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The map label for this gene is ppaX [H]

Identifier: 154248680

GI number: 154248680

Start: 5287940

End: 5288668

Strand: Reverse

Name: ppaX [H]

Synonym: Xaut_4762

Alternate gene names: 154248680

Gene position: 5288668-5287940 (Counterclockwise)

Preceding gene: 154248681

Following gene: 154248679

Centisome position: 99.62

GC content: 70.64

Gene sequence:

>729_bases
ATGACCCCACCCGAGAGCGACGCCGAGCCCGCCCCCGATGCCGCGCCCCTGAAGCTGGTGCTGTTCGATTGCGACGGCAC
GCTGGTGGACAGCCAGCACATGATCGTCGCCGCCATGCGCGACGCCCATGCGGCCCACGGCGTGCCGCTGCCGGGACGGG
ACCGGTTGCTCTCGGTGGTGGGGCTTTCCCTGCCGGAGGCCTTTGCCATGCTCTCGCAGGGTGACCTCGCCTATCCCATC
GAGGCGCTGGTGGACGCTTATCGCAATGCCTTCACCCGGCTACGCAATGCCGAGCCGCCCGAGCCCATGTTCGACGGCGC
CTGGGAGGTGCTGGACACCCTGCGCCGGCGCGACGACGTGGTGCTGGGCATGGTCACCGGCAAGGCGCGGCGCGGGGTGG
ACCGGGTGCTCAAGGCCCATGACATGGAAGGCTGGTTCGCCACCATCCAGACCGCCGACGACGCCCCCTCCAAGCCCCAT
CCGGCCATGGTGTTCCAGGCCATGAAGGAGATCGGCGCGCGCCCGGAGGAGACGGTGGTGGTCGGCGACACCACCTATGA
CGTCTCCATGGCGCTGCAGGCGGGGGCCTCCGCCCTCGGCGTCGGCTGGGGCTATCACGAGGTGGCGGCGCTGGAGCGGG
CCGGGGCGGACCATATCGTCCACCGGTTCGACGAGGTGCCCGCCGCCATCTTCGATCTTCTGGCGCGCCGTCGCGCCATC
GCCGGATAG

Upstream 100 bases:

>100_bases
CCAAGCAGTGCGAGCAGCGGGGCTTCCGCCAGGTCCTGTTCGTGGACCCGTCGGACATCACATGGGTATATGATGTGGCG
ACCCAGCAGATGACCCAGAA

Downstream 100 bases:

>100_bases
GAGGCGGATCATGGGTGATCCCTCAGGGGCCGATCCCGCCGGCCCCCAGACCATGCGCGATTTCCTGGAGGGCATCGAGG
AGCCGGTGGCGGGGGACGAT

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTPPESDAEPAPDAAPLKLVLFDCDGTLVDSQHMIVAAMRDAHAAHGVPLPGRDRLLSVVGLSLPEAFAMLSQGDLAYPI
EALVDAYRNAFTRLRNAEPPEPMFDGAWEVLDTLRRRDDVVLGMVTGKARRGVDRVLKAHDMEGWFATIQTADDAPSKPH
PAMVFQAMKEIGARPEETVVVGDTTYDVSMALQAGASALGVGWGYHEVAALERAGADHIVHRFDEVPAAIFDLLARRRAI
AG

Sequences:

>Translated_242_residues
MTPPESDAEPAPDAAPLKLVLFDCDGTLVDSQHMIVAAMRDAHAAHGVPLPGRDRLLSVVGLSLPEAFAMLSQGDLAYPI
EALVDAYRNAFTRLRNAEPPEPMFDGAWEVLDTLRRRDDVVLGMVTGKARRGVDRVLKAHDMEGWFATIQTADDAPSKPH
PAMVFQAMKEIGARPEETVVVGDTTYDVSMALQAGASALGVGWGYHEVAALERAGADHIVHRFDEVPAAIFDLLARRRAI
AG
>Mature_241_residues
TPPESDAEPAPDAAPLKLVLFDCDGTLVDSQHMIVAAMRDAHAAHGVPLPGRDRLLSVVGLSLPEAFAMLSQGDLAYPIE
ALVDAYRNAFTRLRNAEPPEPMFDGAWEVLDTLRRRDDVVLGMVTGKARRGVDRVLKAHDMEGWFATIQTADDAPSKPHP
AMVFQAMKEIGARPEETVVVGDTTYDVSMALQAGASALGVGWGYHEVAALERAGADHIVHRFDEVPAAIFDLLARRRAIA
G

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=234, Percent_Identity=27.3504273504274, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 26129; Mature: 25998

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPESDAEPAPDAAPLKLVLFDCDGTLVDSQHMIVAAMRDAHAAHGVPLPGRDRLLSVV
CCCCCCCCCCCCCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GLSLPEAFAMLSQGDLAYPIEALVDAYRNAFTRLRNAEPPEPMFDGAWEVLDTLRRRDDV
HCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCE
VLGMVTGKARRGVDRVLKAHDMEGWFATIQTADDAPSKPHPAMVFQAMKEIGARPEETVV
EEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEE
VGDTTYDVSMALQAGASALGVGWGYHEVAALERAGADHIVHRFDEVPAAIFDLLARRRAI
ECCCCHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
AG
CC
>Mature Secondary Structure 
TPPESDAEPAPDAAPLKLVLFDCDGTLVDSQHMIVAAMRDAHAAHGVPLPGRDRLLSVV
CCCCCCCCCCCCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GLSLPEAFAMLSQGDLAYPIEALVDAYRNAFTRLRNAEPPEPMFDGAWEVLDTLRRRDDV
HCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCE
VLGMVTGKARRGVDRVLKAHDMEGWFATIQTADDAPSKPHPAMVFQAMKEIGARPEETVV
EEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEE
VGDTTYDVSMALQAGASALGVGWGYHEVAALERAGADHIVHRFDEVPAAIFDLLARRRAI
ECCCCHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA