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The map label for this gene is kinA [H]

Identifier: 154247870

GI number: 154247870

Start: 4367584

End: 4369035

Strand: Direct

Name: kinA [H]

Synonym: Xaut_3947

Alternate gene names: 154247870

Gene position: 4367584-4369035 (Clockwise)

Preceding gene: 154247869

Following gene: 154247871

Centisome position: 82.27

GC content: 67.84

Gene sequence:

>1452_bases
ATGATCACGCGCCTCGACCCTCGCCAGTGGCCCGTCACCCTCAAGGTGCCTTTGGCGGTTGCGGCGCTCATGGTGCTGGT
TGGGCTTGCCCTGTCCGAGCGCGTGCTGAGCCGGCTGGGGGAGACGCAGGAGCGCCAGTTGCGCGCTTTGGCGCAAACCT
ATCTGGACAGCCTCTCCTCCGCGGTCGCGCCCGCGATCCTGAGAGACGATGTCTGGGAAGTCTATGACGCCGTCATGCGG
GCACAAGATCTCAACAAGAGCCTGCATCCATTGAGCGCCGTGATCACCGACGCGGAAGGCCTCATCATCGCGGCGTCCGA
TCCCCGCCGCTTCCCCGTTGGGGCGCGTCTCCCGTCGGATCTTGCTTCGCTCGGTGCCGGCCGGGATTTCAGCTTCGAGG
CTGGCGCCAGATCCGCCACCGCGACGCGCGTGCTTTCCTATCCTGGACGTATCGTCGGAATCATCCACGCCACTTTCGAC
ACCAGCCATCTGGCTTTGGAGCGGCGCGACGTCGTCATCGCGCTCGCGGCCACGAACGGGATGGTCACGCTGCTGCTCGC
CGTGGCCGGCTGGTTGCTCGTCGCCCGCATGATGGCGCCGGTGCGCACGCTCTCGCGCTATCTGGGCGCTGCGAGCGAAG
GGCGGGCGACGCCCGTTCCCCCGGAGGCGGTCGCGCGCAACGGCGCTGAATTCGCCCGCCTGTTCCTAGCCTACAATGCG
CTGGTCCGGTCCATGTACGAGCGGGAGGACCTAGCCCGACAATTGGCGGACGAGCATCGGCTCGGCAGCCTCGGGCGGCT
CACCTCGGCGCTCGCCCACGAGATCAACAACCCGCTGGGCGGCCTTTTCAACGCGCTGGCGACGCTGAAGACCCATGGAC
ACCATGCGGCGGTCCGAAAATCGTCCCTCGGCCTTCTCGAACGAGGCCTCGTCGGTATCCGCGACGTGGTGCGCACCACC
CTCGCTTTGTATCGGCCGGAGCAGGCGCCGCGACCCCTCGCCATGGCCGATTTCGAGGACCTGCAGCTACTGATTGCCCC
CGCGGCGCGCCGGAAGGGTGTCGATCTGAGGTTCTCCGGTCCCGTCGACGTGTTGCTTCCTCTGCCCAGCACCCCGGTGC
GCCAGGCCGTGCTGAACCTGCTGCTGAATGCGGTTTCCGCCGCCCCGCCGGGAAGCGAAGTGGCGGTGGATGCGTCGCTC
ACGCCGACGGCCCTGCATGTAATCGTGTCGGATCGAGGCAGCGGCCTGCCCGAGCCTGCGGGGTGCCTTCTTGCGGCTGG
CGGGGAAACGGGTGGCCCACTCTGGGGCGGCGGCCTCGGCTTGTGGACCACCCGGCGCATCCTGGACGACCTCGGTGCCT
CGGCCGAGGTCGAGCGGCCTGAAACGGGGGGAACGCGGATCCGTCTTCTCTTCCCTTTCATCGCCCCAATGGAGCTCGCC
CATGTCGCATGA

Upstream 100 bases:

>100_bases
TCGCCATGCTGCGGCTCGACGGGTTTGTGCAGCGGGAGGCGAGCCTCTTCGATCCAATTGCCGCAAAGGCGGCGCTCGTT
GCGGGCACCGGGTGACGCCC

Downstream 100 bases:

>100_bases
GCCTCCCGTCATCGGCCTCGTGGAGGACGATCCCATCATGGGCGAGAGCCTCGCGCAGCGGCTCGGCCTGGAGGGAATGA
GGGTGCATTGGTGGCGGACC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Stage II sporulation protein F; Stage II sporulation protein J [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MITRLDPRQWPVTLKVPLAVAALMVLVGLALSERVLSRLGETQERQLRALAQTYLDSLSSAVAPAILRDDVWEVYDAVMR
AQDLNKSLHPLSAVITDAEGLIIAASDPRRFPVGARLPSDLASLGAGRDFSFEAGARSATATRVLSYPGRIVGIIHATFD
TSHLALERRDVVIALAATNGMVTLLLAVAGWLLVARMMAPVRTLSRYLGAASEGRATPVPPEAVARNGAEFARLFLAYNA
LVRSMYEREDLARQLADEHRLGSLGRLTSALAHEINNPLGGLFNALATLKTHGHHAAVRKSSLGLLERGLVGIRDVVRTT
LALYRPEQAPRPLAMADFEDLQLLIAPAARRKGVDLRFSGPVDVLLPLPSTPVRQAVLNLLLNAVSAAPPGSEVAVDASL
TPTALHVIVSDRGSGLPEPAGCLLAAGGETGGPLWGGGLGLWTTRRILDDLGASAEVERPETGGTRIRLLFPFIAPMELA
HVA

Sequences:

>Translated_483_residues
MITRLDPRQWPVTLKVPLAVAALMVLVGLALSERVLSRLGETQERQLRALAQTYLDSLSSAVAPAILRDDVWEVYDAVMR
AQDLNKSLHPLSAVITDAEGLIIAASDPRRFPVGARLPSDLASLGAGRDFSFEAGARSATATRVLSYPGRIVGIIHATFD
TSHLALERRDVVIALAATNGMVTLLLAVAGWLLVARMMAPVRTLSRYLGAASEGRATPVPPEAVARNGAEFARLFLAYNA
LVRSMYEREDLARQLADEHRLGSLGRLTSALAHEINNPLGGLFNALATLKTHGHHAAVRKSSLGLLERGLVGIRDVVRTT
LALYRPEQAPRPLAMADFEDLQLLIAPAARRKGVDLRFSGPVDVLLPLPSTPVRQAVLNLLLNAVSAAPPGSEVAVDASL
TPTALHVIVSDRGSGLPEPAGCLLAAGGETGGPLWGGGLGLWTTRRILDDLGASAEVERPETGGTRIRLLFPFIAPMELA
HVA
>Mature_483_residues
MITRLDPRQWPVTLKVPLAVAALMVLVGLALSERVLSRLGETQERQLRALAQTYLDSLSSAVAPAILRDDVWEVYDAVMR
AQDLNKSLHPLSAVITDAEGLIIAASDPRRFPVGARLPSDLASLGAGRDFSFEAGARSATATRVLSYPGRIVGIIHATFD
TSHLALERRDVVIALAATNGMVTLLLAVAGWLLVARMMAPVRTLSRYLGAASEGRATPVPPEAVARNGAEFARLFLAYNA
LVRSMYEREDLARQLADEHRLGSLGRLTSALAHEINNPLGGLFNALATLKTHGHHAAVRKSSLGLLERGLVGIRDVVRTT
LALYRPEQAPRPLAMADFEDLQLLIAPAARRKGVDLRFSGPVDVLLPLPSTPVRQAVLNLLLNAVSAAPPGSEVAVDASL
TPTALHVIVSDRGSGLPEPAGCLLAAGGETGGPLWGGGLGLWTTRRILDDLGASAEVERPETGGTRIRLLFPFIAPMELA
HVA

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51447; Mature: 51447

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITRLDPRQWPVTLKVPLAVAALMVLVGLALSERVLSRLGETQERQLRALAQTYLDSLSS
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AVAPAILRDDVWEVYDAVMRAQDLNKSLHPLSAVITDAEGLIIAASDPRRFPVGARLPSD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHH
LASLGAGRDFSFEAGARSATATRVLSYPGRIVGIIHATFDTSHLALERRDVVIALAATNG
HHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCHHHEEECCCEEEEEEECCC
MVTLLLAVAGWLLVARMMAPVRTLSRYLGAASEGRATPVPPEAVARNGAEFARLFLAYNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHH
LVRSMYEREDLARQLADEHRLGSLGRLTSALAHEINNPLGGLFNALATLKTHGHHAAVRK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
SSLGLLERGLVGIRDVVRTTLALYRPEQAPRPLAMADFEDLQLLIAPAARRKGVDLRFSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHEECHHHHCCCCEEECC
PVDVLLPLPSTPVRQAVLNLLLNAVSAAPPGSEVAVDASLTPTALHVIVSDRGSGLPEPA
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCC
GCLLAAGGETGGPLWGGGLGLWTTRRILDDLGASAEVERPETGGTRIRLLFPFIAPMELA
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHH
HVA
HCC
>Mature Secondary Structure
MITRLDPRQWPVTLKVPLAVAALMVLVGLALSERVLSRLGETQERQLRALAQTYLDSLSS
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AVAPAILRDDVWEVYDAVMRAQDLNKSLHPLSAVITDAEGLIIAASDPRRFPVGARLPSD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHH
LASLGAGRDFSFEAGARSATATRVLSYPGRIVGIIHATFDTSHLALERRDVVIALAATNG
HHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCHHHEEECCCEEEEEEECCC
MVTLLLAVAGWLLVARMMAPVRTLSRYLGAASEGRATPVPPEAVARNGAEFARLFLAYNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHH
LVRSMYEREDLARQLADEHRLGSLGRLTSALAHEINNPLGGLFNALATLKTHGHHAAVRK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
SSLGLLERGLVGIRDVVRTTLALYRPEQAPRPLAMADFEDLQLLIAPAARRKGVDLRFSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHEECHHHHCCCCEEECC
PVDVLLPLPSTPVRQAVLNLLLNAVSAAPPGSEVAVDASLTPTALHVIVSDRGSGLPEPA
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCC
GCLLAAGGETGGPLWGGGLGLWTTRRILDDLGASAEVERPETGGTRIRLLFPFIAPMELA
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHH
HVA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104615; 2509430; 9384377 [H]