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The map label for this gene is dapA [H]

Identifier: 154247752

GI number: 154247752

Start: 4250689

End: 4251588

Strand: Direct

Name: dapA [H]

Synonym: Xaut_3829

Alternate gene names: 154247752

Gene position: 4250689-4251588 (Clockwise)

Preceding gene: 154247750

Following gene: 154247753

Centisome position: 80.07

GC content: 67.0

Gene sequence:

>900_bases
ATGTCGCCCATTTCGTCTGCGTCGCGCTTCCGCGGCTCGTTTACCGCTCTCGTCACCCCGTTCCGCGACGGCGCACTGGA
TGAAAAGGCGTTCCGCGCCTTCGTGGACTGGCAGATCGCCGAAGGCACCCACGGCCTCGTGCCGGTCGGCACCACCGGCG
AAAGCCCGACCCTCTCCCACGAGGAGCACAATCGCGTGGTGGAATGGACGGTCCAGCAGTCCGCCGGCCGGGTGCCGGTG
ATGGCGGGCGCCGGATCCAACAACACGGCGGAGGCGGTGGCCCTCGCCCAGCACGCGCAGAAGGTGGGCGCCGACGCCCT
GCTGGTGGTGACGCCCTACTACAACAAGCCCACCCAGGAAGGCCTCTACCAGCACTTCAAGGCCATCGCCAACGCGGTGG
AGCTGCCGATCTTCATCTACAACATCCCGAGCCGCTCGGTGATCGACATGTCGGTGGAGACCATGGCGCGGCTGTTCGAG
ATCAAGAACATCGCCGGCGTGAAGGATGCCACCGCGAACCTCGCCCGCGTGTCGCTGCAGCGGCAGGTGCTGGGGCCGGA
CTTCATCCAGCTCTCGGGAGAGGATGCCACGGCGCTGGGCTTCAACGCCCACGGCGGGCAGGGCTGCATCTCGGTGGCGT
CCAACGTCGCGCCGCGCCTGTGCTCGGATTTCCAGACCGCCTGCCTTTCCGGCGACTACAAGGCGGCGCTGGCGATCCAG
GACATCCTGATGCCGCTGCATACGGCGCTGTTCGTGGAGACCAATCCGGCGCCCACCAAGTATGCTCTCTCGCTGCTCGG
CAAGATGAGCGAGGAGGCGCGGCTTCCCATGGTGCCGGTCTCGGAGACCACCCGCGCCGTGGTGAAGAGCGCCATGGTGC
ATGCCGGCCTCATCAACTGA

Upstream 100 bases:

>100_bases
GTCTCAAGGTTCGCGCGCAGGCGGTCCCGGTCAATCACAAGCCCCGCGAGGCAGGCCTCACCGGCCAGCCGATAAGCCCC
AGGAACCCAAGGCGTTCGCC

Downstream 100 bases:

>100_bases
GCGCGGGTCTGCTATCCTTCGTCCATGACCAAGCTGCTGGACCAGGCCATCGCCGAGATCCGCAAGCTCTCCGACGCGGA
ACAGGACCGCGCCGCCGAGC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSPISSASRFRGSFTALVTPFRDGALDEKAFRAFVDWQIAEGTHGLVPVGTTGESPTLSHEEHNRVVEWTVQQSAGRVPV
MAGAGSNNTAEAVALAQHAQKVGADALLVVTPYYNKPTQEGLYQHFKAIANAVELPIFIYNIPSRSVIDMSVETMARLFE
IKNIAGVKDATANLARVSLQRQVLGPDFIQLSGEDATALGFNAHGGQGCISVASNVAPRLCSDFQTACLSGDYKAALAIQ
DILMPLHTALFVETNPAPTKYALSLLGKMSEEARLPMVPVSETTRAVVKSAMVHAGLIN

Sequences:

>Translated_299_residues
MSPISSASRFRGSFTALVTPFRDGALDEKAFRAFVDWQIAEGTHGLVPVGTTGESPTLSHEEHNRVVEWTVQQSAGRVPV
MAGAGSNNTAEAVALAQHAQKVGADALLVVTPYYNKPTQEGLYQHFKAIANAVELPIFIYNIPSRSVIDMSVETMARLFE
IKNIAGVKDATANLARVSLQRQVLGPDFIQLSGEDATALGFNAHGGQGCISVASNVAPRLCSDFQTACLSGDYKAALAIQ
DILMPLHTALFVETNPAPTKYALSLLGKMSEEARLPMVPVSETTRAVVKSAMVHAGLIN
>Mature_298_residues
SPISSASRFRGSFTALVTPFRDGALDEKAFRAFVDWQIAEGTHGLVPVGTTGESPTLSHEEHNRVVEWTVQQSAGRVPVM
AGAGSNNTAEAVALAQHAQKVGADALLVVTPYYNKPTQEGLYQHFKAIANAVELPIFIYNIPSRSVIDMSVETMARLFEI
KNIAGVKDATANLARVSLQRQVLGPDFIQLSGEDATALGFNAHGGQGCISVASNVAPRLCSDFQTACLSGDYKAALAIQD
ILMPLHTALFVETNPAPTKYALSLLGKMSEEARLPMVPVSETTRAVVKSAMVHAGLIN

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=241, Percent_Identity=25.7261410788382, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI13540533, Length=244, Percent_Identity=27.4590163934426, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=47.0790378006873, Blast_Score=274, Evalue=4e-75,
Organism=Escherichia coli, GI87082415, Length=298, Percent_Identity=32.5503355704698, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786463, Length=284, Percent_Identity=30.9859154929577, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789620, Length=236, Percent_Identity=29.2372881355932, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31906; Mature: 31775

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPISSASRFRGSFTALVTPFRDGALDEKAFRAFVDWQIAEGTHGLVPVGTTGESPTLSH
CCCCCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHCEEECCCCCCEEEECCCCCCCCCCC
EEHNRVVEWTVQQSAGRVPVMAGAGSNNTAEAVALAQHAQKVGADALLVVTPYYNKPTQE
HHCCCEEEEEEHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
GLYQHFKAIANAVELPIFIYNIPSRSVIDMSVETMARLFEIKNIAGVKDATANLARVSLQ
HHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RQVLGPDFIQLSGEDATALGFNAHGGQGCISVASNVAPRLCSDFQTACLSGDYKAALAIQ
HHHCCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
DILMPLHTALFVETNPAPTKYALSLLGKMSEEARLPMVPVSETTRAVVKSAMVHAGLIN
HHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SPISSASRFRGSFTALVTPFRDGALDEKAFRAFVDWQIAEGTHGLVPVGTTGESPTLSH
CCCCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHCEEECCCCCCEEEECCCCCCCCCCC
EEHNRVVEWTVQQSAGRVPVMAGAGSNNTAEAVALAQHAQKVGADALLVVTPYYNKPTQE
HHCCCEEEEEEHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
GLYQHFKAIANAVELPIFIYNIPSRSVIDMSVETMARLFEIKNIAGVKDATANLARVSLQ
HHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RQVLGPDFIQLSGEDATALGFNAHGGQGCISVASNVAPRLCSDFQTACLSGDYKAALAIQ
HHHCCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
DILMPLHTALFVETNPAPTKYALSLLGKMSEEARLPMVPVSETTRAVVKSAMVHAGLIN
HHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA