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The map label for this gene is guaA [H]

Identifier: 154248018

GI number: 154248018

Start: 4534710

End: 4535558

Strand: Direct

Name: guaA [H]

Synonym: Xaut_4097

Alternate gene names: 154248018

Gene position: 4534710-4535558 (Clockwise)

Preceding gene: 154248015

Following gene: 154248024

Centisome position: 85.42

GC content: 68.67

Gene sequence:

>849_bases
GTGGGCGGGTCAAACCCCGCGTCACACTTTATAATGATACAGGTTCGCGACATCCGCGTCCCGGTGACACCCTTGCCGGC
CTGGCGGACGGTGCGCCAGTATGGGGTGCCCCCGCTCCGCCCGCCCCGGGAGAATCCCTTGAAAGTCCTCGTTTTCCAGC
ACGTAGCCGCCGAGCACCCCGGCAGCTTCCGCGACTTCATGCGCGCCGACGGCGTGATCTGGGACGCTGTGGAGCTGGAC
GAGGGCGAGGCCATTCCAGCGCTCGAGGGTTATGACGCCCTCATGGTGTTCGGCGGCCCCATGGATGTGTGGCAGGAGGA
GGAGCACCCCTGGCTCGTGGCCGAGAAGGCGGCGATCCGGGCGTGGGTGGCCACCGGCAAGCCCTATCTCGGCGTCTGCC
TCGGCCACCAGCTGCTGGCCGATGCGCTGGGCGGCAAGGTGGGCCTCATGCCGCGCCCCGAGGTGGGGGTGACCGACGTG
TCCCTTACGCCGGACGGGCAGGCCTCCGTGTTCTTCACCGGCCTGCCGCCGACCTTCCCGACCCTGCAATGGCACGGCGC
CGCCGTGCTGAAGCAGCCGGAAGGCGCCAAGGTGCTGGCCCACAACGACCATTGCGCCATCCAGGCGCTGCAGGTGGGGG
CGCGGGCCTTCGGCATCCAGTATCATGTGGAGCTGACCGACGACACGGTGCCCGAATGGGGCGAGATCACCGAATATCGC
TGCGCGCTGGAGGCCATCACCGGCCCCGGCGGCGGCGCATTGCTGGTGAAGGCGGTGGAAGAGAAGATGCCGGTGTTCCG
CAAGGCGGCGGAGCAGCTTTACCGGAACTTCCGGGCGACGTGGGGCTGA

Upstream 100 bases:

>100_bases
TCGGCTGGCCGTGCCATGCGCGCCTTGCGCAAGCCTGTTGGCACGGCCCCGCCCGCGGGCGGTGGCTACTCCCCGATGAG
AGGGGGAGTAGCGGGCCGGG

Downstream 100 bases:

>100_bases
AGGCGCATTTGAGCCATCAGGACAGCCGTCGCCCATAACGCACCGTCATGGCCGGGCTCGTCCCGGCCATCCACGCCCTG
CGGCCGGGATGAGCTTTCGC

Product: glutamine amidotransferase class-I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MGGSNPASHFIMIQVRDIRVPVTPLPAWRTVRQYGVPPLRPPRENPLKVLVFQHVAAEHPGSFRDFMRADGVIWDAVELD
EGEAIPALEGYDALMVFGGPMDVWQEEEHPWLVAEKAAIRAWVATGKPYLGVCLGHQLLADALGGKVGLMPRPEVGVTDV
SLTPDGQASVFFTGLPPTFPTLQWHGAAVLKQPEGAKVLAHNDHCAIQALQVGARAFGIQYHVELTDDTVPEWGEITEYR
CALEAITGPGGGALLVKAVEEKMPVFRKAAEQLYRNFRATWG

Sequences:

>Translated_282_residues
MGGSNPASHFIMIQVRDIRVPVTPLPAWRTVRQYGVPPLRPPRENPLKVLVFQHVAAEHPGSFRDFMRADGVIWDAVELD
EGEAIPALEGYDALMVFGGPMDVWQEEEHPWLVAEKAAIRAWVATGKPYLGVCLGHQLLADALGGKVGLMPRPEVGVTDV
SLTPDGQASVFFTGLPPTFPTLQWHGAAVLKQPEGAKVLAHNDHCAIQALQVGARAFGIQYHVELTDDTVPEWGEITEYR
CALEAITGPGGGALLVKAVEEKMPVFRKAAEQLYRNFRATWG
>Mature_281_residues
GGSNPASHFIMIQVRDIRVPVTPLPAWRTVRQYGVPPLRPPRENPLKVLVFQHVAAEHPGSFRDFMRADGVIWDAVELDE
GEAIPALEGYDALMVFGGPMDVWQEEEHPWLVAEKAAIRAWVATGKPYLGVCLGHQLLADALGGKVGLMPRPEVGVTDVS
LTPDGQASVFFTGLPPTFPTLQWHGAAVLKQPEGAKVLAHNDHCAIQALQVGARAFGIQYHVELTDDTVPEWGEITEYRC
ALEAITGPGGGALLVKAVEEKMPVFRKAAEQLYRNFRATWG

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 30826; Mature: 30695

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGSNPASHFIMIQVRDIRVPVTPLPAWRTVRQYGVPPLRPPRENPLKVLVFQHVAAEHP
CCCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHCCC
GSFRDFMRADGVIWDAVELDEGEAIPALEGYDALMVFGGPMDVWQEEEHPWLVAEKAAIR
CHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCEEEEHHHHHE
AWVATGKPYLGVCLGHQLLADALGGKVGLMPRPEVGVTDVSLTPDGQASVFFTGLPPTFP
EEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCC
TLQWHGAAVLKQPEGAKVLAHNDHCAIQALQVGARAFGIQYHVELTDDTVPEWGEITEYR
CEEECCEEEEECCCCCEEEEECCCHHHHHHHHCCEEEEEEEEEEECCCCCCCCCCHHHHH
CALEAITGPGGGALLVKAVEEKMPVFRKAAEQLYRNFRATWG
HEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GGSNPASHFIMIQVRDIRVPVTPLPAWRTVRQYGVPPLRPPRENPLKVLVFQHVAAEHP
CCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHCCC
GSFRDFMRADGVIWDAVELDEGEAIPALEGYDALMVFGGPMDVWQEEEHPWLVAEKAAIR
CHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCEEEEHHHHHE
AWVATGKPYLGVCLGHQLLADALGGKVGLMPRPEVGVTDVSLTPDGQASVFFTGLPPTFP
EEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCC
TLQWHGAAVLKQPEGAKVLAHNDHCAIQALQVGARAFGIQYHVELTDDTVPEWGEITEYR
CEEECCEEEEECCCCCEEEEECCCHHHHHHHHCCEEEEEEEEEEECCCCCCCCCCHHHHH
CALEAITGPGGGALLVKAVEEKMPVFRKAAEQLYRNFRATWG
HEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]