTAATATATCTTTG
ATTGGAGGGCTTTTAAAGGA

Downstream 100 bases:

>100_bases
GCAAGTGTTTATGTTTTATTTGAAGATGGGTTTCATTCTTTTTATTTCTATAAACCTATATGCAATTTCAGTCAAAGAAG
ATGAAGATATTTCAAGTATT

Product: cell division protein FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MNGNNNMNNNGKSNNKKKNKNWILGLVVVFLISAIFMSYFIRGGESYKNVPYSTFQSYLDNGLVESVVIIDKNLIQFVVK
GSNFAKSYFSTSIPYLDINLLSELKNKKVELSSGKSQASLIGVLLQTLPWILFFIFFFFIFRQTQGGGGKVFTFGKSNAQ
KYEAGKNKITFKDVAGQEEVKQELREVVEFLKNPKKFEKIGAKIPKGVLLVGSPGTGKTLLAKAVAGEAGVSFFHMSGSD
FVEMFVGVGASRVRDLFDNARKNSPCIIFIDELDAVGRSRGAGLGGGHDEREQTLNQLLVEMDGFGTHTNVIVMAATNRP
DVLDSALLRPGRFDRQVTVSLPDIKEREAILNIHSLKTKLSKDINLQVIARATPGASGADLANLINEGALIAARNNQDEI
LMKDMEEARDKILMGVAKKSMTITDRQKLETAYHEAGHALLHYYLEHADPLHKVTIIPRGRALGVAFSLPREDRLSINKH
QILDKIKICYGGYASEQINLGVTTAGVQNDLMQATSLAKKMVTEWGMGEEVGPIFLVDDEAPIFLPKEFSKAKAYSENTA
DKVDREVKRILEECLKEASDILLKHKDQLVKLAKELVLKETLTDKEVRELLGFEANKDEYDLFSSDSTTKEVKGEDVKG

Sequences:

>Translated_639_residues
MNGNNNMNNNGKSNNKKKNKNWILGLVVVFLISAIFMSYFIRGGESYKNVPYSTFQSYLDNGLVESVVIIDKNLIQFVVK
GSNFAKSYFSTSIPYLDINLLSELKNKKVELSSGKSQASLIGVLLQTLPWILFFIFFFFIFRQTQGGGGKVFTFGKSNAQ
KYEAGKNKITFKDVAGQEEVKQELREVVEFLKNPKKFEKIGAKIPKGVLLVGSPGTGKTLLAKAVAGEAGVSFFHMSGSD
FVEMFVGVGASRVRDLFDNARKNSPCIIFIDELDAVGRSRGAGLGGGHDEREQTLNQLLVEMDGFGTHTNVIVMAATNRP
DVLDSALLRPGRFDRQVTVSLPDIKEREAILNIHSLKTKLSKDINLQVIARATPGASGADLANLINEGALIAARNNQDEI
LMKDMEEARDKILMGVAKKSMTITDRQKLETAYHEAGHALLHYYLEHADPLHKVTIIPRGRALGVAFSLPREDRLSINKH
QILDKIKICYGGYASEQINLGVTTAGVQNDLMQATSLAKKMVTEWGMGEEVGPIFLVDDEAPIFLPKEFSKAKAYSENTA
DKVDREVKRILEECLKEASDILLKHKDQLVKLAKELVLKETLTDKEVRELLGFEANKDEYDLFSSDSTTKEVKGEDVKG
>Mature_639_residues
MNGNNNMNNNGKSNNKKKNKNWILGLVVVFLISAIFMSYFIRGGESYKNVPYSTFQSYLDNGLVESVVIIDKNLIQFVVK
GSNFAKSYFSTSIPYLDINLLSELKNKKVELSSGKSQASLIGVLLQTLPWILFFIFFFFIFRQTQGGGGKVFTFGKSNAQ
KYEAGKNKITFKDVAGQEEVKQELREVVEFLKNPKKFEKIGAKIPKGVLLVGSPGTGKTLLAKAVAGEAGVSFFHMSGSD
FVEMFVGVGASRVRDLFDNARKNSPCIIFIDELDAVGRSRGAGLGGGHDEREQTLNQLLVEMDGFGTHTNVIVMAATNRP
DVLDSALLRPGRFDRQVTVSLPDIKEREAILNIHSLKTKLSKDINLQVIARATPGASGADLANLINEGALIAARNNQDEI
LMKDMEEARDKILMGVAKKSMTITDRQKLETAYHEAGHALLHYYLEHADPLHKVTIIPRGRALGVAFSLPREDRLSINKH
QILDKIKICYGGYASEQINLGVTTAGVQNDLMQATSLAKKMVTEWGMGEEVGPIFLVDDEAPIFLPKEFSKAKAYSENTA
DKVDREVKRILEECLKEASDILLKHKDQLVKLAKELVLKETLTDKEVRELLGFEANKDEYDLFSSDSTTKEVKGEDVKG

