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The map label for this gene is 154247986

Identifier: 154247986

GI number: 154247986

Start: 4499154

End: 4500560

Strand: Direct

Name: 154247986

Synonym: Xaut_4065

Alternate gene names: NA

Gene position: 4499154-4500560 (Clockwise)

Preceding gene: 154247985

Following gene: 154248001

Centisome position: 84.75

GC content: 71.64

Gene sequence:

>1407_bases
ATGTCCGCCGAGTTCGACTCGATGAGCGCCCTCGCCCTGCGCGCTCTGGTGGCCCGGCGCGAGGTCTCGCCGGTGGAACT
GACGCGCCGCGCCCTGGATCGCGCCATCGCCACCCAGCCGACCCTCAACGCCTTCTTCGTCATCTTCGAGGAGGAGGCCA
TGGCCGCCGCCCGCGTCGCCGAGGATGCGGTGATGGCGGGGGCGCCGCTCGGCCTCATCCACGGCCTGCCGTTTTCCGCC
AAGGACCTGATGGCGGTGAAGGGCGCGCCCTATGCCTCCGGCTCCCGTGCCATGGCCGATAACATCGCCGAGGTGGACGC
CCCCGCCGTGGAGCGGGCGAAGGCGCAGGGCGGCATCCTCATCGGCAAGACCACCACCAGCGAATTCGGCTGCAAGCCCA
TCGGGGACAGCCCGCTCACCGGCATCACCCGCAACCCGTGGAACCTCGCCATGACGCCGGGCGGGTCCAGCGCCGGGGCG
GCGGCCTCGGTGGCGGCGGGCATCACCCCGTTTGCGCTGGGCACCGATGGCGGCGGCTCCATCCGCATTCCCTGCGCCTT
CAGCGGGCTGTCGGGCCTCAAGGGCCAGTTCGGCCGGGTGCCGGTGTGGCCCACCTCGGCGACGCCGACGCTGGCCCATG
TGGGACCCATCGCCCGCTCCATGGCGGATGCGGCGCTGTTGTTTTCGGCCGTCGCCGGGCACGACCGGCGCGATCCCTTC
GCCGTCGCCGGTCCGGTTCCGGACGTGATGGGCGCGGCGCTGGCCTCGGTGGCCGGCCTGCGCGTCGCCTACAGCCCCAC
CTTCGGCTATGCCCGCCCCGCGCCCGAGGTGCTCGCGGCCACCGACCGCGCCGCCCGCACCTTCGAGGATTTGGGATGCC
ATGTGGAGCAGGTGGAGCAGGTGTTCGACACCGATCCCGCCGACCTGTGGACGGCGGAATTCTATGCCGGCGTCGGCACC
CGCCTGCGCGACGTGCTGGAAAACCGGCGCGAGCTTCTGGACCCGGCGGTGGCGGACATCCTGATGCCGGCCCTCGGCCA
GGAGATGAAGAGCTATTATGCCAGCGTCTTCGCCCGCTATGCCCTGCGTGAGAAGATGCGCCTGTTCTTCGAGCGCTATG
ATCTCCTCATCTCCCCGGTGCTGCCGGTGAGCGCGCTCGAAGCCGGCCGGAACCTGCCGGAGGGGCTGGAGGACCGCAAC
CTCGTGTCCTGGGTGTTCTACACCTATCCCTTCAACCTCACCGGCCAGCCCGCCGGGGCGGTGTGCGCCGGCCTGTCGCC
GGAGGGCATGCCCATCGGCCTCCAGATCGTCGGCCGCTCCCATTGCGAGGACGACGTGGTGCGCGCGGCAGCCGCCTTCG
AGCGCGCCCAGCCCCCCGGCTACAACCGCCCGCCGGTGGGGGCTTGA

Upstream 100 bases:

>100_bases
GATCGAGACGTATGGGTCTGCTGGATGGTCACTGTCGGCCATCCAGCAGCACTCTTCTTATGGTTCAACGCCAAGACAAA
GCACGCGCCGGAGCAGCCTT

Downstream 100 bases:

>100_bases
AGCGGCCGCGCCGCCGCGTTCAAGGCGGACGTTGCCAAAGCTGAAAATCTGGAGGGGCTTATTGTGGTACAGGTGGGTGG
GCTCGAACCACCGACCTCCG

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSAEFDSMSALALRALVARREVSPVELTRRALDRAIATQPTLNAFFVIFEEEAMAAARVAEDAVMAGAPLGLIHGLPFSA
KDLMAVKGAPYASGSRAMADNIAEVDAPAVERAKAQGGILIGKTTTSEFGCKPIGDSPLTGITRNPWNLAMTPGGSSAGA
AASVAAGITPFALGTDGGGSIRIPCAFSGLSGLKGQFGRVPVWPTSATPTLAHVGPIARSMADAALLFSAVAGHDRRDPF
AVAGPVPDVMGAALASVAGLRVAYSPTFGYARPAPEVLAATDRAARTFEDLGCHVEQVEQVFDTDPADLWTAEFYAGVGT
RLRDVLENRRELLDPAVADILMPALGQEMKSYYASVFARYALREKMRLFFERYDLLISPVLPVSALEAGRNLPEGLEDRN
LVSWVFYTYPFNLTGQPAGAVCAGLSPEGMPIGLQIVGRSHCEDDVVRAAAAFERAQPPGYNRPPVGA

Sequences:

>Translated_468_residues
MSAEFDSMSALALRALVARREVSPVELTRRALDRAIATQPTLNAFFVIFEEEAMAAARVAEDAVMAGAPLGLIHGLPFSA
KDLMAVKGAPYASGSRAMADNIAEVDAPAVERAKAQGGILIGKTTTSEFGCKPIGDSPLTGITRNPWNLAMTPGGSSAGA
AASVAAGITPFALGTDGGGSIRIPCAFSGLSGLKGQFGRVPVWPTSATPTLAHVGPIARSMADAALLFSAVAGHDRRDPF
AVAGPVPDVMGAALASVAGLRVAYSPTFGYARPAPEVLAATDRAARTFEDLGCHVEQVEQVFDTDPADLWTAEFYAGVGT
RLRDVLENRRELLDPAVADILMPALGQEMKSYYASVFARYALREKMRLFFERYDLLISPVLPVSALEAGRNLPEGLEDRN
LVSWVFYTYPFNLTGQPAGAVCAGLSPEGMPIGLQIVGRSHCEDDVVRAAAAFERAQPPGYNRPPVGA
>Mature_467_residues
SAEFDSMSALALRALVARREVSPVELTRRALDRAIATQPTLNAFFVIFEEEAMAAARVAEDAVMAGAPLGLIHGLPFSAK
DLMAVKGAPYASGSRAMADNIAEVDAPAVERAKAQGGILIGKTTTSEFGCKPIGDSPLTGITRNPWNLAMTPGGSSAGAA
ASVAAGITPFALGTDGGGSIRIPCAFSGLSGLKGQFGRVPVWPTSATPTLAHVGPIARSMADAALLFSAVAGHDRRDPFA
VAGPVPDVMGAALASVAGLRVAYSPTFGYARPAPEVLAATDRAARTFEDLGCHVEQVEQVFDTDPADLWTAEFYAGVGTR
LRDVLENRRELLDPAVADILMPALGQEMKSYYASVFARYALREKMRLFFERYDLLISPVLPVSALEAGRNLPEGLEDRNL
VSWVFYTYPFNLTGQPAGAVCAGLSPEGMPIGLQIVGRSHCEDDVVRAAAAFERAQPPGYNRPPVGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=494, Percent_Identity=25.7085020242915, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI195972892, Length=471, Percent_Identity=24.203821656051, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI166795287, Length=231, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17538252, Length=386, Percent_Identity=25.9067357512953, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17543272, Length=439, Percent_Identity=24.8291571753986, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17556264, Length=342, Percent_Identity=27.1929824561404, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537465, Length=504, Percent_Identity=23.015873015873, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990152, Length=407, Percent_Identity=26.044226044226, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556278, Length=359, Percent_Identity=25.0696378830084, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17556276, Length=359, Percent_Identity=25.0696378830084, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538254, Length=289, Percent_Identity=26.2975778546713, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6319685, Length=383, Percent_Identity=27.4151436031332, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320448, Length=511, Percent_Identity=24.853228962818, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323950, Length=169, Percent_Identity=32.5443786982249, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161078093, Length=500, Percent_Identity=27.8, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24648435, Length=490, Percent_Identity=25.7142857142857, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24648437, Length=490, Percent_Identity=25.7142857142857, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI45550774, Length=496, Percent_Identity=25.4032258064516, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644968, Length=497, Percent_Identity=26.7605633802817, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24648441, Length=418, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24648439, Length=418, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24648113, Length=484, Percent_Identity=26.0330578512397, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356731, Length=424, Percent_Identity=26.8867924528302, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24652985, Length=501, Percent_Identity=25.3493013972056, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19922090, Length=501, Percent_Identity=25.3493013972056, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24652981, Length=501, Percent_Identity=25.3493013972056, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24652983, Length=501, Percent_Identity=25.3493013972056, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 49236; Mature: 49104

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEFDSMSALALRALVARREVSPVELTRRALDRAIATQPTLNAFFVIFEEEAMAAARVA
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHH
EDAVMAGAPLGLIHGLPFSAKDLMAVKGAPYASGSRAMADNIAEVDAPAVERAKAQGGIL
HHHHHCCCCHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEE
IGKTTTSEFGCKPIGDSPLTGITRNPWNLAMTPGGSSAGAAASVAAGITPFALGTDGGGS
EEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCEEEECCCCCE
IRIPCAFSGLSGLKGQFGRVPVWPTSATPTLAHVGPIARSMADAALLFSAVAGHDRRDPF
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AVAGPVPDVMGAALASVAGLRVAYSPTFGYARPAPEVLAATDRAARTFEDLGCHVEQVEQ
EECCCCHHHHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
VFDTDPADLWTAEFYAGVGTRLRDVLENRRELLDPAVADILMPALGQEMKSYYASVFARY
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALREKMRLFFERYDLLISPVLPVSALEAGRNLPEGLEDRNLVSWVFYTYPFNLTGQPAGA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
VCAGLSPEGMPIGLQIVGRSHCEDDVVRAAAAFERAQPPGYNRPPVGA
EEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAEFDSMSALALRALVARREVSPVELTRRALDRAIATQPTLNAFFVIFEEEAMAAARVA
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHH
EDAVMAGAPLGLIHGLPFSAKDLMAVKGAPYASGSRAMADNIAEVDAPAVERAKAQGGIL
HHHHHCCCCHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEE
IGKTTTSEFGCKPIGDSPLTGITRNPWNLAMTPGGSSAGAAASVAAGITPFALGTDGGGS
EEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCEEEECCCCCE
IRIPCAFSGLSGLKGQFGRVPVWPTSATPTLAHVGPIARSMADAALLFSAVAGHDRRDPF
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AVAGPVPDVMGAALASVAGLRVAYSPTFGYARPAPEVLAATDRAARTFEDLGCHVEQVEQ
EECCCCHHHHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
VFDTDPADLWTAEFYAGVGTRLRDVLENRRELLDPAVADILMPALGQEMKSYYASVFARY
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALREKMRLFFERYDLLISPVLPVSALEAGRNLPEGLEDRNLVSWVFYTYPFNLTGQPAGA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
VCAGLSPEGMPIGLQIVGRSHCEDDVVRAAAAFERAQPPGYNRPPVGA
EEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]