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The map label for this gene is mprA [H]

Identifier: 15594915

GI number: 15594915

Start: 583458

End: 583832

Strand: Direct

Name: mprA [H]

Synonym: BB0570

Alternate gene names: 15594915

Gene position: 583458-583832 (Clockwise)

Preceding gene: 15594914

Following gene: 15594917

Centisome position: 64.07

GC content: 36.27

Gene sequence:

>375_bases
ATGAAAAAAAGAATTTTGGTTATTGATGACAATAGGGCAATAAGGCAAAGCGTTGCTTATATTTTAGAACAAAACGGTTT
TGGAGTCTCAGAAGCAAAAGATGGTTTAGAAGGGGTTTTAAGGTTTAAAGAAGCAGTTGGGCAAGGAGATAAAGATTTTG
ACCTTGTTATTACAGATATCAACATGCCTAATTTAGACGGCATTGGGGTTATTAAGCAGATAAGAGAATTTGGCAGCTTT
GTTCCTATACTTGTTCTTACCACTGAATCTGAGCAATCTAAGGTTGATGAGGGTCGTAAAGCGGGCGCTACTGGTTGGCT
TGTTAAACCTTTTAATCCTGAAGCTTTAATGAAGACAATCTCAAAGATATTTTAA

Upstream 100 bases:

>100_bases
TTGATAGAGGAAGCCGAGGATGTTCATTCCTTTGATGAGGGTAGTGTAATTTTGTTTTAATTTTTATATACTTTTTAGGA
GGGTTTTAGGAGAAAATTAG

Downstream 100 bases:

>100_bases
GTTTATATTTGCAATTAATTTGTAGACTTTAAAGTTTTATTATAATTAAAATGATTTTCAATATGTTATTTTAGAATAAG
GACAACCTATTGAAAGAGGT

Product: chemotaxis protein CheY

Products: NA

Alternate protein names: Mycobacterial persistence regulator A [H]

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MKKRILVIDDNRAIRQSVAYILEQNGFGVSEAKDGLEGVLRFKEAVGQGDKDFDLVITDINMPNLDGIGVIKQIREFGSF
VPILVLTTESEQSKVDEGRKAGATGWLVKPFNPEALMKTISKIF

Sequences:

>Translated_124_residues
MKKRILVIDDNRAIRQSVAYILEQNGFGVSEAKDGLEGVLRFKEAVGQGDKDFDLVITDINMPNLDGIGVIKQIREFGSF
VPILVLTTESEQSKVDEGRKAGATGWLVKPFNPEALMKTISKIF
>Mature_124_residues
MKKRILVIDDNRAIRQSVAYILEQNGFGVSEAKDGLEGVLRFKEAVGQGDKDFDLVITDINMPNLDGIGVIKQIREFGSF
VPILVLTTESEQSKVDEGRKAGATGWLVKPFNPEALMKTISKIF

Specific function: Member of the two-component regulatory system mprB/mprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a tr

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788191, Length=124, Percent_Identity=37.9032258064516, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1786599, Length=127, Percent_Identity=33.0708661417323, Blast_Score=73, Evalue=5e-15,
Organism=Escherichia coli, GI1788713, Length=122, Percent_Identity=31.1475409836066, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=31.3559322033898, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1787375, Length=122, Percent_Identity=32.7868852459016, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1786911, Length=107, Percent_Identity=37.3831775700935, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=29.2035398230088, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1789402, Length=122, Percent_Identity=33.6065573770492, Blast_Score=60, Evalue=4e-11,
Organism=Escherichia coli, GI1790863, Length=113, Percent_Identity=31.858407079646, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13726; Mature: 13726

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRILVIDDNRAIRQSVAYILEQNGFGVSEAKDGLEGVLRFKEAVGQGDKDFDLVITDI
CCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
NMPNLDGIGVIKQIREFGSFVPILVLTTESEQSKVDEGRKAGATGWLVKPFNPEALMKTI
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCCCEECCCCHHHHHHHH
SKIF
HHHC
>Mature Secondary Structure
MKKRILVIDDNRAIRQSVAYILEQNGFGVSEAKDGLEGVLRFKEAVGQGDKDFDLVITDI
CCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
NMPNLDGIGVIKQIREFGSFVPILVLTTESEQSKVDEGRKAGATGWLVKPFNPEALMKTI
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCCCEECCCCHHHHHHHH
SKIF
HHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA