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The map label for this gene is ahpC [H]

Identifier: 154248140

GI number: 154248140

Start: 4673544

End: 4674107

Strand: Direct

Name: ahpC [H]

Synonym: Xaut_4220

Alternate gene names: 154248140

Gene position: 4673544-4674107 (Clockwise)

Preceding gene: 154248139

Following gene: 154248141

Centisome position: 88.03

GC content: 61.52

Gene sequence:

>564_bases
ATGTCTCTCGTCAATACTCCGGTCAAGCCTTTCAAGACCACCGCTTTCAAGCAGGGCAAGTTCATCGATGTGTCCGAGGC
GGACCTCGCCGGCAAATGGTCGGTGTTCTTCTTCTACCCGGCCGATTTCACCTTCGTTTGCCCCACCGAGCTCGGTGATC
TCGCCGATCACTACGAAGACTTCAAGAAGCTCGGCGTCGAGATCTATTCCGTCTCCACCGACACTCACTTCACCCATAAG
GCGTGGCACGATTCGTCCGAGACCATCGGCAAGGTGCAGTACGCCATGCTCGGTGACGCCAGCGGCGCCATCACCAACAA
CTTCGAAGTGATGCGCGCGGGCCAGGGCCTCGCCGATCGCGGCACCTTCATCGTGGACCCGAACGGCATCATCCAGGCCG
TGGAAGTCACCGCCGAGGGCATCGGCCGCGACGCTTCCGAGCTTTTGCGGAAGATCAAGGCTGCGCAGTACGTCGCCTCC
CATCCTGGCGAGGTGTGCCCGGCCAAGTGGCAGGAAGGCGAGGCGACCCTTGCCCCCTCGCTCGACCTCGTCGGCAAGAT
CTGA

Upstream 100 bases:

>100_bases
ATCGACAATCTTATCTATTTCATTTATCCCTATCCCGGCCTTATGTTGCGTCGCGAAGGCCCTGGCCTCTCGCACCGCAA
CAGCCATCCAAGGAATTGCC

Downstream 100 bases:

>100_bases
GGCCATCCGGGTCCTTCCATTGGGGAGGACCCACCTCCTCCGCCGCGCGTTCCGCGCGCGGCGGATGCGGAGCACCTTCT
CGTTTTACAAAGCATTCGTC

Product: peroxiredoxin

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLVNTPVKPFKTTAFKQGKFIDVSEADLAGKWSVFFFYPADFTFVCPTELGDLADHYEDFKKLGVEIYSVSTDTHFTHK
AWHDSSETIGKVQYAMLGDASGAITNNFEVMRAGQGLADRGTFIVDPNGIIQAVEVTAEGIGRDASELLRKIKAAQYVAS
HPGEVCPAKWQEGEATLAPSLDLVGKI

Sequences:

>Translated_187_residues
MSLVNTPVKPFKTTAFKQGKFIDVSEADLAGKWSVFFFYPADFTFVCPTELGDLADHYEDFKKLGVEIYSVSTDTHFTHK
AWHDSSETIGKVQYAMLGDASGAITNNFEVMRAGQGLADRGTFIVDPNGIIQAVEVTAEGIGRDASELLRKIKAAQYVAS
HPGEVCPAKWQEGEATLAPSLDLVGKI
>Mature_186_residues
SLVNTPVKPFKTTAFKQGKFIDVSEADLAGKWSVFFFYPADFTFVCPTELGDLADHYEDFKKLGVEIYSVSTDTHFTHKA
WHDSSETIGKVQYAMLGDASGAITNNFEVMRAGQGLADRGTFIVDPNGIIQAVEVTAEGIGRDASELLRKIKAAQYVASH
PGEVCPAKWQEGEATLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=44.5086705202312, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=44.5086705202312, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=40.1098901098901, Blast_Score=154, Evalue=5e-38,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=39.5604395604396, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=39.5604395604396, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=39.5604395604396, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI5453549, Length=187, Percent_Identity=36.8983957219251, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=49.3827160493827, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=78.0748663101604, Blast_Score=324, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=38.2513661202186, Blast_Score=147, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=38.2513661202186, Blast_Score=146, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=40.1129943502825, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=175, Percent_Identity=33.1428571428571, Blast_Score=114, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=32.5714285714286, Blast_Score=111, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6319407, Length=162, Percent_Identity=29.0123456790123, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17738015, Length=184, Percent_Identity=38.5869565217391, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=36.2637362637363, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=36.2637362637363, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI21357347, Length=180, Percent_Identity=35.5555555555556, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=36.1111111111111, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=36.1111111111111, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=29.8701298701299, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20366; Mature: 20235

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVNTPVKPFKTTAFKQGKFIDVSEADLAGKWSVFFFYPADFTFVCPTELGDLADHYED
CCCCCCCCCCCCHHHCCCCCEEECCCCCCCCCEEEEEEECCCEEEECCHHHHHHHHHHHH
FKKLGVEIYSVSTDTHFTHKAWHDSSETIGKVQYAMLGDASGAITNNFEVMRAGQGLADR
HHHHCEEEEEEECCCCEEEHHHCCCCHHHHHEEEEEECCCCCCCCCCEEEEECCCCCCCC
GTFIVDPNGIIQAVEVTAEGIGRDASELLRKIKAAQYVASHPGEVCPAKWQEGEATLAPS
CCEEECCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCC
LDLVGKI
CHHHCCC
>Mature Secondary Structure 
SLVNTPVKPFKTTAFKQGKFIDVSEADLAGKWSVFFFYPADFTFVCPTELGDLADHYED
CCCCCCCCCCCHHHCCCCCEEECCCCCCCCCEEEEEEECCCEEEECCHHHHHHHHHHHH
FKKLGVEIYSVSTDTHFTHKAWHDSSETIGKVQYAMLGDASGAITNNFEVMRAGQGLADR
HHHHCEEEEEEECCCCEEEHHHCCCCHHHHHEEEEEECCCCCCCCCCEEEEECCCCCCCC
GTFIVDPNGIIQAVEVTAEGIGRDASELLRKIKAAQYVASHPGEVCPAKWQEGEATLAPS
CCEEECCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCC
LDLVGKI
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]