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The map label for this gene is yfjP [H]

Identifier: 154247764

GI number: 154247764

Start: 4258436

End: 4259089

Strand: Direct

Name: yfjP [H]

Synonym: Xaut_3841

Alternate gene names: 154247764

Gene position: 4258436-4259089 (Clockwise)

Preceding gene: 154247762

Following gene: 154247765

Centisome position: 80.21

GC content: 76.15

Gene sequence:

>654_bases
ATGATGAGCGAGCCGCACCTGTCCGACCAGCGGGCGTTCGACCGGGCGCTGGACGATCTGCTCGCCCTCGATCCGCGTCT
CGTGCCGCTGGTGGATCTGGCCGGCCGGCCGACCCTGCGCCGGCGCCCGCCGGGCTTTGCGGGGCTCGCGGCGGTGGTGG
TGGCGCAGCAGCTTTCGGTGGCCTCGGCGCGGGCCATCCATGGCCGGCTGGAATCAACCCTCGGCGGCGCGCCAAGCGTG
GAGGCCATGCTGGCCGCGACCCCGGAGGCCCTGCGCGCCGCCGGCCTCTCCGCGCCCAAGATCCGCACCCTCACCGGCAT
TGCCCGCGCGCTGGCGGAGGGGGCGGTGGACCTCGACGCCGTGGCCCGCATGGAGGCGGACGCCGCCGCCGAGACACTCA
CCCGCCTGCCCGGCGTGGGGCTTTGGACCGCCGACATCTACCTGCTGTTCTGCCTCGGCCGGGCCGATGCCTTTCCCCAC
GGCGACCTCGCCCTGCAGGTGGCGCTGGGCGAGGCCTTCGACCTGCCGGGGCGCGCGACGCCCCAGGGCCTGCGGGCGGT
GGCGGAGGACTGGCGGCCGCTGCGCGGCGTGGCGGCCCATCTGCTGTGGGCGTATTATGGTGCGCGGCGCACCCGTCAGG
GCGCGCCGGCCTGA

Upstream 100 bases:

>100_bases
AGGGGATCCCGGTTCGCGTGAACGAGATGCGTGGACACAGGATTTTCGCGCGCAGTGGGCTGATGCGCTTGGAACGCGTG
TCAGCACGAGGTGGGAGGGA

Downstream 100 bases:

>100_bases
GCGTTTCGAAGCCCACTCATTTGAAGCCCACCCATTGGTAATGCCATGACTTTTCCCAGCGGCTCCTTTCCCCTTGATGG
CGTGTCCCTCGACGAGCCGG

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MMSEPHLSDQRAFDRALDDLLALDPRLVPLVDLAGRPTLRRRPPGFAGLAAVVVAQQLSVASARAIHGRLESTLGGAPSV
EAMLAATPEALRAAGLSAPKIRTLTGIARALAEGAVDLDAVARMEADAAAETLTRLPGVGLWTADIYLLFCLGRADAFPH
GDLALQVALGEAFDLPGRATPQGLRAVAEDWRPLRGVAAHLLWAYYGARRTRQGAPA

Sequences:

>Translated_217_residues
MMSEPHLSDQRAFDRALDDLLALDPRLVPLVDLAGRPTLRRRPPGFAGLAAVVVAQQLSVASARAIHGRLESTLGGAPSV
EAMLAATPEALRAAGLSAPKIRTLTGIARALAEGAVDLDAVARMEADAAAETLTRLPGVGLWTADIYLLFCLGRADAFPH
GDLALQVALGEAFDLPGRATPQGLRAVAEDWRPLRGVAAHLLWAYYGARRTRQGAPA
>Mature_217_residues
MMSEPHLSDQRAFDRALDDLLALDPRLVPLVDLAGRPTLRRRPPGFAGLAAVVVAQQLSVASARAIHGRLESTLGGAPSV
EAMLAATPEALRAAGLSAPKIRTLTGIARALAEGAVDLDAVARMEADAAAETLTRLPGVGLWTADIYLLFCLGRADAFPH
GDLALQVALGEAFDLPGRATPQGLRAVAEDWRPLRGVAAHLLWAYYGARRTRQGAPA

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 22850; Mature: 22850

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSEPHLSDQRAFDRALDDLLALDPRLVPLVDLAGRPTLRRRPPGFAGLAAVVVAQQLSV
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ASARAIHGRLESTLGGAPSVEAMLAATPEALRAAGLSAPKIRTLTGIARALAEGAVDLDA
HHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHH
VARMEADAAAETLTRLPGVGLWTADIYLLFCLGRADAFPHGDLALQVALGEAFDLPGRAT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHCCCCCCC
PQGLRAVAEDWRPLRGVAAHLLWAYYGARRTRQGAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMSEPHLSDQRAFDRALDDLLALDPRLVPLVDLAGRPTLRRRPPGFAGLAAVVVAQQLSV
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ASARAIHGRLESTLGGAPSVEAMLAATPEALRAAGLSAPKIRTLTGIARALAEGAVDLDA
HHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHH
VARMEADAAAETLTRLPGVGLWTADIYLLFCLGRADAFPHGDLALQVALGEAFDLPGRAT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHCCCCCCC
PQGLRAVAEDWRPLRGVAAHLLWAYYGARRTRQGAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]