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The map label for this gene is lolC [H]

Identifier: 154248147

GI number: 154248147

Start: 4686758

End: 4687984

Strand: Direct

Name: lolC [H]

Synonym: Xaut_4227

Alternate gene names: 154248147

Gene position: 4686758-4687984 (Clockwise)

Preceding gene: 154248146

Following gene: 154248148

Centisome position: 88.28

GC content: 69.03

Gene sequence:

>1227_bases
ATGAACCGCTGGCTGCCGTTCGAATGGATCGCCGCCCTGCGCTTCCTCGGCGAAGGGCGCATGCAGACCGCCTTCATCCT
CGGCGGCATCACCATCGGCGTGGGCGTGATCGTGTTCATGTCGGCCATGCTGGCCGGGCTCCAGACCAATTTCATCAAGC
GGGTGCTGACCTCCCAGCCGCAGATCCAGCTGCTGCCGCCGGAGGAGGTGGCGCGTCCGCTGCGCTTCGATCCGGGCGTG
ATCGAGGGCGCGCTGGTGCAGAAGCCGTCCCAGCGCATTCTCTCCATCGACCAGTGGCAGTCCATCGCTGTCGCCATGCG
GGCGCGGCCTGACGTGGTGGTGGTGGCACCCACGGCGTCGGGATCGGCCCTCGCGGTGCGGGGCGACGCCAGCCGCTCCA
TCTCCATCACCGGCATGGAGCCGGAGCAGTATTTCCGCATCGTGCGGGTGCCCGACTATCTGGTGGCGGGGGAGGCGCGC
CTCGGCACCGATGACATTCTCGTCGGCACCGAGCTGGCGAAGGACCTGGGCGCTGGCGTGGGCGACAAGCTCAACGTGAC
CACGGCTAACGGGAGCGGGCGCATCCTCACCATCACCGGCATCTTCGATTTCGGCAACAAGGCGGCCAACGGGCGCAACA
CCTATGTGGCCCTGCGCACCGCCCAGAGCCTGCTCAACCTCATCGGCGGCGTCACCACCATCGACATGACGGTGACCGAC
ACCTACGCCGCCGAGGACATCGCCCGCGACATCGCCGCCGTGGTGCCGGTGGAGGCGGACAGCTGGATCACCACCAACGC
CCAGTTCTTCACCGCGGTGCGGGCGCAGCAGACCTCCAACACCCTGATCCGGCTGTTCGTGGGCATCTCGGTGGCGTTCG
GCATCGCCGCCGTGCTGGTGGTATCGGTGATCCAGCGCTCCAAGGACATCGGCATCCTGCGCGCCATGGGCGCGTCCCGC
GGGCGGATCCTGCGGGTCTTCCTCATCCAGGGTGGAGTGCTGGGCCTCTTCGGCTCTCTGCTGGGGTCGGCGGCCGGCGC
CGGAGCGCTCATCCTCTGGCACCACCTGCTGCGGCAGGTGGACGGCTCGGAGCTGTTCCCGCTGATCCTGGAGCCGAGCC
TGTTCGTGGCCGCAGCGCTGCTCGCCACCCTGACCGGCGTGGTCGCCGGCCTTGCCCCGGCGGTGCGCGCCGCCAGCATC
GATCCGGTGGAGGCGATCCGTGGCTGA

Upstream 100 bases:

>100_bases
GCGACCAGGTTCAGGTGCTGGAGGGGCTCACCCCCGGCGAGGCGGTGCTGCCGGTGGCCTCGGGGGTGCGCGCCGGCCAG
CGCATCCGGCCGGTGTCGCG

Downstream 100 bases:

>100_bases
TGTGCTGGCGCTTCAGGCGATCCGCAAATCCTACGCCATCGGCACGCCGGTGGAGACCGAGGTGCTGCACGGCATCGACC
TCACCCTGCGGGCCGGCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MNRWLPFEWIAALRFLGEGRMQTAFILGGITIGVGVIVFMSAMLAGLQTNFIKRVLTSQPQIQLLPPEEVARPLRFDPGV
IEGALVQKPSQRILSIDQWQSIAVAMRARPDVVVVAPTASGSALAVRGDASRSISITGMEPEQYFRIVRVPDYLVAGEAR
LGTDDILVGTELAKDLGAGVGDKLNVTTANGSGRILTITGIFDFGNKAANGRNTYVALRTAQSLLNLIGGVTTIDMTVTD
TYAAEDIARDIAAVVPVEADSWITTNAQFFTAVRAQQTSNTLIRLFVGISVAFGIAAVLVVSVIQRSKDIGILRAMGASR
GRILRVFLIQGGVLGLFGSLLGSAAGAGALILWHHLLRQVDGSELFPLILEPSLFVAAALLATLTGVVAGLAPAVRAASI
DPVEAIRG

Sequences:

>Translated_408_residues
MNRWLPFEWIAALRFLGEGRMQTAFILGGITIGVGVIVFMSAMLAGLQTNFIKRVLTSQPQIQLLPPEEVARPLRFDPGV
IEGALVQKPSQRILSIDQWQSIAVAMRARPDVVVVAPTASGSALAVRGDASRSISITGMEPEQYFRIVRVPDYLVAGEAR
LGTDDILVGTELAKDLGAGVGDKLNVTTANGSGRILTITGIFDFGNKAANGRNTYVALRTAQSLLNLIGGVTTIDMTVTD
TYAAEDIARDIAAVVPVEADSWITTNAQFFTAVRAQQTSNTLIRLFVGISVAFGIAAVLVVSVIQRSKDIGILRAMGASR
GRILRVFLIQGGVLGLFGSLLGSAAGAGALILWHHLLRQVDGSELFPLILEPSLFVAAALLATLTGVVAGLAPAVRAASI
DPVEAIRG
>Mature_408_residues
MNRWLPFEWIAALRFLGEGRMQTAFILGGITIGVGVIVFMSAMLAGLQTNFIKRVLTSQPQIQLLPPEEVARPLRFDPGV
IEGALVQKPSQRILSIDQWQSIAVAMRARPDVVVVAPTASGSALAVRGDASRSISITGMEPEQYFRIVRVPDYLVAGEAR
LGTDDILVGTELAKDLGAGVGDKLNVTTANGSGRILTITGIFDFGNKAANGRNTYVALRTAQSLLNLIGGVTTIDMTVTD
TYAAEDIARDIAAVVPVEADSWITTNAQFFTAVRAQQTSNTLIRLFVGISVAFGIAAVLVVSVIQRSKDIGILRAMGASR
GRILRVFLIQGGVLGLFGSLLGSAAGAGALILWHHLLRQVDGSELFPLILEPSLFVAAALLATLTGVVAGLAPAVRAASI
DPVEAIRG

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=408, Percent_Identity=25, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787360, Length=314, Percent_Identity=24.8407643312102, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43121; Mature: 43121

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRWLPFEWIAALRFLGEGRMQTAFILGGITIGVGVIVFMSAMLAGLQTNFIKRVLTSQP
CCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QIQLLPPEEVARPLRFDPGVIEGALVQKPSQRILSIDQWQSIAVAMRARPDVVVVAPTAS
CEEEECHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GSALAVRGDASRSISITGMEPEQYFRIVRVPDYLVAGEARLGTDDILVGTELAKDLGAGV
CCEEEEECCCCCEEEEECCCHHHHEEEEECCCEEEECCCCCCCCCEEEHHHHHHHHCCCC
GDKLNVTTANGSGRILTITGIFDFGNKAANGRNTYVALRTAQSLLNLIGGVTTIDMTVTD
CCCEEEEEECCCCEEEEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEC
TYAAEDIARDIAAVVPVEADSWITTNAQFFTAVRAQQTSNTLIRLFVGISVAFGIAAVLV
HHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVIQRSKDIGILRAMGASRGRILRVFLIQGGVLGLFGSLLGSAAGAGALILWHHLLRQV
HHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHC
DGSELFPLILEPSLFVAAALLATLTGVVAGLAPAVRAASIDPVEAIRG
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MNRWLPFEWIAALRFLGEGRMQTAFILGGITIGVGVIVFMSAMLAGLQTNFIKRVLTSQP
CCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QIQLLPPEEVARPLRFDPGVIEGALVQKPSQRILSIDQWQSIAVAMRARPDVVVVAPTAS
CEEEECHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GSALAVRGDASRSISITGMEPEQYFRIVRVPDYLVAGEARLGTDDILVGTELAKDLGAGV
CCEEEEECCCCCEEEEECCCHHHHEEEEECCCEEEECCCCCCCCCEEEHHHHHHHHCCCC
GDKLNVTTANGSGRILTITGIFDFGNKAANGRNTYVALRTAQSLLNLIGGVTTIDMTVTD
CCCEEEEEECCCCEEEEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEC
TYAAEDIARDIAAVVPVEADSWITTNAQFFTAVRAQQTSNTLIRLFVGISVAFGIAAVLV
HHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVIQRSKDIGILRAMGASRGRILRVFLIQGGVLGLFGSLLGSAAGAGALILWHHLLRQV
HHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHC
DGSELFPLILEPSLFVAAALLATLTGVVAGLAPAVRAASIDPVEAIRG
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]