Click here to switch to the map view.

The map label for this gene is arsC [H]

Identifier: 154247881

GI number: 154247881

Start: 4381097

End: 4381984

Strand: Direct

Name: arsC [H]

Synonym: Xaut_3958

Alternate gene names: 154247881

Gene position: 4381097-4381984 (Clockwise)

Preceding gene: 154247880

Following gene: 154247882

Centisome position: 82.52

GC content: 64.3

Gene sequence:

>888_bases
ATGGACGAGACGAAGCTGAATGGGGAAGACGCCACGCGGATCTTCGATGCGCTGTCCCAAGGCACGCGCTTCGAGACTTA
TCGTCTTCTGCTGCGCTATGTGCCCTATGGCCTTCAGGCGGGCGACATCGCCCGCCTGCTAGCGGTAGCGCACAATACCA
TGTCGGTGCACCTCGGCGTGCTGGAGCGTGCCGGCCTTGTCACGTCGCGGCGCGAGGGACGGTCCATCATCTATGCCGTC
AGCTTGTCCACAGCGGGCCCTGTGCTGAGCCAACTCATGGCGGAGATGGGTTTTGCCGTCTCCCCCCGGTGCGGGACCGG
CCCCGCGGCCTTTCCGCAGCTGCGTCCTGCCGCCGGGAATGATCGCGTCTACAATGTTCTGCTAGTCTGCTCGGCCAACT
CGGCACGGTCGCTGATCGCGGAGGCGTTGCTCAACCGCGAGGGGCGAGGCCGCTTCAAGGCCTACTCGGCCGGCAGTCGG
CCGAAGCTCAAGCCGCACTCGATGGCTATCGATCTGCTTGACTCGCTCGGCTACGATACGACGAACCTCGCCTCCAAGAG
CTGGGATGGGTTCGCCAAGCCGGATGCGCCCCAGATGGATTTCGTCATCACCACCTGCGACGCCGCGGCCGGGGAAATCT
GCCCTGCCTTTCCCGGTCATCCGCTACAGGCCCATTGGGGCCTGCCCGACCCGATCCGGGTGAAGGGAACCGAAGCTGAG
CAGAAGGCTGCCTTCGTTGCCACCTACCGTCGGCTCGCCGGGCGTATCTCCGCCTTCGTCAACCTGCCATTTGAGCAACT
CGATCTTGCTTCGCTCAAGGAGCGCATCGGCGAGATCGGGAAAATGGAGGGAGCGACGGATCTCACACTCTCGGGACAGG
CCGCGTGA

Upstream 100 bases:

>100_bases
TCTGGTCCAGCAGGTCAAGGACTATTGGGCCAGGACCTTCAAGGGCGGTGCCTGAGGCACTTGGGCTGACGCGTGAGCAG
CATTCGAACGGTGAGACAAG

Downstream 100 bases:

>100_bases
GCTGTCGTCGTCCTGAAACAGACCGCGCCCACGCTCTCGCCGCAATCGGCCGCAGCTGACGGCCTTGGGAGATCCCGCAC
CGTGTCCGTGTTTGAACGCT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDETKLNGEDATRIFDALSQGTRFETYRLLLRYVPYGLQAGDIARLLAVAHNTMSVHLGVLERAGLVTSRREGRSIIYAV
SLSTAGPVLSQLMAEMGFAVSPRCGTGPAAFPQLRPAAGNDRVYNVLLVCSANSARSLIAEALLNREGRGRFKAYSAGSR
PKLKPHSMAIDLLDSLGYDTTNLASKSWDGFAKPDAPQMDFVITTCDAAAGEICPAFPGHPLQAHWGLPDPIRVKGTEAE
QKAAFVATYRRLAGRISAFVNLPFEQLDLASLKERIGEIGKMEGATDLTLSGQAA

Sequences:

>Translated_295_residues
MDETKLNGEDATRIFDALSQGTRFETYRLLLRYVPYGLQAGDIARLLAVAHNTMSVHLGVLERAGLVTSRREGRSIIYAV
SLSTAGPVLSQLMAEMGFAVSPRCGTGPAAFPQLRPAAGNDRVYNVLLVCSANSARSLIAEALLNREGRGRFKAYSAGSR
PKLKPHSMAIDLLDSLGYDTTNLASKSWDGFAKPDAPQMDFVITTCDAAAGEICPAFPGHPLQAHWGLPDPIRVKGTEAE
QKAAFVATYRRLAGRISAFVNLPFEQLDLASLKERIGEIGKMEGATDLTLSGQAA
>Mature_295_residues
MDETKLNGEDATRIFDALSQGTRFETYRLLLRYVPYGLQAGDIARLLAVAHNTMSVHLGVLERAGLVTSRREGRSIIYAV
SLSTAGPVLSQLMAEMGFAVSPRCGTGPAAFPQLRPAAGNDRVYNVLLVCSANSARSLIAEALLNREGRGRFKAYSAGSR
PKLKPHSMAIDLLDSLGYDTTNLASKSWDGFAKPDAPQMDFVITTCDAAAGEICPAFPGHPLQAHWGLPDPIRVKGTEAE
QKAAFVATYRRLAGRISAFVNLPFEQLDLASLKERIGEIGKMEGATDLTLSGQAA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 31711; Mature: 31711

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDETKLNGEDATRIFDALSQGTRFETYRLLLRYVPYGLQAGDIARLLAVAHNTMSVHLGV
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHEEEHHH
LERAGLVTSRREGRSIIYAVSLSTAGPVLSQLMAEMGFAVSPRCGTGPAAFPQLRPAAGN
HHHHCCHHCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCC
DRVYNVLLVCSANSARSLIAEALLNREGRGRFKAYSAGSRPKLKPHSMAIDLLDSLGYDT
CCEEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCC
TNLASKSWDGFAKPDAPQMDFVITTCDAAAGEICPAFPGHPLQAHWGLPDPIRVKGTEAE
HHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCEEECCCCHH
QKAAFVATYRRLAGRISAFVNLPFEQLDLASLKERIGEIGKMEGATDLTLSGQAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
>Mature Secondary Structure
MDETKLNGEDATRIFDALSQGTRFETYRLLLRYVPYGLQAGDIARLLAVAHNTMSVHLGV
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHEEEHHH
LERAGLVTSRREGRSIIYAVSLSTAGPVLSQLMAEMGFAVSPRCGTGPAAFPQLRPAAGN
HHHHCCHHCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCC
DRVYNVLLVCSANSARSLIAEALLNREGRGRFKAYSAGSRPKLKPHSMAIDLLDSLGYDT
CCEEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCC
TNLASKSWDGFAKPDAPQMDFVITTCDAAAGEICPAFPGHPLQAHWGLPDPIRVKGTEAE
HHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCEEECCCCHH
QKAAFVATYRRLAGRISAFVNLPFEQLDLASLKERIGEIGKMEGATDLTLSGQAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]