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=624, Percent_Identity=43.2692307692308, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI21327685, Length=445, Percent_Identity=46.7415730337079, Blast_Score=398, Evalue=1e-110,
Organism=Homo sapiens, GI7657689, Length=445, Percent_Identity=46.7415730337079, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI4507173, Length=449, Percent_Identity=44.097995545657, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI24497435, Length=255, Percent_Identity=44.7058823529412, Blast_Score=219, Evalue=7e-57,
Organism=Homo sapiens, GI4506209, Length=258, Percent_Identity=42.6356589147287, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=43.3628318584071, Blast_Score=204, Evalue=3e-52,
Organism=Homo sapiens, GI195539395, Length=245, Percent_Identity=41.2244897959184, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI24430151, Length=245, Percent_Identity=40, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI89064750, Length=249, Percent_Identity=40.5622489959839, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI5729991, Length=249, Percent_Identity=40.5622489959839, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI21361144, Length=238, Percent_Identity=43.2773109243698, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI24430155, Length=249, Percent_Identity=40.5622489959839, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI45643123, Length=275, Percent_Identity=38.1818181818182, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI45643125, Length=275, Percent_Identity=38.1818181818182, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI157671927, Length=237, Percent_Identity=40.5063291139241, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI40806173, Length=137, Percent_Identity=59.8540145985402, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI229577436, Length=249, Percent_Identity=38.5542168674699, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI4505725, Length=226, Percent_Identity=38.0530973451327, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI194018488, Length=263, Percent_Identity=38.7832699619772, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI153792536, Length=240, Percent_Identity=39.5833333333333, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI14149767, Length=292, Percent_Identity=36.3013698630137, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI62177112, Length=292, Percent_Identity=36.3013698630137, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI24497618, Length=239, Percent_Identity=38.0753138075314, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI5901990, Length=235, Percent_Identity=40.8510638297872, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI226371754, Length=235, Percent_Identity=37.4468085106383, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI11875211, Length=271, Percent_Identity=37.6383763837638, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI40806170, Length=271, Percent_Identity=37.6383763837638, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI7019569, Length=238, Percent_Identity=37.8151260504202, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI17865802, Length=235, Percent_Identity=37.8723404255319, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI31377644, Length=232, Percent_Identity=37.0689655172414, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI31742536, Length=233, Percent_Identity=34.3347639484979, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI112789543, Length=233, Percent_Identity=34.3347639484979, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI310125280, Length=211, Percent_Identity=38.8625592417062, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI156564401, Length=211, Percent_Identity=38.8625592417062, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI310125282, Length=237, Percent_Identity=37.9746835443038, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI64084766, Length=270, Percent_Identity=27.037037037037, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI116292174, Length=252, Percent_Identity=29.7619047619048, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI75677353, Length=196, Percent_Identity=33.6734693877551, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI283436222, Length=218, Percent_Identity=30.2752293577982, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI283436224, Length=218, Percent_Identity=30.2752293577982, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI283436220, Length=218, Percent_Identity=30.2752293577982, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789568, Length=598, Percent_Identity=50.1672240802676, Blast_Score=573, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71994521, Length=645, Percent_Identity=42.4806201550388, Blast_Score=439, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17554264, Length=466, Percent_Identity=44.6351931330472, Blast_Score=370, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI115534323, Length=454, Percent_Identity=45.5947136563877, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17554786, Length=255, Percent_Identity=44.7058823529412, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI25144281, Length=255, Percent_Identity=44.7058823529412, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI25144278, Length=255, Percent_Identity=44.7058823529412, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17563248, Length=258, Percent_Identity=43.0232558139535, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=41.6326530612245, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI17532375, Length=249, Percent_Identity=39.3574297188755, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71987364, Length=258, Percent_Identity=41.8604651162791, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71987372, Length=258, Percent_Identity=41.8604651162791, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17508701, Length=254, Percent_Identity=41.7322834645669, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17505546, Length=260, Percent_Identity=40, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17531535, Length=229, Percent_Identity=42.7947598253275, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17554784, Length=244, Percent_Identity=42.6229508196721, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=237, Percent_Identity=41.3502109704641, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17537217, Length=298, Percent_Identity=36.9127516778523, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI193206114, Length=244, Percent_Identity=41.3934426229508, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI133931034, Length=244, Percent_Identity=41.3934426229508, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=244, Percent_Identity=41.3934426229508, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25153574, Length=247, Percent_Identity=38.0566801619433, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=47.8787878787879, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=47.8787878787879, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI193209502, Length=226, Percent_Identity=38.4955752212389, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17562804, Length=231, Percent_Identity=37.6623376623377, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17560432, Length=263, Percent_Identity=37.2623574144487, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI86561515, Length=238, Percent_Identity=35.7142857142857, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25146157, Length=251, Percent_Identity=38.2470119521912, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI133901662, Length=209, Percent_Identity=37.3205741626794, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI133901658, Length=209, Percent_Identity=37.3205741626794, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32563584, Length=231, Percent_Identity=38.961038961039, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17508421, Length=231, Percent_Identity=38.961038961039, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541226, Length=231, Percent_Identity=35.4978354978355, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541224, Length=231, Percent_Identity=35.4978354978355, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71990294, Length=199, Percent_Identity=31.6582914572864, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323736, Length=605, Percent_Identity=40.9917355371901, Blast_Score=447, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6320854, Length=631, Percent_Identity=40.5705229793978, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6325281, Length=501, Percent_Identity=43.5129740518962, Blast_Score=413, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6322704, Length=258, Percent_Identity=43.7984496124031, Blast_Score=217, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=42.8571428571429, Blast_Score=209, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6320077, Length=229, Percent_Identity=44.9781659388646, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6324833, Length=256, Percent_Identity=42.578125, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=39.5918367346939, Blast_Score=200, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6320602, Length=248, Percent_Identity=44.3548387096774, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6324691, Length=256, Percent_Identity=42.1875, Blast_Score=194, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6322994, Length=267, Percent_Identity=36.3295880149813, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323429, Length=259, Percent_Identity=36.2934362934363, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324000, Length=229, Percent_Identity=40.174672489083, Blast_Score=160, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6322651, Length=235, Percent_Identity=39.1489361702128, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321709, Length=265, Percent_Identity=36.6037735849057, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6325431, Length=252, Percent_Identity=37.6984126984127, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6321465, Length=229, Percent_Identity=37.5545851528384, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6325183, Length=258, Percent_Identity=34.4961240310078, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=37.962962962963, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=271, Percent_Identity=32.4723247232472, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320583, Length=201, Percent_Identity=29.3532338308458, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574878, Length=644, Percent_Identity=42.5465838509317, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24665814, Length=644, Percent_Identity=42.5465838509317, Blast_Score=458, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24658770, Length=489, Percent_Identity=46.2167689161554, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24639391, Length=465, Percent_Identity=44.9462365591398, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI17137560, Length=243, Percent_Identity=41.9753086419753, Blast_Score=215, Evalue=6e-56,
Organism=Drosophila melanogaster, GI161076488, Length=243, Percent_Identity=41.9753086419753, Blast_Score=215, Evalue=7e-56,
Organism=Drosophila melanogaster, GI161076486, Length=243, Percent_Identity=41.9753086419753, Blast_Score=215, Evalue=7e-56,
Organism=Drosophila melanogaster, GI24651451, Length=255, Percent_Identity=44.3137254901961, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19920408, Length=255, Percent_Identity=43.5294117647059, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI17137738, Length=258, Percent_Identity=43.0232558139535, Blast_Score=212, Evalue=6e-55,
Organism=Drosophila melanogaster, GI45554047, Length=169, Percent_Identity=55.6213017751479, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=40.8163265306122, Blast_Score=198, Evalue=8e-51,
Organism=Drosophila melanogaster, GI18860063, Length=242, Percent_Identity=42.1487603305785, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=41.2244897959184, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI281361487, Length=242, Percent_Identity=42.1487603305785, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI281365776, Length=276, Percent_Identity=38.0434782608696, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24660075, Length=276, Percent_Identity=38.0434782608696, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI45552965, Length=276, Percent_Identity=38.0434782608696, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24652279, Length=206, Percent_Identity=42.2330097087379, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI17738151, Length=239, Percent_Identity=41.4225941422594, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24663015, Length=245, Percent_Identity=39.5918367346939, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24656820, Length=262, Percent_Identity=39.6946564885496, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24656825, Length=262, Percent_Identity=39.6946564885496, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19921202, Length=245, Percent_Identity=38.3673469387755, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281363136, Length=239, Percent_Identity=38.0753138075314, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI78707192, Length=239, Percent_Identity=38.0753138075314, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI20129529, Length=266, Percent_Identity=35.3383458646617, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24644145, Length=233, Percent_Identity=38.1974248927039, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859657, Length=238, Percent_Identity=38.2352941176471, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281360144, Length=293, Percent_Identity=34.4709897610922, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360140, Length=293, Percent_Identity=34.4709897610922, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360136, Length=293, Percent_Identity=34.4709897610922, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24644411, Length=293, Percent_Identity=34.4709897610922, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360142, Length=293, Percent_Identity=34.4709897610922, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI21357333, Length=293, Percent_Identity=34.4709897610922, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360146, Length=293, Percent_Identity=34.4709897610922, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360138, Length=293, Percent_Identity=34.4709897610922, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571849, Length=252, Percent_Identity=39.2857142857143, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28571847, Length=252, Percent_Identity=39.2857142857143, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI20129423, Length=236, Percent_Identity=35.5932203389831, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI21355121, Length=236, Percent_Identity=33.8983050847458, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24581396, Length=289, Percent_Identity=34.9480968858132, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17864540, Length=211, Percent_Identity=38.8625592417062, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573010, Length=211, Percent_Identity=38.3886255924171, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24639486, Length=191, Percent_Identity=35.0785340314136, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_BORBZ (B7J0N5)

Other databases:

- EMBL:   CP001205
- RefSeq:   YP_002375288.1
- ProteinModelPortal:   B7J0N5
- EnsemblBacteria:   EBBORT00000003112
- GeneID:   7106431
- GenomeReviews:   CP001205_GR
- KEGG:   bbz:BbuZS7_0819
- GeneTree:   EBGT00050000007011
- HOGENOM:   HBG724153
- OMA:   ISVAYIQ
- ProtClustDB:   CLSK507838
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 70803; Mature: 70803

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 435-435

Signals:

None

Transmembrane regions:

HASH(0xce447d8)-; HASH(0xd71ef80)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGNNNMNNNGKSNNKKKNKNWILGLVVVFLISAIFMSYFIRGGESYKNVPYSTFQSYLD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHC
NGLVESVVIIDKNLIQFVVKGSNFAKSYFSTSIPYLDINLLSELKNKKVELSSGKSQASL
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEHHHHHHHHCCCEEECCCCHHHHH
IGVLLQTLPWILFFIFFFFIFRQTQGGGGKVFTFGKSNAQKYEAGKNKITFKDVAGQEEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHCCCCCEEEHHCCCHHHH
KQELREVVEFLKNPKKFEKIGAKIPKGVLLVGSPGTGKTLLAKAVAGEAGVSFFHMSGSD
HHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCHH
FVEMFVGVGASRVRDLFDNARKNSPCIIFIDELDAVGRSRGAGLGGGHDEREQTLNQLLV
HHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHH
EMDGFGTHTNVIVMAATNRPDVLDSALLRPGRFDRQVTVSLPDIKEREAILNIHSLKTKL
HHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
SKDINLQVIARATPGASGADLANLINEGALIAARNNQDEILMKDMEEARDKILMGVAKKS
CCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
MTITDRQKLETAYHEAGHALLHYYLEHADPLHKVTIIPRGRALGVAFSLPREDRLSINKH
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCHHCCCCHHH
QILDKIKICYGGYASEQINLGVTTAGVQNDLMQATSLAKKMVTEWGMGEEVGPIFLVDDE
HHHHHHHHHHCCCCCCEEEECEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
APIFLPKEFSKAKAYSENTADKVDREVKRILEECLKEASDILLKHKDQLVKLAKELVLKE
CCEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLTDKEVRELLGFEANKDEYDLFSSDSTTKEVKGEDVKG
HCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCH
>Mature Secondary Structure
MNGNNNMNNNGKSNNKKKNKNWILGLVVVFLISAIFMSYFIRGGESYKNVPYSTFQSYLD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHC
NGLVESVVIIDKNLIQFVVKGSNFAKSYFSTSIPYLDINLLSELKNKKVELSSGKSQASL
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEHHHHHHHHCCCEEECCCCHHHHH
IGVLLQTLPWILFFIFFFFIFRQTQGGGGKVFTFGKSNAQKYEAGKNKITFKDVAGQEEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHCCCCCEEEHHCCCHHHH
KQELREVVEFLKNPKKFEKIGAKIPKGVLLVGSPGTGKTLLAKAVAGEAGVSFFHMSGSD
HHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCHH
FVEMFVGVGASRVRDLFDNARKNSPCIIFIDELDAVGRSRGAGLGGGHDEREQTLNQLLV
HHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHH
EMDGFGTHTNVIVMAATNRPDVLDSALLRPGRFDRQVTVSLPDIKEREAILNIHSLKTKL
HHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
SKDINLQVIARATPGASGADLANLINEGALIAARNNQDEILMKDMEEARDKILMGVAKKS
CCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
MTITDRQKLETAYHEAGHALLHYYLEHADPLHKVTIIPRGRALGVAFSLPREDRLSINKH
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCHHCCCCHHH
QILDKIKICYGGYASEQINLGVTTAGVQNDLMQATSLAKKMVTEWGMGEEVGPIFLVDDE
HHHHHHHHHHCCCCCCEEEECEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
APIFLPKEFSKAKAYSENTADKVDREVKRILEECLKEASDILLKHKDQLVKLAKELVLKE
CCEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLTDKEVRELLGFEANKDEYDLFSSDSTTKEVKGEDVKG
HCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA