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The map label for this gene is acoR [H]

Identifier: 154247967

GI number: 154247967

Start: 4474858

End: 4476864

Strand: Direct

Name: acoR [H]

Synonym: Xaut_4046

Alternate gene names: 154247967

Gene position: 4474858-4476864 (Clockwise)

Preceding gene: 154247959

Following gene: 154247974

Centisome position: 84.29

GC content: 71.45

Gene sequence:

>2007_bases
ATGAAGCGGGAGCAGGCCGCGCACATCGATGAGCTGGTGCGCGCGGCGAGCGGGCACGGCTCGCGCCGCGATGCCATCAT
CGAGGCGTCGTGGCGGCGCTGCGTCAACGAGCACAACCTCGACCCGGTGGTGCTGCGCGACCCGTGCATCGTTACCCATG
CCCGCCTGCGCGAGCATCAGGAGGCCATGGACGAGTTCCTGCACACGGCGCGCTTCGGGGTGGAGACGCTTTATCGCGAG
GTGGCGGGCCTCGGCTACGTGCTGCTGCTCACCGATGCCAAGGGCATCACGGTGGATTTCATCGGCGATCCCACCTTCGA
CAGCAACCTCATGCGCGCCGGCCTCTATCTCGGCGCCGACTGGAACGAGCCGCATGCCGGCACCTGCGCGGTGGGCACCT
GCATCGCCACCGGCGAGGCGCTGGTGGTGCACCAGTCCGACCATTTCGACGCCACCCACATCCCGCTGACCTGCACGGCC
GCGCCGGTGTTCGACCCCAGCGGCGCGCTGGCGGCGGTGCTGGACATCTCGGCGCTGCATTCGCCGCAGCCCAAGGAGAG
CCAGTATCTGGCGTTGCAGTTCGTCAAATCCGTCGCCCACAAGATCGAGACGGCGCACCTTCTCAACCGCTTCCGCCGCG
AATGGATCGTGAAGCTCGCGCCCTCGCCGGAATTTGCCGACGTGGACCCGGCCTATGTGCTGGCGGTGGATGGATCGGGC
CGCATCCTCGGCTTCAACAACCGCACCCGCCAGCTCATGATGCGCGAGCTGGAGTGCCGCCCCGCCCTGGCCGACGGGCG
GCCGCTCGCCGGCCGACCCCTGTCCGAGTTCTTCGACCTCCAGGTGGACGACCTGCCGCGCCTCATGCCGTCGCGGCCGG
CGTCGCAGCGCATGGTGCGCCTCGCCCTCTCCGGCACGCCCTTGTTCGCGCAGGCCCAGCAGCCGCCGGCGCGTGTCGCC
TCGCCCTCGCCTCTTGCCCCCGCGCCGGTCCTGCCGAAGCCTTTGGAAGCCCTCACCTGCGGCGATGGCGCCATGCTGGA
GGTGGCGGCGCGGGCGGCCAAGCTCGTCAACACCCAGATGAGCCTGCTCATCTGCGGCGAGACCGGCACCGGCAAGGAGC
ATCTGGCCAAAGCCATCCATGCCGCGAGCGGTCGTGCCGGCAAGCCGTTCGTGCCGGTGAACTGCGCAGCGCTGCCGGAG
ACGCTGATCGAGGGCGAATTGTTCGGCTACGAGCCGGGCGCCTTCACCGGCGCCGCCGCCAAGGGCAAGCGCGGCCTCGT
CATGGAGGCGGACGGCGGCACCCTCTTCCTCGACGAGATCGGCGACATGCCGCTGACCCTCCAGACCCGCCTGTTGCGGG
TGCTGGCCGAGCGCGAGGTGACGCCCATCGGCCGCACCCGTCCGGTGCCGGTGAACATCCGCGTCATCGCCGCCACCCAC
CGCGACCTCATCGCCGAGGTGAAGGCCGGGCGCTTCCGCGAGGACCTCTATTTCCGCCTCAGCGGCGGCGTGCTCGCTTT
GCCGGCCCTGCGCCAGCGCGCGGATCTCGACTGGCTGGTGGCGCGGTTTCTGGCCGAGCGGGGCGGGGTGCTGCGGGTGC
CGTTCGAGCTGTCGGGCGAGGCGCGGGCGGCGCTGCACGCCTATGCGTGGCCCGGCAACATCCGCGAGCTGGCCAATGCG
CTGGACTATGCCTGCGCGGTGGCGGGCGACGCCGTCATCGCCTGGGACGACCTGCCCGACCGCATCCGCCACGCGGCGCC
GGTGGCGACTGGGCCGTGTGGGACGGCGCCTGTGGCGCTCCTCGCCGGGTCTTCTGCCGTTGGCGGGATGGCGGCCGGTG
GCACCAGTCCGGACGAGCGCGGCGCCCTGCTGGCGCTTCTTGCCGCCCAGCGCTGGAACGTCTCGGCGGTGGCCCGCGCG
CTGGGCGTGGACCGCACCACCATCCACCGCCGCATGCGCCGCTTGGGGATCACCTCGCCACGGCATGGGGACGAGGGGGG
CAACTGA

Upstream 100 bases:

>100_bases
GACTTGAGGGAGCCCGCGCCAGCACATTTGCCGCGCCCCTTGCCGCCGCCGCCGATCAGGGCGAGACTTCCGGCAAAAGG
AACGGTCTGGGAGGATCGTC

Downstream 100 bases:

>100_bases
GGGCAGCCCGGAGCTTCAAGGCGGACGGTTTCGCCTGGCGCGGTCTGCTCCCTCTCCCGCCTGCGGGGGAGGGGCCCATG
TTGCGCCCCGGTCCTGACAG

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MKREQAAHIDELVRAASGHGSRRDAIIEASWRRCVNEHNLDPVVLRDPCIVTHARLREHQEAMDEFLHTARFGVETLYRE
VAGLGYVLLLTDAKGITVDFIGDPTFDSNLMRAGLYLGADWNEPHAGTCAVGTCIATGEALVVHQSDHFDATHIPLTCTA
APVFDPSGALAAVLDISALHSPQPKESQYLALQFVKSVAHKIETAHLLNRFRREWIVKLAPSPEFADVDPAYVLAVDGSG
RILGFNNRTRQLMMRELECRPALADGRPLAGRPLSEFFDLQVDDLPRLMPSRPASQRMVRLALSGTPLFAQAQQPPARVA
SPSPLAPAPVLPKPLEALTCGDGAMLEVAARAAKLVNTQMSLLICGETGTGKEHLAKAIHAASGRAGKPFVPVNCAALPE
TLIEGELFGYEPGAFTGAAAKGKRGLVMEADGGTLFLDEIGDMPLTLQTRLLRVLAEREVTPIGRTRPVPVNIRVIAATH
RDLIAEVKAGRFREDLYFRLSGGVLALPALRQRADLDWLVARFLAERGGVLRVPFELSGEARAALHAYAWPGNIRELANA
LDYACAVAGDAVIAWDDLPDRIRHAAPVATGPCGTAPVALLAGSSAVGGMAAGGTSPDERGALLALLAAQRWNVSAVARA
LGVDRTTIHRRMRRLGITSPRHGDEGGN

Sequences:

>Translated_668_residues
MKREQAAHIDELVRAASGHGSRRDAIIEASWRRCVNEHNLDPVVLRDPCIVTHARLREHQEAMDEFLHTARFGVETLYRE
VAGLGYVLLLTDAKGITVDFIGDPTFDSNLMRAGLYLGADWNEPHAGTCAVGTCIATGEALVVHQSDHFDATHIPLTCTA
APVFDPSGALAAVLDISALHSPQPKESQYLALQFVKSVAHKIETAHLLNRFRREWIVKLAPSPEFADVDPAYVLAVDGSG
RILGFNNRTRQLMMRELECRPALADGRPLAGRPLSEFFDLQVDDLPRLMPSRPASQRMVRLALSGTPLFAQAQQPPARVA
SPSPLAPAPVLPKPLEALTCGDGAMLEVAARAAKLVNTQMSLLICGETGTGKEHLAKAIHAASGRAGKPFVPVNCAALPE
TLIEGELFGYEPGAFTGAAAKGKRGLVMEADGGTLFLDEIGDMPLTLQTRLLRVLAEREVTPIGRTRPVPVNIRVIAATH
RDLIAEVKAGRFREDLYFRLSGGVLALPALRQRADLDWLVARFLAERGGVLRVPFELSGEARAALHAYAWPGNIRELANA
LDYACAVAGDAVIAWDDLPDRIRHAAPVATGPCGTAPVALLAGSSAVGGMAAGGTSPDERGALLALLAAQRWNVSAVARA
LGVDRTTIHRRMRRLGITSPRHGDEGGN
>Mature_668_residues
MKREQAAHIDELVRAASGHGSRRDAIIEASWRRCVNEHNLDPVVLRDPCIVTHARLREHQEAMDEFLHTARFGVETLYRE
VAGLGYVLLLTDAKGITVDFIGDPTFDSNLMRAGLYLGADWNEPHAGTCAVGTCIATGEALVVHQSDHFDATHIPLTCTA
APVFDPSGALAAVLDISALHSPQPKESQYLALQFVKSVAHKIETAHLLNRFRREWIVKLAPSPEFADVDPAYVLAVDGSG
RILGFNNRTRQLMMRELECRPALADGRPLAGRPLSEFFDLQVDDLPRLMPSRPASQRMVRLALSGTPLFAQAQQPPARVA
SPSPLAPAPVLPKPLEALTCGDGAMLEVAARAAKLVNTQMSLLICGETGTGKEHLAKAIHAASGRAGKPFVPVNCAALPE
TLIEGELFGYEPGAFTGAAAKGKRGLVMEADGGTLFLDEIGDMPLTLQTRLLRVLAEREVTPIGRTRPVPVNIRVIAATH
RDLIAEVKAGRFREDLYFRLSGGVLALPALRQRADLDWLVARFLAERGGVLRVPFELSGEARAALHAYAWPGNIRELANA
LDYACAVAGDAVIAWDDLPDRIRHAAPVATGPCGTAPVALLAGSSAVGGMAAGGTSPDERGALLALLAAQRWNVSAVARA
LGVDRTTIHRRMRRLGITSPRHGDEGGN

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=317, Percent_Identity=43.5331230283912, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789233, Length=428, Percent_Identity=35.0467289719626, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1790437, Length=322, Percent_Identity=42.5465838509317, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1788905, Length=321, Percent_Identity=39.8753894080997, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI87082117, Length=321, Percent_Identity=40.4984423676012, Blast_Score=209, Evalue=6e-55,
Organism=Escherichia coli, GI87082152, Length=304, Percent_Identity=44.078947368421, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1790299, Length=325, Percent_Identity=41.5384615384615, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1786524, Length=218, Percent_Identity=53.2110091743119, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI1789087, Length=321, Percent_Identity=39.2523364485981, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1787583, Length=326, Percent_Identity=37.7300613496933, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI87081872, Length=239, Percent_Identity=41.8410041841004, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1789828, Length=256, Percent_Identity=37.109375, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI87081858, Length=666, Percent_Identity=23.2732732732733, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 71736; Mature: 71736

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKREQAAHIDELVRAASGHGSRRDAIIEASWRRCVNEHNLDPVVLRDPCIVTHARLREHQ
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
EAMDEFLHTARFGVETLYREVAGLGYVLLLTDAKGITVDFIGDPTFDSNLMRAGLYLGAD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCHHHHCCEEECCC
WNEPHAGTCAVGTCIATGEALVVHQSDHFDATHIPLTCTAAPVFDPSGALAAVLDISALH
CCCCCCCCHHHHHHEECCCEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHC
SPQPKESQYLALQFVKSVAHKIETAHLLNRFRREWIVKLAPSPEFADVDPAYVLAVDGSG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCC
RILGFNNRTRQLMMRELECRPALADGRPLAGRPLSEFFDLQVDDLPRLMPSRPASQRMVR
CEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHCCCCCHHHHHEE
LALSGTPLFAQAQQPPARVASPSPLAPAPVLPKPLEALTCGDGAMLEVAARAAKLVNTQM
EEECCCCCEEECCCCCHHCCCCCCCCCCCCCCCCHHHEECCCCHHHHHHHHHHHHHCCCE
SLLICGETGTGKEHLAKAIHAASGRAGKPFVPVNCAALPETLIEGELFGYEPGAFTGAAA
EEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCC
KGKRGLVMEADGGTLFLDEIGDMPLTLQTRLLRVLAEREVTPIGRTRPVPVNIRVIAATH
CCCCCEEEECCCCEEEHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECH
RDLIAEVKAGRFREDLYFRLSGGVLALPALRQRADLDWLVARFLAERGGVLRVPFELSGE
HHHHHHHHCCCCCCCEEEEECCCEEECCHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCC
ARAALHAYAWPGNIRELANALDYACAVAGDAVIAWDDLPDRIRHAAPVATGPCGTAPVAL
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCCCCHHE
LAGSSAVGGMAAGGTSPDERGALLALLAAQRWNVSAVARALGVDRTTIHRRMRRLGITSP
EECCCCCCCEECCCCCCCCCCHHEEEHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCC
RHGDEGGN
CCCCCCCC
>Mature Secondary Structure
MKREQAAHIDELVRAASGHGSRRDAIIEASWRRCVNEHNLDPVVLRDPCIVTHARLREHQ
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
EAMDEFLHTARFGVETLYREVAGLGYVLLLTDAKGITVDFIGDPTFDSNLMRAGLYLGAD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCHHHHCCEEECCC
WNEPHAGTCAVGTCIATGEALVVHQSDHFDATHIPLTCTAAPVFDPSGALAAVLDISALH
CCCCCCCCHHHHHHEECCCEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHC
SPQPKESQYLALQFVKSVAHKIETAHLLNRFRREWIVKLAPSPEFADVDPAYVLAVDGSG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCC
RILGFNNRTRQLMMRELECRPALADGRPLAGRPLSEFFDLQVDDLPRLMPSRPASQRMVR
CEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHCCCCCHHHHHEE
LALSGTPLFAQAQQPPARVASPSPLAPAPVLPKPLEALTCGDGAMLEVAARAAKLVNTQM
EEECCCCCEEECCCCCHHCCCCCCCCCCCCCCCCHHHEECCCCHHHHHHHHHHHHHCCCE
SLLICGETGTGKEHLAKAIHAASGRAGKPFVPVNCAALPETLIEGELFGYEPGAFTGAAA
EEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCC
KGKRGLVMEADGGTLFLDEIGDMPLTLQTRLLRVLAEREVTPIGRTRPVPVNIRVIAATH
CCCCCEEEECCCCEEEHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECH
RDLIAEVKAGRFREDLYFRLSGGVLALPALRQRADLDWLVARFLAERGGVLRVPFELSGE
HHHHHHHHCCCCCCCEEEEECCCEEECCHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCC
ARAALHAYAWPGNIRELANALDYACAVAGDAVIAWDDLPDRIRHAAPVATGPCGTAPVAL
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCCCCHHE
LAGSSAVGGMAAGGTSPDERGALLALLAAQRWNVSAVARALGVDRTTIHRRMRRLGITSP
EECCCCCCCEECCCCCCCCCCHHEEEHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCC
RHGDEGGN
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]