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The map label for this gene is yfeH [C]

Identifier: 154247829

GI number: 154247829

Start: 4323609

End: 4324745

Strand: Direct

Name: yfeH [C]

Synonym: Xaut_3906

Alternate gene names: 154247829

Gene position: 4323609-4324745 (Clockwise)

Preceding gene: 154247828

Following gene: 154247832

Centisome position: 81.44

GC content: 67.46

Gene sequence:

>1137_bases
ATGGGCGATGGGGCAGGGAATGGTCGCGGGCGGGCAGGTCTCACGCCTCTCTCACGCCTCACCGTTCTGCTCATGTTGTC
ACGACTGAAGCTCGATCCGTTCGTCGTCGCCCTCGCCCTCACCGTCTCCCTGGCCCTGGTCTGGCCGCAGCCCGGCGTCA
CGGGCGGCGTGCTCCATGCCGACAAGGCCGCGAGCTGGGGCGTCGCGCTAATCTTTTTCCTTTATGGCATCTCGCTGTCG
CCGAAGCGGCTGCTTGAAAGCGCGACCCGCTGGGAGCTGCACCTGATCGTGCAGCTGGGCACCTTCCTGCTGTTTCCCGC
GGTGGTCATGGGGCTGCTGGCCCTGGTGGGCGACCGCCTGCCGGAGGCAGTGGCGACGGGATTCTTCTTCCTCGCCGCCC
TGCCGTCCACGGTCTCCTCCTCGGTGGCGATGACCTCGCTGGCGCGGGGCAACGTGCCGGTGGCCATCTTCAATGCCTCG
ATCTCCAGCCTGATCGGCGTGTTCGCCACGCCCGTGCTCATGGCCTGGTACCTGCACACGGTGGGCGGGGGGATGACACT
CGGTCCGGTGATCCTGAAGCTGATCATCCTGGTGATCCTGCCGCTGGCGGTGGGACAGGCGGCGCGGCCGCTGCTGCTGA
AGCTGGTGGAGCGTCATCGTCAGGTGGTGCGCATCGCCGACCGGGCGGTGATCCTGGCCATTGTCTACAATTCGTTCTGC
GACAGCGTCGCCGCCGGCGTGTGGAAGGGCCACAGCCCGGTGCTGCTGCTGGAGATCGTGGCCGGCGTGCTGGCGCTGTT
TTCCGTGGTCTACCTGCTGATCGGGGTCGCCTGCCGGGTCTTCGGCTTCTCCCGGCCCGACACCATTGCGGTGGTGTTCT
GCGCCTCGAAGAAGTCGCTCGCCACCGGCCTGCCCATGGCGCAGGTGATGTTCAACGGGTCGCCGGACCTGTCGCTGATC
ATCACCCCGATCATGCTCTACCACTTCCTGCAACTGGTCATCGTCGGCATCATCGCCGGCCGCAGCGGGGCGCTGGAGGC
GGAGGAGACCGAGCCCGCCGTTCTCGCCGAGGACGATGATGACCTCGTGCCCGACGCGGTGCCGCAGCATCGGCAGGCGT
CCTCGACCGCCTCCTGA

Upstream 100 bases:

>100_bases
GTATATTGTCGACATGAAGATCGGCGAACGTCGGCGCAGACCGCTTCAGGCGGGATGAGCAAGGCACATAAGCGCACGCA
CGGGAGCCTCAGGCGACCGG

Downstream 100 bases:

>100_bases
TGGACGCTCAGGCGGTGGGGATCTCCTCCACCGCCAGCTCGAAGGTAATGAGCACCGGATTGGCGCCCGGCACCAGCCGG
CCTTCGGCCATGGCGCCGGT

Product: bile acid:sodium symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MGDGAGNGRGRAGLTPLSRLTVLLMLSRLKLDPFVVALALTVSLALVWPQPGVTGGVLHADKAASWGVALIFFLYGISLS
PKRLLESATRWELHLIVQLGTFLLFPAVVMGLLALVGDRLPEAVATGFFFLAALPSTVSSSVAMTSLARGNVPVAIFNAS
ISSLIGVFATPVLMAWYLHTVGGGMTLGPVILKLIILVILPLAVGQAARPLLLKLVERHRQVVRIADRAVILAIVYNSFC
DSVAAGVWKGHSPVLLLEIVAGVLALFSVVYLLIGVACRVFGFSRPDTIAVVFCASKKSLATGLPMAQVMFNGSPDLSLI
ITPIMLYHFLQLVIVGIIAGRSGALEAEETEPAVLAEDDDDLVPDAVPQHRQASSTAS

Sequences:

>Translated_378_residues
MGDGAGNGRGRAGLTPLSRLTVLLMLSRLKLDPFVVALALTVSLALVWPQPGVTGGVLHADKAASWGVALIFFLYGISLS
PKRLLESATRWELHLIVQLGTFLLFPAVVMGLLALVGDRLPEAVATGFFFLAALPSTVSSSVAMTSLARGNVPVAIFNAS
ISSLIGVFATPVLMAWYLHTVGGGMTLGPVILKLIILVILPLAVGQAARPLLLKLVERHRQVVRIADRAVILAIVYNSFC
DSVAAGVWKGHSPVLLLEIVAGVLALFSVVYLLIGVACRVFGFSRPDTIAVVFCASKKSLATGLPMAQVMFNGSPDLSLI
ITPIMLYHFLQLVIVGIIAGRSGALEAEETEPAVLAEDDDDLVPDAVPQHRQASSTAS
>Mature_377_residues
GDGAGNGRGRAGLTPLSRLTVLLMLSRLKLDPFVVALALTVSLALVWPQPGVTGGVLHADKAASWGVALIFFLYGISLSP
KRLLESATRWELHLIVQLGTFLLFPAVVMGLLALVGDRLPEAVATGFFFLAALPSTVSSSVAMTSLARGNVPVAIFNASI
SSLIGVFATPVLMAWYLHTVGGGMTLGPVILKLIILVILPLAVGQAARPLLLKLVERHRQVVRIADRAVILAIVYNSFCD
SVAAGVWKGHSPVLLLEIVAGVLALFSVVYLLIGVACRVFGFSRPDTIAVVFCASKKSLATGLPMAQVMFNGSPDLSLII
TPIMLYHFLQLVIVGIIAGRSGALEAEETEPAVLAEDDDDLVPDAVPQHRQASSTAS

Specific function: Unknown

COG id: COG0385

COG function: function code R; Predicted Na+-dependent transporter

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yfeH [H]

Homologues:

Organism=Homo sapiens, GI71725371, Length=320, Percent_Identity=30.625, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI14149785, Length=143, Percent_Identity=33.5664335664336, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788749, Length=329, Percent_Identity=33.7386018237082, Blast_Score=162, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323677, Length=389, Percent_Identity=20.8226221079692, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002657
- InterPro:   IPR016833 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39855; Mature: 39724

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDGAGNGRGRAGLTPLSRLTVLLMLSRLKLDPFVVALALTVSLALVWPQPGVTGGVLHA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEC
DKAASWGVALIFFLYGISLSPKRLLESATRWELHLIVQLGTFLLFPAVVMGLLALVGDRL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PEAVATGFFFLAALPSTVSSSVAMTSLARGNVPVAIFNASISSLIGVFATPVLMAWYLHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
VGGGMTLGPVILKLIILVILPLAVGQAARPLLLKLVERHRQVVRIADRAVILAIVYNSFC
HCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSVAAGVWKGHSPVLLLEIVAGVLALFSVVYLLIGVACRVFGFSRPDTIAVVFCASKKSL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHH
ATGLPMAQVMFNGSPDLSLIITPIMLYHFLQLVIVGIIAGRSGALEAEETEPAVLAEDDD
HHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCC
DLVPDAVPQHRQASSTAS
CCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
GDGAGNGRGRAGLTPLSRLTVLLMLSRLKLDPFVVALALTVSLALVWPQPGVTGGVLHA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEC
DKAASWGVALIFFLYGISLSPKRLLESATRWELHLIVQLGTFLLFPAVVMGLLALVGDRL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PEAVATGFFFLAALPSTVSSSVAMTSLARGNVPVAIFNASISSLIGVFATPVLMAWYLHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
VGGGMTLGPVILKLIILVILPLAVGQAARPLLLKLVERHRQVVRIADRAVILAIVYNSFC
HCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSVAAGVWKGHSPVLLLEIVAGVLALFSVVYLLIGVACRVFGFSRPDTIAVVFCASKKSL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHH
ATGLPMAQVMFNGSPDLSLIITPIMLYHFLQLVIVGIIAGRSGALEAEETEPAVLAEDDD
HHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCC
DLVPDAVPQHRQASSTAS
CCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1849605 [H]